Abstract

Improving the axial resolution by providing wider bandwidth wavelength swept lasers remains an important issue for optical frequency domain imaging (OFDI). Here, we demonstrate a wide tuning range, all-fiber wavelength swept laser at a center wavelength of 1250 nm by combining two ring cavities that share a single Fabry-Perot tunable filter. The two cavities contain semiconductor optical amplifiers with central wavelengths of 1190 nm and 1292 nm, respectively. To avoid disturbing interference effects in the overlapping spectral region, we modulated the amplifiers in order to obtain consecutive wavelength sweeps in the two spectral regions. The two sweeps were fused together in post-processing to achieve a total scanning range of 223 nm, corresponding to 3.3 µm axial resolution in air. We confirm improved image quality and reduced speckle size in tomograms of swine esophagus ex vivo, and human skin and nailbed in vivo.

© 2017 Optical Society of America

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    [Crossref] [PubMed]
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  34. A. Bilenca, S. H. Yun, G. J. Tearney, and B. E. Bouma, “Numerical study of wavelength-swept semiconductor ring lasers: the role of refractive-index nonlinearities in semiconductor optical amplifiers and implications for biomedical imaging applications,” Opt. Lett. 31(6), 760–762 (2006).
    [Crossref] [PubMed]
  35. S. Yun, G. Tearney, J. de Boer, N. Iftimia, and B. Bouma, “High-speed optical frequency-domain imaging,” Opt. Express 11(22), 2953–2963 (2003).
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2014 (1)

2013 (1)

H. Kim, J. Lim, J. Ha, and W. Jang, “Broadband wavelength swept source combining a quantum dot and a quantum well SOA in the wavelength range of 1153–1366 nm,” Electron. Lett. 49(19), 1205–1206 (2013).
[Crossref]

2012 (1)

2011 (1)

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

2010 (2)

W. Wieser, B. R. Biedermann, T. Klein, C. M. Eigenwillig, and R. Huber, “Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second,” Opt. Express 18(14), 14685–14704 (2010).
[Crossref] [PubMed]

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

2009 (2)

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Y. Nakazaki and S. Yamashita, “Fast and wide tuning range wavelength-swept fiber laser based on dispersion tuning and its application to dynamic FBG sensing,” Opt. Express 17(10), 8310–8318 (2009).
[Crossref] [PubMed]

2008 (4)

M. Y. Jeon, J. Zhang, Q. Wang, and Z. Chen, “High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs,” Opt. Express 16(4), 2547–2554 (2008).
[Crossref] [PubMed]

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

G. Guagliumi and V. Sirbu, “Optical coherence tomography: high resolution intravascular imaging to evaluate vascular healing after coronary stenting,” Catheter. Cardiovasc. Interv. 72(2), 237–247 (2008).
[Crossref] [PubMed]

W. Drexler and J. G. Fujimoto, “State-of-the-art retinal optical coherence tomography,” Prog. Retin. Eye Res. 27(1), 45–88 (2008).
[Crossref] [PubMed]

2007 (2)

2006 (2)

2005 (3)

2004 (5)

2003 (6)

2000 (1)

1997 (2)

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Adler, D. C.

D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, “Three-dimensional endomicroscopy using optical coherence tomography,” Nat. Photonics 1(12), 709–716 (2007).
[Crossref]

An, X.

Bajraszewski, T.

Biedermann, B. R.

Bilenca, A.

Bouma, B.

Bouma, B. E.

C. Jun, M. Villiger, W.-Y. Oh, and B. E. Bouma, “All-fiber wavelength swept ring laser based on Fabry-Perot filter for optical frequency domain imaging,” Opt. Express 22(21), 25805–25814 (2014).
[Crossref] [PubMed]

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

A. Bilenca, S. H. Yun, G. J. Tearney, and B. E. Bouma, “Numerical study of wavelength-swept semiconductor ring lasers: the role of refractive-index nonlinearities in semiconductor optical amplifiers and implications for biomedical imaging applications,” Opt. Lett. 31(6), 760–762 (2006).
[Crossref] [PubMed]

W.-Y. Oh, S.-H. Yun, G. J. Tearney, and B. E. Bouma, “Wide Tuning Range Wavelength-Swept Laser With Two Semiconductor Optical Amplifiers,” IEEE Photonics Technol. Lett. 17(3), 678–680 (2005).
[Crossref] [PubMed]

W. Y. Oh, S. H. Yun, G. J. Tearney, and B. E. Bouma, “115 kHz tuning repetition rate ultrahigh-speed wavelength-swept semiconductor laser,” Opt. Lett. 30(23), 3159–3161 (2005).
[Crossref] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, “Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography,” Opt. Lett. 28(21), 2067–2069 (2003).
[Crossref] [PubMed]

Brenner, M.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Burrow, M. F.

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

Cable, A. E.

Cariou, J.

Caswell, A. W.

Cense, B.

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Chen, Y.

D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, “Three-dimensional endomicroscopy using optical coherence tomography,” Nat. Photonics 1(12), 709–716 (2007).
[Crossref]

Chen, Z.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

M. Y. Jeon, J. Zhang, Q. Wang, and Z. Chen, “High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs,” Opt. Express 16(4), 2547–2554 (2008).
[Crossref] [PubMed]

Y. Wang, Y. Zhao, J. S. Nelson, Z. Chen, and R. S. Windeler, “Ultrahigh-resolution optical coherence tomography by broadband continuum generation from a photonic crystal fiber,” Opt. Lett. 28(3), 182–184 (2003).
[Crossref] [PubMed]

Chinn, S. R.

Choma, M.

Colt, H.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Connolly, J.

D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, “Three-dimensional endomicroscopy using optical coherence tomography,” Nat. Photonics 1(12), 709–716 (2007).
[Crossref]

de Boer, J.

de Boer, J. F.

Drexler, W.

Duker, J.

Duker, J. S.

Eigenwillig, C. M.

et,

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Fercher, A.

Fercher, A. F.

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Fujimoto, J.

Fujimoto, J. G.

I. Grulkowski, J. J. Liu, B. Potsaid, V. Jayaraman, C. D. Lu, J. Jiang, A. E. Cable, J. S. Duker, and J. G. Fujimoto, “Retinal, anterior segment and full eye imaging using ultrahigh speed swept source OCT with vertical-cavity surface emitting lasers,” Biomed. Opt. Express 3(11), 2733–2751 (2012).
[Crossref] [PubMed]

W. Drexler and J. G. Fujimoto, “State-of-the-art retinal optical coherence tomography,” Prog. Retin. Eye Res. 27(1), 45–88 (2008).
[Crossref] [PubMed]

L. A. Kranendonk, X. An, A. W. Caswell, R. E. Herold, S. T. Sanders, R. Huber, J. G. Fujimoto, Y. Okura, and Y. Urata, “High speed engine gas thermometry by Fourier-domain mode-locked laser absorption spectroscopy,” Opt. Express 15(23), 15115–15128 (2007).
[Crossref] [PubMed]

D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, “Three-dimensional endomicroscopy using optical coherence tomography,” Nat. Photonics 1(12), 709–716 (2007).
[Crossref]

R. Huber, M. Wojtkowski, and J. G. Fujimoto, “Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography,” Opt. Express 14(8), 3225–3237 (2006).
[Crossref] [PubMed]

U. Morgner, W. Drexler, F. X. Kärtner, X. D. Li, C. Pitris, E. P. Ippen, and J. G. Fujimoto, “Spectroscopic optical coherence tomography,” Opt. Lett. 25(2), 111–113 (2000).
[Crossref] [PubMed]

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, “Optical coherence tomography using a frequency-tunable optical source,” Opt. Lett. 22(5), 340–342 (1997).
[Crossref] [PubMed]

Gardecki, J. A.

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Grulkowski, I.

Guagliumi, G.

G. Guagliumi and V. Sirbu, “Optical coherence tomography: high resolution intravascular imaging to evaluate vascular healing after coronary stenting,” Catheter. Cardiovasc. Interv. 72(2), 237–247 (2008).
[Crossref] [PubMed]

Guern, Y.

Ha, J.

H. Kim, J. Lim, J. Ha, and W. Jang, “Broadband wavelength swept source combining a quantum dot and a quantum well SOA in the wavelength range of 1153–1366 nm,” Electron. Lett. 49(19), 1205–1206 (2013).
[Crossref]

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Hermann, B.

Herold, R. E.

Hitzenberger, C.

Hitzenberger, C. K.

Hsu, K.

Huang, D.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Huber, R.

Iftimia, N.

Ippen, E. P.

Izatt, J.

Jang, W.

H. Kim, J. Lim, J. Ha, and W. Jang, “Broadband wavelength swept source combining a quantum dot and a quantum well SOA in the wavelength range of 1153–1366 nm,” Electron. Lett. 49(19), 1205–1206 (2013).
[Crossref]

Jayaraman, V.

Jeon, M. Y.

Jiang, J.

Jun, C.

Kärtner, F. X.

Kim, H.

H. Kim, J. Lim, J. Ha, and W. Jang, “Broadband wavelength swept source combining a quantum dot and a quantum well SOA in the wavelength range of 1153–1366 nm,” Electron. Lett. 49(19), 1205–1206 (2013).
[Crossref]

Klein, T.

Ko, T.

Kowalczyk, A.

Kranendonk, L. A.

Kreuter, K.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Kulhavy, M.

Lauwers, G. Y.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Le, T.

Le Brun, G.

Le Jeune, B.

Leitgeb, R.

Lexer, F.

Li, X. D.

Lim, J.

H. Kim, J. Lim, J. Ha, and W. Jang, “Broadband wavelength swept source combining a quantum dot and a quantum well SOA in the wavelength range of 1153–1366 nm,” Electron. Lett. 49(19), 1205–1206 (2013).
[Crossref]

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Liu, G.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Liu, J. J.

Liu, L.

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

Lortrian, J.

Lu, C. D.

Mahon, S.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Mino-Kenudson, M.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Morgner, U.

Mukai, D.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Nadkarni, S. K.

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

Nakazaki, Y.

Nelson, J. S.

Nishioka, N. S.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Oh, W. Y.

Oh, W.-Y.

C. Jun, M. Villiger, W.-Y. Oh, and B. E. Bouma, “All-fiber wavelength swept ring laser based on Fabry-Perot filter for optical frequency domain imaging,” Opt. Express 22(21), 25805–25814 (2014).
[Crossref] [PubMed]

W.-Y. Oh, S.-H. Yun, G. J. Tearney, and B. E. Bouma, “Wide Tuning Range Wavelength-Swept Laser With Two Semiconductor Optical Amplifiers,” IEEE Photonics Technol. Lett. 17(3), 678–680 (2005).
[Crossref] [PubMed]

Okura, Y.

Ozawa, N.

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

Park, B. H.

Peavy, G. M.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Piederrière, Y.

Pierce, M. C.

Pitris, C.

Potsaid, B.

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Sadr, A.

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

Sanders, S. T.

Sarunic, M.

Schmitt, J.

D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, “Three-dimensional endomicroscopy using optical coherence tomography,” Nat. Photonics 1(12), 709–716 (2007).
[Crossref]

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Shimada, Y.

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

Shishkov, M.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Sirbu, V.

G. Guagliumi and V. Sirbu, “Optical coherence tomography: high resolution intravascular imaging to evaluate vascular healing after coronary stenting,” Catheter. Cardiovasc. Interv. 72(2), 237–247 (2008).
[Crossref] [PubMed]

Srinivasan, V.

Stingl, A.

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Sumi, Y.

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

Suter, M. J.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Swanson, E. A.

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, “Optical coherence tomography using a frequency-tunable optical source,” Opt. Lett. 22(5), 340–342 (1997).
[Crossref] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Tagami, J.

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

Taira, K.

Tearney, G.

Tearney, G. J.

