Abstract

Digital in-line holographic microscopy (DIHM) has attracted attention because of its simple but powerful three-dimensional (3D) imaging capability. To improve the spatial resolution, 3D image reconstruction algorithms use numerical magnification, which generates distortions in the generated images. We propose a method to overcome this problem by using the simple relation between the object and image positions in 3D space. Several holograms were taken while translating a resolution target at different axial positions by a motorized stage. We demonstrated the effectiveness of our method by reconstructing the 3D positions of 3-μm-diameter polymer beads on a tilted slide glass from a single measured hologram.

© 2017 Optical Society of America

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References

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2017 (1)

M. Roy, D. Seo, S. Oh, J.-W. Yang, and S. Seo, “A review of recent progress in lens-free imaging and sensing,” Biosens. Bioelectron. 88, 130–143 (2017).
[Crossref] [PubMed]

2016 (1)

B. K. Chen, T.-Y. Chen, S. G. Hung, S.-L. Huang, and J.-Y. Lin, “Twin image removal in digital in-line holography based on iterative inter-projections,” J. Opt. 18(6), 065602 (2016).
[Crossref]

2014 (2)

M. Roy, G. Jin, D. Seo, M.-H. Nam, and S. Seo, “A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique,” Sens. Actuators B Chem. 201, 321–328 (2014).
[Crossref]

X. Yu, J. Hong, C. Liu, and M. K. Kim, “Review of digital holographic microscopy for three-dimensional profiling and tracking,” Opt. Eng. 53(11), 112306 (2014).
[Crossref]

2013 (2)

Y.-S. Bae, J.-I. Song, and D. Y. Kim, “Volumetric reconstruction of Brownian motion of a micrometer-size bead in water,” Opt. Commun. 309, 291–297 (2013).
[Crossref]

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

2012 (4)

A. P. Mosk, A. Lagendijk, G. Lerosey, and M. Fink, “Controlling waves in space and time for imaging and focusing in complex media,” Nat. Photonics 6(5), 283–292 (2012).
[Crossref]

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

A. Greenbaum, U. Sikora, and A. Ozcan, “Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging,” Lab Chip 12(7), 1242–1245 (2012).
[Crossref] [PubMed]

A. Greenbaum and A. Ozcan, “Maskless imaging of dense samples using pixel super-resolution based multi-height lensfree on-chip microscopy,” Opt. Express 20(3), 3129–3143 (2012).
[Crossref] [PubMed]

2011 (3)

G. Zheng, S. A. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, “The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proc. Natl. Acad. Sci. U.S.A. 108(41), 16889–16894 (2011).
[Crossref] [PubMed]

S. O. Isikman, W. Bishara, H. Zhu, and A. Ozcan, “Optofluidic tomography on a chip,” Appl. Phys. Lett. 98(16), 161109 (2011).
[Crossref] [PubMed]

N. Verrier and M. Atlan, “Off-axis digital hologram reconstruction: some practical considerations,” Appl. Opt. 50(34), H136–H146 (2011).
[Crossref] [PubMed]

2010 (5)

T.-W. Su, S. O. Isikman, W. Bishara, D. Tseng, A. Erlinger, and A. Ozcan, “Multi-angle lensless digital holography for depth resolved imaging on a chip,” Opt. Express 18(9), 9690–9711 (2010).
[Crossref] [PubMed]

W. Bishara, T.-W. Su, A. F. Coskun, and A. Ozcan, “Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution,” Opt. Express 18(11), 11181–11191 (2010).
[Crossref] [PubMed]

W. Qu, O. C. Chee, Y. Yu, and A. Asundi, “Recording and reconstruction of digital Gabor hologram,” Optik-Int. J. Light Electron Opt. 121(23), 2179–2184 (2010).
[Crossref]

V. Micó and Z. Zalevsky, “Superresolved digital in-line holographic microscopy for high-resolution lensless biological imaging,” J. Biomed. Opt. 15(4), 046027 (2010).
[Crossref] [PubMed]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

2009 (2)

S. Seo, T.-W. Su, D. K. Tseng, A. Erlinger, and A. Ozcan, “Lensfree holographic imaging for on-chip cytometry and diagnostics,” Lab Chip 9(6), 777–787 (2009).
[Crossref] [PubMed]

S. Lee, J. Y. Lee, W. Yang, and D. Y. Kim, “Autofocusing and edge detection schemes in cell volume measurements with quantitative phase microscopy,” Opt. Express 17(8), 6476–6486 (2009).
[Crossref] [PubMed]

2008 (1)

2007 (1)

T. Latychevskaia and H.-W. Fink, “Solution to the twin image problem in holography,” Phys. Rev. Lett. 98(23), 233901 (2007).
[Crossref] [PubMed]

2006 (4)

2004 (4)

L. Repetto, E. Piano, and C. Pontiggia, “Lensless digital holographic microscope with light-emitting diode illumination,” Opt. Lett. 29(10), 1132–1134 (2004).
[Crossref] [PubMed]

F. Zhang, I. Yamaguchi, and L. P. Yaroslavsky, “Algorithm for reconstruction of digital holograms with adjustable magnification,” Opt. Lett. 29(14), 1668–1670 (2004).
[Crossref] [PubMed]

Y. Sun, S. Duthaler, and B. J. Nelson, “Autofocusing in computer microscopy: selecting the optimal focus algorithm,” Microsc. Res. Tech. 65(3), 139–149 (2004).
[Crossref] [PubMed]

L. Ma, H. Wang, Y. Li, and H. Jin, “Numerical reconstruction of digital holograms for three-dimensional shape measurement,” J. Opt. A 6(4), 396–400 (2004).
[Crossref]

2002 (2)

U. Schnars and W. P. Jüptner, “Digital recording and numerical reconstruction of holograms,” Meas. Sci. Technol. 13(9), R85–R101 (2002).
[Crossref]

I. Yamaguchi, T. Matsumura, and J. Kato, “Phase-shifting color digital holography,” Opt. Lett. 27(13), 1108–1110 (2002).
[Crossref] [PubMed]

1999 (2)

1994 (1)

1981 (1)

1979 (1)

J. E. Harvey, “Fourier treatment of near‐field scalar diffraction theory,” Am. J. Phys. 47(11), 974–980 (1979).
[Crossref]

1968 (1)

1962 (1)

1948 (1)

D. Gabor, “A new microscopic principle,” Nature 161(4098), 777–778 (1948).
[Crossref] [PubMed]

Antebi, Y.

G. Zheng, S. A. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, “The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proc. Natl. Acad. Sci. U.S.A. 108(41), 16889–16894 (2011).
[Crossref] [PubMed]

Aspert, N.

Asundi, A.

W. Qu, O. C. Chee, Y. Yu, and A. Asundi, “Recording and reconstruction of digital Gabor hologram,” Optik-Int. J. Light Electron Opt. 121(23), 2179–2184 (2010).
[Crossref]

Atlan, M.

Bae, Y.-S.

Y.-S. Bae, J.-I. Song, and D. Y. Kim, “Volumetric reconstruction of Brownian motion of a micrometer-size bead in water,” Opt. Commun. 309, 291–297 (2013).
[Crossref]

Bevilacqua, F.

Bishara, W.

S. O. Isikman, W. Bishara, H. Zhu, and A. Ozcan, “Optofluidic tomography on a chip,” Appl. Phys. Lett. 98(16), 161109 (2011).
[Crossref] [PubMed]

W. Bishara, T.-W. Su, A. F. Coskun, and A. Ozcan, “Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution,” Opt. Express 18(11), 11181–11191 (2010).
[Crossref] [PubMed]

T.-W. Su, S. O. Isikman, W. Bishara, D. Tseng, A. Erlinger, and A. Ozcan, “Multi-angle lensless digital holography for depth resolved imaging on a chip,” Opt. Express 18(9), 9690–9711 (2010).
[Crossref] [PubMed]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Bourquin, S.

Callens, N.

Charrière, F.

Chee, O. C.

W. Qu, O. C. Chee, Y. Yu, and A. Asundi, “Recording and reconstruction of digital Gabor hologram,” Optik-Int. J. Light Electron Opt. 121(23), 2179–2184 (2010).
[Crossref]

Chen, B. K.

B. K. Chen, T.-Y. Chen, S. G. Hung, S.-L. Huang, and J.-Y. Lin, “Twin image removal in digital in-line holography based on iterative inter-projections,” J. Opt. 18(6), 065602 (2016).
[Crossref]

Chen, T.-Y.

B. K. Chen, T.-Y. Chen, S. G. Hung, S.-L. Huang, and J.-Y. Lin, “Twin image removal in digital in-line holography based on iterative inter-projections,” J. Opt. 18(6), 065602 (2016).
[Crossref]

Colomb, T.

