Abstract

Polarization-sensitive optical coherence tomography (PS-OCT) is a functional OCT providing both structural and birefringent information of the sample, and it has been applied to the studies of various organs having polarization properties. Fiber-based PS-OCT is sensitive to specular reflection from the sample surface, because signal saturation due to the strong specular reflection can make the polarization measurement difficult. We developed a dark-field PS-OCT which can avoid the specular reflection problem. Dark-field PS-OCT was implemented by adapting a hybrid method of Bessel-beam illumination and Gaussian-beam detection, and a PS-OCT method based on passive delay unit (PDU). The new system was characterized in comparison with the conventional Gaussian-beam based method in both polarization components and various samples including the human skin. Dark-field PS-OCT performed as good as the conventional PS-OCT without the specular reflection artifact. Dark-field PS-OCT may be useful in practical situations where the specular reflection is unavoidable.

© 2015 Optical Society of America

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    [Crossref] [PubMed]
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2015 (1)

2014 (2)

2013 (4)

2012 (6)

B. Baumann, W. Choi, B. Potsaid, D. Huang, J. S. Duker, and J. G. Fujimoto, “Swept source/Fourier domain polarization sensitive optical coherence tomography with a passive polarization delay unit,” Opt. Express 20(9), 10229–10241 (2012).
[PubMed]

N. Weber, D. Spether, A. Seifert, and H. Zappe, “Highly compact imaging using Bessel beams generated by ultraminiaturized multi-micro-axicon systems,” J. Opt. Soc. Am. A 29(5), 808–816 (2012).
[Crossref] [PubMed]

Y. Lim, Y. J. Hong, L. Duan, M. Yamanari, and Y. Yasuno, “Passive component based multifunctional Jones matrix swept source optical coherence tomography for Doppler and polarization imaging,” Opt. Lett. 37(11), 1958–1960 (2012).
[Crossref] [PubMed]

C. Blatter, J. Weingast, A. Alex, B. Grajciar, W. Wieser, W. Drexler, R. Huber, and R. A. Leitgeb, “In situ structural and microangiographic assessment of human skin lesions with high-speed OCT,” Biomed. Opt. Express 3(10), 2636–2646 (2012).
[Crossref] [PubMed]

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

T. Bolmont, A. Bouwens, C. Pache, M. Dimitrov, C. Berclaz, M. Villiger, B. M. Wegenast-Braun, T. Lasser, and P. C. Fraering, “Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy,” J. Neurosci. 32(42), 14548–14556 (2012).
[Crossref] [PubMed]

2011 (4)

2010 (2)

M. Villiger, C. Pache, and T. Lasser, “Dark-field optical coherence microscopy,” Opt. Lett. 35(20), 3489–3491 (2010).
[Crossref] [PubMed]

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

2009 (2)

M. Villiger, J. Goulley, M. Friedrich, A. Grapin-Botton, P. Meda, T. Lasser, and R. A. Leitgeb, “In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy,” Diabetologia 52(8), 1599–1607 (2009).
[Crossref] [PubMed]

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

2008 (7)

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008).
[Crossref] [PubMed]

M. Yamanari, S. Makita, and Y. Yasuno, “Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation,” Opt. Express 16(8), 5892–5906 (2008).
[Crossref] [PubMed]

W. Y. Oh, B. J. Vakoc, S. H. Yun, G. J. Tearney, and B. E. Bouma, “Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation,” Opt. Lett. 33(12), 1330–1332 (2008).
[Crossref] [PubMed]

K. S. Lee and J. P. Rolland, “Bessel beam spectral-domain high-resolution optical coherence tomography with micro-optic axicon providing extended focusing range,” Opt. Lett. 33(15), 1696–1698 (2008).
[Crossref] [PubMed]

O. Brzobohatý, T. Cizmár, and P. Zemánek, “High quality quasi-Bessel beam generated by round-tip axicon,” Opt. Express 16(17), 12688–12700 (2008).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008).
[Crossref] [PubMed]

2007 (2)

W. C. Kuo, N. K. Chou, C. Chou, C. M. Lai, H. J. Huang, S. S. Wang, and J. J. Shyu, “Polarization-sensitive optical coherence tomography for imaging human atherosclerosis,” Appl. Opt. 46(13), 2520–2527 (2007).
[Crossref] [PubMed]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

2006 (1)

2005 (2)

2004 (10)

M. Wojtkowski, V. Srinivasan, T. Ko, J. Fujimoto, A. Kowalczyk, and J. Duker, “Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation,” Opt. Express 12(11), 2404–2422 (2004).
[Crossref] [PubMed]

B. Cense, N. Nassif, T. Chen, M. Pierce, S. H. Yun, B. Park, B. Bouma, G. Tearney, and J. de Boer, “Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography,” Opt. Express 12(11), 2435–2447 (2004).
[Crossref] [PubMed]

M. Pircher, E. Goetzinger, R. Leitgeb, and C. Hitzenberger, “Three dimensional polarization sensitive OCT of human skin in vivo,” Opt. Express 12(14), 3236–3244 (2004).
[Crossref] [PubMed]

M. Todorović, S. Jiao, L. V. Wang, and G. Stoica, “Determination of local polarization properties of biological samples in the presence of diattenuation by use of Mueller optical coherence tomography,” Opt. Lett. 29(20), 2402–2404 (2004).
[Crossref] [PubMed]

B. Hyle Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components,” Opt. Lett. 29(21), 2512–2514 (2004).
[Crossref] [PubMed]

M. Pircher, E. Götzinger, R. Leitgeb, H. Sattmann, O. Findl, and C. K. Hitzenberger, “Imaging of polarization properties of human retina in vivo with phase resolved transversal PS-OCT,” Opt. Express 12(24), 5940–5951 (2004).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, and J. F. de Boer, “Comment on “Optical-fiber-based Mueller optical coherence tomography”,” Opt. Lett. 29(24), 2873–2877 (2004).
[Crossref] [PubMed]

M. C. Pierce, R. L. Sheridan, B. Hyle Park, B. Cense, and J. F. de Boer, “Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography,” Burns 30(6), 511–517 (2004).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9(1), 94–102 (2004).
[Crossref] [PubMed]

V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

2003 (4)

2002 (4)

Z. Ding, H. Ren, Y. Zhao, J. S. Nelson, and Z. Chen, “High-resolution optical coherence tomography over a large depth range with an axicon lens,” Opt. Lett. 27(4), 243–245 (2002).
[Crossref] [PubMed]

M. C. Pierce, B. Hyle Park, B. Cense, and J. F. de Boer, “Simultaneous intensity, birefringence, and flow measurements with high-speed fiber-based optical coherence tomography,” Opt. Lett. 27(17), 1534–1536 (2002).
[Crossref] [PubMed]

J. F. de Boer and T. E. Milner, “Review of polarization sensitive optical coherence tomography and Stokes vector determination,” J. Biomed. Opt. 7(3), 359–371 (2002).
[Crossref] [PubMed]

S. Jiao and L. V. Wang, “Jones-matrix imaging of biological tissues with quadruple-channel optical coherence tomography,” J. Biomed. Opt. 7(3), 350–358 (2002).
[Crossref] [PubMed]

2001 (1)

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[Crossref] [PubMed]

2000 (1)

1999 (1)

1991 (1)

Ahlers, C.

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008).
[Crossref] [PubMed]

Alex, A.

Bachmann, A. H.

Baumann, B.

Berclaz, C.

A. Bouwens, T. Bolmont, D. Szlag, C. Berclaz, and T. Lasser, “Quantitative cerebral blood flow imaging with extended-focus optical coherence microscopy,” Opt. Lett. 39(1), 37–40 (2014).
[Crossref] [PubMed]

T. Bolmont, A. Bouwens, C. Pache, M. Dimitrov, C. Berclaz, M. Villiger, B. M. Wegenast-Braun, T. Lasser, and P. C. Fraering, “Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy,” J. Neurosci. 32(42), 14548–14556 (2012).
[Crossref] [PubMed]

Biedermann, B. R.

Blatter, C.

Bolmont, T.

Bouma, B.

Bouma, B. E.

M. Villiger, E. Z. Zhang, S. K. Nadkarni, W. Y. Oh, B. J. Vakoc, and B. E. Bouma, “Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging,” Opt. Express 21(14), 16353–16369 (2013).
[Crossref] [PubMed]

E. Z. Zhang, W. Y. Oh, M. L. Villiger, L. Chen, B. E. Bouma, and B. J. Vakoc, “Numerical compensation of system polarization mode dispersion in polarization-sensitive optical coherence tomography,” Opt. Express 21(1), 1163–1180 (2013).
[Crossref] [PubMed]

M. Villiger, E. Z. Zhang, S. Nadkarni, W. Y. Oh, B. E. Bouma, and B. J. Vakoc, “Artifacts in polarization-sensitive optical coherence tomography caused by polarization mode dispersion,” Opt. Lett. 38(6), 923–925 (2013).
[Crossref] [PubMed]

W. Y. Oh, B. J. Vakoc, S. H. Yun, G. J. Tearney, and B. E. Bouma, “Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation,” Opt. Lett. 33(12), 1330–1332 (2008).
[Crossref] [PubMed]

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008).
[Crossref] [PubMed]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

Bouwens, A.

Braaf, B.

Bressner, J. E.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

Brzobohatý, O.

Cense, B.

Chen, L.

Chen, T.

Chen, Z.

Choi, W.

Chou, C.

Chou, N. K.

Cizmár, T.

de Boer, J.

de Boer, J. F.

B. Braaf, K. A. Vermeer, M. de Groot, K. V. Vienola, and J. F. de Boer, “Fiber-based polarization-sensitive OCT of the human retina with correction of system polarization distortions,” Biomed. Opt. Express 5(8), 2736–2758 (2014).
[Crossref] [PubMed]

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

K. H. Kim, B. H. Park, Y. Tu, T. Hasan, B. Lee, J. Li, and J. F. de Boer, “Polarization-sensitive optical frequency domain imaging based on unpolarized light,” Opt. Express 19(2), 552–561 (2011).
[Crossref] [PubMed]

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008).
[Crossref] [PubMed]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography,” Opt. Lett. 30(19), 2587–2589 (2005).
[Crossref] [PubMed]

M. C. Pierce, R. L. Sheridan, B. Hyle Park, B. Cense, and J. F. de Boer, “Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography,” Burns 30(6), 511–517 (2004).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, and J. F. de Boer, “Comment on “Optical-fiber-based Mueller optical coherence tomography”,” Opt. Lett. 29(24), 2873–2877 (2004).
[Crossref] [PubMed]

B. Hyle Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components,” Opt. Lett. 29(21), 2512–2514 (2004).
[Crossref] [PubMed]

J. F. de Boer and T. E. Milner, “Review of polarization sensitive optical coherence tomography and Stokes vector determination,” J. Biomed. Opt. 7(3), 359–371 (2002).
[Crossref] [PubMed]

M. C. Pierce, B. Hyle Park, B. Cense, and J. F. de Boer, “Simultaneous intensity, birefringence, and flow measurements with high-speed fiber-based optical coherence tomography,” Opt. Lett. 27(17), 1534–1536 (2002).
[Crossref] [PubMed]

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[Crossref] [PubMed]

C. E. Saxer, J. F. de Boer, B. H. Park, Y. Zhao, Z. Chen, and J. S. Nelson, “High-speed fiber based polarization-sensitive optical coherence tomography of in vivo human skin,” Opt. Lett. 25(18), 1355–1357 (2000).
[Crossref] [PubMed]

J. F. de Boer, T. E. Milner, and J. S. Nelson, “Determination of the depth-resolved Stokes parameters of light backscattered from turbid media by use of polarization-sensitive optical coherence tomography,” Opt. Lett. 24(5), 300–302 (1999).
[Crossref] [PubMed]

de Groot, M.

Desjardins, A. E.

Dimitrov, M.

T. Bolmont, A. Bouwens, C. Pache, M. Dimitrov, C. Berclaz, M. Villiger, B. M. Wegenast-Braun, T. Lasser, and P. C. Fraering, “Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy,” J. Neurosci. 32(42), 14548–14556 (2012).
[Crossref] [PubMed]

Ding, Z.

Drexler, W.

Duan, L.

Duker, J.

Duker, J. S.

Eigenwillig, C. M.

Fercher, A. F.

E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9(1), 94–102 (2004).
[Crossref] [PubMed]

Findl, O.

Fraering, P. C.

T. Bolmont, A. Bouwens, C. Pache, M. Dimitrov, C. Berclaz, M. Villiger, B. M. Wegenast-Braun, T. Lasser, and P. C. Fraering, “Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy,” J. Neurosci. 32(42), 14548–14556 (2012).
[Crossref] [PubMed]

Friedrich, M.

M. Villiger, J. Goulley, M. Friedrich, A. Grapin-Botton, P. Meda, T. Lasser, and R. A. Leitgeb, “In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy,” Diabetologia 52(8), 1599–1607 (2009).
[Crossref] [PubMed]

Fujimoto, J.

Fujimoto, J. G.

Geitzenauer, W.

Goetzinger, E.

Golbaz, I.

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

Götzinger, E.

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, and C. K. Hitzenberger, “High speed spectral domain polarization sensitive optical coherence tomography of the human retina,” Opt. Express 13(25), 10217–10229 (2005).
[Crossref] [PubMed]

M. Pircher, E. Götzinger, R. Leitgeb, H. Sattmann, O. Findl, and C. K. Hitzenberger, “Imaging of polarization properties of human retina in vivo with phase resolved transversal PS-OCT,” Opt. Express 12(24), 5940–5951 (2004).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9(1), 94–102 (2004).
[Crossref] [PubMed]

Goulley, J.

M. Villiger, J. Goulley, M. Friedrich, A. Grapin-Botton, P. Meda, T. Lasser, and R. A. Leitgeb, “In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy,” Diabetologia 52(8), 1599–1607 (2009).
[Crossref] [PubMed]

Grajciar, B.

Grapin-Botton, A.

M. Villiger, J. Goulley, M. Friedrich, A. Grapin-Botton, P. Meda, T. Lasser, and R. A. Leitgeb, “In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy,” Diabetologia 52(8), 1599–1607 (2009).
[Crossref] [PubMed]

Halpern, E.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

Hasan, T.

Hitzenberger, C.

Hitzenberger, C. K.

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, and C. K. Hitzenberger, “High speed spectral domain polarization sensitive optical coherence tomography of the human retina,” Opt. Express 13(25), 10217–10229 (2005).
[Crossref] [PubMed]

M. Pircher, E. Götzinger, R. Leitgeb, H. Sattmann, O. Findl, and C. K. Hitzenberger, “Imaging of polarization properties of human retina in vivo with phase resolved transversal PS-OCT,” Opt. Express 12(24), 5940–5951 (2004).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9(1), 94–102 (2004).
[Crossref] [PubMed]

Hong, Y. J.

Houser, S. L.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

Huang, D.

Huang, H. J.

Huber, R.

Hyle Park, B.

Iftimia, N.

Jiao, S.

Kamensky, V. A.

V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

Kawabata, K.

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Kim, K. H.

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

K. H. Kim, B. H. Park, Y. Tu, T. Hasan, B. Lee, J. Li, and J. F. de Boer, “Polarization-sensitive optical frequency domain imaging based on unpolarized light,” Opt. Express 19(2), 552–561 (2011).
[Crossref] [PubMed]

Ko, T.

Kowalczyk, A.

Kuo, W. C.

Kuranov, R. V.

V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

Kutis, I.

V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

Lai, C. M.

Lasser, T.

Lee, B.

Lee, K. S.

Leitgeb, R.

Leitgeb, R. A.

Li, J.

Lim, Y.

Lydon, M.

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

Maguluri, G.

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

Makita, S.

Matsumoto, M.

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Meda, P.

M. Villiger, J. Goulley, M. Friedrich, A. Grapin-Botton, P. Meda, T. Lasser, and R. A. Leitgeb, “In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy,” Diabetologia 52(8), 1599–1607 (2009).
[Crossref] [PubMed]

Michels, S.

Milner, T. E.

Miyazawa, A.

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Myakov, A. V.

V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

Nadkarni, S.

Nadkarni, S. K.

M. Villiger, E. Z. Zhang, S. K. Nadkarni, W. Y. Oh, B. J. Vakoc, and B. E. Bouma, “Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging,” Opt. Express 21(14), 16353–16369 (2013).
[Crossref] [PubMed]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

Nakagawa, N.

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Nassif, N.

Nelson, J. S.

Oh, W. Y.

Pache, C.

T. Bolmont, A. Bouwens, C. Pache, M. Dimitrov, C. Berclaz, M. Villiger, B. M. Wegenast-Braun, T. Lasser, and P. C. Fraering, “Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy,” J. Neurosci. 32(42), 14548–14556 (2012).
[Crossref] [PubMed]

M. Villiger, C. Pache, and T. Lasser, “Dark-field optical coherence microscopy,” Opt. Lett. 35(20), 3489–3491 (2010).
[Crossref] [PubMed]

Park, B.

Park, B. H.

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

K. H. Kim, B. H. Park, Y. Tu, T. Hasan, B. Lee, J. Li, and J. F. de Boer, “Polarization-sensitive optical frequency domain imaging based on unpolarized light,” Opt. Express 19(2), 552–561 (2011).
[Crossref] [PubMed]

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008).
[Crossref] [PubMed]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography,” Opt. Lett. 30(19), 2587–2589 (2005).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, and J. F. de Boer, “Comment on “Optical-fiber-based Mueller optical coherence tomography”,” Opt. Lett. 29(24), 2873–2877 (2004).
[Crossref] [PubMed]

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[Crossref] [PubMed]

C. E. Saxer, J. F. de Boer, B. H. Park, Y. Zhao, Z. Chen, and J. S. Nelson, “High-speed fiber based polarization-sensitive optical coherence tomography of in vivo human skin,” Opt. Lett. 25(18), 1355–1357 (2000).
[Crossref] [PubMed]

Pierce, M.

Pierce, M. C.

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography,” Opt. Lett. 30(19), 2587–2589 (2005).
[Crossref] [PubMed]

M. C. Pierce, R. L. Sheridan, B. Hyle Park, B. Cense, and J. F. de Boer, “Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography,” Burns 30(6), 511–517 (2004).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, and J. F. de Boer, “Comment on “Optical-fiber-based Mueller optical coherence tomography”,” Opt. Lett. 29(24), 2873–2877 (2004).
[Crossref] [PubMed]

B. Hyle Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components,” Opt. Lett. 29(21), 2512–2514 (2004).
[Crossref] [PubMed]

M. C. Pierce, B. Hyle Park, B. Cense, and J. F. de Boer, “Simultaneous intensity, birefringence, and flow measurements with high-speed fiber-based optical coherence tomography,” Opt. Lett. 27(17), 1534–1536 (2002).
[Crossref] [PubMed]

Pircher, M.

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, and C. K. Hitzenberger, “High speed spectral domain polarization sensitive optical coherence tomography of the human retina,” Opt. Express 13(25), 10217–10229 (2005).
[Crossref] [PubMed]

M. Pircher, E. Götzinger, R. Leitgeb, H. Sattmann, O. Findl, and C. K. Hitzenberger, “Imaging of polarization properties of human retina in vivo with phase resolved transversal PS-OCT,” Opt. Express 12(24), 5940–5951 (2004).
[Crossref] [PubMed]

M. Pircher, E. Goetzinger, R. Leitgeb, and C. Hitzenberger, “Three dimensional polarization sensitive OCT of human skin in vivo,” Opt. Express 12(14), 3236–3244 (2004).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9(1), 94–102 (2004).
[Crossref] [PubMed]

Potsaid, B.

