Abstract

Recently we demonstrated a biosensor based on a two-dimensional photonic crystal microcavity for detection of proteins. We present a theoretical and experimental study of a modified structure for single particle detection. With an active sensing volume of 0.15μm3, the device is capable of detecting 1fg of matter. Its performance is tested with latex spheres with sizes that fall in the size range of a variety of viruses.

© 2007 Optical Society of America

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