Abstract

Phase-contrast microscopy shows that the structure of the refractive-index inhomogeneities in a variety of mammalian tissues resembles that of frozen turbulence. Viewed over a range of scales, the spectrum of index variations exhibits a power-law behavior for spatial frequencies spanning at least a decade (0.5–5 μm−1) and has an outer scale in the range of 4–10 μm, above which correlations are no longer seen. The observed structure function fits the classical Kolmogorov model of turbulence. These observations are fundamental to understanding light propagation in tissue and may provide clues about how tissues develop and organize.

© 1996 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Experimental measurement of the refractive index of biological tissues by total internal reflection

Jiancheng Lai, Zhenhua Li, Chunyong Wang, and Anzhi He
Appl. Opt. 44(10) 1845-1849 (2005)

Experimental estimation of the spatial statistics of turbulence-induced index of refraction fluctuations in the upper atmosphere

Jeffrey T. Beyer, Michael C. Roggemann, L. John Otten, Timothy J. Schulz, Timothy C. Havens, and Wade W. Brown
Appl. Opt. 42(6) 908-921 (2003)

Selective delivery of laser energy to biological tissue based on refractive-index differences

Yacov Domankevitz, Jerry Waldman, Charles P. Lin, and R. Rox Anderson
Opt. Lett. 25(15) 1104-1106 (2000)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (3)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription