Abstract

Ultrasound-modulated optical imaging (or tomography) is an emerging biodiagnostic technique which provides the optical spectroscopic signature and the localization of an absorbing object embedded in a strongly scattering medium. We propose to improve the sensitivity of the technique by using a pulsed single-frequency laser to raise the optical peak power applied to the scattering medium and thereby collect more ultrasonically tagged photons. Moreover, when the detection of tagged photons is done with a photorefractive interferometer, the high optical peak power reduces the response time of the photorefractive crystal below the speckle field decorrelation time. Results obtained with a GaAs photorefractive interferometer are presented for 30- and 60-mm thick scattering media.

© 2008 Optical Society of America

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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]
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    [CrossRef]

2007 (2)

F. A. Duck, "Medical and non-medical protection standards for ultrasound and infrasound," Prog. Biophys. Mol. Biol. 93, 176-191 (2007).
[CrossRef]

S.-R. Kothapalli, S. Sakadzic, C. Kim, and L. V. Wang, "Imaging optically scattering objects with ultrasound-modulated optical tomography, " Opt. Lett. 32, 2351-2353 (2007).
[CrossRef]

2005 (1)

2004 (3)

2001 (1)

L. V. Wang, "Mechanisms of Ultrasonic Modulation of Multiply Scattered Coherent Light: An Analytic Model," Phys. Rev. Lett. 87, 043903 (2001).
[CrossRef]

1999 (1)

1995 (1)

1994 (1)

A. Blouin and J.-P. Monchalin, "Detection of ultrasonic motion of a scattering surface by two-wave mixing in a photorefractive GaAs crystal," Appl. Phys. Lett. 65, 932-934 (1994).
[CrossRef]

1992 (1)

D. Royer, N. Dubois, and M. Fink, "Optical probing of pulsed, focused ultrasonic fields using a heterodyne interferometer," Appl. Phys. Lett. 61, 153-155 (1992)
[CrossRef]

1986 (1)

J.-P. Monchalin, "Optical detection of ultrasound," IEEE Trans. Ultrason. Ferroelectr. Freq. Control 33, 485-499 (1986).
[CrossRef]

1985 (1)

J.-P. Monchalin, "Optical detection of ultrasound at a distance using a confocal Fabry-Perot interferometer," Appl. Phys. Lett. 47, 14-16 (1985).
[CrossRef]

1973 (1)

1967 (1)

W. A. Riley and W. R. Klein, "Piezo-optic coefficients of liquids," J. Acous. Soc. Am. 42, 1258-1261 (1967).
[CrossRef]

Atlan, M.

Blonigen, F.

Blouin, A.

A. Blouin and J.-P. Monchalin, "Detection of ultrasonic motion of a scattering surface by two-wave mixing in a photorefractive GaAs crystal," Appl. Phys. Lett. 65, 932-934 (1994).
[CrossRef]

Boccara, A. C.

Delaye, P.

DiMarzio, Ch. A.

Dubois, N.

D. Royer, N. Dubois, and M. Fink, "Optical probing of pulsed, focused ultrasonic fields using a heterodyne interferometer," Appl. Phys. Lett. 61, 153-155 (1992)
[CrossRef]

Duck, F. A.

F. A. Duck, "Medical and non-medical protection standards for ultrasound and infrasound," Prog. Biophys. Mol. Biol. 93, 176-191 (2007).
[CrossRef]

Fink, M.

D. Royer, N. Dubois, and M. Fink, "Optical probing of pulsed, focused ultrasonic fields using a heterodyne interferometer," Appl. Phys. Lett. 61, 153-155 (1992)
[CrossRef]

Forget, B. C.

Gross, M.

Hale, G. M.

Jacques, S. L.

Kim, C.

Klein, W. R.

W. A. Riley and W. R. Klein, "Piezo-optic coefficients of liquids," J. Acous. Soc. Am. 42, 1258-1261 (1967).
[CrossRef]

Kothapalli, S.-R.

