Abstract

We present human retinal blood flow investigation for diabetic patients using Doppler Fourier domain optical coherence tomography (FDOCT). The scanning pattern consisted of two concentric circles around the optic nerve head. The blood flow in one patient with diabetes and no retinpathy and another patient with treated proliferative diabetic retinopathy were measured. The patient without retinopathy showed a total blood flow value at the lower level of the normal range. The flow distribution between superior and inferior retina was balanced. The patient with diabetic retinopathy had a flow value lower than the normal people. Our study shows that Doppler FD-OCT can be used to evaluate the total retinal blood flow in patients with retinal diseases.

© 2009 Optical Society of America

PDF Article

References

  • View by:
  • |
  • |
  • |

  1. C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
    [CrossRef]
  2. A. Mendivil, V. Cuartero, and M. P. Mendivil, "Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study," Br. J. Ophthalmol. l 79, 413-416 (1995).
    [CrossRef]
  3. D. Guven, H. Ozdemir, and B. Hasanreisoglu, "Hemodynamic alterations in diabetic retinopathy," Ophthalmology 103, 1245-1249 (1996).
  4. J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
    [CrossRef]
  5. S. Fujioka, K. Karashima, N. Nishikawa, and Y. Saito, "Correlation between higher blood flow velocity in the central retinal vein than in the central retinal artery and severity of nonproliferative diabetic retinopathy," Jpn. J. Ophthalmol. 50, 312-317 (2006).
    [CrossRef]
  6. M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
    [CrossRef]
  7. D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
    [CrossRef]
  8. M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).
  9. C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).
  10. M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).
  11. J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).
  12. J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).
  13. X. J. Wang, T. E. Milner, and J. S. Nelson, "Characterization of fluid flow velocity by optical Doppler tomography," Opt. Lett. 20, 1337-1339 (1995).
    [CrossRef]
  14. J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, J. K. Barton, and A. J. Welch. "In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography," Opt. Lett. 22, 1439-1441 (1997).
    [CrossRef]
  15. Y. Zhao, Z. Chen, C. Saxer, Q. Shen, S. Xiang, J. F. de Boer, and J. S. Nelson. "Doppler standard deviation imaging for clinical monitoring of in vivo human skin blood flow," Opt. Lett. 25, 1358-1360 (2000).
    [CrossRef]
  16. S. Yazdanfar, A. M. Rollins, and J. A. Izatt, "In vivo imaging of human retinal flow dynamics by color Doppler optical coherence tomography," Arch. Ophthalmol. 121, 235-239 (2003).
  17. V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).
  18. S. Yazdanfar, A. M. Rollins, and J. A. Izatt. "Imaging and velocity of the human retinal circulation with color Doppler optical coherence tomography," Opt. Lett. 25, 1448-1450 (2000).
    [CrossRef]
  19. B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).
  20. R. A. Leitgeb, L. Schmetterer, C. K. Hitzenberger, A. F. Fercher, F. Berisha, M. Wojtkowski, and T. Bajraszewski, "Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography," Opt. Lett. 29, 171-173 (2004).
    [CrossRef]
  21. Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
    [CrossRef]
  22. S. Makita, T. Fabritius, and Y. Yasuno, "Quantitative retinal-blood flow measurement with three dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography," Opt. Lett. 33, 836-838 (2008).
    [CrossRef]
  23. R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
    [CrossRef]
  24. H. M. Wehbe, M. Ruggeri, S. Jiao, G. Gregori, C. A. Puliafito, and W. Zhao, "Calibration of blood flow measurement with spectral domain optical coherence tomography," in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2008), paper BMD75.
  25. H. Wehbe, M. Ruggeri, S. Jiao, G. Gregori, C. A. Puliafito, and W. Zhao, "Automatic retinal blood flow calculation using spectral domain optical coherence tomography," Opt. Express 15, 15193-15206 (2007).
    [CrossRef]
  26. Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
    [CrossRef]
  27. B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomed. Opt. 12, 041214 (2007).
    [CrossRef]
  28. Y. Wang, A. Lu, J. Gil-Flamer, O. Tan, D. Huang, "Measurement of total blood flow in the normal human retina using Doppler Fourier domain optical coherence tomography," Br. J. Ophthalmol. (in press).
  29. C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Vis. Sci. 26, 1124-1132 (1985).
  30. Q1. Jr. P. S. Garcia, P. T. Garcia, and R. B. Rosen, "Retinal blood flow in the normal human eye using the canon laser blood flowmeter," Ophthalmic Res. 34, 295-299 (2002).
    [CrossRef]
  31. C. W. C. Klaver, C. W. R. Wolfs, R. J. Vingerling, and T. V. P. de Jong, "Age-specific prevalence and causes of blindness and visual impairment in an older population," Arch. Ophthalmol. 116, 653-658 (2007).
  32. K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
    [CrossRef]
  33. J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
    [CrossRef]
  34. J. Flammer, "The vascular concept of glaucoma," Surv. Ophthalmol. 38, S3-S6 (1994).
  35. J. Kerr, P. Nelson, and C. O’Brien. "A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension," Am. J. Ophthalmol. 126, 42-51 (1998).
    [CrossRef]

2008 (4)

C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
[CrossRef]

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
[CrossRef]

S. Makita, T. Fabritius, and Y. Yasuno, "Quantitative retinal-blood flow measurement with three dimensional vessel geometry determination using ultrahigh-resolution Doppler optical coherence angiography," Opt. Lett. 33, 836-838 (2008).
[CrossRef]

2007 (5)

H. Wehbe, M. Ruggeri, S. Jiao, G. Gregori, C. A. Puliafito, and W. Zhao, "Automatic retinal blood flow calculation using spectral domain optical coherence tomography," Opt. Express 15, 15193-15206 (2007).
[CrossRef]

C. W. C. Klaver, C. W. R. Wolfs, R. J. Vingerling, and T. V. P. de Jong, "Age-specific prevalence and causes of blindness and visual impairment in an older population," Arch. Ophthalmol. 116, 653-658 (2007).

B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomed. Opt. 12, 041214 (2007).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
[CrossRef]

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

2006 (1)

S. Fujioka, K. Karashima, N. Nishikawa, and Y. Saito, "Correlation between higher blood flow velocity in the central retinal vein than in the central retinal artery and severity of nonproliferative diabetic retinopathy," Jpn. J. Ophthalmol. 50, 312-317 (2006).
[CrossRef]

2004 (1)

2003 (3)

S. Yazdanfar, A. M. Rollins, and J. A. Izatt, "In vivo imaging of human retinal flow dynamics by color Doppler optical coherence tomography," Arch. Ophthalmol. 121, 235-239 (2003).

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

2002 (2)

Q1. Jr. P. S. Garcia, P. T. Garcia, and R. B. Rosen, "Retinal blood flow in the normal human eye using the canon laser blood flowmeter," Ophthalmic Res. 34, 295-299 (2002).
[CrossRef]

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

2001 (1)

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

2000 (3)

1998 (1)

J. Kerr, P. Nelson, and C. O’Brien. "A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension," Am. J. Ophthalmol. 126, 42-51 (1998).
[CrossRef]

1997 (1)

1996 (2)

D. Guven, H. Ozdemir, and B. Hasanreisoglu, "Hemodynamic alterations in diabetic retinopathy," Ophthalmology 103, 1245-1249 (1996).

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

1995 (6)

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

A. Mendivil, V. Cuartero, and M. P. Mendivil, "Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study," Br. J. Ophthalmol. l 79, 413-416 (1995).
[CrossRef]

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

X. J. Wang, T. E. Milner, and J. S. Nelson, "Characterization of fluid flow velocity by optical Doppler tomography," Opt. Lett. 20, 1337-1339 (1995).
[CrossRef]

1994 (1)

J. Flammer, "The vascular concept of glaucoma," Surv. Ophthalmol. 38, S3-S6 (1994).

1991 (1)

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

1985 (1)

C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Vis. Sci. 26, 1124-1132 (1985).

Arya, A. V.

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

Bachmann, A. H.

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

Bajraszewski, T.

Barton, J. K.

Baumal, C. R.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

Berisha, F.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

R. A. Leitgeb, L. Schmetterer, C. K. Hitzenberger, A. F. Fercher, F. Berisha, M. Wojtkowski, and T. Bajraszewski, "Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography," Opt. Lett. 29, 171-173 (2004).
[CrossRef]

Blatter, C.

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

Bouma, B.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Bower, B. A.

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
[CrossRef]

B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomed. Opt. 12, 041214 (2007).
[CrossRef]

Broman, T. A.

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

Butt, Z.

J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
[CrossRef]

Cagliero, E.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Cense, B.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Chang, W.

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Chen, T.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Chen, Z.

Coker, J. G.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

Costa, V. P.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Cuartero, V.

A. Mendivil, V. Cuartero, and M. P. Mendivil, "Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study," Br. J. Ophthalmol. l 79, 413-416 (1995).
[CrossRef]

de Boer, J.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

de Boer, J. F.

de Jong, T. V. P.

C. W. C. Klaver, C. W. R. Wolfs, R. J. Vingerling, and T. V. P. de Jong, "Age-specific prevalence and causes of blindness and visual impairment in an older population," Arch. Ophthalmol. 116, 653-658 (2007).

Duker, J. S.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

Fabritius, T.

Feke, G. T.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Fercher, A. F.

Flammer, J.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

J. Flammer, "The vascular concept of glaucoma," Surv. Ophthalmol. 38, S3-S6 (1994).

Flotte, T.

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Fujimoto, J. G.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Fujioka, S.

S. Fujioka, K. Karashima, N. Nishikawa, and Y. Saito, "Correlation between higher blood flow velocity in the central retinal vein than in the central retinal artery and severity of nonproliferative diabetic retinopathy," Jpn. J. Ophthalmol. 50, 312-317 (2006).
[CrossRef]

Fujomoto, J. G.

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

Gil-Flamer, J.

Y. Wang, A. Lu, J. Gil-Flamer, O. Tan, D. Huang, "Measurement of total blood flow in the normal human retina using Doppler Fourier domain optical coherence tomography," Br. J. Ophthalmol. (in press).

Gordon, M.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Gregori, G.

Gregory, K.

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Grunwald, J. E.

C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Vis. Sci. 26, 1124-1132 (1985).

Guven, D.

D. Guven, H. Ozdemir, and B. Hasanreisoglu, "Hemodynamic alterations in diabetic retinopathy," Ophthalmology 103, 1245-1249 (1996).

Hardarson, S. H.

C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
[CrossRef]

Hasanreisoglu, B.

D. Guven, H. Ozdemir, and B. Hasanreisoglu, "Hemodynamic alterations in diabetic retinopathy," Ophthalmology 103, 1245-1249 (1996).

Hee, M. R.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Hertzmark, E.

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

Hitzenberger, C. K.

Huang, D.

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
[CrossRef]

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Y. Wang, A. Lu, J. Gil-Flamer, O. Tan, D. Huang, "Measurement of total blood flow in the normal human retina using Doppler Fourier domain optical coherence tomography," Br. J. Ophthalmol. (in press).

Izatt, J. A.

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
[CrossRef]

B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomed. Opt. 12, 041214 (2007).
[CrossRef]

S. Yazdanfar, A. M. Rollins, and J. A. Izatt, "In vivo imaging of human retinal flow dynamics by color Doppler optical coherence tomography," Arch. Ophthalmol. 121, 235-239 (2003).

S. Yazdanfar, A. M. Rollins, and J. A. Izatt. "Imaging and velocity of the human retinal circulation with color Doppler optical coherence tomography," Opt. Lett. 25, 1448-1450 (2000).
[CrossRef]

J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, J. K. Barton, and A. J. Welch. "In vivo bidirectional color Doppler flow imaging of picoliter blood volumes using optical coherence tomography," Opt. Lett. 22, 1439-1441 (1997).
[CrossRef]

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

Jiao, S.

Karashima, K.

S. Fujioka, K. Karashima, N. Nishikawa, and Y. Saito, "Correlation between higher blood flow velocity in the central retinal vein than in the central retinal artery and severity of nonproliferative diabetic retinopathy," Jpn. J. Ophthalmol. 50, 312-317 (2006).
[CrossRef]

Kerr, J.

J. Kerr, P. Nelson, and C. O’Brien. "A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension," Am. J. Ophthalmol. 126, 42-51 (1998).
[CrossRef]

Klaver, C. W. C.

C. W. C. Klaver, C. W. R. Wolfs, R. J. Vingerling, and T. V. P. de Jong, "Age-specific prevalence and causes of blindness and visual impairment in an older population," Arch. Ophthalmol. 116, 653-658 (2007).

Klein, R.

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

Krieqlstein, G. K.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Kulkarni, M. D.

Lasser, T.

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

Leitgeb, R. A.

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

R. A. Leitgeb, L. Schmetterer, C. K. Hitzenberger, A. F. Fercher, F. Berisha, M. Wojtkowski, and T. Bajraszewski, "Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography," Opt. Lett. 29, 171-173 (2004).
[CrossRef]

Lin, C. P.

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Lo, S.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Lorenzi, M.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Lu, A.

Y. Wang, A. Lu, J. Gil-Flamer, O. Tan, D. Huang, "Measurement of total blood flow in the normal human retina using Doppler Fourier domain optical coherence tomography," Br. J. Ophthalmol. (in press).

MacKinnon, J. R.

J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
[CrossRef]

Makita, S.

McKillop, G.

J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
[CrossRef]

McMeel, J. W.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Mendivil, A.

A. Mendivil, V. Cuartero, and M. P. Mendivil, "Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study," Br. J. Ophthalmol. l 79, 413-416 (1995).
[CrossRef]

Mendivil, M. P.

A. Mendivil, V. Cuartero, and M. P. Mendivil, "Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study," Br. J. Ophthalmol. l 79, 413-416 (1995).
[CrossRef]

Michaely, R.

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

Milner, T. E.

Mok, A.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Munoz, B.

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

Nassif, N.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Nathan, D. M.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Nelson, J. S.

Nelson, P.

J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
[CrossRef]

J. Kerr, P. Nelson, and C. O’Brien. "A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension," Am. J. Ophthalmol. 126, 42-51 (1998).
[CrossRef]

Nishikawa, N.

S. Fujioka, K. Karashima, N. Nishikawa, and Y. Saito, "Correlation between higher blood flow velocity in the central retinal vein than in the central retinal artery and severity of nonproliferative diabetic retinopathy," Jpn. J. Ophthalmol. 50, 312-317 (2006).
[CrossRef]

O’Brien, C.

J. Kerr, P. Nelson, and C. O’Brien. "A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension," Am. J. Ophthalmol. 126, 42-51 (1998).
[CrossRef]

O'Brien, C.

J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
[CrossRef]

Orgul, S.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Orzalesi, N.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Ozdemir, H.

D. Guven, H. Ozdemir, and B. Hasanreisoglu, "Hemodynamic alterations in diabetic retinopathy," Ophthalmology 103, 1245-1249 (1996).

Park, B.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Pedut-Kloizman, T.

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

Pekar, J.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Petrig, B. L.

C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Vis. Sci. 26, 1124-1132 (1985).

Pierce, M. C.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Pitler, L.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Pournaras, C. J.

C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
[CrossRef]

Puliafito, C. A.

H. Wehbe, M. Ruggeri, S. Jiao, G. Gregori, C. A. Puliafito, and W. Zhao, "Automatic retinal blood flow calculation using spectral domain optical coherence tomography," Opt. Express 15, 15193-15206 (2007).
[CrossRef]

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Qi, B.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Reichel, E.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

Renard, J. P.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Riva, C. E.

C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
[CrossRef]

C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Vis. Sci. 26, 1124-1132 (1985).

Rodriguez, J.

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

Rollins, A. M.

S. Yazdanfar, A. M. Rollins, and J. A. Izatt, "In vivo imaging of human retinal flow dynamics by color Doppler optical coherence tomography," Arch. Ophthalmol. 121, 235-239 (2003).

S. Yazdanfar, A. M. Rollins, and J. A. Izatt. "Imaging and velocity of the human retinal circulation with color Doppler optical coherence tomography," Opt. Lett. 25, 1448-1450 (2000).
[CrossRef]

Ruggeri, M.

Rungger-Brändle, E.

C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
[CrossRef]

Saito, Y.

S. Fujioka, K. Karashima, N. Nishikawa, and Y. Saito, "Correlation between higher blood flow velocity in the central retinal vein than in the central retinal artery and severity of nonproliferative diabetic retinopathy," Jpn. J. Ophthalmol. 50, 312-317 (2006).
[CrossRef]

Sanchez, R.

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

Saxer, C.

Schaumberg, D. A.

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Schmetterer, L.

Schuman, J. S.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Serra, L. M.

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Shen, Q.

Shuman, J. S.

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

Sinclair, S. H.

C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Vis. Sci. 26, 1124-1132 (1985).

Snyder, R.

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

Stefansson, E.

C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
[CrossRef]

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Stinson, W. G.

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Swa, K.

J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
[CrossRef]

Swanson, E. A.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Tan, O.

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
[CrossRef]

Y. Wang, A. Lu, J. Gil-Flamer, O. Tan, D. Huang, "Measurement of total blood flow in the normal human retina using Doppler Fourier domain optical coherence tomography," Br. J. Ophthalmol. (in press).

Tearney, G.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Villiger, M. L.

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

Vingerling, R. J.

C. W. C. Klaver, C. W. R. Wolfs, R. J. Vingerling, and T. V. P. de Jong, "Age-specific prevalence and causes of blindness and visual impairment in an older population," Arch. Ophthalmol. 116, 653-658 (2007).

Vitkin, I.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Wang, X. J.

Wang, Y.

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
[CrossRef]

Y. Wang, A. Lu, J. Gil-Flamer, O. Tan, D. Huang, "Measurement of total blood flow in the normal human retina using Doppler Fourier domain optical coherence tomography," Br. J. Ophthalmol. (in press).

Wehbe, H.

Welch, A. J.

West, K. S.

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

White, B. R.

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Wilkins, J. R.

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

Wilson, B.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Wojtkowski, M.

Wolfs, C. W. R.

C. W. C. Klaver, C. W. R. Wolfs, R. J. Vingerling, and T. V. P. de Jong, "Age-specific prevalence and causes of blindness and visual impairment in an older population," Arch. Ophthalmol. 116, 653-658 (2007).

Wong, C.

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

Xiang, S.

Yang, V. X. D.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Yasuno, Y.

Yazdanfar, S.

Yue, E. S.

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

Zawadzki, R. J.

B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomed. Opt. 12, 041214 (2007).
[CrossRef]

Zhao, M.

B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomed. Opt. 12, 041214 (2007).
[CrossRef]

Zhao, W.

Zhao, Y.

Acta Ophthalmol. Scand. (1)

J. R. MacKinnon, G. McKillop, C. O'Brien, K. Swa, Z. Butt, and P. Nelson, "Colour Doppler imaging of the ocular circulation in diabetic retinopathy," Acta Ophthalmol. Scand. 78, 386-389 (2000).
[CrossRef]

Am. J. Ophthalmol. (1)

J. Kerr, P. Nelson, and C. O’Brien. "A comparison of ocular blood flow in untreated primary open-angle glaucoma and ocular hypertension," Am. J. Ophthalmol. 126, 42-51 (1998).
[CrossRef]

Arch. Ophthalmol. (3)

C. W. C. Klaver, C. W. R. Wolfs, R. J. Vingerling, and T. V. P. de Jong, "Age-specific prevalence and causes of blindness and visual impairment in an older population," Arch. Ophthalmol. 116, 653-658 (2007).

J. S. Shuman, M. R. Hee, C. A. Puliafito, C. Wong, T. Pedut-Kloizman, C. P. Lin, E. Hertzmark, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Quantification of nerve fiber layer thickness in normal and glaucomatous eyes using optical coherence tomography," Arch. Ophthalmol. 113, 586-596 (1995).

S. Yazdanfar, A. M. Rollins, and J. A. Izatt, "In vivo imaging of human retinal flow dynamics by color Doppler optical coherence tomography," Arch. Ophthalmol. 121, 235-239 (2003).

Br. J. Ophthalmol. (1)

Y. Wang, A. Lu, J. Gil-Flamer, O. Tan, D. Huang, "Measurement of total blood flow in the normal human retina using Doppler Fourier domain optical coherence tomography," Br. J. Ophthalmol. (in press).

Br. J. Ophthalmol. l (1)

A. Mendivil, V. Cuartero, and M. P. Mendivil, "Ocular blood flow velocities in patients with proliferative diabetic retinopathy and healthy volunteers: a prospective study," Br. J. Ophthalmol. l 79, 413-416 (1995).
[CrossRef]

Curr. Opin. Ophthalmol. (1)

J. S. Shuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujomoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Curr. Opin. Ophthalmol. 6, 89-95 (1995).

Diabetes Care (1)

K. S. West, R. Klein, J. Rodriguez, B. Munoz, T. A. Broman, R. Sanchez, and R. Snyder, "Diabetes and diabetic retinopathy in a Mexican-American population," Diabetes Care 24, 1204-1209 (2001).
[CrossRef]

Diabetologia (1)

M. Lorenzi, G. T. Feke, E. Cagliero, L. Pitler, D. A. Schaumberg, F. Berisha, D. M. Nathan, and J. W. McMeel, "Retinal haemodynamics in individuals with well-controlled type 1 diabetes," Diabetologia 51, 361-364 (2008).
[CrossRef]

Invest. Ophthalmol. Vis. Sci. (1)

C. E. Riva, J. E. Grunwald, S. H. Sinclair, and B. L. Petrig, "Blood velocity and volumetric flow rate in human retinal vessels," Invest. Ophthalmol. Vis. Sci. 26, 1124-1132 (1985).

J. Biomed Opt. (1)

R. Michaely, A. H. Bachmann, M. L. Villiger, C. Blatter, T. Lasser and R. A. Leitgeb, "Vectorial reconstruction of retinal blood flow in three dimensions measured with high resolution resonant Doppler Fourier domain optical coherence tomography," J. Biomed Opt. 12, 041213 (2007).
[CrossRef]

J. Biomed. Opt. (3)

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "In vivo total retinal blood flow measurement by Fourier domain Doppler optical coherence tomography," J. Biomed. Opt. 12, 041215 (2007).
[CrossRef]

Y. Wang, B. A. Bower, J. A. Izatt, O. Tan, and D. Huang, "Retinal blood flow measurement by circumpapillary Fourier domain Doppler optical coherence," J. Biomed. Opt. 13, 064003 (2008).
[CrossRef]

B. A. Bower, M. Zhao, R. J. Zawadzki, and J. A. Izatt, "Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation," J. Biomed. Opt. 12, 041214 (2007).
[CrossRef]

Jpn. J. Ophthalmol. (1)

S. Fujioka, K. Karashima, N. Nishikawa, and Y. Saito, "Correlation between higher blood flow velocity in the central retinal vein than in the central retinal artery and severity of nonproliferative diabetic retinopathy," Jpn. J. Ophthalmol. 50, 312-317 (2006).
[CrossRef]

Ophthalmic Res. (1)

Q1. Jr. P. S. Garcia, P. T. Garcia, and R. B. Rosen, "Retinal blood flow in the normal human eye using the canon laser blood flowmeter," Ophthalmic Res. 34, 295-299 (2002).
[CrossRef]

Ophthalmology (4)

D. Guven, H. Ozdemir, and B. Hasanreisoglu, "Hemodynamic alterations in diabetic retinopathy," Ophthalmology 103, 1245-1249 (1996).

M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of macular holes," Ophthalmology 102, 748-756 (1995).

C. A. Puliafito, M. R. Hee, C. P. Lin, E. Reichel, J. S. Schuman, J. S. Duker, J. A. Izatt, E. A. Swanson, and J. G. Fujimoto, "Imaging of macular diseases with optical coherence tomography," Ophthalmology 102, 217-229 (1995).

M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103, 1260-1270 (1996).

Opt. Express (1)

Opt. Express. (2)

V. X. D. Yang, M. Gordon, E. S. Yue, S. Lo, B. Qi, J. Pekar, A. Mok, B. Wilson, and I. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part II): Imaging in vivo cardiac dynamic of Xenopus Laevis," Opt. Express. 11, 1650-1658 (2003).

B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. Park, G. Tearney, B. Bouma, T. Chen, and J. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express. 11, 3490-3497 (2003).

Opt. Lett. (6)

Prog Retin. Eye Res. (1)

J. Flammer, S. Orgul, V. P. Costa, N. Orzalesi, G. K. Krieqlstein, L. M. Serra, J. P. Renard, and E. Stefansson, "The impact of ocular blood flow in glaucoma," Prog Retin. Eye Res. 21, 359-393 (2002).
[CrossRef]

Prog. Retin. Eye Res. (1)

C. J. Pournaras, E. Rungger-Brändle, C. E. Riva, S. H. Hardarson, and E. Stefansson, "Regulation of retinal blood flow in health and disease," Prog. Retin. Eye Res. 27, 284-330 (2008).
[CrossRef]

Science (1)

D. Huang, D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254, 1178-1181 (1991).
[CrossRef]

Surv. Ophthalmol. (1)

J. Flammer, "The vascular concept of glaucoma," Surv. Ophthalmol. 38, S3-S6 (1994).

Other (1)

H. M. Wehbe, M. Ruggeri, S. Jiao, G. Gregori, C. A. Puliafito, and W. Zhao, "Calibration of blood flow measurement with spectral domain optical coherence tomography," in Biomedical Optics, OSA Technical Digest (CD) (Optical Society of America, 2008), paper BMD75.

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Datasets

Datasets associated with ISP articles are stored in an online database called MIDAS. Clicking a "View" link in an OSA ISP article will launch the ISP software (if installed) and pull the relevant data from MIDAS. Visit MIDAS to browse and download the datasets directly. A package containing the PDF article and full datasets is available in MIDAS for offline viewing.

Questions or Problems? See the ISP FAQ. Already used the ISP software? Take a quick survey to tell us what you think.

Metrics