Abstract

A technique is developed to simultaneously acquire ultrasound and photoacoustic (PA) images based on a linear transducer array. The system uses conventional ultrasound for rapid identification of potential targets. After a target is identified, the ultrasound echo and PA signals can be simultaneously obtained with optimized excitation and a signal collection sequence. The corresponding ultrasound impedance and optical absorption images are reconstructed with a phase-controlled algorithm. The approach can effectively reduce the artifacts associated with a conventional filter backprojection algorithm used in PA imaging by linear scanning. The technique provides a new approach for practical applications.

© 2004 Optical Society of America

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    [CrossRef]

2004 (1)

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

2003 (4)

K. P. Köstli and P. C. Beard, Appl. Opt. 42, 1899 (2003).
[CrossRef]

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Y. Yao, D. Xing, K. Ueda, and Q. Chen, J. Appl. Phys. 94, 1278 (2003).
[CrossRef]

R. A. Kruger, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, Med. Phys. 30, 856 (2003).
[CrossRef] [PubMed]

2002 (1)

J. J. Niederhauser, D. Frauchiger, H. P. Weber, and M. Frenz, Appl. Phys. Lett. 81, 571 (2002).
[CrossRef]

2001 (2)

K. Larin, O. Hartrump, I. Larina, and R. Esenaliev, Proc. SPIE 4256, 147 (2001).
[CrossRef]

A. A. Oraevsky, A. A. Karabutov, and S. V. Solomatin, Proc. SPIE 4256, 6 (2001).
[CrossRef]

1998 (1)

1995 (1)

R. A. Kruger and L. P. Fang, Med. Phys. 22, 1605 (1995).
[CrossRef] [PubMed]

1994 (1)

A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, Proc. SPIE 2134A, 122 (1994).

Bai, J.

J. Bai, The Principle of Diagnostic Ultrasound Imaging (Tsinghua U. Press, Beijing, 1998).

Beard, P. C.

Chen, Q.

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

Y. Yao, D. Xing, K. Ueda, and Q. Chen, J. Appl. Phys. 94, 1278 (2003).
[CrossRef]

de Mul, F. F. M.

Dekker, A.

Esenaliev, R.

K. Larin, O. Hartrump, I. Larina, and R. Esenaliev, Proc. SPIE 4256, 147 (2001).
[CrossRef]

Esenaliev, R. O.

A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, Proc. SPIE 2134A, 122 (1994).

Fang, L. P.

R. A. Kruger and L. P. Fang, Med. Phys. 22, 1605 (1995).
[CrossRef] [PubMed]

Frauchiger, D.

J. J. Niederhauser, D. Frauchiger, H. P. Weber, and M. Frenz, Appl. Phys. Lett. 81, 571 (2002).
[CrossRef]

Frenz, M.

J. J. Niederhauser, D. Frauchiger, H. P. Weber, and M. Frenz, Appl. Phys. Lett. 81, 571 (2002).
[CrossRef]

Hartrump, O.

K. Larin, O. Hartrump, I. Larina, and R. Esenaliev, Proc. SPIE 4256, 147 (2001).
[CrossRef]

Hoelen, G. A.

Jacques, S. L.

A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, Proc. SPIE 2134A, 122 (1994).

Karabutov, A. A.

A. A. Oraevsky, A. A. Karabutov, and S. V. Solomatin, Proc. SPIE 4256, 6 (2001).
[CrossRef]

Kiser, W. L.

R. A. Kruger, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, Med. Phys. 30, 856 (2003).
[CrossRef] [PubMed]

Kolkman, R. G. M.

Köstli, K. P.

Kruger, G. A.

R. A. Kruger, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, Med. Phys. 30, 856 (2003).
[CrossRef] [PubMed]

Kruger, R. A.

R. A. Kruger, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, Med. Phys. 30, 856 (2003).
[CrossRef] [PubMed]

R. A. Kruger and L. P. Fang, Med. Phys. 22, 1605 (1995).
[CrossRef] [PubMed]

Ku, G.

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Larin, K.

K. Larin, O. Hartrump, I. Larina, and R. Esenaliev, Proc. SPIE 4256, 147 (2001).
[CrossRef]

Larina, I.

K. Larin, O. Hartrump, I. Larina, and R. Esenaliev, Proc. SPIE 4256, 147 (2001).
[CrossRef]

Niederhauser, J. J.