Prager, F.

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

Ren, H.

Rolland, J. P.

Sakai, S.

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Sapozhnikova, V. V.

V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

Sattmann, H.

Saxer, C.

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[Crossref] [PubMed]

Saxer, C. E.

Schmidt-Erfurth, U.

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008).
[Crossref] [PubMed]

Schütze, C.

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

Seifert, A.

Sheridan, R.

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

Sheridan, R. L.

M. C. Pierce, R. L. Sheridan, B. Hyle Park, B. Cense, and J. F. de Boer, “Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography,” Burns 30(6), 511–517 (2004).
[Crossref] [PubMed]

Shishkov, M.

Shyu, J. J.

Snopova, L. B.

V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

Spether, D.

Srinivas, S. M.

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[Crossref] [PubMed]

Srinivasan, V.

Steinmann, L.

Sticker, M.

E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9(1), 94–102 (2004).
[Crossref] [PubMed]

Stoica, G.

Sugawara, T.

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Sugiyama, S.

Szkulmowski, M.

Szlag, D.

Tearney, G.

Tearney, G. J.

Todorovic, M.

Tu, Y.

Vakoc, B. J.

M. Villiger, E. Z. Zhang, S. Nadkarni, W. Y. Oh, B. E. Bouma, and B. J. Vakoc, “Artifacts in polarization-sensitive optical coherence tomography caused by polarization mode dispersion,” Opt. Lett. 38(6), 923–925 (2013).
[Crossref] [PubMed]

M. Villiger, E. Z. Zhang, S. K. Nadkarni, W. Y. Oh, B. J. Vakoc, and B. E. Bouma, “Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging,” Opt. Express 21(14), 16353–16369 (2013).
[Crossref] [PubMed]

E. Z. Zhang, W. Y. Oh, M. L. Villiger, L. Chen, B. E. Bouma, and B. J. Vakoc, “Numerical compensation of system polarization mode dispersion in polarization-sensitive optical coherence tomography,” Opt. Express 21(1), 1163–1180 (2013).
[Crossref] [PubMed]

E. Z. Zhang and B. J. Vakoc, “Polarimetry noise in fiber-based optical coherence tomography instrumentation,” Opt. Express 19(18), 16830–16842 (2011).
[Crossref] [PubMed]

W. Y. Oh, B. J. Vakoc, S. H. Yun, G. J. Tearney, and B. E. Bouma, “Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation,” Opt. Lett. 33(12), 1330–1332 (2008).
[Crossref] [PubMed]

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008).
[Crossref] [PubMed]

Vermeer, K. A.

Vienola, K. V.

Villiger, M.

Villiger, M. L.

Wang, L. V.

Wang, S. S.

Weber, N.

Wegenast-Braun, B. M.

T. Bolmont, A. Bouwens, C. Pache, M. Dimitrov, C. Berclaz, M. Villiger, B. M. Wegenast-Braun, T. Lasser, and P. C. Fraering, “Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy,” J. Neurosci. 32(42), 14548–14556 (2012).
[Crossref] [PubMed]

Weingast, J.

Whittaker, P.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

Wieser, W.

Wiggins, R. M. H. T. A.

Wojtkowski, M.

Yamanari, M.

Y. Lim, Y. J. Hong, L. Duan, M. Yamanari, and Y. Yasuno, “Passive component based multifunctional Jones matrix swept source optical coherence tomography for Doppler and polarization imaging,” Opt. Lett. 37(11), 1958–1960 (2012).
[Crossref] [PubMed]

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

M. Yamanari, S. Makita, and Y. Yasuno, “Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation,” Opt. Express 16(8), 5892–5906 (2008).
[Crossref] [PubMed]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Yasuno, Y.

Y. J. Hong, S. Makita, S. Sugiyama, and Y. Yasuno, “Optically buffered Jones-matrix-based multifunctional optical coherence tomography with polarization mode dispersion correction,” Biomed. Opt. Express 6(1), 225–243 (2015).
[Crossref] [PubMed]

Y. Lim, Y. J. Hong, L. Duan, M. Yamanari, and Y. Yasuno, “Passive component based multifunctional Jones matrix swept source optical coherence tomography for Doppler and polarization imaging,” Opt. Lett. 37(11), 1958–1960 (2012).
[Crossref] [PubMed]

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

M. Yamanari, S. Makita, and Y. Yasuno, “Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation,” Opt. Express 16(8), 5892–5906 (2008).
[Crossref] [PubMed]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Yatagai, T.

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

Yoon, S. J.

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

Yu, W.

Yun, S.

Yun, S. H.

Zappe, H.

Zemánek, P.

Zhang, E. Z.

Zhao, Y.

Appl. Opt. (1)

Biomed. Opt. Express (3)

Burns (1)

M. C. Pierce, R. L. Sheridan, B. Hyle Park, B. Cense, and J. F. de Boer, “Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography,” Burns 30(6), 511–517 (2004).
[Crossref] [PubMed]

Diabetologia (1)

M. Villiger, J. Goulley, M. Friedrich, A. Grapin-Botton, P. Meda, T. Lasser, and R. A. Leitgeb, “In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy,” Diabetologia 52(8), 1599–1607 (2009).
[Crossref] [PubMed]

Invest. Ophthalmol. Vis. Sci. (1)

C. Ahlers, E. Götzinger, M. Pircher, I. Golbaz, F. Prager, C. Schütze, B. Baumann, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 51(4), 2149–2157 (2010).
[Crossref] [PubMed]

J. Am. Coll. Cardiol. (1)

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[Crossref] [PubMed]

J. Biomed. Opt. (6)

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[Crossref] [PubMed]

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[Crossref] [PubMed]

K. H. Kim, M. C. Pierce, G. Maguluri, B. H. Park, S. J. Yoon, M. Lydon, R. Sheridan, and J. F. de Boer, “In vivo imaging of human burn injuries with polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 17(6), 066012 (2012).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, M. Sticker, A. F. Fercher, and C. K. Hitzenberger, “Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography,” J. Biomed. Opt. 9(1), 94–102 (2004).
[Crossref] [PubMed]

J. F. de Boer and T. E. Milner, “Review of polarization sensitive optical coherence tomography and Stokes vector determination,” J. Biomed. Opt. 7(3), 359–371 (2002).
[Crossref] [PubMed]

S. Jiao and L. V. Wang, “Jones-matrix imaging of biological tissues with quadruple-channel optical coherence tomography,” J. Biomed. Opt. 7(3), 350–358 (2002).
[Crossref] [PubMed]

J. Invest. Dermatol. (1)

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[Crossref] [PubMed]

J. Neurosci. (1)

T. Bolmont, A. Bouwens, C. Pache, M. Dimitrov, C. Berclaz, M. Villiger, B. M. Wegenast-Braun, T. Lasser, and P. C. Fraering, “Label-free imaging of cerebral β-amyloidosis with extended-focus optical coherence microscopy,” J. Neurosci. 32(42), 14548–14556 (2012).
[Crossref] [PubMed]

J. Opt. Soc. Am. A (2)

Nat. Biotechnol. (1)

J. G. Fujimoto, “Optical coherence tomography for ultrahigh resolution in vivo imaging,” Nat. Biotechnol. 21(11), 1361–1367 (2003).
[Crossref] [PubMed]

Opt. Express (18)

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008).
[Crossref] [PubMed]

M. Yamanari, S. Makita, and Y. Yasuno, “Polarization-sensitive swept-source optical coherence tomography with continuous source polarization modulation,” Opt. Express 16(8), 5892–5906 (2008).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, and C. K. Hitzenberger, “High speed spectral domain polarization sensitive optical coherence tomography of the human retina,” Opt. Express 13(25), 10217–10229 (2005).
[Crossref] [PubMed]

O. Brzobohatý, T. Cizmár, and P. Zemánek, “High quality quasi-Bessel beam generated by round-tip axicon,” Opt. Express 16(17), 12688–12700 (2008).
[Crossref] [PubMed]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008).
[Crossref] [PubMed]

S. Yun, G. Tearney, J. de Boer, N. Iftimia, and B. Bouma, “High-speed optical frequency-domain imaging,” Opt. Express 11(22), 2953–2963 (2003).
[Crossref] [PubMed]

M. Wojtkowski, V. Srinivasan, T. Ko, J. Fujimoto, A. Kowalczyk, and J. Duker, “Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation,” Opt. Express 12(11), 2404–2422 (2004).
[Crossref] [PubMed]

B. Cense, N. Nassif, T. Chen, M. Pierce, S. H. Yun, B. Park, B. Bouma, G. Tearney, and J. de Boer, “Ultrahigh-resolution high-speed retinal imaging using spectral-domain optical coherence tomography,” Opt. Express 12(11), 2435–2447 (2004).
[Crossref] [PubMed]

M. Pircher, E. Goetzinger, R. Leitgeb, and C. Hitzenberger, “Three dimensional polarization sensitive OCT of human skin in vivo,” Opt. Express 12(14), 3236–3244 (2004).
[Crossref] [PubMed]

B. Park, M. Pierce, B. Cense, and J. de Boer, “Real-time multi-functional optical coherence tomography,” Opt. Express 11(7), 782–793 (2003).
[Crossref] [PubMed]

