Abstract

“Diffuse correlation spectroscopy” (DCS) is a technology for non-invasive transcranial measurement of cerebral blood flow (CBF) that can be hybridized with “near-infrared spectroscopy” (NIRS). Taken together these methods hold potential for monitoring hemodynamics in stroke patients. We explore the utility of DCS and NIRS to measure effects of head-of-bed (HOB) positioning at 30°, 15°, 0°, -5° and 0° angles in patients with acute ischemic stroke affecting frontal cortex and in controls. HOB positioning significantly altered CBF, oxy-hemoglobin (HbO2) and total-hemoglobin (THC) concentrations. Moreover, the presence of an ipsilateral infarct was a significant effect for all parameters. Results are consistent with the notion of impaired CBF autoregulation in the infarcted hemisphere.

© 2009 Optical Society of America

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2008 (3)

W. M. Kuebler, “How NIR is the future in blood flow monitoring?” J Appl Physiol 104(4), 905–906 (2008).
[Crossref] [PubMed]

D. Hargroves, R. Tallis, V. Pomeroy, and A. Bhalla, “The influence of positioning upon cerebral oxygenation after acute stroke: a pilot study,” Age Ageing 37(5), 581–585 (2008).
[Crossref] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

2007 (9)

G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

A. Chieregato, A. Tanfani, C. Compagnone, R. Pascarella, L. Targa, and E. Fainardi, “Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure,” Neurosurgery 60(1), 115–123 (2007).
[Crossref] [PubMed]

C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
[Crossref]

T. Asil, U. Utku, K. Balci, and I. Uzunca, “Changing cerebral blood flow velocity by transcranial Doppler during head up tilt in patients with diabetes mellitus,” Clin Neurol Neurosurg 109(1), 1–6 (2007).
[Crossref]

M. S. Damian and R. Schlosser, “Bilateral near infrared spectroscopy in space-occupying middle cerebral artery stroke,” Neurocritical Care 6(3), 165–173 (2007).
[Crossref] [PubMed]

R. Carandang and D. W. Krieger, “Near infrared spectroscopy: finding utility in malignant hemispheric stroke,” Neurocritical Care 6(3), 161–164 (2007).
[Crossref] [PubMed]

E. M. C. Hillman, “Optical brain imaging in vivo: techniques and applications from animal to man,” Journal of Biomedical Optics 12(5) (2007).
[Crossref] [PubMed]

2006 (4)

A. D. Lopez, C. D. Mathers, M. Ezzati, D. T. Jamison, and C. J. L. Murray, “Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data,” The Lancet 367(9524), 1747–1757 (2006).
[Crossref]

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
[Crossref]

2005 (8)

T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
[Crossref] [PubMed]

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
[Crossref]

A. W. Wojner-Alexander, Z. Garami, O. Y. Chernyshev, and A. V. Alexandrov, “Heads down: flat positioning improves blood flow velocity in acute ischemic stroke,” Neurology 64(8), 1354–1357 (2005).
[Crossref] [PubMed]

W. K. Paula, “Heads down: flat positioning improves blood flow velocity in acute ischemic stroke,” Neurology 65(9), 1514–1514 (2005).
[PubMed]

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

A. Liebert, H. Wabnitz, J. Steinbrink, M. Moller, R. Macdonald, H. Rinneberg, A. Villringer, and H. Obrig, “Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance,” Neuroimage 24, 426–35 (2005).
[Crossref] [PubMed]

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
[Crossref]

G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
[Crossref] [PubMed]

2004 (4)

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
[Crossref] [PubMed]

C. Terborg, S. Bramer, S. Harscher, M. Simon, and O. W. Witte, “Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green,” J Neurol Neurosurg Psychiatry 75(1), 38–42 (2004).
[PubMed]

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

R. E. Latchaw, “Cerebral perfusion imaging in acute stroke,” J Vasc Interv Radiol 15(1 Pt 2), 29–46 (2004).

2003 (6)

S. L. Dawson, R. B. Panerai, and J. F. Potter, “Serial changes in static and dynamic cerebral autoregulation after acute ischaemic stroke,” Cerebrovasc Dis 16(1), 69–75 (2003).
[Crossref] [PubMed]

I. Miyai, H. Yagura, M. Hatakenaka, I. Oda, I. Konishi, and K. Kubota, “Longitudinal Optical Imaging Study for Locomotor Recovery After Stroke,” Stroke 34(12), 2866–2870 (2003).
[Crossref] [PubMed]

C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
[PubMed]

E. Okada and D. T. Delpy, “Near-Infrared light propagation in an adult head model. II. Effect of superficial tissue thickness on the sensitivity of the near-infrared spectroscopy signal,” Appl. Opt. 42, 2915–21 (2003).
[Crossref] [PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Tomography of Cerebral Blood Flow, Oxygenation and Metabolism in Rat During Focal Ischemia,” J. Cereb. Blood Flow Metab. 23, 911–24 (2003).
[Crossref] [PubMed]

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” NeuroImage 18, 865–79 (2003).
[Crossref] [PubMed]

2002 (3)

H. Kato, M. Izumiyama, H. Koizumi, A. Takahashi, and Y. Itoyama, “Near-Infrared Spectroscopic Topography as a Tool to Monitor Motor Reorganization After Hemiparetic Stroke: A Comparison With Functional MRI,” Stroke 33(8), 2032–2036 (2002).
[Crossref] [PubMed]

P. Bönöczk, G. Panczel, and Z. Nagy, “Vinpocetine increases cerebral blood flow and oxygenation in stroke patients: a near infrared spectroscopy and transcranial Doppler study,” European Journal of Ultrasound 15(1–2), 85–91 (2002).
[Crossref] [PubMed]

S. Schwarz, D. Georgiadis, A. Aschoff, and S. Schwab, “Effects of body position on intracranial pressure and cerebral perfusion in patients with large hemispheric stroke,” Stroke 33(2), 497–501 (2002).
[Crossref] [PubMed]

2001 (6)

J. C. Baron, “Mapping the ischaemic penumbra with PET: a new approach,” Brain 124(Pt 1), 2–4 (2001).
[Crossref] [PubMed]

R. R. Pindzola, J. R. Balzer, E. M. Nemoto, S. Goldstein, and H. Yonas, “Cerebrovascular reserve in patients with carotid occlusive disease assessed by stable xenon-enhanced ct cerebral blood flow and transcranial Doppler,” Stroke 32(8), 1811–1817 (2001).
[Crossref] [PubMed]

D. A. Boas, T. Gaudette, G. Strangman, X. Cheng, J. J. A. Marota, and J. B. Mandeville, “The Accuracy of Near Infrared Spectroscopy and Imaging during Focal Changes in Cerebral Hemodynamics,” NeuroImage 13, 76–90 (2001).
[Crossref] [PubMed]

C. Cheung, J. P. Culver, K. Takahashi, J. H. Greenberg, and A. G. Yodh, “In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies,” Phys. Med. and Biol. 46(8), 2053–2065 (2001).
[Crossref]

J. Steinbrink, H. Wabnitz, H. Obrig, A. Villringer, and H. Rinneberg, “Determining changes in NIR absorption using a layered model of the human head,” Phys Med Biol 46(3), 879–96. (2001).
[Crossref] [PubMed]

J. Kelly, A. Rudd, R. Lewis, and B. J. Hunt, “Venous thromboembolism after acute stroke,” Stroke 32(1), 262–267 (2001).
[Crossref] [PubMed]

2000 (5)

P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
[Crossref] [PubMed]

L. A. Lipsitz, S. Mukai, J. Hamner, M. Gagnon, and V. Babikian, “Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension,” Stroke 31(8), 1897–1903 (2000).
[Crossref] [PubMed]

L. B. Goldstein, “Should antihypertensive therapies be given to patients with acute ischemic stroke?” Drug Saf 22(1), 13–18 (2000).
[Crossref] [PubMed]

J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
[Crossref] [PubMed]

E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
[Crossref] [PubMed]

1999 (2)

F. Vernieri, N. Rosato, F. Pauri, F. Tibuzzi, F. Passarelli, and P. M. Rossini, “Near Infrared Spectroscopy and Transcranial Doppler in Monohemispheric Stroke,” Eur Neurol 41(3), 159–162 (1999).
[Crossref] [PubMed]

