Abstract

We present time-resolved measurements by speckle interferometry of the light scattered by a liquid medium. Measurements were performed by use of reflectance geometry and are compared with results obtained in the same conditions with a femtosecond laser and a streak camera. The setup was also tested in vivo on the forearm of a human volunteer to demonstrate the potential utility of such a setup for biomedical applications.

© 2005 Optical Society of America

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References

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  1. M. Kathleem Alam, “Noninvasive diagnoses by near-infrared spectroscopy,” Sandia report and references therein (2000), http://inforserve.sandia.gov/cgi-bin/techlib/access-control.pl/2000/002584.pdf .
  2. A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
    [Crossref] [PubMed]
  3. R. J. Hunter, M. S. Patterson, T. J. Farrell, and J. E. Haward, Phys. Med. Biol. 47, 193 (2002).
    [Crossref] [PubMed]
  4. A. Liebert, H. Wabnitz, J. Steinbrink, H. Obrig, M. Möller, R. Macdonald, A. Villringer, and H. Rinneberg, Appl. Opt. 43, 3037 (2004).
    [Crossref] [PubMed]
  5. A. Kienle and T. Glanzmann, Phys. Med. Biol. 44, 2689 (1999).
    [Crossref] [PubMed]
  6. J.-M. Tualle, H. L. Nghiem, D. Ettori, R. Sablong, E. Tinet, and S. Avrillier, J. Opt. Soc. Am. A 21, 24 (2004).
    [Crossref]
  7. J.-M. Tualle, E. Tinet, and S. Avrillier, Opt. Commun. 189, 211 (2001).
    [Crossref]
  8. J.-M. Tualle, “Method for analysing a diffusive sample by time resolution measurement,” international patentWO0188507 (November22, 2001).
  9. D. J. Pine, D. A. Weitz, P. M. Chaikin, and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134 (1988).
    [Crossref] [PubMed]
  10. H. Monod and R. Flandrois, Physiologie du Sport (Editions Mason, Paris, 1994).

2004 (3)

2002 (1)

R. J. Hunter, M. S. Patterson, T. J. Farrell, and J. E. Haward, Phys. Med. Biol. 47, 193 (2002).
[Crossref] [PubMed]

2001 (1)

J.-M. Tualle, E. Tinet, and S. Avrillier, Opt. Commun. 189, 211 (2001).
[Crossref]

1999 (1)

A. Kienle and T. Glanzmann, Phys. Med. Biol. 44, 2689 (1999).
[Crossref] [PubMed]

1988 (1)

D. J. Pine, D. A. Weitz, P. M. Chaikin, and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134 (1988).
[Crossref] [PubMed]

Avrillier, S.

Biscotti, G.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Chaikin, P. M.

D. J. Pine, D. A. Weitz, P. M. Chaikin, and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134 (1988).
[Crossref] [PubMed]

Cubeddu, R.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Ettori, D.

Farrell, T. J.

R. J. Hunter, M. S. Patterson, T. J. Farrell, and J. E. Haward, Phys. Med. Biol. 47, 193 (2002).
[Crossref] [PubMed]

Ferrari, M.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Flandrois, R.

H. Monod and R. Flandrois, Physiologie du Sport (Editions Mason, Paris, 1994).

Glanzmann, T.

A. Kienle and T. Glanzmann, Phys. Med. Biol. 44, 2689 (1999).
[Crossref] [PubMed]

Haward, J. E.

R. J. Hunter, M. S. Patterson, T. J. Farrell, and J. E. Haward, Phys. Med. Biol. 47, 193 (2002).
[Crossref] [PubMed]

Herbolzheimer, E.

D. J. Pine, D. A. Weitz, P. M. Chaikin, and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134 (1988).
[Crossref] [PubMed]

Hunter, R. J.

R. J. Hunter, M. S. Patterson, T. J. Farrell, and J. E. Haward, Phys. Med. Biol. 47, 193 (2002).
[Crossref] [PubMed]

Kathleem Alam, M.

M. Kathleem Alam, “Noninvasive diagnoses by near-infrared spectroscopy,” Sandia report and references therein (2000), http://inforserve.sandia.gov/cgi-bin/techlib/access-control.pl/2000/002584.pdf .