M. Pircher, E. Götzinger, R. Leitgeb, H. Sattmann, O. Findl, and C. K. Hitzenberger, “Imaging of polarization properties of human retina in vivo with phase resolved transversal PS-OCT,” Opt. Express 12(24), 5940–5951 (2004).
[Crossref] [PubMed]

E. Z. Zhang, W. Y. Oh, M. L. Villiger, L. Chen, B. E. Bouma, and B. J. Vakoc, “Numerical compensation of system polarization mode dispersion in polarization-sensitive optical coherence tomography,” Opt. Express 21(1), 1163–1180 (2013).
[Crossref] [PubMed]

K. H. Kim, B. H. Park, Y. Tu, T. Hasan, B. Lee, J. Li, and J. F. de Boer, “Polarization-sensitive optical frequency domain imaging based on unpolarized light,” Opt. Express 19(2), 552–561 (2011).
[Crossref] [PubMed]

C. Blatter, B. Grajciar, C. M. Eigenwillig, W. Wieser, B. R. Biedermann, R. Huber, and R. A. Leitgeb, “Extended focus high-speed swept source OCT with self-reconstructive illumination,” Opt. Express 19(13), 12141–12155 (2011).
[Crossref] [PubMed]

E. Z. Zhang and B. J. Vakoc, “Polarimetry noise in fiber-based optical coherence tomography instrumentation,” Opt. Express 19(18), 16830–16842 (2011).
[Crossref] [PubMed]

B. Baumann, W. Choi, B. Potsaid, D. Huang, J. S. Duker, and J. G. Fujimoto, “Swept source/Fourier domain polarization sensitive optical coherence tomography with a passive polarization delay unit,” Opt. Express 20(9), 10229–10241 (2012).
[PubMed]

M. Villiger, E. Z. Zhang, S. K. Nadkarni, W. Y. Oh, B. J. Vakoc, and B. E. Bouma, “Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging,” Opt. Express 21(14), 16353–16369 (2013).
[Crossref] [PubMed]

A. Bouwens, D. Szlag, M. Szkulmowski, T. Bolmont, M. Wojtkowski, and T. Lasser, “Quantitative lateral and axial flow imaging with optical coherence microscopy and tomography,” Opt. Express 21(15), 17711–17729 (2013).
[PubMed]

Opt. Lett. (16)

A. Bouwens, T. Bolmont, D. Szlag, C. Berclaz, and T. Lasser, “Quantitative cerebral blood flow imaging with extended-focus optical coherence microscopy,” Opt. Lett. 39(1), 37–40 (2014).
[Crossref] [PubMed]

M. Villiger, E. Z. Zhang, S. Nadkarni, W. Y. Oh, B. E. Bouma, and B. J. Vakoc, “Artifacts in polarization-sensitive optical coherence tomography caused by polarization mode dispersion,” Opt. Lett. 38(6), 923–925 (2013).
[Crossref] [PubMed]

Y. Lim, Y. J. Hong, L. Duan, M. Yamanari, and Y. Yasuno, “Passive component based multifunctional Jones matrix swept source optical coherence tomography for Doppler and polarization imaging,” Opt. Lett. 37(11), 1958–1960 (2012).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, and J. F. de Boer, “Comment on “Optical-fiber-based Mueller optical coherence tomography”,” Opt. Lett. 29(24), 2873–2877 (2004).
[Crossref] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Optic axis determination accuracy for fiber-based polarization-sensitive optical coherence tomography,” Opt. Lett. 30(19), 2587–2589 (2005).
[Crossref] [PubMed]

S. Jiao, W. Yu, G. Stoica, and L. V. Wang, “Optical-fiber-based Mueller optical coherence tomography,” Opt. Lett. 28(14), 1206–1208 (2003).
[Crossref] [PubMed]

M. Todorović, S. Jiao, L. V. Wang, and G. Stoica, “Determination of local polarization properties of biological samples in the presence of diattenuation by use of Mueller optical coherence tomography,” Opt. Lett. 29(20), 2402–2404 (2004).
[Crossref] [PubMed]

B. Hyle Park, M. C. Pierce, B. Cense, and J. F. de Boer, “Jones matrix analysis for a polarization-sensitive optical coherence tomography system using fiber-optic components,” Opt. Lett. 29(21), 2512–2514 (2004).
[Crossref] [PubMed]

M. Villiger, C. Pache, and T. Lasser, “Dark-field optical coherence microscopy,” Opt. Lett. 35(20), 3489–3491 (2010).
[Crossref] [PubMed]

R. A. Leitgeb, M. Villiger, A. H. Bachmann, L. Steinmann, and T. Lasser, “Extended focus depth for Fourier domain optical coherence microscopy,” Opt. Lett. 31(16), 2450–2452 (2006).
[Crossref] [PubMed]

W. Y. Oh, B. J. Vakoc, S. H. Yun, G. J. Tearney, and B. E. Bouma, “Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation,” Opt. Lett. 33(12), 1330–1332 (2008).
[Crossref] [PubMed]

