Abstract

We use surface-plasmon resonance in a silver film to obtain high-resolution real-time images of a transparent dielectric sample in contact with it. A new aspect of the work was the use of radially polarized illumination from a LED at 530nm to obtain speckle-free images with high spatial resolution along all orientations. The sensitivity to refractive index changes in the sample is estimated to be better than 103, and the modulation transfer function out to spatial frequency 1μm1 was measured.

© 2008 Optical Society of America

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  1. C. E. H. Berger, R. P. H. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
    [CrossRef]
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    [CrossRef]
  7. H. Kano and W. Knoll, Opt. Commun. 182, 11 (2000).
    [CrossRef]
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    [CrossRef] [PubMed]
  9. B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
    [CrossRef] [PubMed]
  10. A. Shoham, R. Vander, and S. G. Lipson, Opt. Lett. 31, 3405 (2006).
    [CrossRef] [PubMed]
  11. K. Watanabe, N. Horiguchi, and H. Kano, Appl. Opt. 46, 4985 (2007).
    [CrossRef] [PubMed]
  12. S. G. Lipson, H. Lipson, and D. S. Tannhauser, Optical Physics, 3rd ed. (Cambridge U. Press, 1995).

2007

2006

2004

G. Stabler, M. G. Somekh, and C. W. See, J. Microsc. 214, 328 (2004).
[CrossRef] [PubMed]

2000

1999

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

1996

E. M. Yeatman, Biosens. Bioelectron. 11, 635 (1996).
[CrossRef]

1994

C. E. H. Berger, R. P. H. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[CrossRef]

Bastmeyer, M.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

Bechinger, C.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

Berger, C. E. H.

C. E. H. Berger, R. P. H. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[CrossRef]

Brockman, J. M.

J. M. Brockman, B. P. Nelson, and R. M. Corn, Annu. Rev. Phys. Chem. 51, 41 (2000).
[CrossRef] [PubMed]

Corn, R. M.

J. M. Brockman, B. P. Nelson, and R. M. Corn, Annu. Rev. Phys. Chem. 51, 41 (2000).
[CrossRef] [PubMed]

Giebel, K.-F.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

Greve, J.

C. E. H. Berger, R. P. H. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[CrossRef]

Herminghaus, S.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

Horiguchi, N.

Huang, B.

B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
[CrossRef] [PubMed]

Kano, H.

Knoll, W.

H. Kano and W. Knoll, Opt. Commun. 182, 11 (2000).
[CrossRef]

Kooyman, R. P. H.

C. E. H. Berger, R. P. H. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[CrossRef]

Leiderer, P.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

Lipson, H.

S. G. Lipson, H. Lipson, and D. S. Tannhauser, Optical Physics, 3rd ed. (Cambridge U. Press, 1995).

Lipson, S. G.

A. Shoham, R. Vander, and S. G. Lipson, Opt. Lett. 31, 3405 (2006).
[CrossRef] [PubMed]

S. G. Lipson, H. Lipson, and D. S. Tannhauser, Optical Physics, 3rd ed. (Cambridge U. Press, 1995).

Liu, S. G.

Nelson, B. P.

J. M. Brockman, B. P. Nelson, and R. M. Corn, Annu. Rev. Phys. Chem. 51, 41 (2000).
[CrossRef] [PubMed]

Riedel, M.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

See, C. W.

Shoham, A.

Somekh, M. G.

Stabler, G.

G. Stabler, M. G. Somekh, and C. W. See, J. Microsc. 214, 328 (2004).
[CrossRef] [PubMed]

Tannhauser, D. S.

S. G. Lipson, H. Lipson, and D. S. Tannhauser, Optical Physics, 3rd ed. (Cambridge U. Press, 1995).

Vander, R.

Velinov, T. S.

Watanabe, K.

Weiland, U.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

Yeatman, E. M.

E. M. Yeatman, Biosens. Bioelectron. 11, 635 (1996).
[CrossRef]

Yu, F.

B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
[CrossRef] [PubMed]

Zare, R. N.

B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
[CrossRef] [PubMed]

Anal. Chem.

B. Huang, F. Yu, and R. N. Zare, Anal. Chem. 79, 2979 (2007).
[CrossRef] [PubMed]

Annu. Rev. Phys. Chem.

J. M. Brockman, B. P. Nelson, and R. M. Corn, Annu. Rev. Phys. Chem. 51, 41 (2000).
[CrossRef] [PubMed]

Appl. Opt.

Biophys. J.

K.-F. Giebel, C. Bechinger, S. Herminghaus, M. Riedel, P. Leiderer, U. Weiland, and M. Bastmeyer, Biophys. J. 76, 509 (1999).
[CrossRef] [PubMed]

Biosens. Bioelectron.

E. M. Yeatman, Biosens. Bioelectron. 11, 635 (1996).
[CrossRef]

J. Microsc.

G. Stabler, M. G. Somekh, and C. W. See, J. Microsc. 214, 328 (2004).
[CrossRef] [PubMed]

Opt. Commun.

H. Kano and W. Knoll, Opt. Commun. 182, 11 (2000).
[CrossRef]

Opt. Lett.

Rev. Sci. Instrum.

C. E. H. Berger, R. P. H. Kooyman, and J. Greve, Rev. Sci. Instrum. 65, 2829 (1994).
[CrossRef]

Other

S. G. Lipson, H. Lipson, and D. S. Tannhauser, Optical Physics, 3rd ed. (Cambridge U. Press, 1995).

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Figures (5)

Fig. 1
Fig. 1

Dark resonance ring observed in the annular aperture as seen in the back focal plane.

Fig. 2
Fig. 2

Optical setup used for the experiments.

Fig. 3
Fig. 3

Resolution target image with 0.5 μ m squares.

Fig. 4
Fig. 4

Measured MTF of the system, compared with the theoretical MTF (dashed curve). Note the peak at the resolution limit, typical of annular illumination.

Fig. 5
Fig. 5

Image of a blood smear: above, with SPR contrast; below, bright-field image.

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