Abstract
Low-coherence spectroscopy (LCS) is a spectroscopic method that allows for quantitative and localized assessment of absorption spectra by combining reflection spectroscopy with low-coherence interferometry. We describe absorption coefficient measurements by LCS in tissue simulating phantoms with varying scattering and absorbing properties. We used LCS in the wavelength range with a spectral resolution of to obtain spectra with accuracy. We conclude that LCS is a promising technique for the in vivo determination of tissue chromophore concentrations.
© 2009 Optical Society of America
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