Abstract

We describe a novel frequency-domain photon migration instrument employing direct diode laser modulation and avalanche photodiode detection, which is capable of noninvasively determinating the optical properties of biological tissues in near real time. An infinite medium diffusion model was used to extract absorption and transport scattering coefficients from 300-kHz to 800-MHz photon-density wave phase data. Optical properties measured in tissue-simulating solutions at 670 nm agreed to within 10% of those expected.

© 1994 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Frequency-domain photon migration measurements of normal and malignant tissue optical properties in a human subject

Joshua B. Fishkin, Olivier Coquoz, Eric R. Anderson, Matthew Brenner, and Bruce J. Tromberg
Appl. Opt. 36(1) 10-20 (1997)

Localization of absorbers in scattering media by use of frequency-domain measurements of time-dependent photon migration

E. M. Sevick, J. K. Frisoli, C. L. Burch, and J. R. Lakowicz
Appl. Opt. 33(16) 3562-3570 (1994)

Optical property measurements of turbid media in a small-volume cuvette with frequency-domain photon migration

Olivier Coquoz, Lars O. Svaasand, and Bruce J. Tromberg
Appl. Opt. 40(34) 6281-6291 (2001)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Tables (1)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (1)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription