Abstract

Optical and optoacoustic (photoacoustic) microscopy have been recently joined in hybrid implementations that resolve extended tissue contrast compared to each modality alone. Nevertheless, the application of the hybrid technique is limited by the requirement to combine an optical objective with ultrasound detection collecting signal from the same micro-volume. We present an all-optical optoacoustic microscope based on a pi-phase-shifted fiber Bragg grating (π-FBG) with coherence-restored pulsed interferometry (CRPI) used as the interrogation method. The sensor offers an ultra-small footprint and achieved higher sensitivity over piezoelectric transducers of similar size. We characterize the spectral bandwidth of the ultrasound detector and interrogate the imaging performance on phantoms and tissues. We show the first optoacoustic images of biological specimen recorded with π-FBG sensors. We discuss the potential uses of π-FBG sensors based on CRPI.

© 2016 Optical Society of America

Full Article  |  PDF Article
More Like This
Hybrid optical and acoustic resolution optoacoustic endoscopy

Hailong He, Georg Wissmeyer, Saak V. Ovsepian, Andreas Buehler, and Vasilis Ntziachristos
Opt. Lett. 41(12) 2708-2710 (2016)

Single all-fiber-based nanosecond-pulsed supercontinuum source for multispectral photoacoustic microscopy and optical coherence tomography

Xiao Shu, Magalie Bondu, Biqin Dong, Adrian Podoleanu, Lasse Leick, and Hao F. Zhang
Opt. Lett. 41(12) 2743-2746 (2016)

Fiber interferometer for hybrid optical and optoacoustic intravital microscopy

Rami Shnaiderman, Georg Wissmeyer, Markus Seeger, Dominik Soliman, Hector Estrada, Daniel Razansky, Amir Rosenthal, and Vasilis Ntziachristos
Optica 4(10) 1180-1187 (2017)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription