Abstract

We report on a modification of optical coherence tomography (OCT) that allows one to measure small phase differences between beams traversing adjacent areas of a specimen. The sample beam of a polarization-sensitive low-coherence interferometer is split by a Wollaston prism into two components that traverse the object along closely spaced paths. After reflection at the various sample surfaces, the beams are recombined at the Wollaston prism. Any phase difference encountered between the two beams is converted into a change of polarization state of the recombined beam. This change is measured, and the resulting signals are converted to differential phase-contrast OCT images. The first images obtained from simple test objects allowed us to determine path-difference gradients with a resolution of the order of 5×10-5.

© 1999 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
    [CrossRef] [PubMed]
  2. E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Lett. 18, 1864 (1993).
    [CrossRef] [PubMed]
  3. J. A. Izatt, M. R. Hee, G. M. Owen, E. A. Swanson, and J. G. Fujimoto, Opt. Lett. 19, 590 (1994).
    [CrossRef] [PubMed]
  4. J. M. Schmitt, S. L. Lee, and K. M. Yung, Opt. Commun. 142, 203 (1997).
    [CrossRef]
  5. E. Beaurepaire, A. C. Boccara, M. Lebec, L. Blanchot, and H. Saint-Jalmes, Opt. Lett. 23, 244 (1998).
    [CrossRef]
  6. A. Baumgartner, C. K. Hitzenberger, H. Sattmann, W. Drexler, and A. F. Fercher, J. Biomed. Opt. 3, 45 (1998).
    [CrossRef] [PubMed]
  7. A. F. Fercher, J. Biomed. Opt. 1, 157 (1996).
    [CrossRef] [PubMed]
  8. M. R. Hee, D. Huang, E. A. Swanson, and J. G. Fujimoto, J. Opt. Soc. Am. B 9, 903 (1992).
    [CrossRef]
  9. J. F. de Boer, T. E. Milner, M. J. C. van Gemert, and J. S. Nelson, Opt. Lett. 22, 934 (1997).
    [CrossRef] [PubMed]
  10. M. J. Everett, K. Schoenenberger, B. W. Colston, and L. B. Da Silva, Opt. Lett. 23, 228 (1998).
    [CrossRef]

1998 (3)

1997 (2)

1996 (1)

A. F. Fercher, J. Biomed. Opt. 1, 157 (1996).
[CrossRef] [PubMed]

1994 (1)

1993 (1)

1992 (1)

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Baumgartner, A.

A. Baumgartner, C. K. Hitzenberger, H. Sattmann, W. Drexler, and A. F. Fercher, J. Biomed. Opt. 3, 45 (1998).
[CrossRef] [PubMed]

Beaurepaire, E.

Blanchot, L.

Boccara, A. C.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Colston, B. W.

Da Silva, L. B.

de Boer, J. F.

Drexler, W.

A. Baumgartner, C. K. Hitzenberger, H. Sattmann, W. Drexler, and A. F. Fercher, J. Biomed. Opt. 3, 45 (1998).
[CrossRef] [PubMed]

Everett, M. J.

Fercher, A. F.

A. Baumgartner, C. K. Hitzenberger, H. Sattmann, W. Drexler, and A. F. Fercher, J. Biomed. Opt. 3, 45 (1998).
[CrossRef] [PubMed]

A. F. Fercher, J. Biomed. Opt. 1, 157 (1996).
[CrossRef] [PubMed]

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Fujimoto, J. G.

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Hee, M. R.

Hitzenberger, C. K.

A. Baumgartner, C. K. Hitzenberger, H. Sattmann, W. Drexler, and A. F. Fercher, J. Biomed. Opt. 3, 45 (1998).
[CrossRef] [PubMed]

Huang, D.

Izatt, J. A.

Lebec, M.

Lee, S. L.

J. M. Schmitt, S. L. Lee, and K. M. Yung, Opt. Commun. 142, 203 (1997).
[CrossRef]

Lin, C. P.

E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Lett. 18, 1864 (1993).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Milner, T. E.

Nelson, J. S.

Owen, G. M.

Puliafito, C. A.

E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Lett. 18, 1864 (1993).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Saint-Jalmes, H.

Sattmann, H.

A. Baumgartner, C. K. Hitzenberger, H. Sattmann, W. Drexler, and A. F. Fercher, J. Biomed. Opt. 3, 45 (1998).
[CrossRef] [PubMed]

Schmitt, J. M.

J. M. Schmitt, S. L. Lee, and K. M. Yung, Opt. Commun. 142, 203 (1997).
[CrossRef]

Schoenenberger, K.

Schuman, J. S.

E. A. Swanson, J. A. Izatt, M. R. Hee, D. Huang, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Lett. 18, 1864 (1993).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, Science 254, 1178 (1991).
[CrossRef] [PubMed]

Swanson, E. A.

van Gemert, M. J. C.

Yung, K. M.

J. M. Schmitt, S. L. Lee, and K. M. Yung, Opt. Commun. 142, 203 (1997).
[CrossRef]

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (3)

Fig. 1
Fig. 1

Schematic of the OCT setup for differential phase-contrast tomography. See text for definitions.

Fig. 2
Fig. 2

OCT images of a test object consisting of a microscope carrier glass, a single-component glue, and a cover glass. For easy identification the interfaces are numbered (1) to (4). Illumination is from the bottom of the object. (a) Schematic of the test object (not drawn to scale), (b) in-tensity image, (c) phase image. The dimensions of the tomograms are 3 mmhorizontal×2.5 mm [vertical (optical distance)].

Fig. 3
Fig. 3

OCT images of a test object consisting of a microscope carrier glass, a two-component glue, and a cover glass. Illumination is from the bottom of the object. (a) Intensity image, (b) phase image. The dimensions of the tomograms are 3 mm horizontal×2.5 mm [vertical (optical distance)].

Metrics