J. J. Niederhauser, D. Frauchiger, H. P. Weber, and M. Frenz, Appl. Phys. Lett. 81, 571 (2002).
[CrossRef]

Oraevsky, A. A.

A. A. Oraevsky, A. A. Karabutov, and S. V. Solomatin, Proc. SPIE 4256, 6 (2001).
[CrossRef]

A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, Proc. SPIE 2134A, 122 (1994).

Pang, Y. J.

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Reinecke, D. R.

R. A. Kruger, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, Med. Phys. 30, 856 (2003).
[CrossRef] [PubMed]

Solomatin, S. V.

A. A. Oraevsky, A. A. Karabutov, and S. V. Solomatin, Proc. SPIE 4256, 6 (2001).
[CrossRef]

Stoica, G.

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Tan, Y.

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

Tittel, F. K.

A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, Proc. SPIE 2134A, 122 (1994).

Ueda, K.

Y. Yao, D. Xing, K. Ueda, and Q. Chen, J. Appl. Phys. 94, 1278 (2003).
[CrossRef]

Wang, L. V.

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Wang, X. D.

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Wang, Y.

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

Weber, H. P.

J. J. Niederhauser, D. Frauchiger, H. P. Weber, and M. Frenz, Appl. Phys. Lett. 81, 571 (2002).
[CrossRef]

Xie, X. Y.

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Xing, D.

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

Y. Yao, D. Xing, K. Ueda, and Q. Chen, J. Appl. Phys. 94, 1278 (2003).
[CrossRef]

Yao, Y.

Y. Yao, D. Xing, K. Ueda, and Q. Chen, J. Appl. Phys. 94, 1278 (2003).
[CrossRef]

Yin, B. Zh.

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

Zeng, Y. G.

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

Appl. Opt. (1)

Appl. Phys. Lett. (1)

J. J. Niederhauser, D. Frauchiger, H. P. Weber, and M. Frenz, Appl. Phys. Lett. 81, 571 (2002).
[CrossRef]

J. Appl. Phys. (1)

Y. Yao, D. Xing, K. Ueda, and Q. Chen, J. Appl. Phys. 94, 1278 (2003).
[CrossRef]

Med. Phys. (2)

R. A. Kruger, W. L. Kiser, D. R. Reinecke, and G. A. Kruger, Med. Phys. 30, 856 (2003).
[CrossRef] [PubMed]

R. A. Kruger and L. P. Fang, Med. Phys. 22, 1605 (1995).
[CrossRef] [PubMed]

Nat. Biotechnol. (1)

X. D. Wang, Y. J. Pang, G. Ku, X. Y. Xie, G. Stoica, and L. V. Wang, Nat. Biotechnol. 21, 803 (2003).
[CrossRef] [PubMed]

Opt. Lett. (1)

Phys. Med. Biol. (1)

B. Zh. Yin, D. Xing, Y. Wang, Y. G. Zeng, Y. Tan, and Q. Chen, Phys. Med. Biol. 49, 1339 (2004).
[CrossRef] [PubMed]

Proc. SPIE (3)

A. A. Oraevsky, A. A. Karabutov, and S. V. Solomatin, Proc. SPIE 4256, 6 (2001).
[CrossRef]

A. A. Oraevsky, S. L. Jacques, R. O. Esenaliev, and F. K. Tittel, Proc. SPIE 2134A, 122 (1994).

K. Larin, O. Hartrump, I. Larina, and R. Esenaliev, Proc. SPIE 4256, 147 (2001).
[CrossRef]

Other (1)

J. Bai, The Principle of Diagnostic Ultrasound Imaging (Tsinghua U. Press, Beijing, 1998).

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Figures (3)

Fig. 1
Fig. 1

(a) Physical locations of numerical simulation sound sources, (b) image reconstructed by the filter backprojection algorithm, (c) image reconstructed by the phase-controlled focusing algorithm.

Fig. 2
Fig. 2

Typical temporal signal recorded by a cluster of transducers.

Fig. 3
Fig. 3

(a) Ultrasound image of the phantom with embedded absorbers. The transducer is located on the top of the image (i.e., y=0) and is parallel to the x axis. (b) Reconstructed PA image of the phantom with its embedded absorbers.

Equations (2)

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r-riv0tArdr=4πcpβI0v0τ0t0tpr,τdτ,
pr,τ=IFFTpr,ωIω121+cosπωω0,

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