A. V. Alexandrov, A. M. Demchuk, T. H. Wein, and J. C. Grotta, “Yield of transcranial Doppler in acute cerebral ischemia,” Stroke 30(8), 1604–1609 (1999).
[Crossref] [PubMed]

1998 (4)

C. Benesch and R. Holloway, “Economic Impact of Stroke and Implications for Interventions.” CNS Drugs 9, 19 (1998).
[Crossref]

K. Sakatani, Y. Xie, W. Lichty, S. Li, and H. Zuo, “Language-Activated Cerebral Blood Oxygenation and Hemodynamic Changes of the Left Prefrontal Cortex in Poststroke Aphasic Patients : A Near-Infrared Spectroscopy Study,” Stroke 29(7), 1299–1304 (1998).
[Crossref] [PubMed]

S. I. Kamran, D. Downey, and R. L. Ruff, “Pneumatic sequential compression reduces the risk of deep vein thrombosis in stroke patients,” Neurology 50(6), 1683–1688 (1998).
[PubMed]

M. Kohl, C. Nolte, H. R. Heekeren, S. Horst, U. Scholz, H. Obrig, and A. Villringer, “Determination of the wavelength dependence of the differential pathlength factor from near-infrared pulse signals,” Phys Med Biol 43(6), 1771–82 (1998).
[Crossref] [PubMed]

1997 (3)

R. Fernandez-Crehuet, C. Diaz-Molina, J. de Irala, D. Martinez-Concha, I. Salcedo-Leal, and J. Masa-Calles, “Nosocomial infection in an intensive-care unit: identification of risk factors.” Infect Control Hosp Epidemiol 18(12), 825–30 (1997).
[Crossref]

D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997).
[Crossref]

A. Villringer and B. Chance, “Non-invasive optical spectroscopy and imaging of human brain function,” Trends Neurosci. 20, 435–442 (1997).
[Crossref] [PubMed]

1995 (2)

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and Imaging with Diffusing Temporal Field Correlations,” Phys Rev Lett 75(9), 1855–1858 (1995).
[Crossref] [PubMed]

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
[Crossref] [PubMed]

1994 (1)

K. A. Hossmann, “Viability thresholds and the penumbra of focal ischemia,” Ann Neurol 36(4), 557–565 (1994).
[Crossref] [PubMed]

1993 (1)

H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
[Crossref] [PubMed]

1992 (2)

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys Med Biol 37(7), 1531–60 (1992).
[Crossref] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[Crossref] [PubMed]

1988 (3)

D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys Med Biol 33, 1433–1442 (1988).
[Crossref] [PubMed]

M. Cope and D. T. Delpy, “System for long-term measurement of cerebral blood flow and tissue oxygenation on newborn infants by infra-red transillumination.” Med Biol Eng Comput 26, 289–294 (1988).
[Crossref] [PubMed]

D. J. Pine, D. A. Weitz, P. M. Chaikin, and Herbolzheimer, “Diffusing-wave spectroscopy,” Phys. Rev. Lett. 60, 1134–1137 (1988).
[Crossref] [PubMed]

1987 (1)

G. Maret and P. E. Wolf, “Multiple light scattering from disordered media. The effect of brownian motion of scatterers,” Z. Phys. B 65, 409–413 (1987).
[Crossref]

1986 (1)

C. C. Bishop, S. Powell, D. Rutt, and N. L. Browse, “Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study,” Stroke 17, 913–915 (1986).
[Crossref] [PubMed]

1981 (1)

J. Astrup, B. K. Siesjo, and L. Symon, “Thresholds in cerebral ischemia - the ischemic penumbra,” Stroke 12(6), 723–725 (1981).
[Crossref] [PubMed]

1974 (1)

H. Akaike, “A new look at the statistical model identification,” Automatic Control, IEEE Transactions on 19(6), 716–723 (1974).
[Crossref]

1905 (1)

A. Einstein, “On the motion of small particles suspended in liquids at rest required by the molecular-kinetic theory of heat,” Annalen der Physik 17, 549–60 (1905).
[Crossref]

Adams, H. P.

H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
[Crossref] [PubMed]

Adams, J.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Akaike, H.

H. Akaike, “A new look at the statistical model identification,” Automatic Control, IEEE Transactions on 19(6), 716–723 (1974).
[Crossref]

Alberts, M. J.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Alexandrov, A. V.

A. W. Wojner-Alexander, Z. Garami, O. Y. Chernyshev, and A. V. Alexandrov, “Heads down: flat positioning improves blood flow velocity in acute ischemic stroke,” Neurology 64(8), 1354–1357 (2005).
[Crossref] [PubMed]

A. V. Alexandrov, A. M. Demchuk, T. H. Wein, and J. C. Grotta, “Yield of transcranial Doppler in acute cerebral ischemia,” Stroke 30(8), 1604–1609 (1999).
[Crossref] [PubMed]

Alsop, D. C.

J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
[Crossref] [PubMed]

Arger, P. H.

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

Arridge, S.

D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys Med Biol 33, 1433–1442 (1988).
[Crossref] [PubMed]

Arridge, S. R.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[Crossref] [PubMed]

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys Med Biol 37(7), 1531–60 (1992).
[Crossref] [PubMed]

Aschoff, A.

S. Schwarz, D. Georgiadis, A. Aschoff, and S. Schwab, “Effects of body position on intracranial pressure and cerebral perfusion in patients with large hemispheric stroke,” Stroke 33(2), 497–501 (2002).
[Crossref] [PubMed]

Asil, T.

T. Asil, U. Utku, K. Balci, and I. Uzunca, “Changing cerebral blood flow velocity by transcranial Doppler during head up tilt in patients with diabetes mellitus,” Clin Neurol Neurosurg 109(1), 1–6 (2007).
[Crossref]

Astrup, J.

J. Astrup, B. K. Siesjo, and L. Symon, “Thresholds in cerebral ischemia - the ischemic penumbra,” Stroke 12(6), 723–725 (1981).
[Crossref] [PubMed]

Babikian, V.

L. A. Lipsitz, S. Mukai, J. Hamner, M. Gagnon, and V. Babikian, “Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension,” Stroke 31(8), 1897–1903 (2000).
[Crossref] [PubMed]

Balci, K.

T. Asil, U. Utku, K. Balci, and I. Uzunca, “Changing cerebral blood flow velocity by transcranial Doppler during head up tilt in patients with diabetes mellitus,” Clin Neurol Neurosurg 109(1), 1–6 (2007).
[Crossref]

Balzer, J. R.

R. R. Pindzola, J. R. Balzer, E. M. Nemoto, S. Goldstein, and H. Yonas, “Cerebrovascular reserve in patients with carotid occlusive disease assessed by stable xenon-enhanced ct cerebral blood flow and transcranial Doppler,” Stroke 32(8), 1811–1817 (2001).
[Crossref] [PubMed]

Barbier, E.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

Baron, J. C.

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

J. C. Baron, “Mapping the ischaemic penumbra with PET: a new approach,” Brain 124(Pt 1), 2–4 (2001).
[Crossref] [PubMed]

Bates, D. M.

J. C. Pinheiro and D. M. Bates, Mixed-effects models in S and S-Plus (Springer, New York, 2000).
[Crossref]

Bendixen, B. H.

H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
[Crossref] [PubMed]

Benesch, C.

C. Benesch and R. Holloway, “Economic Impact of Stroke and Implications for Interventions.” CNS Drugs 9, 19 (1998).
[Crossref]

Bhalla, A.

D. Hargroves, R. Tallis, V. Pomeroy, and A. Bhalla, “The influence of positioning upon cerebral oxygenation after acute stroke: a pilot study,” Age Ageing 37(5), 581–585 (2008).
[Crossref] [PubMed]

Bhatt, D. L.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Biller, J.

H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
[Crossref] [PubMed]

Bishop, C. C.

C. C. Bishop, S. Powell, D. Rutt, and N. L. Browse, “Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study,” Stroke 17, 913–915 (1986).
[Crossref] [PubMed]

Boas, D. A.

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” NeuroImage 18, 865–79 (2003).
[Crossref] [PubMed]

D. A. Boas, T. Gaudette, G. Strangman, X. Cheng, J. J. A. Marota, and J. B. Mandeville, “The Accuracy of Near Infrared Spectroscopy and Imaging during Focal Changes in Cerebral Hemodynamics,” NeuroImage 13, 76–90 (2001).
[Crossref] [PubMed]

D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997).
[Crossref]

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and Imaging with Diffusing Temporal Field Correlations,” Phys Rev Lett 75(9), 1855–1858 (1995).
[Crossref] [PubMed]

Bönöczk, P.

