Abstract

We report a compact, high-power, fiber-based source for ultrahigh-resolution optical coherence tomography (OCT) near 1μm. The practical source is based on a short-pulse, ytterbium-doped fiber laser and on generation of a continuum spectrum in a photonic crystal fiber. The broadband emission has an average power of 140mW and offers an axial resolution of 2.1μm in air (<1.6μm in biological tissue). The generation of a broad bandwidth is robust and efficient. We demonstrate ultrahigh-resolution, time-domain OCT imaging of in vitro and in vivo biological tissues.

© 2005 Optical Society of America

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  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
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2004 (2)

2003 (6)

2002 (1)

2001 (1)

2000 (1)

1994 (1)

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Aguirre, A. D.

Birks, T. A.

Bizheva, K.

Bourquin, S.

Buckley, J.

Bunting, U.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Chen, Y.

Chen, Z.

Chuck, R. S.

Chudoba, C.

Coen, S.

de Matos, C. J. S.

Drexler, W.

Dudley, J. M.

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Fujimoto, J. G.

Gapontsev, V. P.

Ghanta, R. K.

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Hartl, I.

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Hermann, B.

Hoelzenbein, T.

Holzwarth, R.

Hsiung, P.

Huang, D.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Ilday, F. Ö.

Ko, T. H.

Kopf, D.

Li, X. D.

Lim, H.

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Mei, M.

Nelson, J. S.

Pehamberger, H.

Popov, S. V.

Povazay, B.

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Ranka, J. K.

Reiser, B. J.

Sattmann, H.

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Stentz, A. J.

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Swanson, E. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Taylor, J. R.

Wacheck, V.

Wadsworth, W. J.

Wang, Y.

Windeler, R. S.

Wise, F. W.

Yanovsky, V. P.

Zhao, Y.

J. Biomed. Opt. (1)

W. Drexler, J. Biomed. Opt. 9, 47 (2004).
[CrossRef] [PubMed]

Opt. Express (3)

Opt. Lett. (8)

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Other (1)

American National Standards Institute, Safe Use of Lasers, ANSI Standard Z 136.1 (American National Standards Institute, New York, 1993).

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Figures (4)

Fig. 1
Fig. 1

Experimental configuration: YDFL, ytterbium-doped fiber laser; YDFA, ytterbium-doped fiber amplifier; HWP, half-wave plate; ND, neutral-density filter; FS, fused-silica prisms; HR, high-reflector mirror; PD, InGaAs photodiode.

Fig. 2
Fig. 2

Spectra of (a) the continuum from a PCF (solid curve), the output from the oscillator (dashed curve), and the amplified pulse (dotted curve) on logarithmic scales; (b) the continuum on a linear scale.

Fig. 3
Fig. 3

Autocorrelation: (a) direct temporal measurement and (b) Fourier transform from the measured power spectrum.

Fig. 4
Fig. 4

Ultrahigh-resolution OCT images of biological samples acquired with the system described here: (a) in vitro bovine bone, (b) onion skin, (c) in vivo African frog tadpole. Scale bar, 100 μ m .

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