Coskun, A. F.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

W. Bishara, T.-W. Su, A. F. Coskun, and A. Ozcan, “Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution,” Opt. Express 18(11), 11181–11191 (2010).
[Crossref] [PubMed]

Cuche, E.

Depeursinge, C.

Dirksen, D.

Dubois, F.

Duthaler, S.

Y. Sun, S. Duthaler, and B. J. Nelson, “Autofocusing in computer microscopy: selecting the optimal focus algorithm,” Microsc. Res. Tech. 65(3), 139–149 (2004).
[Crossref] [PubMed]

Elowitz, M. B.

G. Zheng, S. A. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, “The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proc. Natl. Acad. Sci. U.S.A. 108(41), 16889–16894 (2011).
[Crossref] [PubMed]

Erlinger, A.

T.-W. Su, S. O. Isikman, W. Bishara, D. Tseng, A. Erlinger, and A. Ozcan, “Multi-angle lensless digital holography for depth resolved imaging on a chip,” Opt. Express 18(9), 9690–9711 (2010).
[Crossref] [PubMed]

S. Seo, T.-W. Su, D. K. Tseng, A. Erlinger, and A. Ozcan, “Lensfree holographic imaging for on-chip cytometry and diagnostics,” Lab Chip 9(6), 777–787 (2009).
[Crossref] [PubMed]

Fink, H.-W.

T. Latychevskaia and H.-W. Fink, “Solution to the twin image problem in holography,” Phys. Rev. Lett. 98(23), 233901 (2007).
[Crossref] [PubMed]

Fink, M.

A. P. Mosk, A. Lagendijk, G. Lerosey, and M. Fink, “Controlling waves in space and time for imaging and focusing in complex media,” Nat. Photonics 6(5), 283–292 (2012).
[Crossref]

Gabor, D.

D. Gabor, “A new microscopic principle,” Nature 161(4098), 777–778 (1948).
[Crossref] [PubMed]

Garcia-Sucerquia, J.

Göröcs, Z.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

Greenbaum, A.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

A. Greenbaum and A. Ozcan, “Maskless imaging of dense samples using pixel super-resolution based multi-height lensfree on-chip microscopy,” Opt. Express 20(3), 3129–3143 (2012).
[Crossref] [PubMed]

A. Greenbaum, U. Sikora, and A. Ozcan, “Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging,” Lab Chip 12(7), 1242–1245 (2012).
[Crossref] [PubMed]

Harvey, J. E.

J. E. Harvey, “Fourier treatment of near‐field scalar diffraction theory,” Am. J. Phys. 47(11), 974–980 (1979).
[Crossref]

Hong, J.

X. Yu, J. Hong, C. Liu, and M. K. Kim, “Review of digital holographic microscopy for three-dimensional profiling and tracking,” Opt. Eng. 53(11), 112306 (2014).
[Crossref]

Huang, S.-L.

B. K. Chen, T.-Y. Chen, S. G. Hung, S.-L. Huang, and J.-Y. Lin, “Twin image removal in digital in-line holography based on iterative inter-projections,” J. Opt. 18(6), 065602 (2016).
[Crossref]

Hung, S. G.

B. K. Chen, T.-Y. Chen, S. G. Hung, S.-L. Huang, and J.-Y. Lin, “Twin image removal in digital in-line holography based on iterative inter-projections,” J. Opt. 18(6), 065602 (2016).
[Crossref]

Isikman, S. O.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

S. O. Isikman, W. Bishara, H. Zhu, and A. Ozcan, “Optofluidic tomography on a chip,” Appl. Phys. Lett. 98(16), 161109 (2011).
[Crossref] [PubMed]

T.-W. Su, S. O. Isikman, W. Bishara, D. Tseng, A. Erlinger, and A. Ozcan, “Multi-angle lensless digital holography for depth resolved imaging on a chip,” Opt. Express 18(9), 9690–9711 (2010).
[Crossref] [PubMed]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Jericho, M. H.

Jericho, S. K.

Jin, G.

M. Roy, G. Jin, D. Seo, M.-H. Nam, and S. Seo, “A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique,” Sens. Actuators B Chem. 201, 321–328 (2014).
[Crossref]

Jin, H.