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

A. Bilenca, S. H. Yun, G. J. Tearney, and B. E. Bouma, “Numerical study of wavelength-swept semiconductor ring lasers: the role of refractive-index nonlinearities in semiconductor optical amplifiers and implications for biomedical imaging applications,” Opt. Lett. 31(6), 760–762 (2006).
[Crossref] [PubMed]

W.-Y. Oh, S.-H. Yun, G. J. Tearney, and B. E. Bouma, “Wide Tuning Range Wavelength-Swept Laser With Two Semiconductor Optical Amplifiers,” IEEE Photonics Technol. Lett. 17(3), 678–680 (2005).
[Crossref] [PubMed]

W. Y. Oh, S. H. Yun, G. J. Tearney, and B. E. Bouma, “115 kHz tuning repetition rate ultrahigh-speed wavelength-swept semiconductor laser,” Opt. Lett. 30(23), 3159–3161 (2005).
[Crossref] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, “Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography,” Opt. Lett. 28(21), 2067–2069 (2003).
[Crossref] [PubMed]

Toussaint, J. D.

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

Unterhuber, A.

Urata, Y.

Vakoc, B. J.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Villiger, M.

Wang, Q.

Wang, Y.

Wieser, W.

Windeler, R. S.

Wojtkowski, M.

Xie, T.

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

Yachimski, P. S.

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

Yagi, Y.

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

Yamashita, S.

Yang, C.

Yun, S.

Yun, S. H.

Yun, S.-H.

W.-Y. Oh, S.-H. Yun, G. J. Tearney, and B. E. Bouma, “Wide Tuning Range Wavelength-Swept Laser With Two Semiconductor Optical Amplifiers,” IEEE Photonics Technol. Lett. 17(3), 678–680 (2005).
[Crossref] [PubMed]

Zhang, J.

Zhao, Y.

Appl. Opt. (1)

Biomed. Opt. Express (1)

Catheter. Cardiovasc. Interv. (1)

G. Guagliumi and V. Sirbu, “Optical coherence tomography: high resolution intravascular imaging to evaluate vascular healing after coronary stenting,” Catheter. Cardiovasc. Interv. 72(2), 237–247 (2008).
[Crossref] [PubMed]

Electron. Lett. (1)

H. Kim, J. Lim, J. Ha, and W. Jang, “Broadband wavelength swept source combining a quantum dot and a quantum well SOA in the wavelength range of 1153–1366 nm,” Electron. Lett. 49(19), 1205–1206 (2013).
[Crossref]

Gastrointest. Endosc. (1)

M. J. Suter, B. J. Vakoc, P. S. Yachimski, M. Shishkov, G. Y. Lauwers, M. Mino-Kenudson, B. E. Bouma, N. S. Nishioka, and G. J. Tearney, “Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging,” Gastrointest. Endosc. 68(4), 745–753 (2008).
[Crossref] [PubMed]

IEEE Photonics Technol. Lett. (1)

W.-Y. Oh, S.-H. Yun, G. J. Tearney, and B. E. Bouma, “Wide Tuning Range Wavelength-Swept Laser With Two Semiconductor Optical Amplifiers,” IEEE Photonics Technol. Lett. 17(3), 678–680 (2005).
[Crossref] [PubMed]

J. Biomed. Opt. (1)

T. Xie, G. Liu, K. Kreuter, S. Mahon, H. Colt, D. Mukai, G. M. Peavy, Z. Chen, and M. Brenner, “In vivo three-dimensional imaging of normal tissue and tumors in the rabbit pleural cavity using endoscopic swept source optical coherence tomography with thoracoscopic guidance,” J. Biomed. Opt. 14(6), 064045 (2009).
[Crossref] [PubMed]

J. Dent. (1)

Y. Shimada, A. Sadr, M. F. Burrow, J. Tagami, N. Ozawa, and Y. Sumi, “Validation of swept-source optical coherence tomography (SS-OCT) for the diagnosis of occlusal caries,” J. Dent. 38(8), 655–665 (2010).
[Crossref] [PubMed]

Nat. Med. (1)

L. Liu, J. A. Gardecki, S. K. Nadkarni, J. D. Toussaint, Y. Yagi, B. E. Bouma, and G. J. Tearney, “Imaging the subcellular structure of human coronary atherosclerosis using micro-optical coherence tomography,” Nat. Med. 17(8), 1010–1014 (2011).
[Crossref] [PubMed]

Nat. Photonics (1)

D. C. Adler, Y. Chen, R. Huber, J. Schmitt, J. Connolly, and J. G. Fujimoto, “Three-dimensional endomicroscopy using optical coherence tomography,” Nat. Photonics 1(12), 709–716 (2007).
[Crossref]

Opt. Express (16)

R. Leitgeb, C. Hitzenberger, and A. Fercher, “Performance of fourier domain vs. time domain optical coherence tomography,” Opt. Express 11(8), 889–894 (2003).
[Crossref] [PubMed]

C. Jun, M. Villiger, W.-Y. Oh, and B. E. Bouma, “All-fiber wavelength swept ring laser based on Fabry-Perot filter for optical frequency domain imaging,” Opt. Express 22(21), 25805–25814 (2014).
[Crossref] [PubMed]

R. Huber, M. Wojtkowski, and J. G. Fujimoto, “Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography,” Opt. Express 14(8), 3225–3237 (2006).
[Crossref] [PubMed]

L. A. Kranendonk, X. An, A. W. Caswell, R. E. Herold, S. T. Sanders, R. Huber, J. G. Fujimoto, Y. Okura, and Y. Urata, “High speed engine gas thermometry by Fourier-domain mode-locked laser absorption spectroscopy,” Opt. Express 15(23), 15115–15128 (2007).
[Crossref] [PubMed]

M. Y. Jeon, J. Zhang, Q. Wang, and Z. Chen, “High-speed and wide bandwidth Fourier domain mode-locked wavelength swept laser with multiple SOAs,” Opt. Express 16(4), 2547–2554 (2008).
[Crossref] [PubMed]

Y. Nakazaki and S. Yamashita, “Fast and wide tuning range wavelength-swept fiber laser based on dispersion tuning and its application to dynamic FBG sensing,” Opt. Express 17(10), 8310–8318 (2009).
[Crossref] [PubMed]

W. Wieser, B. R. Biedermann, T. Klein, C. M. Eigenwillig, and R. Huber, “Multi-megahertz OCT: High quality 3D imaging at 20 million A-scans and 4.5 GVoxels per second,” Opt. Express 18(14), 14685–14704 (2010).
[Crossref] [PubMed]

S. Yun, G. Tearney, J. de Boer, N. Iftimia, and B. Bouma, “High-speed optical frequency-domain imaging,” Opt. Express 11(22), 2953–2963 (2003).
[Crossref] [PubMed]

S. Yun, G. Tearney, J. de Boer, N. Iftimia, and B. Bouma, “High-speed optical frequency-domain imaging,” Opt. Express 11(22), 2953–2963 (2003).
[Crossref] [PubMed]

Y. Piederrière, J. Cariou, Y. Guern, B. Le Jeune, G. Le Brun, and J. Lortrian, “Scattering through fluids: speckle size measurement and Monte Carlo simulations close to and into the multiple scattering,” Opt. Express 12(1), 176–188 (2004).
[Crossref] [PubMed]

M. Choma, M. Sarunic, C. Yang, and J. Izatt, “Sensitivity advantage of swept source and Fourier domain optical coherence tomography,” Opt. Express 11(18), 2183–2189 (2003).
[Crossref] [PubMed]

R. Leitgeb, W. Drexler, A. Unterhuber, B. Hermann, T. Bajraszewski, T. Le, A. Stingl, and A. Fercher, “Ultrahigh resolution Fourier domain optical coherence tomography,” Opt. Express 12(10), 2156–2165 (2004).
[Crossref] [PubMed]

M. Wojtkowski, V. Srinivasan, T. Ko, J. Fujimoto, A. Kowalczyk, and J. Duker, “Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation,” Opt. Express 12(11), 2404–2422 (2004).
[Crossref] [PubMed]

S. H. Yun, G. Tearney, J. de Boer, and B. Bouma, “Motion artifacts in optical coherence tomography with frequency-domain ranging,” Opt. Express 12(13), 2977–2998 (2004).
[Crossref] [PubMed]