P. Bönöczk, G. Panczel, and Z. Nagy, “Vinpocetine increases cerebral blood flow and oxygenation in stroke patients: a near infrared spectroscopy and transcranial Doppler study,” European Journal of Ultrasound 15(1–2), 85–91 (2002).
[Crossref] [PubMed]

Borbely, K.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

Bosche, B.

C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
[Crossref]

Bramer, S.

C. Terborg, S. Bramer, S. Harscher, M. Simon, and O. W. Witte, “Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green,” J Neurol Neurosurg Psychiatry 75(1), 38–42 (2004).
[PubMed]

Brass, L.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Brinker, G.

C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
[Crossref]

Browse, N. L.

C. C. Bishop, S. Powell, D. Rutt, and N. L. Browse, “Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study,” Stroke 17, 913–915 (1986).
[Crossref] [PubMed]

Buckley, E. M.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Buerk, D. G.

C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
[PubMed]

Burnett, M. G.

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
[Crossref] [PubMed]

Busch, T. M.

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
[Crossref] [PubMed]

Butler, J.

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

Caille, J. M.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

Campbell, L. E.

D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and Imaging with Diffusing Temporal Field Correlations,” Phys Rev Lett 75(9), 1855–1858 (1995).
[Crossref] [PubMed]

Carandang, R.

R. Carandang and D. W. Krieger, “Near infrared spectroscopy: finding utility in malignant hemispheric stroke,” Neurocritical Care 6(3), 161–164 (2007).
[Crossref] [PubMed]

Cerussi, A.

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

Chaikin, P. M.

D. J. Pine, D. A. Weitz, P. M. Chaikin, and Herbolzheimer, “Diffusing-wave spectroscopy,” Phys. Rev. Lett. 60, 1134–1137 (1988).
[Crossref] [PubMed]

Chalela, J. A.

J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
[Crossref] [PubMed]

Chance, B.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
[Crossref]

A. Villringer and B. Chance, “Non-invasive optical spectroscopy and imaging of human brain function,” Trends Neurosci. 20, 435–442 (1997).
[Crossref] [PubMed]

Chatel, M.

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

Cheng, X.

D. A. Boas, T. Gaudette, G. Strangman, X. Cheng, J. J. A. Marota, and J. B. Mandeville, “The Accuracy of Near Infrared Spectroscopy and Imaging during Focal Changes in Cerebral Hemodynamics,” NeuroImage 13, 76–90 (2001).
[Crossref] [PubMed]

Chernyshev, O. Y.

A. W. Wojner-Alexander, Z. Garami, O. Y. Chernyshev, and A. V. Alexandrov, “Heads down: flat positioning improves blood flow velocity in acute ischemic stroke,” Neurology 64(8), 1354–1357 (2005).
[Crossref] [PubMed]

Cheung, C.

C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
[PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Tomography of Cerebral Blood Flow, Oxygenation and Metabolism in Rat During Focal Ischemia,” J. Cereb. Blood Flow Metab. 23, 911–24 (2003).
[Crossref] [PubMed]

C. Cheung, J. P. Culver, K. Takahashi, J. H. Greenberg, and A. G. Yodh, “In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies,” Phys. Med. and Biol. 46(8), 2053–2065 (2001).
[Crossref]

Chieregato, A.

A. Chieregato, A. Tanfani, C. Compagnone, R. Pascarella, L. Targa, and E. Fainardi, “Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure,” Neurosurgery 60(1), 115–123 (2007).
[Crossref] [PubMed]

Choe, R.

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
[Crossref] [PubMed]

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

Clemence, M.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
[Crossref] [PubMed]

Compagnone, C.

A. Chieregato, A. Tanfani, C. Compagnone, R. Pascarella, L. Targa, and E. Fainardi, “Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure,” Neurosurgery 60(1), 115–123 (2007).
[Crossref] [PubMed]

Cook, N. M.

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

Cope, M.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
[Crossref] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[Crossref] [PubMed]

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys Med Biol 37(7), 1531–60 (1992).
[Crossref] [PubMed]

M. Cope and D. T. Delpy, “System for long-term measurement of cerebral blood flow and tissue oxygenation on newborn infants by infra-red transillumination.” Med Biol Eng Comput 26, 289–294 (1988).
[Crossref] [PubMed]

D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys Med Biol 33, 1433–1442 (1988).
[Crossref] [PubMed]

Cucchiara, B. L.

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Culver, J. P.

C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
[PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Tomography of Cerebral Blood Flow, Oxygenation and Metabolism in Rat During Focal Ischemia,” J. Cereb. Blood Flow Metab. 23, 911–24 (2003).
[Crossref] [PubMed]

C. Cheung, J. P. Culver, K. Takahashi, J. H. Greenberg, and A. G. Yodh, “In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies,” Phys. Med. and Biol. 46(8), 2053–2065 (2001).
[Crossref]

Czerniecki, B. J.

T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
[Crossref] [PubMed]

Damian, M. S.

M. S. Damian and R. Schlosser, “Bilateral near infrared spectroscopy in space-occupying middle cerebral artery stroke,” Neurocritical Care 6(3), 165–173 (2007).
[Crossref] [PubMed]

Darcourt, J.

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

David, O.

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

Dawson, S. L.

S. L. Dawson, R. B. Panerai, and J. F. Potter, “Serial changes in static and dynamic cerebral autoregulation after acute ischaemic stroke,” Cerebrovasc Dis 16(1), 69–75 (2003).
[Crossref] [PubMed]

Delpy, D. T.

E. Okada and D. T. Delpy, “Near-Infrared light propagation in an adult head model. II. Effect of superficial tissue thickness on the sensitivity of the near-infrared spectroscopy signal,” Appl. Opt. 42, 2915–21 (2003).
[Crossref] [PubMed]

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
[Crossref] [PubMed]

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[Crossref] [PubMed]

S. R. Arridge, M. Cope, and D. T. Delpy, “The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis,” Phys Med Biol 37(7), 1531–60 (1992).
[Crossref] [PubMed]

D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys Med Biol 33, 1433–1442 (1988).
[Crossref] [PubMed]

M. Cope and D. T. Delpy, “System for long-term measurement of cerebral blood flow and tissue oxygenation on newborn infants by infra-red transillumination.” Med Biol Eng Comput 26, 289–294 (1988).
[Crossref] [PubMed]

Demchuk, A. M.

A. V. Alexandrov, A. M. Demchuk, T. H. Wein, and J. C. Grotta, “Yield of transcranial Doppler in acute cerebral ischemia,” Stroke 30(8), 1604–1609 (1999).
[Crossref] [PubMed]

Detre, J. A.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
[Crossref] [PubMed]

J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
[Crossref] [PubMed]

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

Diaz-Molina, C.

R. Fernandez-Crehuet, C. Diaz-Molina, J. de Irala, D. Martinez-Concha, I. Salcedo-Leal, and J. Masa-Calles, “Nosocomial infection in an intensive-care unit: identification of risk factors.” Infect Control Hosp Epidemiol 18(12), 825–30 (1997).
[Crossref]

Dick, F.

P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
[Crossref] [PubMed]

Dietsche, G.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
[Crossref]

Dillon, W. P.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

Dohmen, C.

C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
[Crossref]

Dousset, V.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

Downey, D.

S. I. Kamran, D. Downey, and R. L. Ruff, “Pneumatic sequential compression reduces the risk of deep vein thrombosis in stroke patients,” Neurology 50(6), 1683–1688 (1998).
[PubMed]

Du, J.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

Dunac, A.

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

Duncan, A.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
[Crossref] [PubMed]

Durduran, T.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
[Crossref]

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
[Crossref]

T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
[Crossref] [PubMed]

G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
[Crossref] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
[Crossref] [PubMed]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Tomography of Cerebral Blood Flow, Oxygenation and Metabolism in Rat During Focal Ischemia,” J. Cereb. Blood Flow Metab. 23, 911–24 (2003).
[Crossref] [PubMed]

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, “Non-Invasive Measurements of Tissue Hemodynamics with Hybrid Diffuse Optical Methods,” Ph.D. Dissertation, University of Pennsylvania (2004).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

Durkin, A.

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

Durning, S. M.

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

Eastwood, J. D.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

Edlow, B.

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

Edlow, B. L.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Edwards, A. D.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[Crossref] [PubMed]

Einstein, A.

A. Einstein, “On the motion of small particles suspended in liquids at rest required by the molecular-kinetic theory of heat,” Annalen der Physik 17, 549–60 (1905).
[Crossref]

Elbert, T.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
[Crossref]

Elwell, C. E.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
[Crossref] [PubMed]

Ernestus, R. I.

C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
[Crossref]

Essenpreis, M.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[Crossref] [PubMed]

Eucker, S.

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

Ezzati, M.

A. D. Lopez, C. D. Mathers, M. Ezzati, D. T. Jamison, and C. J. L. Murray, “Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data,” The Lancet 367(9524), 1747–1757 (2006).
[Crossref]

Fainardi, E.

A. Chieregato, A. Tanfani, C. Compagnone, R. Pascarella, L. Targa, and E. Fainardi, “Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure,” Neurosurgery 60(1), 115–123 (2007).
[Crossref] [PubMed]

Fernandez-Crehuet, R.

R. Fernandez-Crehuet, C. Diaz-Molina, J. de Irala, D. Martinez-Concha, I. Salcedo-Leal, and J. Masa-Calles, “Nosocomial infection in an intensive-care unit: identification of risk factors.” Infect Control Hosp Epidemiol 18(12), 825–30 (1997).
[Crossref]

Finlay, J. C.

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

Floyd, T.

G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

Fraker, D. L.

C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
[PubMed]

Franceschini, M. A.

G. Strangman, M. A. Franceschini, and D. A. Boas, “Factors affecting the accuracy of near-infrared spectroscopy concentration calculations for focal changes in oxygenation parameters,” NeuroImage 18, 865–79 (2003).
[Crossref] [PubMed]

Frangos, S.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

Frangos, S. K.

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Friess, S.

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

Furlan, A.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Furuya, D.

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
[Crossref]

J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Tomography of Cerebral Blood Flow, Oxygenation and Metabolism in Rat During Focal Ischemia,” J. Cereb. Blood Flow Metab. 23, 911–24 (2003).
[Crossref] [PubMed]

Gagnon, M.

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S. Schwarz, D. Georgiadis, A. Aschoff, and S. Schwab, “Effects of body position on intracranial pressure and cerebral perfusion in patients with large hemispheric stroke,” Stroke 33(2), 497–501 (2002).
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J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
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G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
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M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
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L. B. Goldstein, “Should antihypertensive therapies be given to patients with acute ischemic stroke?” Drug Saf 22(1), 13–18 (2000).
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J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
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H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
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M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

Grady, S. M.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

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C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
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M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
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T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
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J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Tomography of Cerebral Blood Flow, Oxygenation and Metabolism in Rat During Focal Ischemia,” J. Cereb. Blood Flow Metab. 23, 911–24 (2003).
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C. Cheung, J. P. Culver, K. Takahashi, J. H. Greenberg, and A. G. Yodh, “In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies,” Phys. Med. and Biol. 46(8), 2053–2065 (2001).
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M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

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A. V. Alexandrov, A. M. Demchuk, T. H. Wein, and J. C. Grotta, “Yield of transcranial Doppler in acute cerebral ischemia,” Stroke 30(8), 1604–1609 (1999).
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J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Hacke, W.

E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
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Hahn, S. M.

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
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Hamner, J.

L. A. Lipsitz, S. Mukai, J. Hamner, M. Gagnon, and V. Babikian, “Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension,” Stroke 31(8), 1897–1903 (2000).
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E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
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D. Hargroves, R. Tallis, V. Pomeroy, and A. Bhalla, “The influence of positioning upon cerebral oxygenation after acute stroke: a pilot study,” Age Ageing 37(5), 581–585 (2008).
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C. Terborg, S. Bramer, S. Harscher, M. Simon, and O. W. Witte, “Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green,” J Neurol Neurosurg Psychiatry 75(1), 38–42 (2004).
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M. Kohl, C. Nolte, H. R. Heekeren, S. Horst, U. Scholz, H. Obrig, and A. Villringer, “Determination of the wavelength dependence of the differential pathlength factor from near-infrared pulse signals,” Phys Med Biol 43(6), 1771–82 (1998).
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C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
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J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

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E. M. C. Hillman, “Optical brain imaging in vivo: techniques and applications from animal to man,” Journal of Biomedical Optics 12(5) (2007).
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C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
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C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
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J. Kelly, A. Rudd, R. Lewis, and B. J. Hunt, “Venous thromboembolism after acute stroke,” Stroke 32(1), 262–267 (2001).
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E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

Ichor, R.

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

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J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
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H. Kato, M. Izumiyama, H. Koizumi, A. Takahashi, and Y. Itoyama, “Near-Infrared Spectroscopic Topography as a Tool to Monitor Motor Reorganization After Hemiparetic Stroke: A Comparison With Functional MRI,” Stroke 33(8), 2032–2036 (2002).
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Izumiyama, M.

H. Kato, M. Izumiyama, H. Koizumi, A. Takahashi, and Y. Itoyama, “Near-Infrared Spectroscopic Topography as a Tool to Monitor Motor Reorganization After Hemiparetic Stroke: A Comparison With Functional MRI,” Stroke 33(8), 2032–2036 (2002).
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J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

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P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
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S. I. Kamran, D. Downey, and R. L. Ruff, “Pneumatic sequential compression reduces the risk of deep vein thrombosis in stroke patients,” Neurology 50(6), 1683–1688 (1998).
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H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
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J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
[Crossref] [PubMed]

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

Kato, H.

H. Kato, M. Izumiyama, H. Koizumi, A. Takahashi, and Y. Itoyama, “Near-Infrared Spectroscopic Topography as a Tool to Monitor Motor Reorganization After Hemiparetic Stroke: A Comparison With Functional MRI,” Stroke 33(8), 2032–2036 (2002).
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E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
[Crossref] [PubMed]

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J. Kelly, A. Rudd, R. Lewis, and B. J. Hunt, “Venous thromboembolism after acute stroke,” Stroke 32(1), 262–267 (2001).
[Crossref] [PubMed]

Kidwell, C.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Kilger, A.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
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Kim, M. N.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

Kofke, A.

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Kofke, W. A.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

Kohl, M.

M. Kohl, C. Nolte, H. R. Heekeren, S. Horst, U. Scholz, H. Obrig, and A. Villringer, “Determination of the wavelength dependence of the differential pathlength factor from near-infrared pulse signals,” Phys Med Biol 43(6), 1771–82 (1998).
[Crossref] [PubMed]

Koizumi, H.

H. Kato, M. Izumiyama, H. Koizumi, A. Takahashi, and Y. Itoyama, “Near-Infrared Spectroscopic Topography as a Tool to Monitor Motor Reorganization After Hemiparetic Stroke: A Comparison With Functional MRI,” Stroke 33(8), 2032–2036 (2002).
[Crossref] [PubMed]

Konishi, I.

I. Miyai, H. Yagura, M. Hatakenaka, I. Oda, I. Konishi, and K. Kubota, “Longitudinal Optical Imaging Study for Locomotor Recovery After Stroke,” Stroke 34(12), 2866–2870 (2003).
[Crossref] [PubMed]

Krieger, D. W.

R. Carandang and D. W. Krieger, “Near infrared spectroscopy: finding utility in malignant hemispheric stroke,” Neurocritical Care 6(3), 161–164 (2007).
[Crossref] [PubMed]

Kubota, K.

I. Miyai, H. Yagura, M. Hatakenaka, I. Oda, I. Konishi, and K. Kubota, “Longitudinal Optical Imaging Study for Locomotor Recovery After Stroke,” Stroke 34(12), 2866–2870 (2003).
[Crossref] [PubMed]

Kuebler, W. M.

W. M. Kuebler, “How NIR is the future in blood flow monitoring?” J Appl Physiol 104(4), 905–906 (2008).
[Crossref] [PubMed]

Langhorne, P.

P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
[Crossref] [PubMed]

Latchaw, R. E.

R. E. Latchaw, “Cerebral perfusion imaging in acute stroke,” J Vasc Interv Radiol 15(1 Pt 2), 29–46 (2004).

Lech, G.

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
[Crossref]

Lee, W. M.

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

Levine, J.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

Levine, J. M.

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Lewis, R.

