Abstract

We report an original two-dimensional time-resolved direct imaging method for transillumination optical tomography that combines the time-gating and forward phase-conjugation properties of type II degenerate parametric amplification. An object with subcentimeter resolution embedded in 4-cm-thick chicken breast tissue was imaged with a signal-to-noise ratio of 2.

© 1999 Optical Society of America

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1998 (4)

1997 (3)

G. Le Tolguenec, F. Devaux, and E. Lantz, J. Opt. (Paris) 28, 214 (1997).
[CrossRef]

G. Le Tolguenec, E. Lantz, and F. Devaux, Appl. Opt. 36, 8292 (1997).
[CrossRef]

E. Cuche, P. Poscio, and C. Depeursinge, J. Opt. (Paris) 28, 260 (1997).
[CrossRef]

1996 (3)

F. Devaux, E. Lantz, and H. Maillotte, J. Nonlin. Opt. Phys. Mater. 5, 413 (1996).
[CrossRef]

E. B. De Haller, J. Biomed. Opt. 1, 7 (1996).
[CrossRef] [PubMed]

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

1995 (2)

1994 (1)

1993 (3)

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

M. R. Hee, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, Opt. Lett. 18, 1107 (1993).
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B. B. Das, K. M. Yoo, and R. R. Alfano, Opt. Lett. 18, 1092 (1993).
[CrossRef]

1991 (1)

Akatsuka, T.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Alfano, R. R.

Barry, N. P.

Boppart, S. A.

Bouma, B.

Brezinski, M. E.

Chan, K.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Cuche, E.

E. Cuche, P. Poscio, and C. Depeursinge, J. Opt. (Paris) 28, 260 (1997).
[CrossRef]

Das, B. B.

De Haller, E. B.

E. B. De Haller, J. Biomed. Opt. 1, 7 (1996).
[CrossRef] [PubMed]

Depeursinge, C.

E. Cuche, P. Poscio, and C. Depeursinge, J. Opt. (Paris) 28, 260 (1997).
[CrossRef]

Devaraj, B.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Devaux, F.

F. Devaux, G. Le Tolguenec, and E. Lantz, Opt. Commun. 147, 309 (1998).
[CrossRef]

F. Devaux, E. Guiot, and E. Lantz, Opt. Lett. 23, 1597 (1998).
[CrossRef]

G. Le Tolguenec, E. Lantz, and F. Devaux, Appl. Opt. 36, 8292 (1997).
[CrossRef]

G. Le Tolguenec, F. Devaux, and E. Lantz, J. Opt. (Paris) 28, 214 (1997).
[CrossRef]

F. Devaux, E. Lantz, and H. Maillotte, J. Nonlin. Opt. Phys. Mater. 5, 413 (1996).
[CrossRef]

Dilworth, D.

Duncan, M. D.

Eick, A. A.

French, P. M. W.

Freyer, J. P.

Fujimoto, J. G.

Guiot, E.

Hee, M. H.

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

Hee, M. R.

Hielscher, A. H.

Huang, D.

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

Hyde, S. C. W.

Inaba, H.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Izatt, J. A.

M. R. Hee, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, Opt. Lett. 18, 1107 (1993).
[CrossRef]

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

Johnson, T. M.

Jones, R.

Kobayashi, M.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Kwolek, K. W.

Lantz, E.

F. Devaux, E. Guiot, and E. Lantz, Opt. Lett. 23, 1597 (1998).
[CrossRef]

F. Devaux, G. Le Tolguenec, and E. Lantz, Opt. Commun. 147, 309 (1998).
[CrossRef]

G. Le Tolguenec, F. Devaux, and E. Lantz, J. Opt. (Paris) 28, 214 (1997).
[CrossRef]

G. Le Tolguenec, E. Lantz, and F. Devaux, Appl. Opt. 36, 8292 (1997).
[CrossRef]

F. Devaux, E. Lantz, and H. Maillotte, J. Nonlin. Opt. Phys. Mater. 5, 413 (1996).
[CrossRef]

Le Tolguenec, G.

