Abstract

The intensity of the early-arriving snake portion of 100-fs ultrashort laser pulses transmitted through biological tissue of increasing thickness was measured by a streak camera. The snake photon intensity within the first arrival time interval. Δt was found to decrease exponentially with tissue thickness (z) as It) = I0A exp[−bt)z/lt], where I0 is the incident laser pulse intensity, lt is the transport mean free path of the medium, and the parameters b and A depend on the time interval Δt. This result shows that the intensity of snake photons decays significantly more slowly than that of ballistic photons as tissue thickness increases.

© 1994 Optical Society of America

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References

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    [CrossRef] [PubMed]
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    [CrossRef] [PubMed]
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1993 (2)

1991 (2)

1990 (1)

Alfano, R. R.

Chen, H.

Chen, Y.

Das, B. B.

Dilworth, D.

Fujimoto, J. G.

Fulton, R. C.

M. Lax, V. Nayaramamurti, R. C. Fulton, in Proceedings of the Symposium on Laser Optics of Condensed Matter, Leningrad, June 1987, J. L. Birman, H. Z. Cummins, A. A. Kaplyanskii, eds. (Plenum, New York, 1987), pp. 229–235.

Hee, M. R.

Ho, P. P.

L. M. Wang, P. P. Ho, C. Liu, G. Zhang, R. R. Alfano, Science 253, 769 (1991).
[CrossRef] [PubMed]

Izatt, J. A.

Lax, M.

M. Lax, V. Nayaramamurti, R. C. Fulton, in Proceedings of the Symposium on Laser Optics of Condensed Matter, Leningrad, June 1987, J. L. Birman, H. Z. Cummins, A. A. Kaplyanskii, eds. (Plenum, New York, 1987), pp. 229–235.

Leith, E.

Liu, C.

L. M. Wang, P. P. Ho, C. Liu, G. Zhang, R. R. Alfano, Science 253, 769 (1991).
[CrossRef] [PubMed]

Lopez, J.

Nayaramamurti, V.

M. Lax, V. Nayaramamurti, R. C. Fulton, in Proceedings of the Symposium on Laser Optics of Condensed Matter, Leningrad, June 1987, J. L. Birman, H. Z. Cummins, A. A. Kaplyanskii, eds. (Plenum, New York, 1987), pp. 229–235.

Swanson, E. A.

Valdmanis, J.

Wang, L. M.

L. M. Wang, P. P. Ho, C. Liu, G. Zhang, R. R. Alfano, Science 253, 769 (1991).
[CrossRef] [PubMed]

Yoo, K. M.

Zhang, G.

L. M. Wang, P. P. Ho, C. Liu, G. Zhang, R. R. Alfano, Science 253, 769 (1991).
[CrossRef] [PubMed]

Opt. Lett. (4)

Science (1)

L. M. Wang, P. P. Ho, C. Liu, G. Zhang, R. R. Alfano, Science 253, 769 (1991).
[CrossRef] [PubMed]

Other (1)

M. Lax, V. Nayaramamurti, R. C. Fulton, in Proceedings of the Symposium on Laser Optics of Condensed Matter, Leningrad, June 1987, J. L. Birman, H. Z. Cummins, A. A. Kaplyanskii, eds. (Plenum, New York, 1987), pp. 229–235.

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Figures (5)

Fig. 1
Fig. 1

Schematic diagram of the experimental arrangement. SIT, silicon intensified target.

Fig. 2
Fig. 2

Normalized temporal profiles of 100-fs ultra-fast laser pulses transmitting through uncompressed chicken breast tissue of different thicknesses. Solid curves, experiment; dashed curves, theory (lt = 2.4 mm, la = 53 mm).

Fig. 3
Fig. 3

Integrated intensities of transmitted photons at various time intervals Δt through chicken breast tissues as a function of the tissue thickness.

Fig. 4
Fig. 4

Integrated intensities of transmitted photons at various time intervals Δt as a function of the parameter z/lt. Solid curves, diffusion theory [Eqs. (1) and (2)]; dashed curves, Eq. (3). z = 60 mm, la = 60 mm, and Δt = 10, 20, 50, 100, 200, 500, 1000, and 2000 ps (from the bottom curve up).

Fig. 5
Fig. 5

Plot of the exponent factor b versus the time interval Δt for various cases (see text for parameters).

Equations (3)

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I z ( t ) = F D π z 2 [ 1 - exp ( - a 2 / 4 D t ) ] m = 1 m ( π z d ) 2 × sin m π z d exp [ - D t ( m π d ) 2 ] exp ( - ν t l a ) ,
I ( Δ t ) = t b t b + Δ t I z ( t ) d t ,
I ( Δ t ) = I 0 A exp [ - b ( Δ t ) z / l t ] ,

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