S. Yun, G. Tearney, J. de Boer, and B. Bouma, “Removing the depth-degeneracy in optical frequency domain imaging with frequency shifting,” Opt. Express 12(20), 4822–4828 (2004).
[Crossref] [PubMed]

R. Huber, M. Wojtkowski, K. Taira, J. Fujimoto, and K. Hsu, “Amplified, frequency swept lasers for frequency domain reflectometry and OCT imaging: design and scaling principles,” Opt. Express 13(9), 3513–3528 (2005).
[Crossref] [PubMed]

Opt. Lett. (6)

Prog. Retin. Eye Res. (1)

W. Drexler and J. G. Fujimoto, “State-of-the-art retinal optical coherence tomography,” Prog. Retin. Eye Res. 27(1), 45–88 (2008).
[Crossref] [PubMed]

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and et, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[Crossref] [PubMed]

Other (2)

B. Potsaid, V. Jayaraman, J. G. Fujimoto, J. Jiang, P. J. S. Heim, and A. E. Cable, “MEMS tunable VCSEL light source for ultrahigh speed 60kHz - 1MHz axial scan rate and long range centimeter class OCT imaging,” in J. A. Izatt, J. G. Fujimoto, and V. V. Tuchin, eds. (International Society for Optics and Photonics, 2012), p. 82130M.

M. Kuznetsov, W. Atia, B. Johnson, and D. Flanders, “Compact ultrafast reflective Fabry-Perot tunable lasers for OCT imaging applications,” in J. A. Izatt, J. G. Fujimoto, and V. V. Tuchin, eds. (International Society for Optics and Photonics, 2010), p. 75541F.

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Figures (7)

Fig. 1
Fig. 1 (a) Experimental setup of the extended bandwidth wavelength swept laser. (b) Amplified spontaneous emission (ASE) spectra of the two semiconductor optical amplifiers (SOAs). (c) Timing of filter driving and laser modulation signals. PC: polarization controller, WDM: Wavelength division multiplexer.

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Fig. 2
Fig. 2 (a) Optical spectra of the extended bandwidth wavelength swept laser, and each individual single band laser. (b) Estimated axial resolution by inverse Fourier transforming the source spectra.

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Fig. 3
Fig. 3 (a) Schematic of the OCT system for evaluation of the extended bandwidth swept source. (b) Laser time trace and interference fringe signal. SMF: single mode fiber, AO FS: acousto-optic frequency shifter, PC: Polarization controller, FBG: fiber Bragg grating, PD: photo detector

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Fig. 4
Fig. 4 Mapped and dispersion compensated depth-scans for band-1 (a), and band-2 (b), respectively. Same depth-scans, after additional calibration and zero-padding to N1 + N2 points resulting in equal depth positions for band-1 (c) and band-2 (d). (e) Standard deviation of the phase difference between band-1 and band-2 across all peak positions as a function of the relative offset in wavenumber indices between the two bands. (f) Synthesized fringe signals of an individual peak after applying correct wavenumber offset and an additional scalar phase value.

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Fig. 5
Fig. 5 (a) Axial point spread functions (PSFs) for various axial peak positions for the two individual and the combined spectra, (b) Zoomed-in version of one of the peaks (c) full-width at half-maximum (FWHM) of the axial PSFs for the individual and the combined spectra

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Fig. 6
Fig. 6 (a),(b) and (c) OCT tomograms of swine esophagus ex vivo using Band-1, Band-2 and extended bandwidth laser. (d) Zoomed-in versions of dashed regions of interest in each of panels (a)-(c). (e) Lateral mean of the axial autocorrelation of the selected regions of interest.

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Fig. 7
Fig. 7 (a), (b) OCT tomograms of human skin (back of a hand) in vivo for a single band (a) and extended bandwidth laser (b), respectively. (c), (d) OCT images of swine esophagus ex vivo for a single band (c) and extended bandwidth laser (d). (e), (f) Images of a human finger (nailbed) in vivo for a single band (e) and extended bandwidth laser (f). Insets: 2x magnified view of the dashed regions.

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Tables (1)

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Table 1 Calibration and fusion process

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Equations (1)

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δz= 2ln2 π λ ∘ 2 nΔλ ,

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