Expand this Topic clickable element to expand a topic
Skip to content
Optica Publishing Group

Imaging magnetically labeled cells with magnetomotive optical coherence tomography

Not Accessible

Your library or personal account may give you access

Abstract

We introduce a novel contrast mechanism for optical coherence tomography (OCT) whereby the optical scattering of magnetically labeled cells is modified by means of an externally applied magnetic field. This modification is made through the addition of a small electromagnet to the imaging arm of a conventional OCT interferometer. We measure the magnetomotive OCT signal by differencing pairs of axial scans (A-scans) acquired with the magnetic field on and off. Magnetomotive contrast is demonstrated in bulk three-dimensional cell scaffolds containing macrophages labeled with microparticles of iron oxide, demonstrating magnetic-specific contrast over a dynamic range of 30dB.

© 2005 Optical Society of America

Full Article  |  PDF Article
More Like This
Magnetomotive contrast for in vivo optical coherence tomography

Amy L. Oldenburg, Farah Jean-Jacques Toublan, Kenneth S. Suslick, Alexander Wei, and Stephen A. Boppart
Opt. Express 13(17) 6597-6614 (2005)

Phase-resolved magnetomotive OCT for imaging nanomolar concentrations of magnetic nanoparticles in tissues

Amy L. Oldenburg, Vasilica Crecea, Stephanie A. Rinne, and Stephen A. Boppart
Opt. Express 16(15) 11525-11539 (2008)

Dual-coil magnetomotive optical coherence tomography for contrast enhancement in liquids

Jongsik Kim, Adeel Ahmad, and Stephen A. Boppart
Opt. Express 21(6) 7139-7147 (2013)

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Figures (3)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Equations (2)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an Optica member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access Optica Member Subscription

Select as filters


Select Topics Cancel
© Copyright 2024 | Optica Publishing Group. All Rights Reserved