L. Ma, H. Wang, Y. Li, and H. Jin, “Numerical reconstruction of digital holograms for three-dimensional shape measurement,” J. Opt. A 6(4), 396–400 (2004).
[Crossref]

Jüptner, W.

Jüptner, W. P.

U. Schnars and W. P. Jüptner, “Digital recording and numerical reconstruction of holograms,” Meas. Sci. Technol. 13(9), R85–R101 (2002).
[Crossref]

Kato, J.

Katz, J.

Kemper, B.

Khademhosseini, B.

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Kim, D. Y.

Y.-S. Bae, J.-I. Song, and D. Y. Kim, “Volumetric reconstruction of Brownian motion of a micrometer-size bead in water,” Opt. Commun. 309, 291–297 (2013).
[Crossref]

S. Lee, J. Y. Lee, W. Yang, and D. Y. Kim, “Autofocusing and edge detection schemes in cell volume measurements with quantitative phase microscopy,” Opt. Express 17(8), 6476–6486 (2009).
[Crossref] [PubMed]

Kim, M. K.

X. Yu, J. Hong, C. Liu, and M. K. Kim, “Review of digital holographic microscopy for three-dimensional profiling and tracking,” Opt. Eng. 53(11), 112306 (2014).
[Crossref]

Klages, P.

Kreuzer, H. J.

Kühn, J.

Lagendijk, A.

A. P. Mosk, A. Lagendijk, G. Lerosey, and M. Fink, “Controlling waves in space and time for imaging and focusing in complex media,” Nat. Photonics 6(5), 283–292 (2012).
[Crossref]

Lalor, É.

Langehanenberg, P.

Latychevskaia, T.

T. Latychevskaia and H.-W. Fink, “Solution to the twin image problem in holography,” Phys. Rev. Lett. 98(23), 233901 (2007).
[Crossref] [PubMed]

Lee, J. Y.

Lee, S.

Lee, S. A.

G. Zheng, S. A. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, “The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proc. Natl. Acad. Sci. U.S.A. 108(41), 16889–16894 (2011).
[Crossref] [PubMed]

Leith, E. N.

Lerosey, G.

A. P. Mosk, A. Lagendijk, G. Lerosey, and M. Fink, “Controlling waves in space and time for imaging and focusing in complex media,” Nat. Photonics 6(5), 283–292 (2012).
[Crossref]

Li, Y.

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

L. Ma, H. Wang, Y. Li, and H. Jin, “Numerical reconstruction of digital holograms for three-dimensional shape measurement,” J. Opt. A 6(4), 396–400 (2004).
[Crossref]

Lin, J.-Y.

B. K. Chen, T.-Y. Chen, S. G. Hung, S.-L. Huang, and J.-Y. Lin, “Twin image removal in digital in-line holography based on iterative inter-projections,” J. Opt. 18(6), 065602 (2016).
[Crossref]

Liu, C.

X. Yu, J. Hong, C. Liu, and M. K. Kim, “Review of digital holographic microscopy for three-dimensional profiling and tracking,” Opt. Eng. 53(11), 112306 (2014).
[Crossref]

Liu, S.

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

Luo, W.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

Ma, L.

L. Ma, H. Wang, Y. Li, and H. Jin, “Numerical reconstruction of digital holograms for three-dimensional shape measurement,” J. Opt. A 6(4), 396–400 (2004).
[Crossref]

Malkiel, E.

Marian, A.

Marquet, P.

Matsumura, T.

Micó, V.

V. Micó and Z. Zalevsky, “Superresolved digital in-line holographic microscopy for high-resolution lensless biological imaging,” J. Biomed. Opt. 15(4), 046027 (2010).
[Crossref] [PubMed]

Montfort, F.

Mosk, A. P.

A. P. Mosk, A. Lagendijk, G. Lerosey, and M. Fink, “Controlling waves in space and time for imaging and focusing in complex media,” Nat. Photonics 6(5), 283–292 (2012).
[Crossref]

Mudanyali, O.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Nam, M.-H.

M. Roy, G. Jin, D. Seo, M.-H. Nam, and S. Seo, “A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique,” Sens. Actuators B Chem. 201, 321–328 (2014).
[Crossref]

Nelson, B. J.

Y. Sun, S. Duthaler, and B. J. Nelson, “Autofocusing in computer microscopy: selecting the optimal focus algorithm,” Microsc. Res. Tech. 65(3), 139–149 (2004).
[Crossref] [PubMed]

Oh, C.

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Oh, S.

M. Roy, D. Seo, S. Oh, J.-W. Yang, and S. Seo, “A review of recent progress in lens-free imaging and sensing,” Biosens. Bioelectron. 88, 130–143 (2017).
[Crossref] [PubMed]

Ozcan, A.

A. Greenbaum, U. Sikora, and A. Ozcan, “Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging,” Lab Chip 12(7), 1242–1245 (2012).
[Crossref] [PubMed]

A. Greenbaum and A. Ozcan, “Maskless imaging of dense samples using pixel super-resolution based multi-height lensfree on-chip microscopy,” Opt. Express 20(3), 3129–3143 (2012).
[Crossref] [PubMed]

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

S. O. Isikman, W. Bishara, H. Zhu, and A. Ozcan, “Optofluidic tomography on a chip,” Appl. Phys. Lett. 98(16), 161109 (2011).
[Crossref] [PubMed]

W. Bishara, T.-W. Su, A. F. Coskun, and A. Ozcan, “Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution,” Opt. Express 18(11), 11181–11191 (2010).
[Crossref] [PubMed]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

T.-W. Su, S. O. Isikman, W. Bishara, D. Tseng, A. Erlinger, and A. Ozcan, “Multi-angle lensless digital holography for depth resolved imaging on a chip,” Opt. Express 18(9), 9690–9711 (2010).
[Crossref] [PubMed]

S. Seo, T.-W. Su, D. K. Tseng, A. Erlinger, and A. Ozcan, “Lensfree holographic imaging for on-chip cytometry and diagnostics,” Lab Chip 9(6), 777–787 (2009).
[Crossref] [PubMed]

Oztoprak, C.

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Pan, F.

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

Piano, E.

Pontiggia, C.

Qu, W.

W. Qu, O. C. Chee, Y. Yu, and A. Asundi, “Recording and reconstruction of digital Gabor hologram,” Optik-Int. J. Light Electron Opt. 121(23), 2179–2184 (2010).
[Crossref]

Repetto, L.

Rong, L.

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

Roy, M.

M. Roy, D. Seo, S. Oh, J.-W. Yang, and S. Seo, “A review of recent progress in lens-free imaging and sensing,” Biosens. Bioelectron. 88, 130–143 (2017).
[Crossref] [PubMed]

M. Roy, G. Jin, D. Seo, M.-H. Nam, and S. Seo, “A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique,” Sens. Actuators B Chem. 201, 321–328 (2014).
[Crossref]

Schnars, U.

U. Schnars and W. P. Jüptner, “Digital recording and numerical reconstruction of holograms,” Meas. Sci. Technol. 13(9), R85–R101 (2002).
[Crossref]

U. Schnars and W. Jüptner, “Direct recording of holograms by a CCD target and numerical reconstruction,” Appl. Opt. 33(2), 179–181 (1994).
[Crossref] [PubMed]

Schockaert, C.

Sencan, I.

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Seo, D.

M. Roy, D. Seo, S. Oh, J.-W. Yang, and S. Seo, “A review of recent progress in lens-free imaging and sensing,” Biosens. Bioelectron. 88, 130–143 (2017).
[Crossref] [PubMed]

M. Roy, G. Jin, D. Seo, M.-H. Nam, and S. Seo, “A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique,” Sens. Actuators B Chem. 201, 321–328 (2014).
[Crossref]

Seo, S.

M. Roy, D. Seo, S. Oh, J.-W. Yang, and S. Seo, “A review of recent progress in lens-free imaging and sensing,” Biosens. Bioelectron. 88, 130–143 (2017).
[Crossref] [PubMed]

M. Roy, G. Jin, D. Seo, M.-H. Nam, and S. Seo, “A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique,” Sens. Actuators B Chem. 201, 321–328 (2014).
[Crossref]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

S. Seo, T.-W. Su, D. K. Tseng, A. Erlinger, and A. Ozcan, “Lensfree holographic imaging for on-chip cytometry and diagnostics,” Lab Chip 9(6), 777–787 (2009).
[Crossref] [PubMed]

Sheng, J.

Sikora, U.

A. Greenbaum, U. Sikora, and A. Ozcan, “Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging,” Lab Chip 12(7), 1242–1245 (2012).
[Crossref] [PubMed]

Song, J.-I.

