Abstract

Acousto-optic (AO) imaging is a promising technique that is able to reveal optical properties in the millimeter range inside scattering media by tagging the photon paths with an ultrasonic beam. To increase both the contrast and the resolution of the AO images, we have explored the possibility of using the nonlinear response of the speckle modulation. Variation of the second-harmonic signal as the square of the ultrasonic amplitude has been found, and strong reduction of the tagged zone size has been demonstrated.

© 2002 Optical Society of America

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References

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2001

S. Lévêque-Fort, J. Selb, L. Pottier, and A. C. Boccara, Opt. Commun. 196, 127 (2001).
[CrossRef]

L. V. Wang, Phys. Rev. Lett. 87, 043903 (2001).
[CrossRef]

E. Granot, A. Lev, Z. Kotler, B. G. Sfev, and H. Taitelbaum, J. Opt. Soc. Am. A 18, 1962 (2001).
[CrossRef]

2000

1999

1997

1995

Boas, D. A.

J. Selb and D. A. Boas, paper presented at the OSA Biomedical Topical Meeting, Miami Beach, Fla., April 7–10, 2002.

Boccara, A. C.

S. Lévêque-Fort, J. Selb, L. Pottier, and A. C. Boccara, Opt. Commun. 196, 127 (2001).
[CrossRef]

S. Lévêque, A. C. Boccara, M. Lebec, and H. Saint-Jalmes, Opt. Lett. 24, 181 (1999).
[CrossRef]

Genack, A. Z.

Granot, E.

Hisaka, M.

M. Hisaka, T. Sugiura, and S. Kawata, paper presented at the Forum on Microscopy 2000, Shirahama, Japan, April 9–13, 2000.

Jacques, S. L.

Jiao, S.

Kawata, S.

M. Hisaka, T. Sugiura, and S. Kawata, paper presented at the Forum on Microscopy 2000, Shirahama, Japan, April 9–13, 2000.

Kempe, M.

Kotler, Z.

Larionov, M.

Lebec, M.

Leutz, W.

W. Leutz and G. Maret, Physica B 204, 14 (1995).
[CrossRef]

Lev, A.

Lévêque, S.

Lévêque-Fort, S.

S. Lévêque-Fort, J. Selb, L. Pottier, and A. C. Boccara, Opt. Commun. 196, 127 (2001).
[CrossRef]

S. Lévêque-Fort, Appl. Opt. 40, 1029 (2000).
[CrossRef]

Maret, G.

W. Leutz and G. Maret, Physica B 204, 14 (1995).
[CrossRef]

Pottier, L.

S. Lévêque-Fort, J. Selb, L. Pottier, and A. C. Boccara, Opt. Commun. 196, 127 (2001).
[CrossRef]

Saint-Jalmes, H.

Selb, J.

S. Lévêque-Fort, J. Selb, L. Pottier, and A. C. Boccara, Opt. Commun. 196, 127 (2001).
[CrossRef]

J. Selb and D. A. Boas, paper presented at the OSA Biomedical Topical Meeting, Miami Beach, Fla., April 7–10, 2002.

Sfev, B. G.

Sugiura, T.

M. Hisaka, T. Sugiura, and S. Kawata, paper presented at the Forum on Microscopy 2000, Shirahama, Japan, April 9–13, 2000.

Taitelbaum, H.

Wang, L.

Wang, L. V.

Yao, G.

Zaslavsky, D.

Zhao, X.

Appl. Opt.

J. Opt. Soc. Am. A

Opt. Commun.

S. Lévêque-Fort, J. Selb, L. Pottier, and A. C. Boccara, Opt. Commun. 196, 127 (2001).
[CrossRef]

Opt. Lett.

Phys. Rev. Lett.

L. V. Wang, Phys. Rev. Lett. 87, 043903 (2001).
[CrossRef]

Physica B

W. Leutz and G. Maret, Physica B 204, 14 (1995).
[CrossRef]

Other

J. Selb and D. A. Boas, paper presented at the OSA Biomedical Topical Meeting, Miami Beach, Fla., April 7–10, 2002.

M. Hisaka, T. Sugiura, and S. Kawata, paper presented at the Forum on Microscopy 2000, Shirahama, Japan, April 9–13, 2000.

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Figures (4)

Fig. 1
Fig. 1

Dependence of the normalized AO signal on the voltage applied to the transducer at the fundamental frequency (f=3 MHz; left) and the second-harmonic frequency (2f=6 MHz; right).

Fig. 2
Fig. 2

Maps of the fundamental (3 MHz; top) and the second-harmonic (6 MHz; bottom) components of the acoustic pressure emitted by the ultrasonic transducer. The gray scale indicates the value of the negative peak pressure. Since the measurement was performed in water, the pressure does not undergo the attenuation of acoustic waves in tissues (1.8 dB/cm at 3 MHz).

Fig. 3
Fig. 3

Spatial distribution of the modulated light on the exit face of the sample, showing the modulations at frequencies f (left) and 2f (right), normalized pixel to pixel by the distribution of dc-scattered light. Each side of each picture corresponds to a length of approximately 2 cm.

Fig. 4
Fig. 4

AO profiles obtained at frequencies f and 2f on an absorbing inclusion. The scales for the two curves are different, but the baselines coincide.

Equations (3)

Equations on this page are rendered with MathJax. Learn more.

S0-S22+S1-S321/2=I1N2πf,
S0-S1+S2-S3=I2Nf2πsin φ2,
S0-S1+S2-S3=I2Nf4π2.

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