Optical coherence microscopy (OCM) is demonstrated with a high-speed, broadband, reflective-grating phase modulator and a femtosecond laser. The novel system design permits high-resolution OCM imaging in a new operating regime in which a short coherence gate is used to relax the requirement for high-numerical-aperture confocal axial sectioning. In vivo cellular imaging is demonstrated in the Xenopus laevis tadpole and in human skin with a coherence gate and a confocal gate. The ability to achieve cellular imaging with a lower numerical aperture should facilitate the development of miniaturized probes for in vivo imaging applications.
© 2003 Optical Society of AmericaFull Article | PDF Article
Joseph A. Izatt, Eric A. Swanson, James G. Fujimoto, Michael R. Hee, and Gabrielle M. Owen
Opt. Lett. 19(8) 590-592 (1994)
Faming Xu, Haridas E. Pudavar, Paras N. Prasad, and David Dickensheets
Opt. Lett. 24(24) 1808-1810 (1999)
R. Huber, M. Wojtkowski, J. G. Fujimoto, J. Y. Jiang, and A. E. Cable
Opt. Express 13(26) 10523-10538 (2005)