Y.-S. Bae, J.-I. Song, and D. Y. Kim, “Volumetric reconstruction of Brownian motion of a micrometer-size bead in water,” Opt. Commun. 309, 291–297 (2013).
[Crossref]

Stamnes, J. J.

Su, T.-W.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

W. Bishara, T.-W. Su, A. F. Coskun, and A. Ozcan, “Lensfree on-chip microscopy over a wide field-of-view using pixel super-resolution,” Opt. Express 18(11), 11181–11191 (2010).
[Crossref] [PubMed]

T.-W. Su, S. O. Isikman, W. Bishara, D. Tseng, A. Erlinger, and A. Ozcan, “Multi-angle lensless digital holography for depth resolved imaging on a chip,” Opt. Express 18(9), 9690–9711 (2010).
[Crossref] [PubMed]

S. Seo, T.-W. Su, D. K. Tseng, A. Erlinger, and A. Ozcan, “Lensfree holographic imaging for on-chip cytometry and diagnostics,” Lab Chip 9(6), 777–787 (2009).
[Crossref] [PubMed]

Sun, Y.

Y. Sun, S. Duthaler, and B. J. Nelson, “Autofocusing in computer microscopy: selecting the optimal focus algorithm,” Microsc. Res. Tech. 65(3), 139–149 (2004).
[Crossref] [PubMed]

Tseng, D.

T.-W. Su, S. O. Isikman, W. Bishara, D. Tseng, A. Erlinger, and A. Ozcan, “Multi-angle lensless digital holography for depth resolved imaging on a chip,” Opt. Express 18(9), 9690–9711 (2010).
[Crossref] [PubMed]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

Tseng, D. K.

S. Seo, T.-W. Su, D. K. Tseng, A. Erlinger, and A. Ozcan, “Lensfree holographic imaging for on-chip cytometry and diagnostics,” Lab Chip 9(6), 777–787 (2009).
[Crossref] [PubMed]

Upatnieks, J.

Verrier, N.

von Bally, G.

Wang, D.

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

Wang, H.

L. Ma, H. Wang, Y. Li, and H. Jin, “Numerical reconstruction of digital holograms for three-dimensional shape measurement,” J. Opt. A 6(4), 396–400 (2004).
[Crossref]

Xiao, W.

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

Xu, W.

Xue, L.

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

Yamaguchi, I.

Yang, C.

G. Zheng, S. A. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, “The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proc. Natl. Acad. Sci. U.S.A. 108(41), 16889–16894 (2011).
[Crossref] [PubMed]

Yang, J.-W.

M. Roy, D. Seo, S. Oh, J.-W. Yang, and S. Seo, “A review of recent progress in lens-free imaging and sensing,” Biosens. Bioelectron. 88, 130–143 (2017).
[Crossref] [PubMed]

Yang, W.

Yaroslavsky, L. P.

Yourassowsky, C.

Yu, X.

X. Yu, J. Hong, C. Liu, and M. K. Kim, “Review of digital holographic microscopy for three-dimensional profiling and tracking,” Opt. Eng. 53(11), 112306 (2014).
[Crossref]

Yu, Y.

W. Qu, O. C. Chee, Y. Yu, and A. Asundi, “Recording and reconstruction of digital Gabor hologram,” Optik-Int. J. Light Electron Opt. 121(23), 2179–2184 (2010).
[Crossref]

Zalevsky, Z.

V. Micó and Z. Zalevsky, “Superresolved digital in-line holographic microscopy for high-resolution lensless biological imaging,” J. Biomed. Opt. 15(4), 046027 (2010).
[Crossref] [PubMed]

Zhang, F.

Zheng, G.

G. Zheng, S. A. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, “The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proc. Natl. Acad. Sci. U.S.A. 108(41), 16889–16894 (2011).
[Crossref] [PubMed]

Zhu, H.

