An optical-fiber-based multichannel polarization-sensitive Mueller optical coherence tomography (OCT) system was built to acquire the Jones or Mueller matrix of a scattering medium, such as biological tissue. For the first time to our knowledge, fiber-based polarization-sensitive OCT was dynamically calibrated to eliminate the polarization distortion caused by the single-mode optical fiber in the sample arm, thereby overcoming a key technical impediment to the application of optical fibers in this technology. The round-trip Jones matrix of the sampling fiber was acquired from the reflecting surface of the sample for each depth scan (A scan) with our OCT system. A new rigorous algorithm was then used to retrieve the calibrated polarization properties of the sample. This algorithm was validated with experimental data. The skin of a rat was imaged with this fiber-based system.

© 2003 Optical Society of America

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2002 (3)

2000 (2)

1999 (1)

1997 (1)

1987 (1)

Chen, Z.

Chipman, R. A.

de Boer, J. F.

Itoh, M.

Jiao, S.

Lu, S. Y.

Makita, S.

Milner, T. E.

Nelson, J. S.

Park, B. H.

Saxer, C. E.

Suto, Y.

van Gemert, M. J. C.

Wang, L.-H. V.

Yao, G.

Yasuno, Y.

Yatagai, T.

Zhao, Y.

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Figures (3)

Fig. 1
Fig. 1

Schematic of the fiber-based Mueller OCT system. SLDH and SLDV, superluminescent diodes, H and V polarized, respectively; PBS1 and PBS2, polarizing beam splitters; SF, spatial filter assembly; LP, linear polarizer; NBS, nonpolarizing beam splitter; M, mirror; SMFs, single-mode optical fibers; PDH and PDV, photodiodes for the H and V polarization components, respectively.

Fig. 2
Fig. 2

Round–trip phase retardation of a λ/4 plate calculated from the measured Jones matrix before and after cancellation of the polarization distortion caused by the sampling optical fiber. The phase retardation of the sampling fiber, which is by definition zero after cancellation, is shown as well.

Fig. 3
Fig. 3

M00 image of the Mueller matrix, the retardation images before and after cancellation of the polarization effect of the sampling fiber φsf2 and φs2 of the skin of a rat tail measured with the fiber-based Mueller OCT system. A histological image stained with hematoxylin and eosin is also shown for comparison. The M00 image is on a logarithmic scale, and the retardation images are on a linear scale. The height of each image is 1 mm. EP, epidermis; DP, dermal papilla; DJ, dermal–epidermal junction.

Equations (7)

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φs2=2 cos-112tr Js2+det Js2/det Js2tr Js2*trJs2*Js2+2det Js21/2,
Jfc1=cos γsin γ-sin γcos γ.