F. Devaux, G. Le Tolguenec, and E. Lantz, Opt. Commun. 147, 309 (1998).
[CrossRef]

G. Le Tolguenec, E. Lantz, and F. Devaux, Appl. Opt. 36, 8292 (1997).
[CrossRef]

G. Le Tolguenec, F. Devaux, and E. Lantz, J. Opt. (Paris) 28, 214 (1997).
[CrossRef]

Lin, C. P.

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

Mahon, R.

Maillotte, H.

F. Devaux, E. Lantz, and H. Maillotte, J. Nonlin. Opt. Phys. Mater. 5, 413 (1996).
[CrossRef]

Melloch, M. R.

Moon, J. A.

Mourant, J. P.

Naulleau, P.

Nolte, D. D.

Poscio, P.

E. Cuche, P. Poscio, and C. Depeursinge, J. Opt. (Paris) 28, 260 (1997).
[CrossRef]

Puliafito, C. A.

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

Reintjes, R.

Schuman, J. S.

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

Shen, D.

Shimizu, K.

K. Shimizu and K. Yamamoto, in Advances in Optical Imaging and Photon Migration, Vol. 2 of OSA Trends in Optics and Photonics Series (Optical Society of America, Washington, D.C., 1996), pp. 348–352.

Swanson, E. A.

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

M. R. Hee, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, Opt. Lett. 18, 1107 (1993).
[CrossRef]

Takeda, M.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Tearney, G. J.

Usa, M.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Watanabe, Y.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Xing, Q.

Yamamoto, K.

K. Shimizu and K. Yamamoto, in Advances in Optical Imaging and Photon Migration, Vol. 2 of OSA Trends in Optics and Photonics Series (Optical Society of America, Washington, D.C., 1996), pp. 348–352.

Yameda, M.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Yoo, K. M.

Yuasa, T.

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

Appl. Opt. (2)

Appl. Phys. Lett. (1)

B. Devaraj, M. Takeda, M. Kobayashi, M. Usa, K. Chan, Y. Watanabe, T. Yuasa, T. Akatsuka, M. Yameda, and H. Inaba, Appl. Phys. Lett. 24, 3671 (1996).
[CrossRef]

J. Biomed. Opt. (1)

E. B. De Haller, J. Biomed. Opt. 1, 7 (1996).
[CrossRef] [PubMed]

J. Nonlin. Opt. Phys. Mater. (1)

F. Devaux, E. Lantz, and H. Maillotte, J. Nonlin. Opt. Phys. Mater. 5, 413 (1996).
[CrossRef]

J. Opt. (Paris) (2)

G. Le Tolguenec, F. Devaux, and E. Lantz, J. Opt. (Paris) 28, 214 (1997).
[CrossRef]

E. Cuche, P. Poscio, and C. Depeursinge, J. Opt. (Paris) 28, 260 (1997).
[CrossRef]

Opt. Commun. (1)

F. Devaux, G. Le Tolguenec, and E. Lantz, Opt. Commun. 147, 309 (1998).
[CrossRef]

Opt. Lett. (8)

Opt. Photon. News (1)

J. A. Izatt, M. H. Hee, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, C. A. Puliafito, and J. G. Fujimoto, Opt. Photon. News 4(10), 14 (1993).
[CrossRef]

Other (2)

K. Shimizu and K. Yamamoto, in Advances in Optical Imaging and Photon Migration, Vol. 2 of OSA Trends in Optics and Photonics Series (Optical Society of America, Washington, D.C., 1996), pp. 348–352.

International Electrotechnical Commission, “Radiation safety of laser products, equipment classification, requirements and user’s guide,” (International Electrotechnical Commission, Geneva, Switzerland, 1984).

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Figures (3)

Fig. 1
Fig. 1

Experimental setup: Σo, object plane; Σv, virtual object plane; Σc, phase-conjugated image plane; P1P3, Glan–Taylor polarizers.

Fig. 2
Fig. 2

a, Amplified image of the strips without biological tissue; b, c, d, e, f, amplified images through 4-cm-thick chicken breast tissue. The delays are, respectively, -16, 0, 33, 58, and 158 ps. In b–d the strips are resolved; in c the best SNR is 2; in e and f the strips are no longer resolved.

Fig. 3
Fig. 3

Time-resolved profiles of idler intensity with and without biological tissue with respect to the pump delay. * and + correspond to the experimental measures; curves are an aid to the eye.

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