J. Kelly, A. Rudd, R. Lewis, and B. J. Hunt, “Venous thromboembolism after acute stroke,” Stroke 32(1), 262–267 (2001).
[Crossref] [PubMed]

Li, J.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
[Crossref]

Li, S.

K. Sakatani, Y. Xie, W. Lichty, S. Li, and H. Zuo, “Language-Activated Cerebral Blood Oxygenation and Hemodynamic Changes of the Left Prefrontal Cortex in Poststroke Aphasic Patients : A Near-Infrared Spectroscopy Study,” Stroke 29(7), 1299–1304 (1998).
[Crossref] [PubMed]

Licht, D.

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

Licht, D. J.

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

Lichty, W.

K. Sakatani, Y. Xie, W. Lichty, S. Li, and H. Zuo, “Language-Activated Cerebral Blood Oxygenation and Hemodynamic Changes of the Left Prefrontal Cortex in Poststroke Aphasic Patients : A Near-Infrared Spectroscopy Study,” Stroke 29(7), 1299–1304 (1998).
[Crossref] [PubMed]

Liebert, A.

A. Liebert, H. Wabnitz, J. Steinbrink, M. Moller, R. Macdonald, H. Rinneberg, A. Villringer, and H. Obrig, “Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance,” Neuroimage 24, 426–35 (2005).
[Crossref] [PubMed]

Lipsitz, L. A.

L. A. Lipsitz, S. Mukai, J. Hamner, M. Gagnon, and V. Babikian, “Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension,” Stroke 31(8), 1897–1903 (2000).
[Crossref] [PubMed]

Loevner, L.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

Lopez, A. D.

A. D. Lopez, C. D. Mathers, M. Ezzati, D. T. Jamison, and C. J. L. Murray, “Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data,” The Lancet 367(9524), 1747–1757 (2006).
[Crossref]

Love, B. B.

H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
[Crossref] [PubMed]

Lustig, R.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

Lyden, P. D.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

MacDonald, J.

P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
[Crossref] [PubMed]

Macdonald, R.

A. Liebert, H. Wabnitz, J. Steinbrink, M. Moller, R. Macdonald, H. Rinneberg, A. Villringer, and H. Obrig, “Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance,” Neuroimage 24, 426–35 (2005).
[Crossref] [PubMed]

Mahagne, M. H.

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

Mahoney-Wilensky, E.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

Makonnen, S.

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

Maldjian, J. A.

J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
[Crossref] [PubMed]

Malkowicz, S. B.

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

Maloney-Wilensky, E.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

Mandeville, J. B.

D. A. Boas, T. Gaudette, G. Strangman, X. Cheng, J. J. A. Marota, and J. B. Mandeville, “The Accuracy of Near Infrared Spectroscopy and Imaging during Focal Changes in Cerebral Hemodynamics,” NeuroImage 13, 76–90 (2001).
[Crossref] [PubMed]

Maret, G.

J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
[Crossref]

G. Maret and P. E. Wolf, “Multiple light scattering from disordered media. The effect of brownian motion of scatterers,” Z. Phys. B 65, 409–413 (1987).
[Crossref]

Margulies, S.

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

Marota, J. J. A.

D. A. Boas, T. Gaudette, G. Strangman, X. Cheng, J. J. A. Marota, and J. B. Mandeville, “The Accuracy of Near Infrared Spectroscopy and Imaging during Focal Changes in Cerebral Hemodynamics,” NeuroImage 13, 76–90 (2001).
[Crossref] [PubMed]

Marsh, E. E.

H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
[Crossref] [PubMed]

Martinez-Concha, D.

R. Fernandez-Crehuet, C. Diaz-Molina, J. de Irala, D. Martinez-Concha, I. Salcedo-Leal, and J. Masa-Calles, “Nosocomial infection in an intensive-care unit: identification of risk factors.” Infect Control Hosp Epidemiol 18(12), 825–30 (1997).
[Crossref]

Masa-Calles, J.

R. Fernandez-Crehuet, C. Diaz-Molina, J. de Irala, D. Martinez-Concha, I. Salcedo-Leal, and J. Masa-Calles, “Nosocomial infection in an intensive-care unit: identification of risk factors.” Infect Control Hosp Epidemiol 18(12), 825–30 (1997).
[Crossref]

Mason, S.

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

Mathers, C. D.

A. D. Lopez, C. D. Mathers, M. Ezzati, D. T. Jamison, and C. J. L. Murray, “Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data,” The Lancet 367(9524), 1747–1757 (2006).
[Crossref]

McAlpine, C.

P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
[Crossref] [PubMed]

McCormick, D. C.

P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
[Crossref] [PubMed]

Meek, J. H.

A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
[Crossref] [PubMed]

Mehta, R.

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

Menon, C.

C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
[PubMed]

Migneco, O.

M. H. Mahagne, O. David, J. Darcourt, O. Migneco, A. Dunac, M. Chatel, and J. C. Baron, “Voxel-based mapping of cortical ischemic damage using Tc 99m L,L-ethyl cysteinate dimer SPECT in acute stroke,” J Neuroimaging 14(1), 23–32 (2004).
[PubMed]

Miyai, I.

I. Miyai, H. Yagura, M. Hatakenaka, I. Oda, I. Konishi, and K. Kubota, “Longitudinal Optical Imaging Study for Locomotor Recovery After Stroke,” Stroke 34(12), 2866–2870 (2003).
[Crossref] [PubMed]

Mohler, E. R.

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
[Crossref]

Moller, M.

A. Liebert, H. Wabnitz, J. Steinbrink, M. Moller, R. Macdonald, H. Rinneberg, A. Villringer, and H. Obrig, “Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance,” Neuroimage 24, 426–35 (2005).
[Crossref] [PubMed]

Montenegro, L.

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

Montenegro, L. M.

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

Morgenstern, L. B.

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Moss, H.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Mukai, S.

L. A. Lipsitz, S. Mukai, J. Hamner, M. Gagnon, and V. Babikian, “Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension,” Stroke 31(8), 1897–1903 (2000).
[Crossref] [PubMed]

Murray, C. J. L.

A. D. Lopez, C. D. Mathers, M. Ezzati, D. T. Jamison, and C. J. L. Murray, “Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data,” The Lancet 367(9524), 1747–1757 (2006).
[Crossref]

Murray, G.

P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
[Crossref] [PubMed]

Nagy, Z.

P. Bönöczk, G. Panczel, and Z. Nagy, “Vinpocetine increases cerebral blood flow and oxygenation in stroke patients: a near infrared spectroscopy and transcranial Doppler study,” European Journal of Ultrasound 15(1–2), 85–91 (2002).
[Crossref] [PubMed]

Nariai, T.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
[Crossref]

Nemoto, E. M.

R. R. Pindzola, J. R. Balzer, E. M. Nemoto, S. Goldstein, and H. Yonas, “Cerebrovascular reserve in patients with carotid occlusive disease assessed by stable xenon-enhanced ct cerebral blood flow and transcranial Doppler,” Stroke 32(8), 1811–1817 (2001).
[Crossref] [PubMed]

Nicholson, S. C.

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

Nicolson, S.

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

Nioka, S.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

Nolte, C.

M. Kohl, C. Nolte, H. R. Heekeren, S. Horst, U. Scholz, H. Obrig, and A. Villringer, “Determination of the wavelength dependence of the differential pathlength factor from near-infrared pulse signals,” Phys Med Biol 43(6), 1771–82 (1998).
[Crossref] [PubMed]

Obrig, H.

A. Liebert, H. Wabnitz, J. Steinbrink, M. Moller, R. Macdonald, H. Rinneberg, A. Villringer, and H. Obrig, “Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance,” Neuroimage 24, 426–35 (2005).
[Crossref] [PubMed]

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F. Vernieri, N. Rosato, F. Pauri, F. Tibuzzi, F. Passarelli, and P. M. Rossini, “Near Infrared Spectroscopy and Transcranial Doppler in Monohemispheric Stroke,” Eur Neurol 41(3), 159–162 (1999).
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S. L. Dawson, R. B. Panerai, and J. F. Potter, “Serial changes in static and dynamic cerebral autoregulation after acute ischaemic stroke,” Cerebrovasc Dis 16(1), 69–75 (2003).
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G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
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Quon, H.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
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J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Ralston, J.

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

Reithmeier, T.

