Abstract

We report high-precision measurements of the absorption and the reduced scattering coefficients for turbid media. Using a frequency-domain measurement technique for a point-source infinite-medium geometry, we find that the standard deviations of multiple measurements of the absorption coefficient μ<sub><i>a</i></sub> and the reduced scattering coefficient μ<sub><i>s</i></sub><sup>′</sup> are less than 0.6%, and three independently derived values for μ<sub><i>a</i></sub> and μ<sub><i>s</i></sub><sup>′</sup> agree to better than 1%. Measurements of μ<sub><i>a</i></sub> agree with measurements of a nonscattering medium to within 1.2%. To obtain high precision requires attention to proper conditions for the spherical photon-density wave model, the detection linearity, and the ratio of the absorption rate to the source modulation rate. Frequency-domain amplitude and phase measurements deviate from fitted curves by 0.1% and 0.06 ° rms, respectively.

© 1999 Optical Society of America

PDF Article

References

  • View by:
  • |
  • |
  • |

  1. J. G. Fujimoto and M. S. Patterson, eds., Advances in Optical Imaging and Photon Migration, Vol. 21 of OSA Trends in Optics and Photonics Series (Optical Society of America, Washington, D.C., 1998).
  2. B. Chance, R. R. Alfano, and B. J. Tromberg, eds., Optical Tomography and Spectroscopy of Tissue III, Proc. SPIE 3597, (1999).
  3. B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).
  4. S. Fantini, M. A. Franceschini, J. B. Fishkin, B. Barbieri, and E. Gratton, Appl. Opt. 33, 5204 (1994).
  5. M. Gerken and G. W. Faris, Proc. SPIE 3597, xxx (1999).
  6. M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, Phys. Rev. Lett. 69, 2658 (1992).
  7. R. Aronson and N. Corngold, J. Opt. Soc. Am. A 16, 1066 (1999).
  8. S. Fantini, M. A. Franceschini, and E. Gratton, Appl. Opt. 36, 156 (1997).
  9. K. Rinzema, L. H. P. Murrer, and W. M. Star, J. Opt. Soc. Am. A 15, 2078 (1998).
  10. G. M. Hale and M. R. Querry, Appl. Opt. 12, 555 (1973).

1999

B. Chance, R. R. Alfano, and B. J. Tromberg, eds., Optical Tomography and Spectroscopy of Tissue III, Proc. SPIE 3597, (1999).

R. Aronson and N. Corngold, J. Opt. Soc. Am. A 16, 1066 (1999).

1998

K. Rinzema, L. H. P. Murrer, and W. M. Star, J. Opt. Soc. Am. A 15, 2078 (1998).

B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).

J. G. Fujimoto and M. S. Patterson, eds., Advances in Optical Imaging and Photon Migration, Vol. 21 of OSA Trends in Optics and Photonics Series (Optical Society of America, Washington, D.C., 1998).

1997

S. Fantini, M. A. Franceschini, and E. Gratton, Appl. Opt. 36, 156 (1997).

1994

1992

M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, Phys. Rev. Lett. 69, 2658 (1992).

1973

Aronson, R.

Barbieri, B.

Boas, D. A.

M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, Phys. Rev. Lett. 69, 2658 (1992).

Chance, B.

B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).

M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, Phys. Rev. Lett. 69, 2658 (1992).

Cope, M.

B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).

Corngold, N.

Fantini, S.

S. Fantini, M. A. Franceschini, and E. Gratton, Appl. Opt. 36, 156 (1997).

S. Fantini, M. A. Franceschini, J. B. Fishkin, B. Barbieri, and E. Gratton, Appl. Opt. 33, 5204 (1994).

Faris, G. W.

M. Gerken and G. W. Faris, Proc. SPIE 3597, xxx (1999).

Fishkin, J. B.

Franceschini, M. A.

S. Fantini, M. A. Franceschini, and E. Gratton, Appl. Opt. 36, 156 (1997).

S. Fantini, M. A. Franceschini, J. B. Fishkin, B. Barbieri, and E. Gratton, Appl. Opt. 33, 5204 (1994).

Gerken, M.

M. Gerken and G. W. Faris, Proc. SPIE 3597, xxx (1999).

Gratton, E.

B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).

S. Fantini, M. A. Franceschini, and E. Gratton, Appl. Opt. 36, 156 (1997).

S. Fantini, M. A. Franceschini, J. B. Fishkin, B. Barbieri, and E. Gratton, Appl. Opt. 33, 5204 (1994).

Hale, G. M.

Murrer, L. H. P.

O'Leary, M. A.

M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, Phys. Rev. Lett. 69, 2658 (1992).

Querry, M. R.

Ramanujam, N.

B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).

Rinzema, K.

Star, W. M.

Tromberg, B.

B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).

Yodh, A. G.

M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, Phys. Rev. Lett. 69, 2658 (1992).

Appl. Opt.

S. Fantini, M. A. Franceschini, and E. Gratton, Appl. Opt. 36, 156 (1997).

Appl. Opt.

J. Opt. Soc. Am. A

Phys. Rev. Lett.

M. A. O'Leary, D. A. Boas, B. Chance, and A. G. Yodh, Phys. Rev. Lett. 69, 2658 (1992).

Proc. SPIE

B. Chance, R. R. Alfano, and B. J. Tromberg, eds., Optical Tomography and Spectroscopy of Tissue III, Proc. SPIE 3597, (1999).

M. Gerken and G. W. Faris, Proc. SPIE 3597, xxx (1999).

Rev. Sci. Instrum.

B. Chance, M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg, Rev. Sci. Instrum. 69, 3457 (1998).

Other

J. G. Fujimoto and M. S. Patterson, eds., Advances in Optical Imaging and Photon Migration, Vol. 21 of OSA Trends in Optics and Photonics Series (Optical Society of America, Washington, D.C., 1998).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Metrics