K. S. Lee and J. P. Rolland, “Bessel beam spectral-domain high-resolution optical coherence tomography with micro-optic axicon providing extended focusing range,” Opt. Lett. 33(15), 1696–1698 (2008).
[Crossref] [PubMed]

J. F. de Boer, T. E. Milner, and J. S. Nelson, “Determination of the depth-resolved Stokes parameters of light backscattered from turbid media by use of polarization-sensitive optical coherence tomography,” Opt. Lett. 24(5), 300–302 (1999).
[Crossref] [PubMed]

C. E. Saxer, J. F. de Boer, B. H. Park, Y. Zhao, Z. Chen, and J. S. Nelson, “High-speed fiber based polarization-sensitive optical coherence tomography of in vivo human skin,” Opt. Lett. 25(18), 1355–1357 (2000).
[Crossref] [PubMed]

Z. Ding, H. Ren, Y. Zhao, J. S. Nelson, and Z. Chen, “High-resolution optical coherence tomography over a large depth range with an axicon lens,” Opt. Lett. 27(4), 243–245 (2002).
[Crossref] [PubMed]

M. C. Pierce, B. Hyle Park, B. Cense, and J. F. de Boer, “Simultaneous intensity, birefringence, and flow measurements with high-speed fiber-based optical coherence tomography,” Opt. Lett. 27(17), 1534–1536 (2002).
[Crossref] [PubMed]

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V. V. Sapozhnikova, V. A. Kamensky, R. V. Kuranov, I. Kutis, L. B. Snopova, and A. V. Myakov, “In vivo visualization of Tradescantia leaf tissue and monitoring the physiological and morphological states under different water supply conditions using optical coherence tomography,” Planta 219(4), 601–609 (2004).
[Crossref] [PubMed]

Prog. Retin. Eye Res. (1)

M. Pircher, C. K. Hitzenberger, and U. Schmidt-Erfurth, “Polarization sensitive optical coherence tomography in the human eye,” Prog. Retin. Eye Res. 30(6), 431–451 (2011).
[Crossref] [PubMed]

Supplementary Material (5)

» Media 1: MOV (7872 KB)     
» Media 2: MOV (10300 KB)     
» Media 3: MOV (12684 KB)     
» Media 4: MOV (7477 KB)     
» Media 5: MOV (7440 KB)     

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Figures (8)

Fig. 1
Fig. 1 (a) System configuration of dark-field PS-OCT. Bessel-beam illumination and Gaussian-beam detection path for dark-field PS-OCT are depicted in gray and red respectively. Illumination and detection path of conventional PS-OCT used the detection path of dark-field PS-OCT. Optical path of conventional PS-OCT is represented by a broken line. (b) Scheme of the passive delay unit (Δz = 2.25 mm in air). PC: polarization controller, FBG: fiber Bragg grating, CM: collimator, CIR: fiber circulator, FC: fiber coupler, QWP: quarter wave plate, LP: linear polarizer, BS: non-polarizing beam splitter, PBS: polarizing beam splitter, PD: photodetector, PDD: polarization diverse detection, M: mirror, SM: scanning mirror, P: prism, L1-L5: Achromatic lens (f = 100 mm), L6: 5x OCT scan lens (EF = 36 mm).

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Fig. 2
Fig. 2 Images of microspheres (6 μm in diameter) by conventional setup (a, b) and dark-field setup (c, d) in the x-z and x-y planes respectively. Blue broken lines in the x-z plane images indicate the location of the x-y plane images. All scale bars are 300 μm.

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Fig. 3
Fig. 3 Cross-sectional OCT images of back of a human hand by using (a) conventional setup and (b) dark-field setup. (c) Mean intensity profiles of images (a) and (b) as a function of depth. All scale bars are 1 mm.

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Fig. 4
Fig. 4 Images of a plant leaf by conventional setup (a, c) and dark-field setup (b, d) in the x-z and x-y planes respectively. (Video clips of the x-z plane images are presented in media 1.) All scale bars are 1 mm.

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Fig. 5
Fig. 5 Polarimetric measurement of the conventional and dark-field PS-OCT systems (a) Double-pass phase retardation (DPPR) of the quarter wave plate (QWP) and (b) the optic axis of the polarizing film (PF) as a function of the sample rotation

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Fig. 6
Fig. 6 Rat skin images in the x-z plane by conventional and dark-field PS-OCTs. (a, b) and (c, d) are intensity and PS images by conventional PS-OCT (media 2) and dark-field PS-OCT (media 3) respectively. Red arrows indicate signal artifacts. All scale bars are 1 mm.

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Fig. 7
Fig. 7 Human skin images in the x-z plane by conventional and dark-field PS-OCTs. (a, b) and (c, d) are intensity and PS images by conventional PS-OCT (media 4) and dark-field PS-OCT (media 5) respectively. Red arrows indicate artifacts. All scale bars are 1 mm.

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Fig. 8
Fig. 8 Average accumulated phase retardation with depth by conventional and dark-field PS-OCT setup

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