Abstract

A high-speed, all optical coherence tomography system was designed and constructed. This tomography system employs spectral interferometry and optical Fourier transformation to reduce the number of mechanical scanning dimensions required for multidimensional profilometry. The system also employs a time gate comprising a β-barium borate crystal driven by a femtosecond laser pulse to improve measurement time. This system has 43µm depth resolution and 150-fs temporal resolution and is capable of taking 1000 cross-sectional image frames per second.

© 2002 Optical Society of America

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2001 (1)

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

2000 (3)

R. Leitgeb, M. Wojtkowski, A. Kowalczyk, C. K. Hitzenberger, M. Sticker, and A. F. Fercher, Opt. Lett. 25, 820 (2000).
[CrossRef]

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

1999 (1)

J. K. Barton, J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, and A. J. Welch, Dermatology 198, 355 (1999).
[CrossRef]

1998 (4)

1997 (1)

D. Meshulach, D. Yelin, and Y. Silberberg, IEEE J. Quantum Electron. 33, 1969 (1997).
[CrossRef]

1992 (1)

1990 (1)

1972 (1)

Barton, J. K.

J. K. Barton, J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, and A. J. Welch, Dermatology 198, 355 (1999).
[CrossRef]

Bowe, B.

B. Bowe and V. Toal, Opt. Eng. 37, 1796 (1998).
[CrossRef]

Carvalho, L. A. V.

A. C. Oliveira, F. M. M. Yasuoka, J. B. Santos, L. A. V. Carvalho, and J. C. Castro, Rev. Sci. Instrum. 69, 1877 (1998).
[CrossRef]

Castro, J. C.

A. C. Oliveira, F. M. M. Yasuoka, J. B. Santos, L. A. V. Carvalho, and J. C. Castro, Rev. Sci. Instrum. 69, 1877 (1998).
[CrossRef]

Colston, B. W.

Da Silva, L. B.

Drexler, W.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

Everett, M. J.

Fercher, A. F.

Flournoy, P. A.

Fujimoto, J. G.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

Ghanta, R. K.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

Hitzenberger, C. K.

Itoh, M.

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

Y. Sutoh, Y. Yasuno, M. Itoh, M. Mori, and T. Yatagai, in Digest of Conference on Lasers and Electro-Optics (CLEO/Pacific Rim) (Optical Society of America, Washington, D.C., 2001), paper TuGl-2.

Izatt, J. A.

Kartner, F. X.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

Komori, K.

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Kowalczyk, A.

Kulkarni, M. D.

Lee, B. S.

Leitgeb, R.

McClure, R. W.

Meshulach, D.

D. Meshulach, D. Yelin, and Y. Silberberg, IEEE J. Quantum Electron. 33, 1969 (1997).
[CrossRef]

Morgner, U.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

Mori, M.

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

Y. Sutoh, Y. Yasuno, M. Itoh, M. Mori, and T. Yatagai, in Digest of Conference on Lasers and Electro-Optics (CLEO/Pacific Rim) (Optical Society of America, Washington, D.C., 2001), paper TuGl-2.

Nakama, M.

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

Nathel, H.

Oliveira, A. C.

A. C. Oliveira, F. M. M. Yasuoka, J. B. Santos, L. A. V. Carvalho, and J. C. Castro, Rev. Sci. Instrum. 69, 1877 (1998).
[CrossRef]

Otis, L. L.

Rollins, A. M.

Santos, J. B.

A. C. Oliveira, F. M. M. Yasuoka, J. B. Santos, L. A. V. Carvalho, and J. C. Castro, Rev. Sci. Instrum. 69, 1877 (1998).
[CrossRef]

Schuman, J. S.

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

Silberberg, Y.

D. Meshulach, D. Yelin, and Y. Silberberg, IEEE J. Quantum Electron. 33, 1969 (1997).
[CrossRef]

Sticker, M.

Strand, T. C.

Stroeve, P.

Sutoh, Y.

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Y. Sutoh, Y. Yasuno, M. Itoh, M. Mori, and T. Yatagai, in Digest of Conference on Lasers and Electro-Optics (CLEO/Pacific Rim) (Optical Society of America, Washington, D.C., 2001), paper TuGl-2.

Swanson, E. A.

Toal, V.

B. Bowe and V. Toal, Opt. Eng. 37, 1796 (1998).
[CrossRef]

Ung-arunyawee, R.