C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
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P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
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E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
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A. Liebert, H. Wabnitz, J. Steinbrink, M. Moller, R. Macdonald, H. Rinneberg, A. Villringer, and H. Obrig, “Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance,” Neuroimage 24, 426–35 (2005).
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J. Steinbrink, H. Wabnitz, H. Obrig, A. Villringer, and H. Rinneberg, “Determining changes in NIR absorption using a layered model of the human head,” Phys Med Biol 46(3), 879–96. (2001).
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P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
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J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
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J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Rossini, P. M.

F. Vernieri, N. Rosato, F. Pauri, F. Tibuzzi, F. Passarelli, and P. M. Rossini, “Near Infrared Spectroscopy and Transcranial Doppler in Monohemispheric Stroke,” Eur Neurol 41(3), 159–162 (1999).
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C. C. Bishop, S. Powell, D. Rutt, and N. L. Browse, “Transcranial Doppler measurement of middle cerebral artery blood flow velocity: a validation study,” Stroke 17, 913–915 (1986).
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K. Sakatani, Y. Xie, W. Lichty, S. Li, and H. Zuo, “Language-Activated Cerebral Blood Oxygenation and Hemodynamic Changes of the Left Prefrontal Cortex in Poststroke Aphasic Patients : A Near-Infrared Spectroscopy Study,” Stroke 29(7), 1299–1304 (1998).
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G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
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E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
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M. Kohl, C. Nolte, H. R. Heekeren, S. Horst, U. Scholz, H. Obrig, and A. Villringer, “Determination of the wavelength dependence of the differential pathlength factor from near-infrared pulse signals,” Phys Med Biol 43(6), 1771–82 (1998).
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S. Schwarz, D. Georgiadis, A. Aschoff, and S. Schwab, “Effects of body position on intracranial pressure and cerebral perfusion in patients with large hemispheric stroke,” Stroke 33(2), 497–501 (2002).
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E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
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J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

Seghal, C. M.

G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
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E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

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C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
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T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

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E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

Siesjo, B. K.

J. Astrup, B. K. Siesjo, and L. Symon, “Thresholds in cerebral ischemia - the ischemic penumbra,” Stroke 12(6), 723–725 (1981).
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T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

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C. Terborg, S. Bramer, S. Harscher, M. Simon, and O. W. Witte, “Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green,” J Neurol Neurosurg Psychiatry 75(1), 38–42 (2004).
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J. Li, G. Dietsche, D. Iftime, S. E. Skipetrov, G. Maret, T. Elbert, B. Rockstroh, and T. Gisler, “Noninvasive detection of functional brain activity with near-infrared diffusing-wave spectroscopy,” J Biomed Opt 10(4), 044,002–1–044,002–12 (2005).
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Sobesky, J.

C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
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M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
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Steinbrink, J.

A. Liebert, H. Wabnitz, J. Steinbrink, M. Moller, R. Macdonald, H. Rinneberg, A. Villringer, and H. Obrig, “Bed-side assessment of cerebral perfusion in stroke patients based on optical monitoring of a dye bolus by time-resolved diffuse reflectance,” Neuroimage 24, 426–35 (2005).
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J. Steinbrink, H. Wabnitz, H. Obrig, A. Villringer, and H. Rinneberg, “Determining changes in NIR absorption using a layered model of the human head,” Phys Med Biol 46(3), 879–96. (2001).
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E. Keller, G. Wietasch, P. Ringleb, M. Scholz, S. Schwarz, R. Stingele, S. Schwab, D. Hanley, and W. Hacke, “Bedside monitoring of cerebral blood flow in patients with acute hemispheric stroke,” Crit Care Med 28(2), 511–516 (2000).
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P. Langhorne, D. J. Stott, L. Robertson, J. MacDonald, L. Jones, C. McAlpine, F. Dick, G. S. Taylor, and G. Murray, “Medical complications after stroke: a multicenter study,” Stroke 31(6), 1223–1229 (2000).
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U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
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Symon, L.

J. Astrup, B. K. Siesjo, and L. Symon, “Thresholds in cerebral ischemia - the ischemic penumbra,” Stroke 12(6), 723–725 (1981).
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H. Kato, M. Izumiyama, H. Koizumi, A. Takahashi, and Y. Itoyama, “Near-Infrared Spectroscopic Topography as a Tool to Monitor Motor Reorganization After Hemiparetic Stroke: A Comparison With Functional MRI,” Stroke 33(8), 2032–2036 (2002).
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C. Cheung, J. P. Culver, K. Takahashi, J. H. Greenberg, and A. G. Yodh, “In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies,” Phys. Med. and Biol. 46(8), 2053–2065 (2001).
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D. Hargroves, R. Tallis, V. Pomeroy, and A. Bhalla, “The influence of positioning upon cerebral oxygenation after acute stroke: a pilot study,” Age Ageing 37(5), 581–585 (2008).
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Tanfani, A.

A. Chieregato, A. Tanfani, C. Compagnone, R. Pascarella, L. Targa, and E. Fainardi, “Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure,” Neurosurgery 60(1), 115–123 (2007).
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Targa, L.

A. Chieregato, A. Tanfani, C. Compagnone, R. Pascarella, L. Targa, and E. Fainardi, “Cerebral blood flow in traumatic contusions is predominantly reduced after an induced acute elevation of cerebral perfusion pressure,” Neurosurgery 60(1), 115–123 (2007).
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T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
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C. Terborg, S. Bramer, S. Harscher, M. Simon, and O. W. Witte, “Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green,” J Neurol Neurosurg Psychiatry 75(1), 38–42 (2004).
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C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
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Wang, H. W.

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
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G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
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Wang, J.

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
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G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
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T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

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T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

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M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
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C. Terborg, S. Bramer, S. Harscher, M. Simon, and O. W. Witte, “Bedside assessment of cerebral perfusion reductions in patients with acute ischaemic stroke by near-infrared spectroscopy and indocyanine green,” J Neurol Neurosurg Psychiatry 75(1), 38–42 (2004).
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M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Woo, J.

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Woo, J. H.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

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D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys Med Biol 33, 1433–1442 (1988).
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P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
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K. Sakatani, Y. Xie, W. Lichty, S. Li, and H. Zuo, “Language-Activated Cerebral Blood Oxygenation and Hemodynamic Changes of the Left Prefrontal Cortex in Poststroke Aphasic Patients : A Near-Infrared Spectroscopy Study,” Stroke 29(7), 1299–1304 (1998).
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I. Miyai, H. Yagura, M. Hatakenaka, I. Oda, I. Konishi, and K. Kubota, “Longitudinal Optical Imaging Study for Locomotor Recovery After Stroke,” Stroke 34(12), 2866–2870 (2003).
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Yodh, A. G.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
[Crossref]

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
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T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
[Crossref] [PubMed]

G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
[Crossref] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
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C. Menon, G. M. Polin, I. Prabakaran, A. Hs, C. Cheung, J. P. Culver, J. Pingpank, C. S. Sehgal, A. G. Yodh, D. G. Buerk, and D. L. Fraker, “An Integrated Approach to Measuring Tumor Oxygen Status using Human Melanoma Xenografts as a Model,” Cancer Res. 63, 7232–40 (2003).
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J. P. Culver, T. Durduran, D. Furuya, C. Cheung, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Tomography of Cerebral Blood Flow, Oxygenation and Metabolism in Rat During Focal Ischemia,” J. Cereb. Blood Flow Metab. 23, 911–24 (2003).
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C. Cheung, J. P. Culver, K. Takahashi, J. H. Greenberg, and A. G. Yodh, “In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies,” Phys. Med. and Biol. 46(8), 2053–2065 (2001).
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D. A. Boas and A. G. Yodh, “Spatially varying dynamical properties of turbid media probed with diffusing temporal light correlation,” J. Opt. Soc. Am. A 14(1), 192–215 (1997).
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D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and Imaging with Diffusing Temporal Field Correlations,” Phys Rev Lett 75(9), 1855–1858 (1995).
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C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

Yonas, H.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
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R. R. Pindzola, J. R. Balzer, E. M. Nemoto, S. Goldstein, and H. Yonas, “Cerebrovascular reserve in patients with carotid occlusive disease assessed by stable xenon-enhanced ct cerebral blood flow and transcranial Doppler,” Stroke 32(8), 1811–1817 (2001).
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Yu, G.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
[Crossref]

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
[Crossref]

T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
[Crossref] [PubMed]

G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
[Crossref] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
[Crossref] [PubMed]

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

Yu, G. Y.

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

Zaharchuk, G.

M. Wintermark, M. Sesay, E. Barbier, K. Borbely, W. P. Dillon, J. D. Eastwood, T. C. Glenn, C. B. Grandin, S. Pedraza, J. F. Soustiel, T. Nariai, G. Zaharchuk, J. M. Caille, V. Dousset, and H. Yonas, “Comparative overview of brain perfusion imaging techniques,” Stroke 36(9), 83–99 (2005).
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P. van der Zee, M. Cope, S. R. Arridge, M. Essenpreis, L. A. Potter, A. D. Edwards, J. S. Wyatt, D. C. McCormick, S. C. Toth, E. O. R. Reynolds, and D. T. Delpy, “Experimentally measured optical pathlengths for the adult’s head, calf and forearm and the head of the newborn infant asa function of interoptode spacing,” Adv. Exp. Med. Biol. 316, 143–153 (1992).
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D. T. Delpy, M. Cope, P. van der Zee, S. Arridge, S. Wray, and J. Wyatt, “Estimation of optical pathlength through tissue from direct time of flight measurement,” Phys Med Biol 33, 1433–1442 (1988).
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Zhang, J.

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

Zhou, C.

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
[Crossref]

G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
[Crossref]

U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
[Crossref]

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

G. Yu, T. Durduran, G. Lech, C. Zhou, B. Chance, E. R. Mohler, and A. G. Yodh, “Time-dependent Blood Flow and Oxygenation in Human Skeletal Muscle Measured with Noninvasive Near-infrared Diffuse Optical Spectroscopies,” J Biomed Opt 10(3), 024,027–1–12 (2005).
[Crossref]

T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
[Crossref] [PubMed]

G. Yu, T. Durduran, C. Zhou, H. W. Wang, M. E. Putt, M. Saunders, C. M. Seghal, E. Glatstein, A. G. Yodh, and T. M. Busch, “Noninvasive Monitoring of Murine Tumor Blood Flow During and After Photodynamic Therapy Provides Early Assessment of Therapeutic Efficacy,” Clin. Cancer Res. 11, 3543–3552 (2005).
[Crossref] [PubMed]

T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
[Crossref] [PubMed]

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

Zhu, T. C.

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
[Crossref] [PubMed]

Zimmerman, R. A.

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

Zoppo, G. del

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

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K. Sakatani, Y. Xie, W. Lichty, S. Li, and H. Zuo, “Language-Activated Cerebral Blood Oxygenation and Hemodynamic Changes of the Left Prefrontal Cortex in Poststroke Aphasic Patients : A Near-Infrared Spectroscopy Study,” Stroke 29(7), 1299–1304 (1998).
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U. Sunar, H. Quon, T. Durduran, J. Zhang, J. Du, C. Zhou, G. Yu, R. Choe, A. Kilger, R. Lustig, L. Loevner, S. Nioka, B. Chance, and A. G. Yodh, “Non-invasive diffuse optical measurement of blood flow and blood oxygenation for monitoring radiation therapy in patients with head and neck tumors: a pilot study,” J Biomed Opt 11, 064,021 (2006).
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C. Zhou, R. Choe, N. Shah, T. Durduran, G. Yu, A. Durkin, D. Hsiang, R. Mehta, J. Butler, A. Cerussi, B. J. Tromberg, and A. G. Yodh, “Diffuse optical monitoring of blood flow and oxygenation in human breast cancer during early stages of neoadjuvant chemotherapy,” J Biomed Opt 12(5), 051,903 (2007).
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G. Yu, T. Floyd, T. Durduran, C. Zhou, J. J. Wang, J. A. Detre, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for muscle blood flow with concurrent arterial-spin-labeling perfusion,” Opt Exp 15, 1064–75 (2007).
[Crossref]

Opt Lett (2)

T. Durduran, R. Choe, G. Yu, C. Zhou, J. C. Tchou, B. J. Czerniecki, and A. G. Yodh, “Diffuse Optical Measurement of Blood flow in Breast Tumors,” Opt Lett 30, 2915–17 (2005).
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T. Durduran, G. Yu, M. G. Burnett, J. A. Detre, J. H. Greenberg, J. Wang, C. Zhou, and A. G. Yodh, “Diffuse Optical Measurements of Blood Flow, Blood Oxygenation and Metabolism in Human Brain during Sensorimotor Cortex Activation,” Opt Lett 29, 1766–1768 (2004).
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Opt. Exp (1)

C. Zhou, G. Yu, D. Furuya, J. H. Greenberg, A. G. Yodh, and T. Durduran, “Diffuse Optical Correlation tomography of cerebral blood flow during cortical spreading depression in rat brain,” Opt. Exp 14, 1125–44 (2006).
[Crossref]

Opt. Express (1)

U. Sunar, S. Makonnen, C. Zhou, T. Durduran, G. Yu, H. W. Wang, W. M. Lee, and A. G. Yodh, “Hemodynamic responses to antivascular therapy and ionizing radiation assessed by diffuse optical spectroscopies,” Opt. Express 15(23), 15,507–15,516 (2007).
[Crossref]

Photochem Photobiol (1)

G. Yu, T. Durduran, C. Zhou, T. C. Zhu, J. C. Finlay, T. M. Busch, S. B. Malkowicz, S. M. Hahn, and A. G. Yodh, “Real-time In situ Monitoring of Human Prostate Photodynamic Therapy with Diffuse Light,” Photochem Photobiol 82, 1279–84 (2006).
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M. Kohl, C. Nolte, H. R. Heekeren, S. Horst, U. Scholz, H. Obrig, and A. Villringer, “Determination of the wavelength dependence of the differential pathlength factor from near-infrared pulse signals,” Phys Med Biol 43(6), 1771–82 (1998).
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D. A. Boas, L. E. Campbell, and A. G. Yodh, “Scattering and Imaging with Diffusing Temporal Field Correlations,” Phys Rev Lett 75(9), 1855–1858 (1995).
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Phys. Med. and Biol. (1)

C. Cheung, J. P. Culver, K. Takahashi, J. H. Greenberg, and A. G. Yodh, “In vivo cerebrovascular measurement combining diffuse near-infrared absorption and correlation spectroscopies,” Phys. Med. and Biol. 46(8), 2053–2065 (2001).
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A. Duncan, J. H. Meek, M. Clemence, C. E. Elwell, L. Tyszczuk, M. Cope, and D. T. Delpy, “Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy,” Phys. Med. Biol. 40(2), 295–304. (1995).
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D. J. Pine, D. A. Weitz, P. M. Chaikin, and Herbolzheimer, “Diffusing-wave spectroscopy,” Phys. Rev. Lett. 60, 1134–1137 (1988).
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K. Sakatani, Y. Xie, W. Lichty, S. Li, and H. Zuo, “Language-Activated Cerebral Blood Oxygenation and Hemodynamic Changes of the Left Prefrontal Cortex in Poststroke Aphasic Patients : A Near-Infrared Spectroscopy Study,” Stroke 29(7), 1299–1304 (1998).
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H. Kato, M. Izumiyama, H. Koizumi, A. Takahashi, and Y. Itoyama, “Near-Infrared Spectroscopic Topography as a Tool to Monitor Motor Reorganization After Hemiparetic Stroke: A Comparison With Functional MRI,” Stroke 33(8), 2032–2036 (2002).
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I. Miyai, H. Yagura, M. Hatakenaka, I. Oda, I. Konishi, and K. Kubota, “Longitudinal Optical Imaging Study for Locomotor Recovery After Stroke,” Stroke 34(12), 2866–2870 (2003).
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J. A. Chalela, D. C. Alsop, J. B. Gonzalez-Atavales, J. A. Maldjian, S. E. Kasner, and J. A. Detre, “Magnetic resonance perfusion imaging in acute ischemic stroke using continuous arterial spin labeling,” Stroke 31(3), 680–687 (2000).
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H. P. Adams, B. H. Bendixen, L. J. Kappelle, J. Biller, B. B. Love, D. L. Gordon, and E. E. Marsh, “Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment,” Stroke 24(1), 35–41 (1993).
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J. Kelly, A. Rudd, R. Lewis, and B. J. Hunt, “Venous thromboembolism after acute stroke,” Stroke 32(1), 262–267 (2001).
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C. Dohmen, B. Bosche, R. Graf, T. Reithmeier, R. I. Ernestus, G. Brinker, J. Sobesky, and W. D. Heiss, “Identification and clinical impact of impaired cerebrovascular autoregulation in patients with malignant middle cerebral artery infarction,” Stroke 38(1), 56–61 (2007).
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L. A. Lipsitz, S. Mukai, J. Hamner, M. Gagnon, and V. Babikian, “Dynamic regulation of middle cerebral artery blood flow velocity in aging and hypertension,” Stroke 31(8), 1897–1903 (2000).
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A. D. Lopez, C. D. Mathers, M. Ezzati, D. T. Jamison, and C. J. L. Murray, “Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data,” The Lancet 367(9524), 1747–1757 (2006).
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Other (16)

T. Durduran, “Non-Invasive Measurements of Tissue Hemodynamics with Hybrid Diffuse Optical Methods,” Ph.D. Dissertation, University of Pennsylvania (2004).