S. O. Isikman, W. Bishara, H. Zhu, and A. Ozcan, “Optofluidic tomography on a chip,” Appl. Phys. Lett. 98(16), 161109 (2011).
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Am. J. Phys. (1)

J. E. Harvey, “Fourier treatment of near‐field scalar diffraction theory,” Am. J. Phys. 47(11), 974–980 (1979).
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Appl. Opt. (6)

Appl. Phys. Lett. (1)

S. O. Isikman, W. Bishara, H. Zhu, and A. Ozcan, “Optofluidic tomography on a chip,” Appl. Phys. Lett. 98(16), 161109 (2011).
[Crossref] [PubMed]

Biosens. Bioelectron. (1)

M. Roy, D. Seo, S. Oh, J.-W. Yang, and S. Seo, “A review of recent progress in lens-free imaging and sensing,” Biosens. Bioelectron. 88, 130–143 (2017).
[Crossref] [PubMed]

J. Biomed. Opt. (1)

V. Micó and Z. Zalevsky, “Superresolved digital in-line holographic microscopy for high-resolution lensless biological imaging,” J. Biomed. Opt. 15(4), 046027 (2010).
[Crossref] [PubMed]

J. Opt. (1)

B. K. Chen, T.-Y. Chen, S. G. Hung, S.-L. Huang, and J.-Y. Lin, “Twin image removal in digital in-line holography based on iterative inter-projections,” J. Opt. 18(6), 065602 (2016).
[Crossref]

J. Opt. A (1)

L. Ma, H. Wang, Y. Li, and H. Jin, “Numerical reconstruction of digital holograms for three-dimensional shape measurement,” J. Opt. A 6(4), 396–400 (2004).
[Crossref]

J. Opt. Soc. Am. (3)

J. Opt. Soc. Am. A (1)

Lab Chip (3)

A. Greenbaum, U. Sikora, and A. Ozcan, “Field-portable wide-field microscopy of dense samples using multi-height pixel super-resolution based lensfree imaging,” Lab Chip 12(7), 1242–1245 (2012).
[Crossref] [PubMed]

O. Mudanyali, D. Tseng, C. Oh, S. O. Isikman, I. Sencan, W. Bishara, C. Oztoprak, S. Seo, B. Khademhosseini, and A. Ozcan, “Compact, light-weight and cost-effective microscope based on lensless incoherent holography for telemedicine applications,” Lab Chip 10(11), 1417–1428 (2010).
[Crossref] [PubMed]

S. Seo, T.-W. Su, D. K. Tseng, A. Erlinger, and A. Ozcan, “Lensfree holographic imaging for on-chip cytometry and diagnostics,” Lab Chip 9(6), 777–787 (2009).
[Crossref] [PubMed]

Meas. Sci. Technol. (1)

U. Schnars and W. P. Jüptner, “Digital recording and numerical reconstruction of holograms,” Meas. Sci. Technol. 13(9), R85–R101 (2002).
[Crossref]

Microsc. Res. Tech. (1)

Y. Sun, S. Duthaler, and B. J. Nelson, “Autofocusing in computer microscopy: selecting the optimal focus algorithm,” Microsc. Res. Tech. 65(3), 139–149 (2004).
[Crossref] [PubMed]

Nat. Methods (1)

A. Greenbaum, W. Luo, T.-W. Su, Z. Göröcs, L. Xue, S. O. Isikman, A. F. Coskun, O. Mudanyali, and A. Ozcan, “Imaging without lenses: achievements and remaining challenges of wide-field on-chip microscopy,” Nat. Methods 9(9), 889–895 (2012).
[Crossref] [PubMed]

Nat. Photonics (1)

A. P. Mosk, A. Lagendijk, G. Lerosey, and M. Fink, “Controlling waves in space and time for imaging and focusing in complex media,” Nat. Photonics 6(5), 283–292 (2012).
[Crossref]

Nature (1)

D. Gabor, “A new microscopic principle,” Nature 161(4098), 777–778 (1948).
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Opt. Commun. (1)

Y.-S. Bae, J.-I. Song, and D. Y. Kim, “Volumetric reconstruction of Brownian motion of a micrometer-size bead in water,” Opt. Commun. 309, 291–297 (2013).
[Crossref]

Opt. Eng. (1)

X. Yu, J. Hong, C. Liu, and M. K. Kim, “Review of digital holographic microscopy for three-dimensional profiling and tracking,” Opt. Eng. 53(11), 112306 (2014).
[Crossref]

Opt. Express (5)

Opt. Lasers Eng. (1)

L. Rong, Y. Li, S. Liu, W. Xiao, F. Pan, and D. Wang, “Iterative solution to twin image problem in in-line digital holography,” Opt. Lasers Eng. 51(5), 553–559 (2013).
[Crossref]

Opt. Lett. (4)

Optik-Int. J. Light Electron Opt. (1)