Watanabe, M.

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Welch, A. J.

J. K. Barton, J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, and A. J. Welch, Dermatology 198, 355 (1999).
[CrossRef]

Wojtkowski, M.

Wyntjes, G.

Yasuno, Y.

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

Y. Sutoh, Y. Yasuno, M. Itoh, M. Mori, and T. Yatagai, in Digest of Conference on Lasers and Electro-Optics (CLEO/Pacific Rim) (Optical Society of America, Washington, D.C., 2001), paper TuGl-2.

Yasuoka, F. M. M.

A. C. Oliveira, F. M. M. Yasuoka, J. B. Santos, L. A. V. Carvalho, and J. C. Castro, Rev. Sci. Instrum. 69, 1877 (1998).
[CrossRef]

Yatagai, T.

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Y. Sutoh, Y. Yasuno, M. Itoh, M. Mori, and T. Yatagai, in Digest of Conference on Lasers and Electro-Optics (CLEO/Pacific Rim) (Optical Society of America, Washington, D.C., 2001), paper TuGl-2.

Yazdanfar, S.

Yelin, D.

D. Meshulach, D. Yelin, and Y. Silberberg, IEEE J. Quantum Electron. 33, 1969 (1997).
[CrossRef]

Yoshikawa, N.

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Appl. Opt. (3)

Dermatology (1)

J. K. Barton, J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, and A. J. Welch, Dermatology 198, 355 (1999).
[CrossRef]

IEEE J. Quantum Electron. (1)

D. Meshulach, D. Yelin, and Y. Silberberg, IEEE J. Quantum Electron. 33, 1969 (1997).
[CrossRef]

Nature Med. (1)

W. Drexler, U. Morgner, R. K. Ghanta, F. X. Kartner, J. S. Schuman, and J. G. Fujimoto, Nature Med. 7, 502 (2001).
[CrossRef]

Opt. Commun. (2)

Y. Yasuno, Y. Sutoh, N. Yoshikawa, M. Itoh, M. Mori, K. Komori, M. Watanabe, and T. Yatagai, Opt. Commun. 177, 135 (2000).
[CrossRef]

Y. Yasuno, M. Nakama, Y. Sutoh, M. Itoh, M. Mori, and T. Yatagai, Opt. Commun. 186, 51 (2000).
[CrossRef]

Opt. Eng. (1)

B. Bowe and V. Toal, Opt. Eng. 37, 1796 (1998).
[CrossRef]

Opt. Express (1)

Opt. Lett. (2)

Rev. Sci. Instrum. (1)

A. C. Oliveira, F. M. M. Yasuoka, J. B. Santos, L. A. V. Carvalho, and J. C. Castro, Rev. Sci. Instrum. 69, 1877 (1998).
[CrossRef]

Other (1)

Y. Sutoh, Y. Yasuno, M. Itoh, M. Mori, and T. Yatagai, in Digest of Conference on Lasers and Electro-Optics (CLEO/Pacific Rim) (Optical Society of America, Washington, D.C., 2001), paper TuGl-2.

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Figures (3)

Fig. 1
Fig. 1

Schematic setup of the nonlinear spectral OCT system: BS, beam splitter; CC, corner cube; xCL, yCL, cylindrical lenses along the x and y axes, respectively; G, grating of 1800 line pairs/mm; M’s, mirrors. The light source is a regenerated Ti:sapphire pulse laser with 150-fs duration and 1-kHz repetition. The focal lengths of the cylindrical lenses are 60 mm for xCL1, 120 mm for xCL2, 150 mm for xCL3, and 200 mm for yCL.

Fig. 2
Fig. 2

Cross-section image taken with a CCD camera. The horizontal axis corresponds to the x axis on the CCD plane, which in turn corresponds to the z axis on the object. The vertical axis corresponds to the y axis of the CCD plane and also the y axis of the object. This image was taken with one shot of the probe pulse.

Fig. 3
Fig. 3

Three-dimensional surface of the sample whose cross-section image is shown in Fig. 2. We take 41 frames of the yz cross section and reconstruct this structure from them.

Equations (2)

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Ep2=E˜p1T2πxβλcf1exp-i2πβλcf1xt*Eˆp1Sxλcf1,
EoutEp1Tβλcf12πf2λh*EˆtrigSxf2λh,

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