Lebec, M.

Lévêque, S.

Maguluri, G.

Monchalin, J.-P.

A. Blouin and J.-P. Monchalin, "Detection of ultrasonic motion of a scattering surface by two-wave mixing in a photorefractive GaAs crystal," Appl. Phys. Lett. 65, 932-934 (1994).
[CrossRef]

J.-P. Monchalin, "Optical detection of ultrasound," IEEE Trans. Ultrason. Ferroelectr. Freq. Control 33, 485-499 (1986).
[CrossRef]

J.-P. Monchalin, "Optical detection of ultrasound at a distance using a confocal Fabry-Perot interferometer," Appl. Phys. Lett. 47, 14-16 (1985).
[CrossRef]

Murray, T. W.

Nieva, A.

Querry, M. R.

Ramaz, F.

Riley, W. A.

W. A. Riley and W. R. Klein, "Piezo-optic coefficients of liquids," J. Acous. Soc. Am. 42, 1258-1261 (1967).
[CrossRef]

Roosen, G.

Roy, R. A.

Royer, D.

D. Royer, N. Dubois, and M. Fink, "Optical probing of pulsed, focused ultrasonic fields using a heterodyne interferometer," Appl. Phys. Lett. 61, 153-155 (1992)
[CrossRef]

Saint-Jalmes, H.

Sakadzic, S.

Sui, L.

Wang, L.

Wang, L. V.

Zhao, X.

Appl. Opt. (1)

Appl. Phys. Lett. (3)

D. Royer, N. Dubois, and M. Fink, "Optical probing of pulsed, focused ultrasonic fields using a heterodyne interferometer," Appl. Phys. Lett. 61, 153-155 (1992)
[CrossRef]

J.-P. Monchalin, "Optical detection of ultrasound at a distance using a confocal Fabry-Perot interferometer," Appl. Phys. Lett. 47, 14-16 (1985).
[CrossRef]

A. Blouin and J.-P. Monchalin, "Detection of ultrasonic motion of a scattering surface by two-wave mixing in a photorefractive GaAs crystal," Appl. Phys. Lett. 65, 932-934 (1994).
[CrossRef]

IEEE Trans. Ultrason. Ferroelectr. Freq. Control (1)

J.-P. Monchalin, "Optical detection of ultrasound," IEEE Trans. Ultrason. Ferroelectr. Freq. Control 33, 485-499 (1986).
[CrossRef]

J. Acous. Soc. Am. (1)

W. A. Riley and W. R. Klein, "Piezo-optic coefficients of liquids," J. Acous. Soc. Am. 42, 1258-1261 (1967).
[CrossRef]

Opt. Express (1)

Opt. Lett. (6)

Phys. Rev. Lett. (1)

L. V. Wang, "Mechanisms of Ultrasonic Modulation of Multiply Scattered Coherent Light: An Analytic Model," Phys. Rev. Lett. 87, 043903 (2001).
[CrossRef]

Prog. Biophys. Mol. Biol. (1)

F. A. Duck, "Medical and non-medical protection standards for ultrasound and infrasound," Prog. Biophys. Mol. Biol. 93, 176-191 (2007).
[CrossRef]

Other (5)

Laser Institute of America, American National Standard for the Safe Use of Lasers ANSI Z136.1-2000 (ANSI, Orlando, Florida, 2000).

L. V. Wang and H. Wu, Biomedical Optics: Principles and Imaging (John Wiley and Sons, Hoboken, New Jersey, 2007).

S. Prahl, "Optical absorption of water," http://omlc.ogi.edu/spectra/water/.

L. E. Kinsler and A. R. Frey, Fundamentals of Acoustics (John Wiley and Sons, New York, 1962).

J. Krautkrämer and H. Krautkrämer, Ultrasonic Testing of Materials (Springer-Verlag, New York, 1977).

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