Abstract

A combination of light and focused ultrasound waves provides a unique way to obtain directly three-dimensional absorption data in a turbid medium. We present the combination of an ultrasound wave and light in which both the input and the output optodes are on the same side of the sample (reflectance geometry). This technique permits local detection in depth of the presence of a purely absorbing object, without further mathematical processing. It is a promising technique for medical imaging and monitoring of tissues.

© 2000 Optical Society of America

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References

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1999

M. A. Franceschini, E. Gratton, and S. Fantini, Opt. Lett. 24, 12 (1999).
[CrossRef]

S. Leveque, A. C. Boccara, M. Lebec, and H. Saint-Jalmes, Opt. Lett. 24, 181 (1999).
[CrossRef]

1998

1997

1995

B. Chance and A. Yodh, Phys. Today 48(3), 34 (1995).

W. Leutz and G. Maret, Physica B 204, 14 (1995).
[CrossRef]

L. Wang, S. L. Jacques, and X. Zhao, Opt. Lett. 20, 629 (1995).
[CrossRef] [PubMed]

1994

1993

P. A. Marks, H. W. Tomlinson, and G. W. Breksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

D. A. Benaron and D. K. Stevenson, Science 256, 1463 (1993).
[CrossRef]

1992

1990

1977

F. F. Jobsis, Science 198, 1264 (1977).
[CrossRef]

Andersson-Engels, S. R.

Benaron, D. A.

D. A. Benaron and D. K. Stevenson, Science 256, 1463 (1993).
[CrossRef]

Berg, R.

Boccara, A. C.

Breksby, G. W.

P. A. Marks, H. W. Tomlinson, and G. W. Breksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

Chance, B.

B. Chance and A. Yodh, Phys. Today 48(3), 34 (1995).

Delpy, D. T.

Dolfi, D.

D. Dolfi and F. Micheron, “Imaging process and system for transillumination with photon frequency marking,” International Patent WO 89/00278 (January 12, 1989).

Fantini, S.

M. A. Franceschini, E. Gratton, and S. Fantini, Opt. Lett. 24, 12 (1999).
[CrossRef]

Fishkin, J. B.

Franceschini, M. A.

M. A. Franceschini, E. Gratton, and S. Fantini, Opt. Lett. 24, 12 (1999).
[CrossRef]

Genack, A. Z.

Gratton, E.

M. A. Franceschini, E. Gratton, and S. Fantini, Opt. Lett. 24, 12 (1999).
[CrossRef]

J. B. Fishkin and E. Gratton, J. Opt. Soc. Am. A 10, 127 (1992).
[CrossRef]

Hebden, J. C.

Jacques, S. L.

Jarlman, O.

Jobsis, F. F.

F. F. Jobsis, Science 198, 1264 (1977).
[CrossRef]

Kempe, M.

Ku, G.

Larionov, M.

Lebec, M.

Leutz, W.

W. Leutz and G. Maret, Physica B 204, 14 (1995).
[CrossRef]

Leveque, S.

Maret, G.

W. Leutz and G. Maret, Physica B 204, 14 (1995).
[CrossRef]

Marks, P. A.

P. A. Marks, H. W. Tomlinson, and G. W. Breksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

Micheron, F.

D. Dolfi and F. Micheron, “Imaging process and system for transillumination with photon frequency marking,” International Patent WO 89/00278 (January 12, 1989).

Saint-Jalmes, H.

Stevenson, D. K.

D. A. Benaron and D. K. Stevenson, Science 256, 1463 (1993).
[CrossRef]

Svanberg, S.

Tiemann, J.

H. W. Tomlinson and J. Tiemann, “Light imaging in a scattering medium, using ultrasonic probing and speckle image differencing,” U.S. patent 5,212,667 (May 18, 1993).

Tomlinson, H. W.

P. A. Marks, H. W. Tomlinson, and G. W. Breksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

H. W. Tomlinson and J. Tiemann, “Light imaging in a scattering medium, using ultrasonic probing and speckle image differencing,” U.S. patent 5,212,667 (May 18, 1993).

Wang, L.

Wang, L. V.

Yodh, A.

B. Chance and A. Yodh, Phys. Today 48(3), 34 (1995).

Zaslavski, D.

Zhao, X.

J. Opt. Soc. Am. A

Opt. Lett.

Phys. Today

B. Chance and A. Yodh, Phys. Today 48(3), 34 (1995).

Physica B

W. Leutz and G. Maret, Physica B 204, 14 (1995).
[CrossRef]

Proc. SPIE

P. A. Marks, H. W. Tomlinson, and G. W. Breksby, Proc. SPIE 1888, 500 (1993).
[CrossRef]

Science

F. F. Jobsis, Science 198, 1264 (1977).
[CrossRef]

D. A. Benaron and D. K. Stevenson, Science 256, 1463 (1993).
[CrossRef]

Other

D. Dolfi and F. Micheron, “Imaging process and system for transillumination with photon frequency marking,” International Patent WO 89/00278 (January 12, 1989).

H. W. Tomlinson and J. Tiemann, “Light imaging in a scattering medium, using ultrasonic probing and speckle image differencing,” U.S. patent 5,212,667 (May 18, 1993).

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Figures (3)

Fig. 1
Fig. 1

Experimental setup for the detection of ultrasound modulated signals in a reflection geometry. The transducer and the laser are kept fixed while the phantom is scanned. PMT, photomultiplier tube.

Fig. 2
Fig. 2

Ultrasound transducer-and-fibers configuration on the phantom: (a) from above, (b) section of the phantom at the place where the absorptive object is present.

Fig. 3
Fig. 3

Ultrasound scans without (squares) and with (circles) an absorbing object. Note that, without the ultrasound, the object is not visible at all, even with strong white-light illumination.

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