Abstract

We report a method for extracting the birefringence properties of biological samples with micrometer-scale resolution in three dimensions, using a new form of polarization-sensitive optical coherence tomography. The method measures net retardance, net fast axis, and total reflectivity as a function of depth into the sample. Polarization sensing is accomplished by illumination of the sample with at least three separate polarization states during consecutive acquisitions of the same pixel, A scan, or B scan. The method can be implemented by use of non-polarization-maintaining fiber and a single detector. In a calibration test of the system, net retardance was measured with an average error of 7.5° (standard deviation 2.2°) over the retardance range 0° to 180°, and a fast axis with average error of 4.8° over the range 0° to 180°.

© 2001 Optical Society of America

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1999

1998

1997

1992

Chen, Z.

Colston, B. W.

Da Silva, L. B.

De Boer, J.

de Boer, J. F.

Everett, M. J.

Fujimoto, J. G.

Hee, M. R.

Huang, D.

Izatt, J. A.

Kulkarni, M. D.

Maitland, D. J.

Malekafzali, A.

Milner, T. E.

Nelson, J. S.

Park, B. H.

Rollins, A. M.

Saxer, C. E.

Schoenenberger, K.

Srinivas, S.

Swanson, E. A.

Ung-Arunyawee, R.

van Gemert, M. J. C.

Zhao, Y.

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