Abstract

In this paper, we investigate detection characteristics of localized surface plasmon resonance biosensing based on a probabilistic Poisson distribution of target molecules. The model uses random nanoislands for localization of near-fields in three detection scenarios of non-specific, non-colocalized, and colocalized detection. Optical signatures were found to increase monotonically with target concentration and size regardless of the detection scenarios. The signatures were largest in colocalized detection of target interactions to localized fields, followed by non-colocalized and non-specific detection. The confidence interval was the narrowest in the colocalized detection due to the increased spatial certainty by localization. Based on the relative confidence interval, it was found that limit of detection can be enhanced by more than four orders of magnitude through colocalization.

© 2014 Optical Society of America

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Field-matter integral overlap to estimate the sensitivity of surface plasmon resonance biosensors

Wonju Lee and Donghyun Kim
J. Opt. Soc. Am. A 29(7) 1367-1376 (2012)

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2014 (6)

Y. Oh, W. Lee, Y. Kim, and D. Kim, “Self-aligned colocalization of 3D plasmonic nanogap arrays for ultra-sensitive surface plasmon resonance detection,” Biosens. Bioelectron. 51(15), 401–407 (2014).
[Crossref] [PubMed]

O. M. Jakšić, Z. S. Jakšić, Ž. D. Čupić, D. V. Randjelović, and L. Z. Kolar-Anić, “Fluctuations in transient response of adsorption-based plasmonic sensors,” Sensor. Actuat. Biol. Chem. 190, 419–428 (2014).

U. Bhanu, M. R. Islam, L. Tetard, and S. I. Khondaker, “Photoluminescence quenching in gold - MoS2 hybrid nanoflakes,” Sci. Rep. 4, 5575 (2014).
[Crossref] [PubMed]

S.-P. Ng, X. Q. Lu, N. Ding, C.-M. L. Wu, and C.-S. Lee, “Plasmonic enhanced dye-sensitized solar cells with self-assembly gold-TiO2@core–shell nanoislands,” Sol. Energy 99, 115–125 (2014).
[Crossref]

Y. Oh, T. Son, S. Y. Kim, W. Lee, H. Yang, J. Choi, J.-S. Shin, and D. Kim, “Surface plasmon-enhanced nanoscopy of intracellular cytoskeletal actin filaments using random nanodot arrays,” Opt. Express 22(22), 27695–27706 (2014).
[Crossref]

M. R. Foreman, W.-L. Jin, and F. Vollmer, “Optimizing detection limits in whispering gallery mode biosensing,” Opt. Express 22(5), 5491–5511 (2014).
[Crossref] [PubMed]

2013 (3)

K. Jia, J.-L. Bijeon, P.-M. Adam, and R. E. Ionescu, “Large scale fabrication of gold nano-structured substrates via high temperature annealing and their direct use for the LSPR detection of atrazine,” Plasmonics 8(1), 143–151 (2013).
[Crossref]

H. Yu, K. Kim, K. Ma, W. Lee, J.-W. Choi, C.-O. Yun, and D. Kim, “Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance,” Biosens. Bioelectron. 41, 249–255 (2013).
[Crossref] [PubMed]

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

2012 (7)

C. Awada, G. Barbillon, F. Charra, L. Douillard, and J.-J. Greffet, “Experimental study of hot spots in gold/glass nanocomposite films by photoemission electron microscopy,” Phys. Rev. B 85(4), 045438 (2012).
[Crossref]

R. Santbergen, T. L. Temple, R. Liang, A. H. M. Smets, R. A. C. M. M. van Swaaij, and M. Zeman, “Application of plasmonic silver island films in thin-film silicon solar cells,” J. Opt. 14(2), 024010 (2012).
[Crossref]

A. Urich, A. Pospischil, M. M. Furchi, D. Dietze, K. Unterrainer, and T. Mueller, “Silver nanoisland enhanced Raman interaction in graphene,” Appl. Phys. Lett. 101(15), 153113 (2012).
[Crossref]

Y. Liu and H. W. M. Salemink, “Photonic crystal-based all-optical on-chip sensor,” Opt. Express 20(18), 19912–19920 (2012).
[Crossref] [PubMed]

S. Moon, Y. Kim, Y. Oh, H. Lee, H. C. Kim, K. Lee, and D. Kim, “Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization,” Biosens. Bioelectron. 32(1), 141–147 (2012).
[Crossref] [PubMed]

W. Lee and D. Kim, “Field-matter integral overlap to estimate the sensitivity of surface plasmon resonance biosensors,” J. Opt. Soc. Am. A 29(7), 1367–1376 (2012).
[Crossref] [PubMed]

K. Hotta, A. Yamaguchi, and N. Teramae, “Nanoporous waveguide sensor with optimized nanoarchitectures for highly sensitive label-free biosensing,” ACS Nano 6(2), 1541–1547 (2012).
[Crossref] [PubMed]

2011 (5)

N.-H. Kim, W. K. Jung, and K. M. Byun, “Correlation analysis between plasmon field distribution and sensitivity enhancement in reflection- and transmission-type localized surface plasmon resonance biosensors,” Appl. Opt. 50(25), 4982–4988 (2011).
[Crossref]

S. Chen, M. Svedendahl, R. P. Duyne, and M. Käll, “Plasmon-enhanced colorimetric ELISA with single molecule sensitivity,” Nano Lett. 11(4), 1826–1830 (2011).
[Crossref] [PubMed]

S. M. Tabakman, L. Lau, J. T. Robinson, J. Price, S. P. Sherlock, H. Wang, B. Zhang, Z. Chen, S. Tangsombatvisit, J. A. Jarrell, P. J. Utz, and H. Dai, “Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range,” Nat. Commun. 2, 466 (2011).
[Crossref] [PubMed]

M. A. Santiago-Cordoba, S. V. Boriskina, F. Vollmer, and M. C. Demirel, “Nanoparticle-based protein detection by optical shift of a resonant microcavity,” Appl. Phys. Lett. 99(7), 073701 (2011).
[Crossref]

Y. Oh, W. Lee, and D. Kim, “Colocalization of gold nanoparticle-conjugated DNA hybridization for enhanced surface plasmon detection using nanograting antennas,” Opt. Lett. 36(8), 1353–1355 (2011).
[Crossref] [PubMed]

2010 (5)

S. Moon, D. J. Kim, K. Kim, D. Kim, H. Lee, K. Lee, and S. Haam, “Surface-enhanced plasmon resonance detection of nanoparticle-conjugated DNA hybridization,” Appl. Opt. 49(3), 484–491 (2010).
[Crossref] [PubMed]

K. Ma, D. J. Kim, K. Kim, S. Moon, and D. Kim, “Target-localized nanograting-based surface plasmon resonance detection toward label-free molecular biosensing,” IEEE J. Sel. Top. Quantum Electron. 16(4), 1004–1014 (2010).
[Crossref]

K. Kim, J.-W. Choi, K. Ma, R. Lee, K.-H. Yoo, C.-O. Yun, and D. Kim, “Nanoisland-based random activation of fluorescence for visualizing endocytotic internalization of adenovirus,” Small 6(12), 1293–1299 (2010).
[Crossref] [PubMed]

T.-H. Lee, S.-W. Lee, J.-A. Jung, J. Ahn, M.-G. Kim, and Y.-B. Shin, “Signal amplification by enzymatic reaction in an immunosensor based on localized surface plasmon resonance (LSPR),” Sensors (Basel) 10(3), 2045–2053 (2010).
[Crossref] [PubMed]

A. Shalabney and I. Abdulhalim, “Electromagnetic fields distribution in multilayer thin film structures and the origin of sensitivity enhancement in surface plasmon resonance sensors,” Sens. Actuators A Phys. 159(1), 24–32 (2010).
[Crossref]

2009 (8)

S. Das, H. Vikalo, and A. Hassibi, “On scaling laws of biosensors; a stochastic approach,” J. Appl. Phys. 105(10), 102021 (2009).
[Crossref]

A. N. Pisarenko, W. U. Spendel, R. T. Taylor, J. D. Brown, J. A. Cox, and G. E. Pacey, “Detection of ozone gas using gold nanoislands and surface plasmon resonance,” Talanta 80(2), 777–780 (2009).
[Crossref] [PubMed]

K. M. Byun, S. M. Jang, S. J. Kim, and D. Kim, “Effect of target localization on the sensitivity of a localized surface plasmon resonance biosensor based on subwavelength metallic nanostructures,” J. Opt. Soc. Am. A 26(4), 1027–1034 (2009).
[Crossref] [PubMed]

X. D. Hoa, A. G. Kirk, and M. Tabrizian, “Enhanced SPR response from patterned immobilization of surface bioreceptors on nano-gratings,” Biosens. Bioelectron. 24(10), 3043–3048 (2009).
[Crossref] [PubMed]

W. Yuan, H. P. Ho, R. K. Y. Lee, and S. K. Kong, “Surface-enhanced Raman scattering biosensor for DNA detection on nanoparticle island substrates,” Appl. Opt. 48(22), 4329–4337 (2009).
[Crossref] [PubMed]

E. Giorgetti, S. Cicchi, M. Muniz-Miranda, G. Margheri, T. Del Rosso, A. Giusti, A. Rindi, G. Ghini, S. Sottini, A. Marcelli, and P. Foggi, “Förster resonance energy transfer (FRET) with a donor-acceptor system adsorbed on silver or gold nanoisland films,” Phys. Chem. Chem. Phys. 11(42), 9798–9803 (2009).
[Crossref] [PubMed]

E. Le Moal, S. Lévêque-Fort, M.-C. Potier, and E. Fort, “Nanoroughened plasmonic films for enhanced biosensing detection,” Nanotechnology 20(22), 225502 (2009).
[Crossref] [PubMed]

Y. Wang, M. Becker, L. Wang, J. Liu, R. Scholz, J. Peng, U. Gösele, S. Christiansen, D. H. Kim, and M. Steinhart, “Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions,” Nano Lett. 9(6), 2384–2389 (2009).
[Crossref] [PubMed]

2008 (5)

P. Cheng, D. Li, Z. Yuan, P. Chen, and D. Yang, “Enhancement of ZnO light emission via coupling with localized surface plasmon of Ag island film,” Appl. Phys. Lett. 92(4), 041119 (2008).
[Crossref]

D.-M. Yeh, C.-F. Huang, C.-Y. Chen, Y.-C. Lu, and C. C. Yang, “Localized surface plasmon-induced emission enhancement of a green light-emitting diode,” Nanotechnology 19(34), 345201 (2008).
[Crossref] [PubMed]

F. Vollmer and S. Arnold, “Whispering-gallery-mode biosensing: label-free detection down to single molecules,” Nat. Methods 5(7), 591–596 (2008).
[Crossref] [PubMed]

I. D. Block, N. Ganesh, M. Lu, and B. T. Cunningham, “A sensitivity model for predicting photonic crystal biosensor performance,” IEEE Sens. J. 8(3), 274–280 (2008).
[Crossref]

S. Szunerits, V. G. Praig, M. Manesse, and R. Boukherroub, “Gold island films on indium tin oxide for localized surface plasmon sensing,” Nanotechnology 19(19), 195712 (2008).
[Crossref] [PubMed]

2007 (9)

Y.-B. Shin, J.-M. Lee, M.-R. Park, M.-G. Kim, B. H. Chung, H.-B. Pyo, and S. Maeng, “Analysis of recombinant protein expression using localized surface plasmon resonance (LSPR),” Biosens. Bioelectron. 22(9-10), 2301–2307 (2007).
[Crossref] [PubMed]

I. Ruach-Nir, T. A. Bendikov, I. Doron-Mor, Z. Barkay, A. Vaskevich, and I. Rubinstein, “Silica-stabilized gold island films for transmission localized surface plasmon sensing,” J. Am. Chem. Soc. 129(1), 84–92 (2007).
[Crossref] [PubMed]

K. M. Byun, S. J. Yoon, D. Kim, and S. J. Kim, “Sensitivity analysis of a nanowire-based surface plasmon resonance biosensor in the presence of surface roughness,” J. Opt. Soc. Am. A 24(2), 522–529 (2007).
[Crossref] [PubMed]

A. Hassibi, H. Vikalo, and A. Hajimiri, “On noise processes and limits of performance in biosensors,” J. Appl. Phys. 102(1), 014909 (2007).
[Crossref]

L. Pang, G. M. Hwang, B. Slutsky, and Y. Fainman, “Spectral sensitivity of two-dimensional nanohole array surface plasmon polariton resonance sensor,” Appl. Phys. Lett. 91(12), 123112 (2007).
[Crossref]

K. M. Byun, S. J. Yoon, D. Kim, and S. J. Kim, “Experimental study of sensitivity enhancement in surface plasmon resonance biosensors by use of periodic metallic nanowires,” Opt. Lett. 32(13), 1902–1904 (2007).
[Crossref] [PubMed]

L. Malic, B. Cui, T. Veres, and M. Tabrizian, “Enhanced surface plasmon resonance imaging detection of DNA hybridization on periodic gold nanoposts,” Opt. Lett. 32(21), 3092–3094 (2007).
[Crossref] [PubMed]

K. A. Willets and R. P. Van Duyne, “Localized surface plasmon resonance spectroscopy and sensing,” Annu. Rev. Phys. Chem. 58(1), 267–297 (2007).
[Crossref] [PubMed]

I. M. Soganci, S. Nizamoglu, E. Mutlugun, O. Akin, and H. V. Demir, “Localized plasmon-engineered spontaneous emission of CdSe/ZnS nanocrystals closely-packed in the proximity of Ag nanoisland films for controlling emission linewidth, peak, and intensity,” Opt. Express 15(22), 14289–14298 (2007).
[Crossref] [PubMed]

2006 (2)

2005 (1)

2003 (4)

S. Park, G. Lee, S. H. Song, C. H. Oh, and P. S. Kim, “Resonant coupling of surface plasmons to radiation modes by use of dielectric gratings,” Opt. Lett. 28(20), 1870–1872 (2003).
[Crossref] [PubMed]

E. A. Jares-Erijman and T. M. Jovin, “FRET imaging,” Nat. Biotechnol. 21(11), 1387–1395 (2003).
[Crossref] [PubMed]

C. D. Geddes, H. Cao, I. Gryczynski, Z. Gryczynski, J. Fang, and J. R. Lakowicz, “Metal-enhanced fluorescence (MEF) due to silver colloids on a planar surface: potential applications of indocyanine green to in vivo imaging,” J. Phys. Chem. A 107(18), 3443–3449 (2003).
[Crossref]

J. Malicka, I. Gryczynski, J. Fang, J. Kusba, and J. R. Lakowicz, “Increased resonance energy transfer between fluorophores bound to DNA in proximity to metallic silver particles,” Anal. Biochem. 315(2), 160–169 (2003).
[Crossref] [PubMed]

2001 (2)

Y. Kanamori, K. Hane, H. Sai, and H. Yugami, “100 nm period silicon antireflection structures fabricated using a porous alumina membrane mask,” Appl. Phys. Lett. 78(2), 142–143 (2001).
[Crossref]

W. A. Weimer and M. J. Dyer, “Tunable surface plasmon resonance silver films,” Appl. Phys. Lett. 79(19), 3164–3166 (2001).
[Crossref]

2000 (1)

L. He, M. D. Musick, S. R. Nicewarner, F. G. Salinas, S. J. Benkovic, M. J. Natan, and C. D. Keating, “Colloidal Au enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization,” J. Am. Chem. Soc. 122(38), 9071–9077 (2000).
[Crossref]

1999 (3)

S. Grésillon, L. Aigouy, A. C. Boccara, J. C. Rivoal, X. Quelin, C. Desmarest, P. Gadenne, V. A. Shubin, A. K. Sarychev, and V. M. Shalaev, “Experimental observation of localized optical excitations in random metal-dielectric films,” Phys. Rev. Lett. 82(22), 4520–4523 (1999).
[Crossref]

F. Meriaudeau, T. Downey, A. Wig, A. Passian, M. Buncick, and T. L. Ferrell, “Fiber optic sensor based on gold island plasmon resonance,” Sens. Actuators B Chem. 54(1–2), 106–117 (1999).
[Crossref]

B. P. Nelson, A. G. Frutos, J. M. Brockman, and R. M. Corn, “Near-infrared surface plasmon resonance measurements of ultrathin films. 1. Angle shift and SPR imaging experiments,” Anal. Chem. 71(18), 3928–3934 (1999).
[Crossref]

1982 (1)

Abdulhalim, I.

A. Shalabney and I. Abdulhalim, “Electromagnetic fields distribution in multilayer thin film structures and the origin of sensitivity enhancement in surface plasmon resonance sensors,” Sens. Actuators A Phys. 159(1), 24–32 (2010).
[Crossref]

Adam, P.-M.

K. Jia, J.-L. Bijeon, P.-M. Adam, and R. E. Ionescu, “Large scale fabrication of gold nano-structured substrates via high temperature annealing and their direct use for the LSPR detection of atrazine,” Plasmonics 8(1), 143–151 (2013).
[Crossref]

Ahn, J.

T.-H. Lee, S.-W. Lee, J.-A. Jung, J. Ahn, M.-G. Kim, and Y.-B. Shin, “Signal amplification by enzymatic reaction in an immunosensor based on localized surface plasmon resonance (LSPR),” Sensors (Basel) 10(3), 2045–2053 (2010).
[Crossref] [PubMed]

Aigouy, L.

S. Grésillon, L. Aigouy, A. C. Boccara, J. C. Rivoal, X. Quelin, C. Desmarest, P. Gadenne, V. A. Shubin, A. K. Sarychev, and V. M. Shalaev, “Experimental observation of localized optical excitations in random metal-dielectric films,” Phys. Rev. Lett. 82(22), 4520–4523 (1999).
[Crossref]

Akin, O.

Arnold, S.

F. Vollmer and S. Arnold, “Whispering-gallery-mode biosensing: label-free detection down to single molecules,” Nat. Methods 5(7), 591–596 (2008).
[Crossref] [PubMed]

Awada, C.

C. Awada, G. Barbillon, F. Charra, L. Douillard, and J.-J. Greffet, “Experimental study of hot spots in gold/glass nanocomposite films by photoemission electron microscopy,” Phys. Rev. B 85(4), 045438 (2012).
[Crossref]

Badenes, G.

Barbillon, G.

C. Awada, G. Barbillon, F. Charra, L. Douillard, and J.-J. Greffet, “Experimental study of hot spots in gold/glass nanocomposite films by photoemission electron microscopy,” Phys. Rev. B 85(4), 045438 (2012).
[Crossref]

Barkay, Z.

I. Ruach-Nir, T. A. Bendikov, I. Doron-Mor, Z. Barkay, A. Vaskevich, and I. Rubinstein, “Silica-stabilized gold island films for transmission localized surface plasmon sensing,” J. Am. Chem. Soc. 129(1), 84–92 (2007).
[Crossref] [PubMed]

Becker, M.

Y. Wang, M. Becker, L. Wang, J. Liu, R. Scholz, J. Peng, U. Gösele, S. Christiansen, D. H. Kim, and M. Steinhart, “Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions,” Nano Lett. 9(6), 2384–2389 (2009).
[Crossref] [PubMed]

Bendikov, T. A.

I. Ruach-Nir, T. A. Bendikov, I. Doron-Mor, Z. Barkay, A. Vaskevich, and I. Rubinstein, “Silica-stabilized gold island films for transmission localized surface plasmon sensing,” J. Am. Chem. Soc. 129(1), 84–92 (2007).
[Crossref] [PubMed]

Benkovic, S. J.

L. He, M. D. Musick, S. R. Nicewarner, F. G. Salinas, S. J. Benkovic, M. J. Natan, and C. D. Keating, “Colloidal Au enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization,” J. Am. Chem. Soc. 122(38), 9071–9077 (2000).
[Crossref]

Bhanu, U.

U. Bhanu, M. R. Islam, L. Tetard, and S. I. Khondaker, “Photoluminescence quenching in gold - MoS2 hybrid nanoflakes,” Sci. Rep. 4, 5575 (2014).
[Crossref] [PubMed]

Bijeon, J.-L.

K. Jia, J.-L. Bijeon, P.-M. Adam, and R. E. Ionescu, “Large scale fabrication of gold nano-structured substrates via high temperature annealing and their direct use for the LSPR detection of atrazine,” Plasmonics 8(1), 143–151 (2013).
[Crossref]

Block, I. D.

I. D. Block, N. Ganesh, M. Lu, and B. T. Cunningham, “A sensitivity model for predicting photonic crystal biosensor performance,” IEEE Sens. J. 8(3), 274–280 (2008).
[Crossref]

Boccara, A. C.

S. Grésillon, L. Aigouy, A. C. Boccara, J. C. Rivoal, X. Quelin, C. Desmarest, P. Gadenne, V. A. Shubin, A. K. Sarychev, and V. M. Shalaev, “Experimental observation of localized optical excitations in random metal-dielectric films,” Phys. Rev. Lett. 82(22), 4520–4523 (1999).
[Crossref]

Boriskina, S. V.

M. A. Santiago-Cordoba, S. V. Boriskina, F. Vollmer, and M. C. Demirel, “Nanoparticle-based protein detection by optical shift of a resonant microcavity,” Appl. Phys. Lett. 99(7), 073701 (2011).
[Crossref]

Boukherroub, R.

S. Szunerits, V. G. Praig, M. Manesse, and R. Boukherroub, “Gold island films on indium tin oxide for localized surface plasmon sensing,” Nanotechnology 19(19), 195712 (2008).
[Crossref] [PubMed]

Brockman, J. M.

B. P. Nelson, A. G. Frutos, J. M. Brockman, and R. M. Corn, “Near-infrared surface plasmon resonance measurements of ultrathin films. 1. Angle shift and SPR imaging experiments,” Anal. Chem. 71(18), 3928–3934 (1999).
[Crossref]

Brown, J. D.

A. N. Pisarenko, W. U. Spendel, R. T. Taylor, J. D. Brown, J. A. Cox, and G. E. Pacey, “Detection of ozone gas using gold nanoislands and surface plasmon resonance,” Talanta 80(2), 777–780 (2009).
[Crossref] [PubMed]

Buncick, M.

