Abstract

A novel swept-laser-based Fourier-domain optical coherence tomography system using an electro-optic phase modulator was demonstrated. The imaging range was doubled by cancellation of the mirror image. The elimination of low-frequency noises resulting from dc and autocorrelation terms increased the sensitivity by 20 dB.

© 2005 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
    [CrossRef] [PubMed]
  2. A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, Opt. Commun. 117, 43 (1995).
    [CrossRef]
  3. G. Hausler and M. W. Lindner, J. Biomed. Opt. 3, 21 (1998).
    [CrossRef]
  4. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, Opt. Express 11, 889 (2003), http://www.opticsexpress.org .
    [CrossRef] [PubMed]
  5. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, Opt. Lett. 28, 2067 (2003).
    [CrossRef] [PubMed]
  6. M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, Opt. Express 11, 2183 (2003), http://www.opticsexpress.org .
    [CrossRef] [PubMed]
  7. S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, Opt. Express 11, 2953 (2003).
    [CrossRef] [PubMed]
  8. M. Wojtkowski, A. Kowalczyk, R. Leitgeb, and A. F. Fercher, Opt. Lett. 27, 1415 (2002).
    [CrossRef]
  9. R. A. Leitgeb, C. K. Hitzenberger, A. F. Fercher, and T. Bajraszewski, Opt. Lett. 28, 2201 (2003).
    [CrossRef] [PubMed]
  10. M. A. Choma, C. Yang, and J. A. Izatt, Opt. Lett. 28, 2162 (2003).
    [CrossRef] [PubMed]
  11. G. J. Tearney, B. E. Bouma, and J. G. Fujimoto, Opt. Lett. 22, 1811 (1997).
    [CrossRef]
  12. M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, Opt. Express 12, 2404 (2004), http://www.opticsexpress.org .
    [CrossRef] [PubMed]
  13. B. Cense, N. A. Nassif, T. C. Chen, M. C. Pierce, S. Yun, B. H. Park, B. E. Bouma, G. J. Tearney, and J. F. de Boer, Opt. Express 12, 2435 (2004), http://www.opticsexpress.org .
    [CrossRef] [PubMed]
  14. W. V. Sorin and D. M. Baney, IEEE Photon. Technol. Lett. 4, 1404 (1992).
    [CrossRef]

2004 (2)

2003 (6)

2002 (1)

1998 (1)

G. Hausler and M. W. Lindner, J. Biomed. Opt. 3, 21 (1998).
[CrossRef]

1997 (1)

1995 (1)

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

1992 (1)

W. V. Sorin and D. M. Baney, IEEE Photon. Technol. Lett. 4, 1404 (1992).
[CrossRef]

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Bajraszewski, T.

Baney, D. M.

W. V. Sorin and D. M. Baney, IEEE Photon. Technol. Lett. 4, 1404 (1992).
[CrossRef]

Bouma, B. E.

Cense, B.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Chen, T. C.

Choma, M. A.

de Boer, J. F.

Duker, J. S.

El-Zaiat, S. Y.

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

Fercher, A. F.

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Fujimoto, J. G.

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Hausler, G.

G. Hausler and M. W. Lindner, J. Biomed. Opt. 3, 21 (1998).
[CrossRef]

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Hitzenberger, C. K.

Huang, D.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Iftimia, N.

Izatt, J. A.

Kamp, G.

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

Ko, T. H.

Kowalczyk, A.

Leitgeb, R.

Leitgeb, R. A.

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Lindner, M. W.

G. Hausler and M. W. Lindner, J. Biomed. Opt. 3, 21 (1998).
[CrossRef]

Nassif, N. A.

Park, B. H.

Pierce, M. C.

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Sarunic, M. V.

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Sorin, W. V.

W. V. Sorin and D. M. Baney, IEEE Photon. Technol. Lett. 4, 1404 (1992).
[CrossRef]

Srinivasan, V. J.

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Swanson, E. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Tearney, G. J.

Wojtkowski, M.

Yang, C.

Yang, C. H.

Yun, S.

Yun, S. H.

IEEE Photon. Technol. Lett. (1)

W. V. Sorin and D. M. Baney, IEEE Photon. Technol. Lett. 4, 1404 (1992).
[CrossRef]

J. Biomed. Opt. (1)

G. Hausler and M. W. Lindner, J. Biomed. Opt. 3, 21 (1998).
[CrossRef]

Opt. Commun. (1)

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, Opt. Commun. 117, 43 (1995).
[CrossRef]

Opt. Express (5)

Opt. Lett. (5)

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (4)

Fig. 1
Fig. 1

Schematic of the FDOCT system. Phase Mod., phase modulator; Colli., collimator; Atte., adjustable neutral-density attenuator; M, mirror; L, lens; FFP, 100-GHz fiber Fabry–Perot interferometer; D1, D2, photodetectors.

Fig. 2
Fig. 2

Block diagram of conversion from time fringe signal Γt to complex analytical depth-encoded signal S˜z.

Fig. 3
Fig. 3

Images of rabbit cornea obtained with the FDOCT system (a) without and (b) with an EO phase modulator.

Fig. 4
Fig. 4

Sensitivities measured with a -57.6dB reflector. Blue, without an EO phase modulator; red, with an EO phase modulator.

Equations (4)

Equations on this page are rendered with MathJax. Learn more.

Ik=SkRR+Sk-+-+RSΔzRSΔz1/2×expikΔz-Δz+ϕΔz-ϕΔzdΔzdΔz+2SkRR-RSΔzcoskΔz+ϕΔzdΔz,
coskΔzFT12δz-Δz+δz+Δz.
coskΔz-Ωt=coskΔz+Ωm-Ωk0m=coskΔz+z0-Ωk0m kΔz FT 12δz-Δz-z0expiΩk0m+δz+Δz+z0exp-iΩk0m,
Hv=0v<01v0,

Metrics