Abstract

We describe the design, construction, and application of what are believed to be the smallest fiber-optic probes used to date during imaging or diagnosis involving low-coherence interferometry (LCI). The probes use novel fiber-optic gradient-index (GRIN) lenses fabricated by a recently developed modified chemical-vapor-deposition (MCVD) process that avoids on-axis aberrations commonly marring MCVD-fabricated GRIN substrate. Fusing GRIN fiber lenses onto single-mode fiber yields automatically aligned all-fiber probes that insert into tissue through hypodermic needles as small as 31-gauge (inner diameter, 127 µm). We demonstrate the use of such probes with LCI by measuring microscopic brain motions in vivo.

© 2002 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Graded-index fiber lens proposed for ultrasmall probes used in biomedical imaging

Youxin Mao, Shoude Chang, Sherif Sherif, and Costel Flueraru
Appl. Opt. 46(23) 5887-5894 (2007)

High-sensitivity anastigmatic imaging needle for optical coherence tomography

Loretta Scolaro, Dirk Lorenser, Robert A. McLaughlin, Bryden C. Quirk, Rodney W. Kirk, and David D. Sampson
Opt. Lett. 37(24) 5247-5249 (2012)

Deep-tissue access with confocal fluorescence microendoscopy through hypodermic needles

Rajesh S. Pillai, Dirk Lorenser, and David D. Sampson
Opt. Express 19(8) 7213-7221 (2011)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (2)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription