Abstract

We present in-vivo 3D human vocal fold images with polarization sensitive optical coherence tomography (PS-OCT). Characterizing the extent and location of vocal fold lesions provides useful information in guiding surgeons during phonomicrosurgery. Previous studies showed that PS-OCT imaging can distinguish vocal fold lesions from normal tissue, but these studies were limited to 2D cross-sectional imaging and were susceptible to sampling error. In-vivo 3D endoscopic imaging was performed by using a recently developed 2-axis MEMS scanning catheter and a spectral domain OCT (SD-OCT), running at 18.5 frames/s. Imaging was performed in the operating room with patients under general anesthesia and 3D images were acquired either by 2D scanning of the scanner on the sites of interest or by combining 1D scanning and manual sliding to capture whole length of the vocal fold. Vocal fold scar, polyps, nodules, papilloma and malignant lesions were imaged and characteristics of individual lesions were analyzed in terms of spatial distribution and variation of tissue structure and birefringence. The 3D large sectional PS-OCT imaging showed that the spatial extent of vocal fold lesions can be found non-invasively with good contrast from normal tissue.

© 2010 OSA

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    [CrossRef]

2009 (4)

2008 (3)

2007 (4)

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

A. D. Aguirre, P. R. Hertz, Y. Chen, J. G. Fujimoto, W. Piyawattanametha, L. Fan, and M. C. Wu, “Two-axis MEMS scanning catheter for ultrahigh resolution three-dimensional and en face Imaging,” Opt. Express 15(5), 2445–2453 (2007), http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-5-2445 .
[CrossRef]

K. H. Kim, B. H. Park, G. N. Maguluri, T. W. Lee, F. J. Rogomentich, M. G. Bancu, B. E. Bouma, J. F. de Boer, and J. J. Bernstein, “Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography,” Opt. Express 15(26), 18130–18140 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-26-18130 .
[CrossRef]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

2006 (1)

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

2005 (3)

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005), http://www.opticsinfobase.org/abstract.cfm?URI=oe-13-11-3931 .
[CrossRef]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

2004 (2)

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 45(8), 2606–2612 (2004).
[CrossRef]

J. Strasswimmer, M. C. Pierce, B. H. Park, V. Neel, and J. F. de Boer, “Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma,” J. Biomed. Opt. 9(2), 292–298 (2004).
[CrossRef]

2002 (2)

2001 (1)

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[CrossRef]

1999 (1)

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Adler, D. C.

Aguirre, A. D.

Ahlers, C.

Anderson, R. R.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

Bancu, M. G.

Baumann, B.

Bernstein, J. J.

Bouma, B. E.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

K. H. Kim, B. H. Park, G. N. Maguluri, T. W. Lee, F. J. Rogomentich, M. G. Bancu, B. E. Bouma, J. F. de Boer, and J. J. Bernstein, “Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography,” Opt. Express 15(26), 18130–18140 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-26-18130 .
[CrossRef]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005), http://www.opticsinfobase.org/abstract.cfm?URI=oe-13-11-3931 .
[CrossRef]

B. E. Bouma and G. J. Tearney, “Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography,” Opt. Lett. 24(8), 531–533 (1999).
[CrossRef]

Bressner, J. E.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

Burns, J. A.

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

Cense, B.

Chan, R. C.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Chen, T. C.

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 45(8), 2606–2612 (2004).
[CrossRef]

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “In vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer by polarization-sensitive optical coherence tomography,” Opt. Lett. 27(18), 1610–1612 (2002), http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-27-18-1610 .
[CrossRef]

Chen, Y.

Chen, Z.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

de Boer, J. F.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

K. H. Kim, B. H. Park, G. N. Maguluri, T. W. Lee, F. J. Rogomentich, M. G. Bancu, B. E. Bouma, J. F. de Boer, and J. J. Bernstein, “Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography,” Opt. Express 15(26), 18130–18140 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-26-18130 .
[CrossRef]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005), http://www.opticsinfobase.org/abstract.cfm?URI=oe-13-11-3931 .
[CrossRef]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 45(8), 2606–2612 (2004).
[CrossRef]

J. Strasswimmer, M. C. Pierce, B. H. Park, V. Neel, and J. F. de Boer, “Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma,” J. Biomed. Opt. 9(2), 292–298 (2004).
[CrossRef]

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “In vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer by polarization-sensitive optical coherence tomography,” Opt. Lett. 27(18), 1610–1612 (2002), http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-27-18-1610 .
[CrossRef]

J. F. de Boer and T. E. Milner, “Review of polarization sensitive optical coherence tomography and Stokes vector determination,” J. Biomed. Opt. 7(3), 359–371 (2002).
[CrossRef]

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[CrossRef]

Desjardins, A. E.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Evans, J. A.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Fan, L.

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Fujimoto, J. G.

Geitzenauer, W.

Goto, H.

Götzinger, E.

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Halpern, E.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

Hee, M. R.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Hertz, P. R.

Hitzenberger, C. K.

Houser, S. L.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

Huang, D.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Huang, Q.

Iwaya, K.

Jang, I. K.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Jung, W.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

Kawabata, K.

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Kawana, K.

Kim, K. H.

Klein, A. M.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

Kobler, J. B.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

Lee, T. W.

Lin, C. P.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Maguluri, G. N.

Makita, S.

Mashimo, H.

Matsumoto, M.

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[CrossRef]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

McCormick, D. T.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

Michels, S.

Milner, T. E.

J. F. de Boer and T. E. Milner, “Review of polarization sensitive optical coherence tomography and Stokes vector determination,” J. Biomed. Opt. 7(3), 359–371 (2002).
[CrossRef]

Miura, M.

Miyazawa, A.

A. Miyazawa, M. Yamanari, S. Makita, M. Miura, K. Kawana, K. Iwaya, H. Goto, and Y. Yasuno, “Tissue discrimination in anterior eye using three optical parameters obtained by polarization sensitive optical coherence tomography,” Opt. Express 17(20), 17426–17440 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-20-17426 .
[CrossRef]

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[CrossRef]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Mujat, M.

Nadkarni, S. K.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

Nakagawa, N.

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[CrossRef]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Neel, V.

J. Strasswimmer, M. C. Pierce, B. H. Park, V. Neel, and J. F. de Boer, “Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma,” J. Biomed. Opt. 9(2), 292–298 (2004).
[CrossRef]

Nelson, J. S.

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[CrossRef]

Nishioka, N. S.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Oh, W. Y.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Oshika, T.

Park, B. H.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

K. H. Kim, B. H. Park, G. N. Maguluri, T. W. Lee, F. J. Rogomentich, M. G. Bancu, B. E. Bouma, J. F. de Boer, and J. J. Bernstein, “Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography,” Opt. Express 15(26), 18130–18140 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-26-18130 .
[CrossRef]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005), http://www.opticsinfobase.org/abstract.cfm?URI=oe-13-11-3931 .
[CrossRef]

J. Strasswimmer, M. C. Pierce, B. H. Park, V. Neel, and J. F. de Boer, “Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma,” J. Biomed. Opt. 9(2), 292–298 (2004).
[CrossRef]

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 45(8), 2606–2612 (2004).
[CrossRef]

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “In vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer by polarization-sensitive optical coherence tomography,” Opt. Lett. 27(18), 1610–1612 (2002), http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-27-18-1610 .
[CrossRef]

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[CrossRef]

Pierce, M. C.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005), http://www.opticsinfobase.org/abstract.cfm?URI=oe-13-11-3931 .
[CrossRef]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 45(8), 2606–2612 (2004).
[CrossRef]

J. Strasswimmer, M. C. Pierce, B. H. Park, V. Neel, and J. F. de Boer, “Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma,” J. Biomed. Opt. 9(2), 292–298 (2004).
[CrossRef]

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “In vivo depth-resolved birefringence measurements of the human retinal nerve fiber layer by polarization-sensitive optical coherence tomography,” Opt. Lett. 27(18), 1610–1612 (2002), http://www.opticsinfobase.org/ol/abstract.cfm?URI=ol-27-18-1610 .
[CrossRef]

Pircher, M.

Piyawattanametha, W.

Puliafito, C. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Rogomentich, F. J.

Sakai, S.

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[CrossRef]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Saxer, C.

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[CrossRef]

Schmidt-Erfurth, U.

Schmitt, J.

Schuman, J. S.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Shishkov, M.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

Srinivas, S. M.

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[CrossRef]

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Strasswimmer, J.

J. Strasswimmer, M. C. Pierce, B. H. Park, V. Neel, and J. F. de Boer, “Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma,” J. Biomed. Opt. 9(2), 292–298 (2004).
[CrossRef]

Sugawara, T.

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Suter, M. J.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Swanson, E. A.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Tearney, G. J.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005), http://www.opticsinfobase.org/abstract.cfm?URI=oe-13-11-3931 .
[CrossRef]

B. E. Bouma and G. J. Tearney, “Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography,” Opt. Lett. 24(8), 531–533 (1999).
[CrossRef]

Tien, N. C.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

Tsai, T. H.

Vakoc, B. J.

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Wang, L.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

Whittaker, P.

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

Wilder-Smith, P.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

Wu, M. C.

Yamanari, M.

Y. Yasuno, M. Yamanari, K. Kawana, T. Oshika, and M. Miura, “Investigation of post-glaucoma-surgery structures by three-dimensional and polarization sensitive anterior eye segment optical coherence tomography,” Opt. Express 17(5), 3980–3996 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-3980 .
[CrossRef]

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[CrossRef]

A. Miyazawa, M. Yamanari, S. Makita, M. Miura, K. Kawana, K. Iwaya, H. Goto, and Y. Yasuno, “Tissue discrimination in anterior eye using three optical parameters obtained by polarization sensitive optical coherence tomography,” Opt. Express 17(20), 17426–17440 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-20-17426 .
[CrossRef]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Yasuno, Y.

A. Miyazawa, M. Yamanari, S. Makita, M. Miura, K. Kawana, K. Iwaya, H. Goto, and Y. Yasuno, “Tissue discrimination in anterior eye using three optical parameters obtained by polarization sensitive optical coherence tomography,” Opt. Express 17(20), 17426–17440 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-20-17426 .
[CrossRef]

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[CrossRef]

Y. Yasuno, M. Yamanari, K. Kawana, T. Oshika, and M. Miura, “Investigation of post-glaucoma-surgery structures by three-dimensional and polarization sensitive anterior eye segment optical coherence tomography,” Opt. Express 17(5), 3980–3996 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-3980 .
[CrossRef]

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Yatagai, T.

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Yun, S. H.

Zeitels, S. M.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

Zhang, J.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

Zhou, C.

Ann. Otol. Rhinol. Laryngol. (2)

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, “Imaging the mucosa of the human vocal fold with optical coherence tomography,” Ann. Otol. Rhinol. Laryngol. 114(9), 671–676 (2005).

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, “Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience,” Ann. Otol. Rhinol. Laryngol. 115(4), 277–284 (2006).

IEEE J. Sel. Top. Quantum Electron. (1)

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, “Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror,” IEEE J. Sel. Top. Quantum Electron. 11(4), 806–810 (2005).
[CrossRef]

Invest. Ophthalmol. Vis. Sci. (1)

B. Cense, T. C. Chen, B. H. Park, M. C. Pierce, and J. F. de Boer, “Thickness and birefringence of healthy retinal nerve fiber layer tissue measured with polarization-sensitive optical coherence tomography,” Invest. Ophthalmol. Vis. Sci. 45(8), 2606–2612 (2004).
[CrossRef]

J. Am. Coll. Cardiol. (1)

S. K. Nadkarni, M. C. Pierce, B. H. Park, J. F. de Boer, P. Whittaker, B. E. Bouma, J. E. Bressner, E. Halpern, S. L. Houser, and G. J. Tearney, “Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography,” J. Am. Coll. Cardiol. 49(13), 1474–1481 (2007).
[CrossRef]

J. Biomed. Opt. (4)

J. Strasswimmer, M. C. Pierce, B. H. Park, V. Neel, and J. F. de Boer, “Polarization-sensitive optical coherence tomography of invasive basal cell carcinoma,” J. Biomed. Opt. 9(2), 292–298 (2004).
[CrossRef]

