Abstract

A two-axis scanning catheter was developed for 3D endoscopic imaging with spectral domain optical coherence tomography (SD-OCT). The catheter incorporates a micro-mirror scanner implemented with microelectromechanical systems (MEMS) technology: the micro-mirror is mounted on a two-axis gimbal comprised of folded flexure hinges and is actuated by magnetic field. The scanner can run either statically in both axes or at the resonant frequency (>=350Hz) for the fast axis. The assembled catheter has an outer diameter of 2.8 mm and a rigid part of 12 mm in length. Its scanning range is ±20° in optical angle in both axes with low voltages (1~3V), resulting in a scannable length of approximately 1 mm at the surface in both axes, even with the small catheter size. The catheter was incorporated with a multi-functional SD-OCT system for 3D endoscopic imaging. Both intensity and polarization-sensitive images could be acquired simultaneously at 18.5K axial scans/s. In vivo 3D images of human fingertips and oral cavity tissue are presented as a demonstration.

© 2007 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |
  • |
  • |

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
    [CrossRef] [PubMed]
  2. J. G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nat. Biotechnol. 21,1361-1367 (2003).
    [CrossRef] [PubMed]
  3. J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
    [CrossRef] [PubMed]
  4. E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
    [CrossRef] [PubMed]
  5. J. Welzel, "Optical coherence tomography in dermatology: a review," Skin Research and Technology 7, 1-9 (2001), <Go to ISI>://000166541600001.
    [CrossRef] [PubMed]
  6. B. H. Park, C. Saxer, S. M. Srinivas, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography," J. Biomed. Opt. 6,474-479 (2001).
    [CrossRef] [PubMed]
  7. M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
    [CrossRef] [PubMed]
  8. M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
    [CrossRef] [PubMed]
  9. G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
    [CrossRef] [PubMed]
  10. Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
    [CrossRef]
  11. M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
    [CrossRef] [PubMed]
  12. S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
    [CrossRef] [PubMed]
  13. J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
    [CrossRef] [PubMed]
  14. B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography," Gastrointest. Endosc. 51,467-474 (2000).
    [CrossRef] [PubMed]
  15. S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
    [CrossRef] [PubMed]
  16. X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
    [CrossRef]
  17. H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
    [CrossRef] [PubMed]
  18. O. A. Meissner, J. Rieber, B. G., M. Oswald, S. Reim, U. Siebert, T. Redel, M. Reiser, and U. Mueller-Lisse, "Intravascular optical coherence tomography: comparison with histopathology in atherosclerotic peripheral artery specimens," J. Vasc. Interv. Radiol. 17,343-349 (2006).
    [CrossRef] [PubMed]
  19. G. J. Tearney, I. K. Jang, and B. E. Bouma, "Optical coherence tomography for imaging the vulnerable plaque," J. Biomed. Opt. 11,021002 (2006).
    [CrossRef] [PubMed]
  20. F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. WarrenJr, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3,239-250 (1998).
    [CrossRef] [PubMed]
  21. A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
    [CrossRef] [PubMed]
  22. B. J. Wong, J. R. P., S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, "In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients," Laryngoscope 115,1904-1911 (2005).
    [CrossRef] [PubMed]
  23. A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
    [PubMed]
  24. E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
    [CrossRef] [PubMed]
  25. G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
    [CrossRef] [PubMed]
  26. B. E. Bouma and G. J. Tearney, "Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography," Opt. Lett. 24,531-533 (1999).
    [CrossRef]
  27. V. X. D. Yang, M. L. Gordon, S.-j. Tang, N. E. Marcon, G. Gardiner, B. Qi, S. Bisland, E. Seng-Yue, S. Lo, J. Pekar, B. C. Wilson, and I. A. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts," Opt. Express 11,2416-2424 (2003).
    [CrossRef] [PubMed]
  28. T. Mitsui, "Dynamic range of optical reflectometry with spectral interferometry," Japanese Journal of Applied Physics Part 1-Regular Papers Short Notes & Review Papers 38, 6133-6137 (1999), <Go to ISI>://000083622000084.
  29. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11,889-894 (2003).
    [CrossRef] [PubMed]
  30. J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
    [CrossRef] [PubMed]
  31. M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11,2183-2189 (2003).
    [CrossRef] [PubMed]
  32. N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
    [CrossRef] [PubMed]
  33. N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
    [CrossRef] [PubMed]
  34. S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11,2953-2963 (2003).
    [CrossRef] [PubMed]
  35. S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22,340-342 (1997).
    [CrossRef] [PubMed]
  36. M. A. Choma, K. Hsu, and J. A. Izatt, "Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source," J. Biomed. Opt. 10,044009 (2005).
    [CrossRef]
  37. R. Huber, M. Wojtkowski, and J. G. Fujimoto, "Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography," Opt. Express 14,3225-3237 (2006).
    [CrossRef] [PubMed]
  38. S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
    [CrossRef] [PubMed]
  39. P. H. Tran, D. S. Mukai, M. Brenner, and Z. Chen, "In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe," Opt. Lett. 29,1236-1238 (2004).
    [CrossRef] [PubMed]
  40. P. R. Herz, Y. Chen, A. D. Aguirre, K. Schneider, P. Hsiung, J. G. Fujimoto, K. Madden, J. Schmitt, J. Goodnow, and C. Peterson, "Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography," Opt. Lett. 29,2261-2263 (2004).
    [CrossRef] [PubMed]
  41. X. Liu, M. J. Cobb, Y. Chen, M. B. Kimmey, and X. Li, "Rapid-scanning forward-imaging miniature endoscope for real-time optical coherence tomography," Opt. Lett. 29,1763-1765 (2004).
    [CrossRef] [PubMed]
  42. Y. T. Pan, H. K. Xie, and G. K. Fedder, "Endoscopic optical coherence tomography based on a microelectromechanical mirror," Opt. Lett. 261966-1968 (2001).
    [CrossRef]
  43. A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
    [CrossRef]
  44. W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
    [CrossRef]
  45. W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
    [CrossRef]
  46. A. D. Aguirre, P. R. Hertz, Y. Chen, J. G. Fujimoto, W. Piyawattanametha, L. Fan, and M. C. Wu, "Two-axis MEMS scanning catheter for ultrahigh resolution three-dimensional and en face Imaging," Opt. Express 15,2445-2453 (2007).
    [CrossRef] [PubMed]
  47. J. T. W. Yeow, V. X. D. Yang, A. Chahwan, M. L. Gordon, B. Qi, I. A. Vitkin, B. C. Wilson, and A. A. Goldenberg, "Micromachined 2-D scanner for 3-D optical coherence tomography," Sens. Actuators A. 117,331-340 (2005).
    [CrossRef]
  48. J. M. Zara, and P. E. Patterson, "Polyimide amplified piezoelectric scanning mirror for spectral domain optical coherence tomography," Appl. Phys. Lett. 89,263901 (2006).
    [CrossRef]
  49. T. Mitsui, Y. Takahashi, and Y. Watanabe, "A 2-axis optical scanner driven nonresonantly by electromagnetic force for OCT imaging," J. Micromech. Microeng. 16,2482-2487 (2006).
    [CrossRef]
  50. B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
    [CrossRef] [PubMed]
  51. J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
    [PubMed]