W. Qu, O. C. Chee, Y. Yu, and A. Asundi, “Recording and reconstruction of digital Gabor hologram,” Optik-Int. J. Light Electron Opt. 121(23), 2179–2184 (2010).
[Crossref]

Phys. Rev. Lett. (1)

T. Latychevskaia and H.-W. Fink, “Solution to the twin image problem in holography,” Phys. Rev. Lett. 98(23), 233901 (2007).
[Crossref] [PubMed]

Proc. Natl. Acad. Sci. U.S.A. (1)

G. Zheng, S. A. Lee, Y. Antebi, M. B. Elowitz, and C. Yang, “The ePetri dish, an on-chip cell imaging platform based on subpixel perspective sweeping microscopy (SPSM),” Proc. Natl. Acad. Sci. U.S.A. 108(41), 16889–16894 (2011).
[Crossref] [PubMed]

Sens. Actuators B Chem. (1)

M. Roy, G. Jin, D. Seo, M.-H. Nam, and S. Seo, “A simple and low-cost device performing blood cell counting based on lens-free shadow imaging technique,” Sens. Actuators B Chem. 201, 321–328 (2014).
[Crossref]

Other (5)

A. Ayoub, P. Divós, S. Tóth, and S. Tõkés, “Software Algorithm to Reconstruct 2D Images from Recorded 3D In-Line DHM Holograms,” Computer and Automation Research Institute 5 (2006).

T. M. Kreis, M. Adams, and W. P. Jüptner, “Methods of digital holography: a comparison,” in Lasers and Optics in Manufacturing III (International Society for Optics and Photonics, 1997), pp. 224–233.

U. Schnars and W. Jueptner, Digital Holography: Digital Hologram Recording, Numerical Reconstruction, and Related Techniques (Springer Science & Business Media, 2005).

J. W. Goodman, Introduction to Fourier Optics (Roberts and Company Publishers, 2005).

M. K. Kim, “Principles and techniques of digital holographic microscopy,” J. Photonics Energy, 018005 (2010).
[Crossref]

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Figures (7)

Fig. 1
Fig. 1

Standard DIHM setup.

Fig. 2
Fig. 2

(a) A measured hologram, and (b) its best reconstructed image for a USAF 1951 target.

Fig. 3
Fig. 3

The location of an image (−zi, xi) when the positions of a light source (−zs, 0) and an object (−zo, xo) are given in DIHM.

Fig. 4
Fig. 4

(a) Relative percentage error in the calculated axial image position zi from the real object position zo defined in Eq. (8) for various values of zs and zo. (b) Relative error of zi as a function of zo when the distance between a light source and the detector array zs is 15, 20, 25, and 30 mm.

Fig. 5
Fig. 5

(a) DIHM setup to obtain holograms with various different object-to-detector distances. (b) Calculated axial positions by the ASM method and their corrected axial positions for different sample positions.

Fig. 6
Fig. 6

(a) DIHM setup to measure the 3D positions of hundreds of microspheres on a tilted microscope slide glass. (b) Hologram taken by the CMOS sensor. (c) Reconstructed image on a horizontal image plane of z = 6.2 mm.

Fig. 7
Fig. 7

(a) 3D distribution of reconstructed microbeads (top figure) calculated from a measured hologram by using an ASM algorithm, and its corrected distribution by our proposed scheme (bottom figure). (b) A side view of Fig. 7(a).

Equations (9)

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G(z, ƒ x , ƒ y )}=exp(ikz 1 λ 2 ƒ x 2 λ 2 ƒ y 2 )
R(z,x,y)= 1 {{H(0,x,y)}×G(z, f x , f y )}.
E s (0,x,y)=exp( ik z s 2 + x 2 + y 2 )exp(ik z s )exp( ik x 2 + y 2 2 z s )
E o (0,x,y)exp(ik z o )exp( ik (x x o ) 2 + (y y o ) 2 2 z o )
E s * E o =exp[ ik( z o z s ) ]exp ik{ (x x o ) 2 + (y y o ) 2 2 z o x 2 y 2 2 z o } .
E s * E o =exp[ ik( z o z s ) ( x o 2 + y o 2 ) 2 z o (1M) ]exp ik{ (x x i ) 2 + (y y i ) 2 2 z i }
1 z i ( 1 z o 1 z s )
M( z i z o )=( x i x o )
Error( z i z o z o )×100[ % ]

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