European Stroke Organization, “Recommendations for Stroke Management,” http://www.eso-stroke.org/recommendations.php?cid=9&sid=1 (Last Accessed: January 28, 2009).

Compiled by Scott Prahl, Online: http://omlc.ogi.edu/spectra/hemoglobin/summary.html.

E. M. Buckley, M. N. Kim, T. Durduran, G. Yu, R. Choe, C. Zhou, S. Shultz, C. M. Sehgal, D. J. Licht, P. H. Arger, H. H. Hurt, N. M. Cook, and A. G. Yodh, “Monitoring Hemodynamic Changes in Preterm Infants Using Optical Spectroscopies and Doppler Ultrasound,” in OSA Biomedicals Topicals, p. CN279 (St Petersburg, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, B. L. Edlow, H. Moss, C. Zhou, G. Yu, R. Choe, S. K. Frangos, E. Wilensky-Mahoney, A. Kofke, J. M. Levine, R. L. Wolf, J. Woo, S. E. Kasner, B. L. Cucchiara, M. E. Putt, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bedside Monitoring of Cerebral Hemodynamics for Stroke and Neurocritical Care Using Novel Diffuse Optical Probes,” in Annual Meeting of the American Neurological Association, p. Abstract 298 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, B. L. Edlow, G. Yu, R. Choe, B. L. Cucchiara, M. Putt, Q. Shah, S. E. Kasner, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “CBF During Changes in Head of Bed Position in Acute, Ischemic Stroke Monitored at the bed-side: hemispheric effect of infarct,” in BRAIN 07, International Society of Cerebral Blood Flow and Metabolism (Osaka, Japan, 2007).

T. Durduran, C. Zhou, G. Yu, B. Edlow, R. Choe, Q. Shah, S. E. Kasner, B. L. Cucchiara, A. G. Yodh, J. H. Greenberg, and J. A. Detre, “Bed-side Monitoring of Cerebral Blood Flow (CBF) in Acute Stroke Patients During Changes in Head of Bed Position,” in International Stroke Conference, vol. P37 (American Heart Association, 2007).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, B. L. Edlow, E. Mahoney-Wilensky, S. M. Grady, J. Levine, J. A. Detre, J. H. Greenberg, and A. G. Yodh, “Diffuse Optical Measurements of Cerebral Blood Flow and Oxygenation in Patients after Traumatic Brain Injury or Subarachnoid Hemhorrage,” in OSA Biomedicals Topicals, p. CN237 (St Petersburg, FL, 2008).

M. N. Kim, T. Durduran, S. Frangos, E. M. Buckley, C. Zhou, G. Yu, H. Moss, B. L. Edlow, E. Maloney-Wilensky, J. A. Detre, J. H. Greenberg, W. A. Kofke, A. G. Yodh, M. S. Grady, J. H. Woo, R. L. Wolf, and J. Levine, “Validation Of Diffuse Correlation Spectroscopy Against Xenon CTCBF In Humans After Traumatic Brain Injury or Subarachnoid Hemorrhage,” in Neurocritical Care Society Annual Meeting (Miami, FL, 2008).

T. Durduran, M. N. Kim, E. M. Buckley, C. Zhou, G. Yu, R. Choe, J. H. Greenberg, J. A. Detre, and A. G. Yodh, “Diffuse Optical Monitoring of Cerebral Oxygen Metabolism at the Bed-Side in Cerebrovascular Disorders,” in OSA: Annual Meeting, Frontiers in Optics 2008 (Rochester, NY, 2008).

C. Zhou, S. Eucker, T. Durduran, G. Yu, J. Ralston, S. Friess, R. Ichor, S. Margulies, and A. G. Yodh, “Diffuse Optical Monitoring of Hemodynamic Changes in Piglet Brain with Closed Head Injury,” Journal of Neurotrauma submitted (2009).

T. Durduran, M. N. Kim, E. M. Buckley, R. Choe, C. Zhou, G. Y. Yu, and A. G. Yodh, “Validation of diffuse correlation spectroscopy for measurement of cerebral blood flow across spatial scales and against multiple modalities,” in SPIE Photonics West (San Jose, CA, 2009).

T. Durduran, C. Zhou, M. N. Kim, E. M. Buckley, G. Yu, R. Choe, S. M. Durning, S. Mason, L. M. Montenegro, S. C. Nicholson, R. A. Zimmerman, J. J. Wang, J. A. Detre, A. G. Yodh, and D. J. Licht, “Validation of Diffuse Correlation Spectroscopy for Non-Invasive, Continuous Monitoring of CBF in Neonates with Congenital Heart Defects,” in Annual Meeting of the American Neurological Association, p. Abstract 299 (American Neurological Association, Salt Lake City, Utah, 2008).

T. Durduran, C. Zhou, G. Yu, R. Choe, D. Silvestre, J. J. Wang, S. Nicolson, L. Montenegro, J. A. Detre, A. G. Yodh, and D. Licht, “Preoperative measurement of CO2 reactivity and cerebral autoregulation in neonates with severe congenital heart defects,” in SPIE Photonics West (San Jose, CA, 2007).

J. Adams, Harold P, G. del Zoppo, M. J. Alberts, D. L. Bhatt, L. Brass, A. Furlan, R. L. Grubb, R. T. Higashida, E. C. Jauch, C. Kidwell, P. D. Lyden, L. B. Morgenstern, A. I. Qureshi, R. H. Rosenwasser, P. A. Scott, and E. F. Wijdicks, “Guidelines for the Early Management of Adults With Ischemic Stroke,”.

J. C. Pinheiro and D. M. Bates, Mixed-effects models in S and S-Plus (Springer, New York, 2000).
[Crossref]

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Figures (4)

Fig. 1.
Fig. 1.

Illustration of the measurement protocol (top), the probe positioning (middle), and the corresponding volume interrogated by the diffusing photons . (Bottom) Sample intensity auto-correlation data measured at HOB = 30° and -5°.

Fig. 2.
Fig. 2.

Variation in CBF due to HOB positioning on first study day from peri- and contra-infarct hemispheres are shown for all patients (different color per patient)

Fig. 3.
Fig. 3.

(a) rCBF30° and (b) ∆THC30° as a function of time with HOB angle from a patient with right MCA occlusion. HOB position is a significant factor in both hemispheres, but a larger effect is observed in the infarct (right) hemisphere. Blue(gray) indicate left(right) hemispheres.

Fig. 4.
Fig. 4.

rCBF30° (a) and ∆THC30° (b) changes over time with HOB angle in a subject with vascular risk factors. Blue(gray) lines indicate left(right) hemispheres. Thick vertical bars indicate HOB changes to the labeled angle.

Tables (2)

Tables Icon

Table 1. Detailed patient characteristics (see Section 2.1 for details).

Tables Icon

Table 2. Statistical findings in acute ischemic stroke (AIS) group. SEM=Standard Error of Mean. Bold font implies statistical significance .

Equations (4)

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Δ A ( t , λ ) = ln I ( t , λ ) I 0 ( < t 30 ° > , λ ) = Δ μ a ( t , λ ) DPF ( λ ) r .
[ Δ μ a ( λ 1 , t ) Δ μ a ( λ 2 , t ) ] = [ H b ( λ 1 , t ) H b O 2 ( λ 1 , t ) H b ( λ 2 , t ) H b O 2 ( λ 2 , t ) ] [ Δ H b ( t ) Δ H b O 2 ( t ) ] .
G 1 ( r , t , τ ) = 3 μ s 4 π ( e K ( t , τ ) r r e K ( t , τ ) r 2 r 2 ) ,
g 2 ( r , t , τ ) = 1 + β g 1 ( r , t , τ ) 2 .

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