Real-time, high velocity-resolution color Doppler optical coherence tomography

Abstract

Color Doppler optical coherence tomography (CDOCT) is a noninvasive optical imaging technique for micro-meter-scale physiological flow mapping simultaneously with morphological optical coherence tomography imaging. We have developed a novel CDOCT signal-processing strategy capable of imaging physiological flow rates at 8 frames/s. Our new strategy features hardware-implemented digital autocorrelation across subsequent scans, permitting us to measure 300-Hz–8-kHz Doppler shifts upon signals of 0.6-MHz bandwidth. The performance of the CDOCT system was demonstrated in a flow phantom and in vivo in Xenopus laevis.

© 2002 Optical Society of America

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