F. Meriaudeau, T. Downey, A. Wig, A. Passian, M. Buncick, and T. L. Ferrell, “Fiber optic sensor based on gold island plasmon resonance,” Sens. Actuators B Chem. 54(1–2), 106–117 (1999).
[Crossref]

Byun, K. M.

Cao, H.

C. D. Geddes, H. Cao, I. Gryczynski, Z. Gryczynski, J. Fang, and J. R. Lakowicz, “Metal-enhanced fluorescence (MEF) due to silver colloids on a planar surface: potential applications of indocyanine green to in vivo imaging,” J. Phys. Chem. A 107(18), 3443–3449 (2003).
[Crossref]

Cesario, J.

Charra, F.

C. Awada, G. Barbillon, F. Charra, L. Douillard, and J.-J. Greffet, “Experimental study of hot spots in gold/glass nanocomposite films by photoemission electron microscopy,” Phys. Rev. B 85(4), 045438 (2012).
[Crossref]

Chen, C.-Y.

D.-M. Yeh, C.-F. Huang, C.-Y. Chen, Y.-C. Lu, and C. C. Yang, “Localized surface plasmon-induced emission enhancement of a green light-emitting diode,” Nanotechnology 19(34), 345201 (2008).
[Crossref] [PubMed]

Chen, P.

P. Cheng, D. Li, Z. Yuan, P. Chen, and D. Yang, “Enhancement of ZnO light emission via coupling with localized surface plasmon of Ag island film,” Appl. Phys. Lett. 92(4), 041119 (2008).
[Crossref]

Chen, S.

S. Chen, M. Svedendahl, R. P. Duyne, and M. Käll, “Plasmon-enhanced colorimetric ELISA with single molecule sensitivity,” Nano Lett. 11(4), 1826–1830 (2011).
[Crossref] [PubMed]

Chen, Z.

S. M. Tabakman, L. Lau, J. T. Robinson, J. Price, S. P. Sherlock, H. Wang, B. Zhang, Z. Chen, S. Tangsombatvisit, J. A. Jarrell, P. J. Utz, and H. Dai, “Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range,” Nat. Commun. 2, 466 (2011).
[Crossref] [PubMed]

Cheng, P.

P. Cheng, D. Li, Z. Yuan, P. Chen, and D. Yang, “Enhancement of ZnO light emission via coupling with localized surface plasmon of Ag island film,” Appl. Phys. Lett. 92(4), 041119 (2008).
[Crossref]

Cho, W. J.

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

Choi, J.

Choi, J.-W.

H. Yu, K. Kim, K. Ma, W. Lee, J.-W. Choi, C.-O. Yun, and D. Kim, “Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance,” Biosens. Bioelectron. 41, 249–255 (2013).
[Crossref] [PubMed]

K. Kim, J.-W. Choi, K. Ma, R. Lee, K.-H. Yoo, C.-O. Yun, and D. Kim, “Nanoisland-based random activation of fluorescence for visualizing endocytotic internalization of adenovirus,” Small 6(12), 1293–1299 (2010).
[Crossref] [PubMed]

Christiansen, S.

Y. Wang, M. Becker, L. Wang, J. Liu, R. Scholz, J. Peng, U. Gösele, S. Christiansen, D. H. Kim, and M. Steinhart, “Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions,” Nano Lett. 9(6), 2384–2389 (2009).
[Crossref] [PubMed]

Chung, B. H.

Y.-B. Shin, J.-M. Lee, M.-R. Park, M.-G. Kim, B. H. Chung, H.-B. Pyo, and S. Maeng, “Analysis of recombinant protein expression using localized surface plasmon resonance (LSPR),” Biosens. Bioelectron. 22(9-10), 2301–2307 (2007).
[Crossref] [PubMed]

Chung, K.

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

Cicchi, S.

E. Giorgetti, S. Cicchi, M. Muniz-Miranda, G. Margheri, T. Del Rosso, A. Giusti, A. Rindi, G. Ghini, S. Sottini, A. Marcelli, and P. Foggi, “Förster resonance energy transfer (FRET) with a donor-acceptor system adsorbed on silver or gold nanoisland films,” Phys. Chem. Chem. Phys. 11(42), 9798–9803 (2009).
[Crossref] [PubMed]

Corn, R. M.

B. P. Nelson, A. G. Frutos, J. M. Brockman, and R. M. Corn, “Near-infrared surface plasmon resonance measurements of ultrathin films. 1. Angle shift and SPR imaging experiments,” Anal. Chem. 71(18), 3928–3934 (1999).
[Crossref]

Cox, J. A.

A. N. Pisarenko, W. U. Spendel, R. T. Taylor, J. D. Brown, J. A. Cox, and G. E. Pacey, “Detection of ozone gas using gold nanoislands and surface plasmon resonance,” Talanta 80(2), 777–780 (2009).
[Crossref] [PubMed]

Cui, B.

Cunningham, B. T.

I. D. Block, N. Ganesh, M. Lu, and B. T. Cunningham, “A sensitivity model for predicting photonic crystal biosensor performance,” IEEE Sens. J. 8(3), 274–280 (2008).
[Crossref]

Cupic, Ž. D.

O. M. Jakšić, Z. S. Jakšić, Ž. D. Čupić, D. V. Randjelović, and L. Z. Kolar-Anić, “Fluctuations in transient response of adsorption-based plasmonic sensors,” Sensor. Actuat. Biol. Chem. 190, 419–428 (2014).

Dai, H.

S. M. Tabakman, L. Lau, J. T. Robinson, J. Price, S. P. Sherlock, H. Wang, B. Zhang, Z. Chen, S. Tangsombatvisit, J. A. Jarrell, P. J. Utz, and H. Dai, “Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range,” Nat. Commun. 2, 466 (2011).
[Crossref] [PubMed]

Das, S.

S. Das, H. Vikalo, and A. Hassibi, “On scaling laws of biosensors; a stochastic approach,” J. Appl. Phys. 105(10), 102021 (2009).
[Crossref]

Del Rosso, T.

E. Giorgetti, S. Cicchi, M. Muniz-Miranda, G. Margheri, T. Del Rosso, A. Giusti, A. Rindi, G. Ghini, S. Sottini, A. Marcelli, and P. Foggi, “Förster resonance energy transfer (FRET) with a donor-acceptor system adsorbed on silver or gold nanoisland films,” Phys. Chem. Chem. Phys. 11(42), 9798–9803 (2009).
[Crossref] [PubMed]

Demir, H. V.

Demirel, M. C.

M. A. Santiago-Cordoba, S. V. Boriskina, F. Vollmer, and M. C. Demirel, “Nanoparticle-based protein detection by optical shift of a resonant microcavity,” Appl. Phys. Lett. 99(7), 073701 (2011).
[Crossref]

Desmarest, C.

S. Grésillon, L. Aigouy, A. C. Boccara, J. C. Rivoal, X. Quelin, C. Desmarest, P. Gadenne, V. A. Shubin, A. K. Sarychev, and V. M. Shalaev, “Experimental observation of localized optical excitations in random metal-dielectric films,” Phys. Rev. Lett. 82(22), 4520–4523 (1999).
[Crossref]

Dietze, D.

A. Urich, A. Pospischil, M. M. Furchi, D. Dietze, K. Unterrainer, and T. Mueller, “Silver nanoisland enhanced Raman interaction in graphene,” Appl. Phys. Lett. 101(15), 153113 (2012).
[Crossref]

Ding, N.

S.-P. Ng, X. Q. Lu, N. Ding, C.-M. L. Wu, and C.-S. Lee, “Plasmonic enhanced dye-sensitized solar cells with self-assembly gold-TiO2@core–shell nanoislands,” Sol. Energy 99, 115–125 (2014).
[Crossref]

Doron-Mor, I.

I. Ruach-Nir, T. A. Bendikov, I. Doron-Mor, Z. Barkay, A. Vaskevich, and I. Rubinstein, “Silica-stabilized gold island films for transmission localized surface plasmon sensing,” J. Am. Chem. Soc. 129(1), 84–92 (2007).
[Crossref] [PubMed]

Douillard, L.

C. Awada, G. Barbillon, F. Charra, L. Douillard, and J.-J. Greffet, “Experimental study of hot spots in gold/glass nanocomposite films by photoemission electron microscopy,” Phys. Rev. B 85(4), 045438 (2012).
[Crossref]

Downey, T.

F. Meriaudeau, T. Downey, A. Wig, A. Passian, M. Buncick, and T. L. Ferrell, “Fiber optic sensor based on gold island plasmon resonance,” Sens. Actuators B Chem. 54(1–2), 106–117 (1999).
[Crossref]

Duyne, R. P.

S. Chen, M. Svedendahl, R. P. Duyne, and M. Käll, “Plasmon-enhanced colorimetric ELISA with single molecule sensitivity,” Nano Lett. 11(4), 1826–1830 (2011).
[Crossref] [PubMed]

Dyer, M. J.

W. A. Weimer and M. J. Dyer, “Tunable surface plasmon resonance silver films,” Appl. Phys. Lett. 79(19), 3164–3166 (2001).
[Crossref]

Enoch, S.

Fainman, Y.

L. Pang, G. M. Hwang, B. Slutsky, and Y. Fainman, “Spectral sensitivity of two-dimensional nanohole array surface plasmon polariton resonance sensor,” Appl. Phys. Lett. 91(12), 123112 (2007).
[Crossref]

Fang, J.

J. Malicka, I. Gryczynski, J. Fang, J. Kusba, and J. R. Lakowicz, “Increased resonance energy transfer between fluorophores bound to DNA in proximity to metallic silver particles,” Anal. Biochem. 315(2), 160–169 (2003).
[Crossref] [PubMed]

C. D. Geddes, H. Cao, I. Gryczynski, Z. Gryczynski, J. Fang, and J. R. Lakowicz, “Metal-enhanced fluorescence (MEF) due to silver colloids on a planar surface: potential applications of indocyanine green to in vivo imaging,” J. Phys. Chem. A 107(18), 3443–3449 (2003).
[Crossref]

Ferrell, T. L.

F. Meriaudeau, T. Downey, A. Wig, A. Passian, M. Buncick, and T. L. Ferrell, “Fiber optic sensor based on gold island plasmon resonance,” Sens. Actuators B Chem. 54(1–2), 106–117 (1999).
[Crossref]

Foggi, P.

E. Giorgetti, S. Cicchi, M. Muniz-Miranda, G. Margheri, T. Del Rosso, A. Giusti, A. Rindi, G. Ghini, S. Sottini, A. Marcelli, and P. Foggi, “Förster resonance energy transfer (FRET) with a donor-acceptor system adsorbed on silver or gold nanoisland films,” Phys. Chem. Chem. Phys. 11(42), 9798–9803 (2009).
[Crossref] [PubMed]

Foreman, M. R.

Fort, E.

E. Le Moal, S. Lévêque-Fort, M.-C. Potier, and E. Fort, “Nanoroughened plasmonic films for enhanced biosensing detection,” Nanotechnology 20(22), 225502 (2009).
[Crossref] [PubMed]

Frutos, A. G.

B. P. Nelson, A. G. Frutos, J. M. Brockman, and R. M. Corn, “Near-infrared surface plasmon resonance measurements of ultrathin films. 1. Angle shift and SPR imaging experiments,” Anal. Chem. 71(18), 3928–3934 (1999).
[Crossref]

Furchi, M. M.

A. Urich, A. Pospischil, M. M. Furchi, D. Dietze, K. Unterrainer, and T. Mueller, “Silver nanoisland enhanced Raman interaction in graphene,” Appl. Phys. Lett. 101(15), 153113 (2012).
[Crossref]

Gadenne, P.

S. Grésillon, L. Aigouy, A. C. Boccara, J. C. Rivoal, X. Quelin, C. Desmarest, P. Gadenne, V. A. Shubin, A. K. Sarychev, and V. M. Shalaev, “Experimental observation of localized optical excitations in random metal-dielectric films,” Phys. Rev. Lett. 82(22), 4520–4523 (1999).
[Crossref]

Ganesh, N.

I. D. Block, N. Ganesh, M. Lu, and B. T. Cunningham, “A sensitivity model for predicting photonic crystal biosensor performance,” IEEE Sens. J. 8(3), 274–280 (2008).
[Crossref]

Garoff, S.

Geddes, C. D.

C. D. Geddes, H. Cao, I. Gryczynski, Z. Gryczynski, J. Fang, and J. R. Lakowicz, “Metal-enhanced fluorescence (MEF) due to silver colloids on a planar surface: potential applications of indocyanine green to in vivo imaging,” J. Phys. Chem. A 107(18), 3443–3449 (2003).
[Crossref]

Ghini, G.

E. Giorgetti, S. Cicchi, M. Muniz-Miranda, G. Margheri, T. Del Rosso, A. Giusti, A. Rindi, G. Ghini, S. Sottini, A. Marcelli, and P. Foggi, “Förster resonance energy transfer (FRET) with a donor-acceptor system adsorbed on silver or gold nanoisland films,” Phys. Chem. Chem. Phys. 11(42), 9798–9803 (2009).
[Crossref] [PubMed]

Giorgetti, E.

E. Giorgetti, S. Cicchi, M. Muniz-Miranda, G. Margheri, T. Del Rosso, A. Giusti, A. Rindi, G. Ghini, S. Sottini, A. Marcelli, and P. Foggi, “Förster resonance energy transfer (FRET) with a donor-acceptor system adsorbed on silver or gold nanoisland films,” Phys. Chem. Chem. Phys. 11(42), 9798–9803 (2009).
[Crossref] [PubMed]

Giusti, A.

E. Giorgetti, S. Cicchi, M. Muniz-Miranda, G. Margheri, T. Del Rosso, A. Giusti, A. Rindi, G. Ghini, S. Sottini, A. Marcelli, and P. Foggi, “Förster resonance energy transfer (FRET) with a donor-acceptor system adsorbed on silver or gold nanoisland films,” Phys. Chem. Chem. Phys. 11(42), 9798–9803 (2009).
[Crossref] [PubMed]

Gösele, U.

Y. Wang, M. Becker, L. Wang, J. Liu, R. Scholz, J. Peng, U. Gösele, S. Christiansen, D. H. Kim, and M. Steinhart, “Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions,” Nano Lett. 9(6), 2384–2389 (2009).
[Crossref] [PubMed]

Gramila, T. J.

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K. Jia, J.-L. Bijeon, P.-M. Adam, and R. E. Ionescu, “Large scale fabrication of gold nano-structured substrates via high temperature annealing and their direct use for the LSPR detection of atrazine,” Plasmonics 8(1), 143–151 (2013).
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L. He, M. D. Musick, S. R. Nicewarner, F. G. Salinas, S. J. Benkovic, M. J. Natan, and C. D. Keating, “Colloidal Au enhanced surface plasmon resonance for ultrasensitive detection of DNA hybridization,” J. Am. Chem. Soc. 122(38), 9071–9077 (2000).
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U. Bhanu, M. R. Islam, L. Tetard, and S. I. Khondaker, “Photoluminescence quenching in gold - MoS2 hybrid nanoflakes,” Sci. Rep. 4, 5575 (2014).
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Y. Oh, W. Lee, Y. Kim, and D. Kim, “Self-aligned colocalization of 3D plasmonic nanogap arrays for ultra-sensitive surface plasmon resonance detection,” Biosens. Bioelectron. 51(15), 401–407 (2014).
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Y. Oh, T. Son, S. Y. Kim, W. Lee, H. Yang, J. Choi, J.-S. Shin, and D. Kim, “Surface plasmon-enhanced nanoscopy of intracellular cytoskeletal actin filaments using random nanodot arrays,” Opt. Express 22(22), 27695–27706 (2014).
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Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
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H. Yu, K. Kim, K. Ma, W. Lee, J.-W. Choi, C.-O. Yun, and D. Kim, “Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance,” Biosens. Bioelectron. 41, 249–255 (2013).
[Crossref] [PubMed]

S. Moon, Y. Kim, Y. Oh, H. Lee, H. C. Kim, K. Lee, and D. Kim, “Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization,” Biosens. Bioelectron. 32(1), 141–147 (2012).
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W. Lee and D. Kim, “Field-matter integral overlap to estimate the sensitivity of surface plasmon resonance biosensors,” J. Opt. Soc. Am. A 29(7), 1367–1376 (2012).
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Y. Oh, W. Lee, and D. Kim, “Colocalization of gold nanoparticle-conjugated DNA hybridization for enhanced surface plasmon detection using nanograting antennas,” Opt. Lett. 36(8), 1353–1355 (2011).
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S. Moon, D. J. Kim, K. Kim, D. Kim, H. Lee, K. Lee, and S. Haam, “Surface-enhanced plasmon resonance detection of nanoparticle-conjugated DNA hybridization,” Appl. Opt. 49(3), 484–491 (2010).
[Crossref] [PubMed]

K. Ma, D. J. Kim, K. Kim, S. Moon, and D. Kim, “Target-localized nanograting-based surface plasmon resonance detection toward label-free molecular biosensing,” IEEE J. Sel. Top. Quantum Electron. 16(4), 1004–1014 (2010).
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K. Kim, J.-W. Choi, K. Ma, R. Lee, K.-H. Yoo, C.-O. Yun, and D. Kim, “Nanoisland-based random activation of fluorescence for visualizing endocytotic internalization of adenovirus,” Small 6(12), 1293–1299 (2010).
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K. M. Byun, S. M. Jang, S. J. Kim, and D. Kim, “Effect of target localization on the sensitivity of a localized surface plasmon resonance biosensor based on subwavelength metallic nanostructures,” J. Opt. Soc. Am. A 26(4), 1027–1034 (2009).
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K. M. Byun, S. J. Yoon, D. Kim, and S. J. Kim, “Sensitivity analysis of a nanowire-based surface plasmon resonance biosensor in the presence of surface roughness,” J. Opt. Soc. Am. A 24(2), 522–529 (2007).
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K. M. Byun, S. J. Yoon, D. Kim, and S. J. Kim, “Experimental study of sensitivity enhancement in surface plasmon resonance biosensors by use of periodic metallic nanowires,” Opt. Lett. 32(13), 1902–1904 (2007).
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K. Kim, S. J. Yoon, and D. Kim, “Nanowire-based enhancement of localized surface plasmon resonance for highly sensitive detection: a theoretical study,” Opt. Express 14(25), 12419–12431 (2006).
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D. Kim, “Effect of resonant localized plasmon coupling on the sensitivity enhancement of nanowire-based surface plasmon resonance biosensors,” J. Opt. Soc. Am. A 23(9), 2307–2314 (2006).
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Kim, D. H.

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

Y. Wang, M. Becker, L. Wang, J. Liu, R. Scholz, J. Peng, U. Gösele, S. Christiansen, D. H. Kim, and M. Steinhart, “Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions,” Nano Lett. 9(6), 2384–2389 (2009).
[Crossref] [PubMed]

Kim, D. J.

S. Moon, D. J. Kim, K. Kim, D. Kim, H. Lee, K. Lee, and S. Haam, “Surface-enhanced plasmon resonance detection of nanoparticle-conjugated DNA hybridization,” Appl. Opt. 49(3), 484–491 (2010).
[Crossref] [PubMed]

K. Ma, D. J. Kim, K. Kim, S. Moon, and D. Kim, “Target-localized nanograting-based surface plasmon resonance detection toward label-free molecular biosensing,” IEEE J. Sel. Top. Quantum Electron. 16(4), 1004–1014 (2010).
[Crossref]

Kim, H. C.

S. Moon, Y. Kim, Y. Oh, H. Lee, H. C. Kim, K. Lee, and D. Kim, “Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization,” Biosens. Bioelectron. 32(1), 141–147 (2012).
[Crossref] [PubMed]

Kim, J.

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

Kim, J. K.

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

Kim, K.

H. Yu, K. Kim, K. Ma, W. Lee, J.-W. Choi, C.-O. Yun, and D. Kim, “Enhanced detection of virus particles by nanoisland-based localized surface plasmon resonance,” Biosens. Bioelectron. 41, 249–255 (2013).
[Crossref] [PubMed]

K. Ma, D. J. Kim, K. Kim, S. Moon, and D. Kim, “Target-localized nanograting-based surface plasmon resonance detection toward label-free molecular biosensing,” IEEE J. Sel. Top. Quantum Electron. 16(4), 1004–1014 (2010).
[Crossref]

K. Kim, J.-W. Choi, K. Ma, R. Lee, K.-H. Yoo, C.-O. Yun, and D. Kim, “Nanoisland-based random activation of fluorescence for visualizing endocytotic internalization of adenovirus,” Small 6(12), 1293–1299 (2010).
[Crossref] [PubMed]

S. Moon, D. J. Kim, K. Kim, D. Kim, H. Lee, K. Lee, and S. Haam, “Surface-enhanced plasmon resonance detection of nanoparticle-conjugated DNA hybridization,” Appl. Opt. 49(3), 484–491 (2010).
[Crossref] [PubMed]

K. Kim, S. J. Yoon, and D. Kim, “Nanowire-based enhancement of localized surface plasmon resonance for highly sensitive detection: a theoretical study,” Opt. Express 14(25), 12419–12431 (2006).
[Crossref] [PubMed]

Kim, M.-G.

T.-H. Lee, S.-W. Lee, J.-A. Jung, J. Ahn, M.-G. Kim, and Y.-B. Shin, “Signal amplification by enzymatic reaction in an immunosensor based on localized surface plasmon resonance (LSPR),” Sensors (Basel) 10(3), 2045–2053 (2010).
[Crossref] [PubMed]

Y.-B. Shin, J.-M. Lee, M.-R. Park, M.-G. Kim, B. H. Chung, H.-B. Pyo, and S. Maeng, “Analysis of recombinant protein expression using localized surface plasmon resonance (LSPR),” Biosens. Bioelectron. 22(9-10), 2301–2307 (2007).
[Crossref] [PubMed]

Kim, N.-H.

Kim, P. S.

Kim, S. J.

Kim, S. Y.

Kim, Y.

Y. Oh, W. Lee, Y. Kim, and D. Kim, “Self-aligned colocalization of 3D plasmonic nanogap arrays for ultra-sensitive surface plasmon resonance detection,” Biosens. Bioelectron. 51(15), 401–407 (2014).
[Crossref] [PubMed]

S. Moon, Y. Kim, Y. Oh, H. Lee, H. C. Kim, K. Lee, and D. Kim, “Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization,” Biosens. Bioelectron. 32(1), 141–147 (2012).
[Crossref] [PubMed]

Kirk, A. G.