J. F. de Boer and T. E. Milner, “Review of polarization sensitive optical coherence tomography and Stokes vector determination,” J. Biomed. Opt. 7(3), 359–371 (2002).
[CrossRef]

S. Sakai, N. Nakagawa, M. Yamanari, A. Miyazawa, Y. Yasuno, and M. Matsumoto, “Relationship between dermal birefringence and the skin surface roughness of photoaged human skin,” J. Biomed. Opt. 14(4), 044032 (2009).
[CrossRef]

B. H. Park, C. Saxer, S. M. Srinivas, J. S. Nelson, and J. F. de Boer, “In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography,” J. Biomed. Opt. 6(4), 474–479 (2001).
[CrossRef]

J. Invest. Dermatol. (1)

S. Sakai, M. Yamanari, A. Miyazawa, M. Matsumoto, N. Nakagawa, T. Sugawara, K. Kawabata, T. Yatagai, and Y. Yasuno, “In vivo three-dimensional birefringence analysis shows collagen differences between young and old photo-aged human skin,” J. Invest. Dermatol. 128(7), 1641–1647 (2008).
[CrossRef]

Nat. Med. (1)

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, “Comprehensive volumetric optical microscopy in vivo,” Nat. Med. 12(12), 1429–1433 (2007).
[CrossRef]

Opt. Express (8)

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, “Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 microm,” Opt. Express 13(11), 3931–3944 (2005), http://www.opticsinfobase.org/abstract.cfm?URI=oe-13-11-3931 .
[CrossRef]

A. D. Aguirre, P. R. Hertz, Y. Chen, J. G. Fujimoto, W. Piyawattanametha, L. Fan, and M. C. Wu, “Two-axis MEMS scanning catheter for ultrahigh resolution three-dimensional and en face Imaging,” Opt. Express 15(5), 2445–2453 (2007), http://www.opticsinfobase.org/abstract.cfm?URI=oe-15-5-2445 .
[CrossRef]

K. H. Kim, B. H. Park, G. N. Maguluri, T. W. Lee, F. J. Rogomentich, M. G. Bancu, B. E. Bouma, J. F. de Boer, and J. J. Bernstein, “Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography,” Opt. Express 15(26), 18130–18140 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-26-18130 .
[CrossRef]

W. Y. Oh, S. H. Yun, B. J. Vakoc, M. Shishkov, A. E. Desjardins, B. H. Park, J. F. de Boer, G. J. Tearney, and B. E. Bouma, “High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing,” Opt. Express 16(2), 1096–1103 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-2-1096 .
[CrossRef]

E. Götzinger, M. Pircher, W. Geitzenauer, C. Ahlers, B. Baumann, S. Michels, U. Schmidt-Erfurth, and C. K. Hitzenberger, “Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography,” Opt. Express 16(21), 16410–16422 (2008), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-16-21-16410 .
[CrossRef]

D. C. Adler, C. Zhou, T. H. Tsai, J. Schmitt, Q. Huang, H. Mashimo, and J. G. Fujimoto, “Three-dimensional endomicroscopy of the human colon using optical coherence tomography,” Opt. Express 17(2), 784–796 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-2-784 .
[CrossRef]

Y. Yasuno, M. Yamanari, K. Kawana, T. Oshika, and M. Miura, “Investigation of post-glaucoma-surgery structures by three-dimensional and polarization sensitive anterior eye segment optical coherence tomography,” Opt. Express 17(5), 3980–3996 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-5-3980 .
[CrossRef]

A. Miyazawa, M. Yamanari, S. Makita, M. Miura, K. Kawana, K. Iwaya, H. Goto, and Y. Yasuno, “Tissue discrimination in anterior eye using three optical parameters obtained by polarization sensitive optical coherence tomography,” Opt. Express 17(20), 17426–17440 (2009), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-17-20-17426 .
[CrossRef]

Opt. Lett. (2)

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, “Optical coherence tomography,” Science 254(5035), 1178–1181 (1991).
[CrossRef]

Supplementary Material (5)

» Media 1: MOV (3114 KB)     
» Media 2: MOV (2282 KB)     
» Media 3: MOV (3576 KB)     
» Media 4: MOV (2867 KB)     
» Media 5: MOV (3060 KB)     

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