Kienle, A.

A. Kienle and T. Glanzmann, Phys. Med. Biol. 44, 2689 (1999).
[Crossref] [PubMed]

Liebert, A.

Macdonald, R.

Möller, M.

Monod, H.

H. Monod and R. Flandrois, Physiologie du Sport (Editions Mason, Paris, 1994).

Nghiem, H. L.

Obrig, H.

Patterson, M. S.

R. J. Hunter, M. S. Patterson, T. J. Farrell, and J. E. Haward, Phys. Med. Biol. 47, 193 (2002).
[Crossref] [PubMed]

Pifferi, A.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Pine, D. J.

D. J. Pine, D. A. Weitz, P. M. Chaikin, and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134 (1988).
[Crossref] [PubMed]

Quaresima, V.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Rinneberg, H.

Sablong, R.

Spinelli, L.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Steinbrink, J.

Taroni, P.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Tinet, E.

Torricelli, A.

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

Tualle, J.-M.

J.-M. Tualle, H. L. Nghiem, D. Ettori, R. Sablong, E. Tinet, and S. Avrillier, J. Opt. Soc. Am. A 21, 24 (2004).
[Crossref]

J.-M. Tualle, E. Tinet, and S. Avrillier, Opt. Commun. 189, 211 (2001).
[Crossref]

J.-M. Tualle, “Method for analysing a diffusive sample by time resolution measurement,” international patentWO0188507 (November22, 2001).

Villringer, A.

Wabnitz, H.

Weitz, D. A.

D. J. Pine, D. A. Weitz, P. M. Chaikin, and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134 (1988).
[Crossref] [PubMed]

Appl. Opt. (1)

J. Opt. Soc. Am. A (1)

Opt. Commun. (1)

J.-M. Tualle, E. Tinet, and S. Avrillier, Opt. Commun. 189, 211 (2001).
[Crossref]

Phys. Med. Biol. (3)

A. Kienle and T. Glanzmann, Phys. Med. Biol. 44, 2689 (1999).
[Crossref] [PubMed]

A. Torricelli, V. Quaresima, A. Pifferi, G. Biscotti, L. Spinelli, P. Taroni, M. Ferrari, and R. Cubeddu, Phys. Med. Biol. 49, 685 (2004).
[Crossref] [PubMed]

R. J. Hunter, M. S. Patterson, T. J. Farrell, and J. E. Haward, Phys. Med. Biol. 47, 193 (2002).
[Crossref] [PubMed]

Phys. Rev. Lett. (1)

D. J. Pine, D. A. Weitz, P. M. Chaikin, and E. Herbolzheimer, Phys. Rev. Lett. 60, 1134 (1988).
[Crossref] [PubMed]

Other (3)

H. Monod and R. Flandrois, Physiologie du Sport (Editions Mason, Paris, 1994).

J.-M. Tualle, “Method for analysing a diffusive sample by time resolution measurement,” international patentWO0188507 (November22, 2001).

M. Kathleem Alam, “Noninvasive diagnoses by near-infrared spectroscopy,” Sandia report and references therein (2000), http://inforserve.sandia.gov/cgi-bin/techlib/access-control.pl/2000/002584.pdf .

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Figures (3)

Fig. 1
Fig. 1

Experimental setup. AOM, acousto-optic modulator.

Fig. 2
Fig. 2

Comparison of the time-resolved reflectance of the liquid phantom measured with the interferometric setup (open circles) and with a streak camera (solid curve).

Fig. 3
Fig. 3

Time-resolved reflectance of the forearm of a volunteer measured with interferometric setup (open circles) and with a streak camera (solid curve).

Tables (2)

Tables Icon

Table 1 Optical Coefficients Obtained for the Liquid Phantom

Tables Icon

Table 2 Optical Coefficients Obtained for the Forearm of a Volunteer

Equations (3)

Equations on this page are rendered with MathJax. Learn more.

Reft,τ=sin2n2πftexpiΔΩτ cos2πft
Sdc2τg2τ-τϕτdτ,
t0=λ24π2DB=3ηaλ22π kT,

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