X. D. Hoa, A. G. Kirk, and M. Tabrizian, “Enhanced SPR response from patterned immobilization of surface bioreceptors on nano-gratings,” Biosens. Bioelectron. 24(10), 3043–3048 (2009).
[Crossref] [PubMed]

Kochuveedu, S. T.

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

Kolar-Anic, L. Z.

O. M. Jakšić, Z. S. Jakšić, Ž. D. Čupić, D. V. Randjelović, and L. Z. Kolar-Anić, “Fluctuations in transient response of adsorption-based plasmonic sensors,” Sensor. Actuat. Biol. Chem. 190, 419–428 (2014).

Kong, S. K.

Kusba, J.

J. Malicka, I. Gryczynski, J. Fang, J. Kusba, and J. R. Lakowicz, “Increased resonance energy transfer between fluorophores bound to DNA in proximity to metallic silver particles,” Anal. Biochem. 315(2), 160–169 (2003).
[Crossref] [PubMed]

Lakowicz, J. R.

J. Malicka, I. Gryczynski, J. Fang, J. Kusba, and J. R. Lakowicz, “Increased resonance energy transfer between fluorophores bound to DNA in proximity to metallic silver particles,” Anal. Biochem. 315(2), 160–169 (2003).
[Crossref] [PubMed]

C. D. Geddes, H. Cao, I. Gryczynski, Z. Gryczynski, J. Fang, and J. R. Lakowicz, “Metal-enhanced fluorescence (MEF) due to silver colloids on a planar surface: potential applications of indocyanine green to in vivo imaging,” J. Phys. Chem. A 107(18), 3443–3449 (2003).
[Crossref]

Lau, L.

S. M. Tabakman, L. Lau, J. T. Robinson, J. Price, S. P. Sherlock, H. Wang, B. Zhang, Z. Chen, S. Tangsombatvisit, J. A. Jarrell, P. J. Utz, and H. Dai, “Plasmonic substrates for multiplexed protein microarrays with femtomolar sensitivity and broad dynamic range,” Nat. Commun. 2, 466 (2011).
[Crossref] [PubMed]

Le Moal, E.

E. Le Moal, S. Lévêque-Fort, M.-C. Potier, and E. Fort, “Nanoroughened plasmonic films for enhanced biosensing detection,” Nanotechnology 20(22), 225502 (2009).
[Crossref] [PubMed]

Lee, C.-S.

S.-P. Ng, X. Q. Lu, N. Ding, C.-M. L. Wu, and C.-S. Lee, “Plasmonic enhanced dye-sensitized solar cells with self-assembly gold-TiO2@core–shell nanoislands,” Sol. Energy 99, 115–125 (2014).
[Crossref]

Lee, G.

Lee, H.

S. Moon, Y. Kim, Y. Oh, H. Lee, H. C. Kim, K. Lee, and D. Kim, “Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization,” Biosens. Bioelectron. 32(1), 141–147 (2012).
[Crossref] [PubMed]

S. Moon, D. J. Kim, K. Kim, D. Kim, H. Lee, K. Lee, and S. Haam, “Surface-enhanced plasmon resonance detection of nanoparticle-conjugated DNA hybridization,” Appl. Opt. 49(3), 484–491 (2010).
[Crossref] [PubMed]

Lee, J. E.

Y. H. Jang, K. Chung, L. N. Quan, B. Špačková, H. Šípová, S. Moon, W. J. Cho, H. Y. Shin, Y. J. Jang, J. E. Lee, S. T. Kochuveedu, M. J. Yoon, J. Kim, S. Yoon, J. K. Kim, D. Kim, J. Homola, and D. H. Kim, “Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors,” Nanoscale 5(24), 12261–12271 (2013).
[Crossref] [PubMed]

Lee, J.-M.

Y.-B. Shin, J.-M. Lee, M.-R. Park, M.-G. Kim, B. H. Chung, H.-B. Pyo, and S. Maeng, “Analysis of recombinant protein expression using localized surface plasmon resonance (LSPR),” Biosens. Bioelectron. 22(9-10), 2301–2307 (2007).
[Crossref] [PubMed]

Lee, K.

S. Moon, Y. Kim, Y. Oh, H. Lee, H. C. Kim, K. Lee, and D. Kim, “Grating-based surface plasmon resonance detection of core-shell nanoparticle mediated DNA hybridization,” Biosens. Bioelectron. 32(1), 141–147 (2012).
[Crossref] [PubMed]

S. Moon, D. J. Kim, K. Kim, D. Kim, H. Lee, K. Lee, and S. Haam, “Surface-enhanced plasmon resonance detection of nanoparticle-conjugated DNA hybridization,” Appl. Opt. 49(3), 484–491 (2010).
[Crossref] [PubMed]

Lee, R.

K. Kim, J.-W. Choi, K. Ma, R. Lee, K.-H. Yoo, C.-O. Yun, and D. Kim, “Nanoisland-based random activation of fluorescence for visualizing endocytotic internalization of adenovirus,” Small 6(12), 1293–1299 (2010).
[Crossref] [PubMed]

Lee, R. K. Y.

Lee, S.-W.

T.-H. Lee, S.-W. Lee, J.-A. Jung, J. Ahn, M.-G. Kim, and Y.-B. Shin, “Signal amplification by enzymatic reaction in an immunosensor based on localized surface plasmon resonance (LSPR),” Sensors (Basel) 10(3), 2045–2053 (2010).
[Crossref] [PubMed]

Lee, T.-H.

T.-H. Lee, S.-W. Lee, J.-A. Jung, J. Ahn, M.-G. Kim, and Y.-B. Shin, “Signal amplification by enzymatic reaction in an immunosensor based on localized surface plasmon resonance (LSPR),” Sensors (Basel) 10(3), 2045–2053 (2010).
[Crossref] [PubMed]

Lee, W.

Lévêque-Fort, S.

E. Le Moal, S. Lévêque-Fort, M.-C. Potier, and E. Fort, “Nanoroughened plasmonic films for enhanced biosensing detection,” Nanotechnology 20(22), 225502 (2009).
[Crossref] [PubMed]

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P. Cheng, D. Li, Z. Yuan, P. Chen, and D. Yang, “Enhancement of ZnO light emission via coupling with localized surface plasmon of Ag island film,” Appl. Phys. Lett. 92(4), 041119 (2008).
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R. Santbergen, T. L. Temple, R. Liang, A. H. M. Smets, R. A. C. M. M. van Swaaij, and M. Zeman, “Application of plasmonic silver island films in thin-film silicon solar cells,” J. Opt. 14(2), 024010 (2012).
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Liu, J.

Y. Wang, M. Becker, L. Wang, J. Liu, R. Scholz, J. Peng, U. Gösele, S. Christiansen, D. H. Kim, and M. Steinhart, “Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions,” Nano Lett. 9(6), 2384–2389 (2009).
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Lu, M.

I. D. Block, N. Ganesh, M. Lu, and B. T. Cunningham, “A sensitivity model for predicting photonic crystal biosensor performance,” IEEE Sens. J. 8(3), 274–280 (2008).
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Lu, X. Q.

S.-P. Ng, X. Q. Lu, N. Ding, C.-M. L. Wu, and C.-S. Lee, “Plasmonic enhanced dye-sensitized solar cells with self-assembly gold-TiO2@core–shell nanoislands,” Sol. Energy 99, 115–125 (2014).
[Crossref]

Lu, Y.-C.

D.-M. Yeh, C.-F. Huang, C.-Y. Chen, Y.-C. Lu, and C. C. Yang, “Localized surface plasmon-induced emission enhancement of a green light-emitting diode,” Nanotechnology 19(34), 345201 (2008).
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F. Vollmer and S. Arnold, “Whispering-gallery-mode biosensing: label-free detection down to single molecules,” Nat. Methods 5(7), 591–596 (2008).
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Wang, L.

Y. Wang, M. Becker, L. Wang, J. Liu, R. Scholz, J. Peng, U. Gösele, S. Christiansen, D. H. Kim, and M. Steinhart, “Nanostructured gold films for SERS by block copolymer-templated galvanic displacement reactions,” Nano Lett. 9(6), 2384–2389 (2009).
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Figures (5)

Fig. 1
Fig. 1 Schematics of numerical models: (a) non-specific detection using nanoislands for 3D RCWA calculation. Specific detection is considered in two distinct scenarios: (b) non-colocalized and (c) colocalized detection. The red spots represent localized fields. In the colocalized detection, an antibody layer is shown to exist only at the localized fields while it it covers nanoislands surface in non-colocalized detection.
Fig. 2
Fig. 2 (a) SEM image of a synthesized nanoisland sample used for the calculation. Also shown below the image is the conversion into the binarized nanoislands pattern to build a numerical model. (b) 2D near-field distribution (top) at an axial distance z = 25 nm from the surface, which is overlayed on the binarized boundary pattern (middle planes) and the SEM nanoisland sample image (bottom). The SEM image corresponds to the square inset of (a) in an area of 2 × 2 μm2.
Fig. 3
Fig. 3 (a) Calculated optical signature (OI) for non-specific detection of targets of varying size of target. The optical signature was normalized by the overlap without target molecules. Confidence interval of the detection appears as a color band. The inset shows a magnified image for the case of target diameter ϕ = 25 nm Normalized optical signature for targets of varying size on nanoislands: (b) non-colocalized specific detection and (c) colocalized specific detection. Much reduced confidence interval is clear, particularly in the case of colocalized detection, for which the optical signature almost appears as a line.
Fig. 4
Fig. 4 The relative confidence interval (RCI) calculated for target size of ϕ = 25 nm with respect to target concentration in non-specific, non-colocalized, and colocalized detection. The horizontal dashed line represents RCI = 1.
Fig. 5
Fig. 5 (a) The optical signature OI with target concentration for targets of ϕ = 25 nm under the colocalized detection at different wavelengths λ = 488, 633, and 760 nm. Insets present the near-field distributions at the respective wavelength. (b) RCI at different wavelengths λ = 488, 633, and 760 nm. The RCI at λ = 488 and 760 nm almost overlaps thus is maginified in the inset, where RCI at λ = 488 nm is slightly larger than that of λ = 760 nm. Thick solid lines in the inset are the grids.

Tables (1)

Tables Icon

Table 1 Relative confidence interval (RCI) at 95% confidence level. 2.03E11 was selected as the target concentration that produces normalized OI = 0.001 in non-specific detection.

Equations (25)

Equations on this page are rendered with MathJax. Learn more.

O I = ε ( r ) | E t ( r ) | 2 d r .
ε ( r ) = k N t ( ε t a r g e t - ε b u f f e r ) δ ( r - r k ) + ε b u f f e r .
O I = ( ε t a r g e t - ε b u f f e r ) Σ k N t | E t ( r k ) | 2 + ε b u f f e r E t ( r k ) | 2 d r .
D S = Δ O I / Δ N ( ε t a r g e t | - ε b u f f e r ) [ Σ j N t + N | E t ( r j ) | 2 Σ k N t | E t ( r k ) | 2 ] / N .
O I = Σ i = 0 3 E i 2 ε 0 ( S i - A t K i ) + E i 2 ε 1 A t K i Σ i = 0 3 ( E i 2 ε 0 S i + E i 2 ε 1 A t K i )
P [ K i = k ] = ( χ S i ) k k ! e χ S i .
O I ¯ = Σ i = 0 3 ( E i 2 ε 0 S i + E i 2 ε 1 A t K i ) / O I n o t a r g e t
m O I ¯ 2 = χ Σ i = 0 3 b i S i + Σ i = 0 3 a i and σ O I ¯ 2 = χ Σ i = 0 3 b i 2 S i
χ ^ = ( O I ¯ Σ i = 0 3 a i ) / Σ i = 0 3 b i S i
m χ ^ 2 = χ and σ χ ^ 2 = χ Σ i = 0 3 b i 2 S i [ Σ i = 0 3 b i S i ] 2
χ ^ - 1 . 9 6 0 σ χ χ χ ^ + 1 . 9 6 0 σ χ .
O I ^ - 1 . 9 6 0 σ O I ¯ O I ¯ O I ^ + 1 . 9 6 0 σ O I ¯ .
O I Σ i = 0 3 ( E i 2 ε 0 S i , i n s i d e + E i 2 ε 1 A t K i ) + Σ i = 0 3 E i 2 ε 0 S i , o u t s i d e .
p [ K i = k ] = ( χ S i , i n s i d e ) k k ! e χ S i , i n s i d e
O I ¯ = Σ i = 0 3 { E i 2 ε 0 S i , i n s i d e + E i 2 ε 1 A t K i } + Σ i = 0 3 E i 2 ε 0 S i , o u t s i d e O I n o t a r g e t
m O I ¯ 2 = χ Σ i = 0 3 b i S i , i n s i d e + Σ i = 0 3 a i + Σ i = 0 3 E i 2 ε 0 S i , i n s i d e / O I n o t a r g e t
σ O I ¯ 2 = χ Σ i = 0 3 b i 2 S i , i n s i d e
χ ^ = O I ¯ Σ i = 0 3 a i Σ i = 0 3 E i 2 ε 0 S i , o u t s i d e / O I n o t a r g e t Σ i = 0 3 b i S i , i n s i d e
O I Σ i = 2 3 ( E i 2 ε 0 S i , i n s i d e + E i 2 ε 1 A t K i ) + Σ i = 0 1 E i 2 ε 0 S i , i n s i d e + Σ i = 0 3 E i 2 ε 0 S i , o u t s i d e
O I ¯ = Σ i = 2 3 ( E i 2 ε 0 S i , i n s i d e + E i 2 ε 1 A t K i ) + Σ i = 0 1 E i 2 ε 0 S i , i n s i d e + Σ i = 0 3 E i 2 ε 0 S i , o u t s i d e O I n o t a r g e t .
m O I ¯ 2 = χ Σ i = 2 3 b i S i , i n s i d e + Σ i = 0 1 a i + ( Σ i = 0 1 E i 2 ε 0 S i , i n s i d e + Σ i = 0 3 E i 2 ε 0 S i , o u t s i d e ) / O I n o t a r g e t
σ O I ¯ 2 = χ Σ i = 2 3 b i 2 S i , i n s i d e
χ ^ = O I ¯ Σ i = 2 3 a i ( Σ i = 0 1 E i 2 ε 0 S i , i n s i d e + Σ i = 0 3 E i 2 ε 0 S i , o u t s i d e ) / O I n o t a r g e t Σ i = 2 3 b i S i , i n s i d e
O I ¯ t o t a l = O I ¯ + O ( N O I S E )
p ( ε , E t ) = 1 2 π σ ε 2 σ E t 2 exp [ 1 2 ( ε 2 σ ε 2 + E t 2 σ E t 2 ) ] .

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