Abstract

The spectroscopic content within optical coherence tomography (OCT) data can provide a wealth of information. Spectroscopic OCT methods are frequently limited by time-frequency trade-offs that limit high spectral and spatial resolution simultaneously. We present spectroscopic spectral-domain optical coherence microscopy performed with a multimodality microscope. Restricting the spatial extent of the signal by using high-numerical-aperture optics makes high-resolution spectroscopic information accessible, facilitated with spectral-domain detection. Simultaneous acquisition of multiphoton microscopy images is used to validate tissue structure and localization of nuclei within individual cells.

© 2006 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Ultrahigh speed spectral-domain optical coherence microscopy

Hsiang-Chieh Lee, Jonathan J. Liu, Yuri Sheikine, Aaron D. Aguirre, James L. Connolly, and James G. Fujimoto
Biomed. Opt. Express 4(8) 1236-1254 (2013)

Spectroscopic imaging with spectral domain visible light optical coherence microscopy in Alzheimer’s disease brain samples

Antonia Lichtenegger, Danielle J. Harper, Marco Augustin, Pablo Eugui, Martina Muck, Johanna Gesperger, Christoph K. Hitzenberger, Adelheid Woehrer, and Bernhard Baumann
Biomed. Opt. Express 8(9) 4007-4025 (2017)

Spectral-domain optical coherence phase and multiphoton microscopy

Chulmin Joo, Ki Hean Kim, and Johannes F. de Boer
Opt. Lett. 32(6) 623-625 (2007)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription