Abstract

A grating-coupled planar optical waveguide sensor is presented for sensing of bacteria by evanescent waves. The waveguide design results in increased depth of penetration into the sample volume, which makes it suitable for detecting micrometer-sized biological objects. We tested the sensor’s performance by monitoring the adhesion of Escherichia coli K12 cells to the sensor surface.

© 2003 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. P. Feng, in Bacterial Analytical Manual, G. J. Jackson, R. I. Merker, and R. Bandler (U.S. Food and Drug Administration, Washington, D.C., 2001), App. 1; http://vm.cfsan.fda.gov/~ebam/bam-al.html.
  2. P. M. Fratamico, T. P. Strobaugh, M. B. Medina, and A. G. Gehring, Biotechnol. Tech. 12, 571 (1998).
    [CrossRef]
  3. H. J. Watts, C. R. Lowe, and D. V. Pollard-Knight, Anal. Chem. 66, 2465 (1994).
    [CrossRef] [PubMed]
  4. A. N. Sloper, J. K. Deacon, and M. T. Falnagan, Sens. Actuators B 1, 589 (1990).
    [CrossRef]
  5. W. Lukosz, Sens. Actuators B 29, 37 (1995).
    [CrossRef]
  6. K. H. Seo, R. E. Brackett, N. F. Hartman, and D. P. Campbell, J. Food Protection 62, 431 (1999).
  7. B. A. Forbes, D. F. Sahm, and A. S. Weissfeld, Diagnostic Microbiology (Mosby, St. Louis, Mo., 1998), Chap. 15.
  8. R. Horváth, L. R. Lindvold, and N. B. Larsen, Appl. Phys. B 74, 383 (2002).
    [CrossRef]
  9. R. Horváth, H. C. Pedersen, and N. B. Larsen, Appl. Phys. Lett. 81, 2166 (2002).
    [CrossRef]
  10. Y. H. An and R. J. Friedman, J. Biomed. Mater. Res. 43, 338 (1998).
    [CrossRef] [PubMed]
  11. P. K. Tien, Rev. Mod. Phys. 49, 361 (1977).
    [CrossRef]
  12. K. Tiefenthaler and W. Lukosz, J. Opt. Soc. Am. B 6, 209 (1989).
    [CrossRef]
  13. Y. Ren, Opt. Mater. 19, 443 (2002).
    [CrossRef]

2002 (3)

R. Horváth, L. R. Lindvold, and N. B. Larsen, Appl. Phys. B 74, 383 (2002).
[CrossRef]

R. Horváth, H. C. Pedersen, and N. B. Larsen, Appl. Phys. Lett. 81, 2166 (2002).
[CrossRef]

Y. Ren, Opt. Mater. 19, 443 (2002).
[CrossRef]

1999 (1)

K. H. Seo, R. E. Brackett, N. F. Hartman, and D. P. Campbell, J. Food Protection 62, 431 (1999).

1998 (2)

P. M. Fratamico, T. P. Strobaugh, M. B. Medina, and A. G. Gehring, Biotechnol. Tech. 12, 571 (1998).
[CrossRef]

Y. H. An and R. J. Friedman, J. Biomed. Mater. Res. 43, 338 (1998).
[CrossRef] [PubMed]

1995 (1)

W. Lukosz, Sens. Actuators B 29, 37 (1995).
[CrossRef]

1994 (1)

H. J. Watts, C. R. Lowe, and D. V. Pollard-Knight, Anal. Chem. 66, 2465 (1994).
[CrossRef] [PubMed]

1990 (1)

A. N. Sloper, J. K. Deacon, and M. T. Falnagan, Sens. Actuators B 1, 589 (1990).
[CrossRef]

1989 (1)

1977 (1)

P. K. Tien, Rev. Mod. Phys. 49, 361 (1977).
[CrossRef]

An, Y. H.

Y. H. An and R. J. Friedman, J. Biomed. Mater. Res. 43, 338 (1998).
[CrossRef] [PubMed]

Bandler, R.

P. Feng, in Bacterial Analytical Manual, G. J. Jackson, R. I. Merker, and R. Bandler (U.S. Food and Drug Administration, Washington, D.C., 2001), App. 1; http://vm.cfsan.fda.gov/~ebam/bam-al.html.

Brackett, R. E.

K. H. Seo, R. E. Brackett, N. F. Hartman, and D. P. Campbell, J. Food Protection 62, 431 (1999).

Campbell, D. P.

K. H. Seo, R. E. Brackett, N. F. Hartman, and D. P. Campbell, J. Food Protection 62, 431 (1999).

Deacon, J. K.

A. N. Sloper, J. K. Deacon, and M. T. Falnagan, Sens. Actuators B 1, 589 (1990).
[CrossRef]

Falnagan, M. T.

A. N. Sloper, J. K. Deacon, and M. T. Falnagan, Sens. Actuators B 1, 589 (1990).
[CrossRef]

Feng, P.

P. Feng, in Bacterial Analytical Manual, G. J. Jackson, R. I. Merker, and R. Bandler (U.S. Food and Drug Administration, Washington, D.C., 2001), App. 1; http://vm.cfsan.fda.gov/~ebam/bam-al.html.

Forbes, B. A.

B. A. Forbes, D. F. Sahm, and A. S. Weissfeld, Diagnostic Microbiology (Mosby, St. Louis, Mo., 1998), Chap. 15.

Fratamico, P. M.

P. M. Fratamico, T. P. Strobaugh, M. B. Medina, and A. G. Gehring, Biotechnol. Tech. 12, 571 (1998).
[CrossRef]

Friedman, R. J.

Y. H. An and R. J. Friedman, J. Biomed. Mater. Res. 43, 338 (1998).
[CrossRef] [PubMed]

Gehring, A. G.

P. M. Fratamico, T. P. Strobaugh, M. B. Medina, and A. G. Gehring, Biotechnol. Tech. 12, 571 (1998).
[CrossRef]

Hartman, N. F.

K. H. Seo, R. E. Brackett, N. F. Hartman, and D. P. Campbell, J. Food Protection 62, 431 (1999).

Horváth, R.

R. Horváth, L. R. Lindvold, and N. B. Larsen, Appl. Phys. B 74, 383 (2002).
[CrossRef]

R. Horváth, H. C. Pedersen, and N. B. Larsen, Appl. Phys. Lett. 81, 2166 (2002).
[CrossRef]

Jackson, G. J.

P. Feng, in Bacterial Analytical Manual, G. J. Jackson, R. I. Merker, and R. Bandler (U.S. Food and Drug Administration, Washington, D.C., 2001), App. 1; http://vm.cfsan.fda.gov/~ebam/bam-al.html.

Larsen, N. B.

R. Horváth, L. R. Lindvold, and N. B. Larsen, Appl. Phys. B 74, 383 (2002).
[CrossRef]

R. Horváth, H. C. Pedersen, and N. B. Larsen, Appl. Phys. Lett. 81, 2166 (2002).
[CrossRef]

Lindvold, L. R.

R. Horváth, L. R. Lindvold, and N. B. Larsen, Appl. Phys. B 74, 383 (2002).
[CrossRef]

Lowe, C. R.

H. J. Watts, C. R. Lowe, and D. V. Pollard-Knight, Anal. Chem. 66, 2465 (1994).
[CrossRef] [PubMed]

Lukosz, W.

Medina, M. B.

P. M. Fratamico, T. P. Strobaugh, M. B. Medina, and A. G. Gehring, Biotechnol. Tech. 12, 571 (1998).
[CrossRef]

Merker, R. I.

P. Feng, in Bacterial Analytical Manual, G. J. Jackson, R. I. Merker, and R. Bandler (U.S. Food and Drug Administration, Washington, D.C., 2001), App. 1; http://vm.cfsan.fda.gov/~ebam/bam-al.html.

Pedersen, H. C.

R. Horváth, H. C. Pedersen, and N. B. Larsen, Appl. Phys. Lett. 81, 2166 (2002).
[CrossRef]

Pollard-Knight, D. V.

H. J. Watts, C. R. Lowe, and D. V. Pollard-Knight, Anal. Chem. 66, 2465 (1994).
[CrossRef] [PubMed]

Ren, Y.

Y. Ren, Opt. Mater. 19, 443 (2002).
[CrossRef]

Sahm, D. F.

B. A. Forbes, D. F. Sahm, and A. S. Weissfeld, Diagnostic Microbiology (Mosby, St. Louis, Mo., 1998), Chap. 15.

Seo, K. H.

K. H. Seo, R. E. Brackett, N. F. Hartman, and D. P. Campbell, J. Food Protection 62, 431 (1999).

Sloper, A. N.

A. N. Sloper, J. K. Deacon, and M. T. Falnagan, Sens. Actuators B 1, 589 (1990).
[CrossRef]

Strobaugh, T. P.

P. M. Fratamico, T. P. Strobaugh, M. B. Medina, and A. G. Gehring, Biotechnol. Tech. 12, 571 (1998).
[CrossRef]

Tiefenthaler, K.

Tien, P. K.

P. K. Tien, Rev. Mod. Phys. 49, 361 (1977).
[CrossRef]

Watts, H. J.

H. J. Watts, C. R. Lowe, and D. V. Pollard-Knight, Anal. Chem. 66, 2465 (1994).
[CrossRef] [PubMed]

Weissfeld, A. S.

B. A. Forbes, D. F. Sahm, and A. S. Weissfeld, Diagnostic Microbiology (Mosby, St. Louis, Mo., 1998), Chap. 15.

Anal. Chem. (1)

H. J. Watts, C. R. Lowe, and D. V. Pollard-Knight, Anal. Chem. 66, 2465 (1994).
[CrossRef] [PubMed]

Appl. Phys. B (1)

R. Horváth, L. R. Lindvold, and N. B. Larsen, Appl. Phys. B 74, 383 (2002).
[CrossRef]

Appl. Phys. Lett. (1)

R. Horváth, H. C. Pedersen, and N. B. Larsen, Appl. Phys. Lett. 81, 2166 (2002).
[CrossRef]

Biotechnol. Tech. (1)

P. M. Fratamico, T. P. Strobaugh, M. B. Medina, and A. G. Gehring, Biotechnol. Tech. 12, 571 (1998).
[CrossRef]

J. Biomed. Mater. Res. (1)

Y. H. An and R. J. Friedman, J. Biomed. Mater. Res. 43, 338 (1998).
[CrossRef] [PubMed]

J. Food Protection (1)

K. H. Seo, R. E. Brackett, N. F. Hartman, and D. P. Campbell, J. Food Protection 62, 431 (1999).

J. Opt. Soc. Am. B (1)

Opt. Mater. (1)

Y. Ren, Opt. Mater. 19, 443 (2002).
[CrossRef]

Rev. Mod. Phys. (1)

P. K. Tien, Rev. Mod. Phys. 49, 361 (1977).
[CrossRef]

Sens. Actuators B (1)

A. N. Sloper, J. K. Deacon, and M. T. Falnagan, Sens. Actuators B 1, 589 (1990).
[CrossRef]

Sens. Actuators B (1)

W. Lukosz, Sens. Actuators B 29, 37 (1995).
[CrossRef]

Other (2)

P. Feng, in Bacterial Analytical Manual, G. J. Jackson, R. I. Merker, and R. Bandler (U.S. Food and Drug Administration, Washington, D.C., 2001), App. 1; http://vm.cfsan.fda.gov/~ebam/bam-al.html.

B. A. Forbes, D. F. Sahm, and A. S. Weissfeld, Diagnostic Microbiology (Mosby, St. Louis, Mo., 1998), Chap. 15.

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (4)

Fig. 1
Fig. 1

Reverse symmetry waveguide sensor: PLL, poly-l-lysine.

Fig. 2
Fig. 2

Intensity of incoupled light versus angle of incidence.

Fig. 3
Fig. 3

Peak position versus time. Upper traces, raw data points taken directly from the detector; lower traces, processed data to which drift compensation and 15-point averaging have been applied.

Fig. 4
Fig. 4

Microscope image of the waveguide surface after E. coli attachment.

Metrics