2007

2006

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

J. M. Zara, and P. E. Patterson, "Polyimide amplified piezoelectric scanning mirror for spectral domain optical coherence tomography," Appl. Phys. Lett. 89,263901 (2006).
[CrossRef]

T. Mitsui, Y. Takahashi, and Y. Watanabe, "A 2-axis optical scanner driven nonresonantly by electromagnetic force for OCT imaging," J. Micromech. Microeng. 16,2482-2487 (2006).
[CrossRef]

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
[CrossRef]

O. A. Meissner, J. Rieber, B. G., M. Oswald, S. Reim, U. Siebert, T. Redel, M. Reiser, and U. Mueller-Lisse, "Intravascular optical coherence tomography: comparison with histopathology in atherosclerotic peripheral artery specimens," J. Vasc. Interv. Radiol. 17,343-349 (2006).
[CrossRef] [PubMed]

G. J. Tearney, I. K. Jang, and B. E. Bouma, "Optical coherence tomography for imaging the vulnerable plaque," J. Biomed. Opt. 11,021002 (2006).
[CrossRef] [PubMed]

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

R. Huber, M. Wojtkowski, and J. G. Fujimoto, "Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography," Opt. Express 14,3225-3237 (2006).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

2005

B. J. Wong, J. R. P., S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, "In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients," Laryngoscope 115,1904-1911 (2005).
[CrossRef] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

M. A. Choma, K. Hsu, and J. A. Izatt, "Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source," J. Biomed. Opt. 10,044009 (2005).
[CrossRef]

J. T. W. Yeow, V. X. D. Yang, A. Chahwan, M. L. Gordon, B. Qi, I. A. Vitkin, B. C. Wilson, and A. A. Goldenberg, "Micromachined 2-D scanner for 3-D optical coherence tomography," Sens. Actuators A. 117,331-340 (2005).
[CrossRef]

2004

A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
[CrossRef]

P. H. Tran, D. S. Mukai, M. Brenner, and Z. Chen, "In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe," Opt. Lett. 29,1236-1238 (2004).
[CrossRef] [PubMed]

P. R. Herz, Y. Chen, A. D. Aguirre, K. Schneider, P. Hsiung, J. G. Fujimoto, K. Madden, J. Schmitt, J. Goodnow, and C. Peterson, "Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography," Opt. Lett. 29,2261-2263 (2004).
[CrossRef] [PubMed]

X. Liu, M. J. Cobb, Y. Chen, M. B. Kimmey, and X. Li, "Rapid-scanning forward-imaging miniature endoscope for real-time optical coherence tomography," Opt. Lett. 29,1763-1765 (2004).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
[CrossRef] [PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
[CrossRef] [PubMed]

M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
[CrossRef] [PubMed]

2003

2002

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

2001

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

B. H. Park, C. Saxer, S. M. Srinivas, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography," J. Biomed. Opt. 6,474-479 (2001).
[CrossRef] [PubMed]

Y. T. Pan, H. K. Xie, and G. K. Fedder, "Endoscopic optical coherence tomography based on a microelectromechanical mirror," Opt. Lett. 261966-1968 (2001).
[CrossRef]

2000

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography," Gastrointest. Endosc. 51,467-474 (2000).
[CrossRef] [PubMed]

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

1999

1998

1997

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22,340-342 (1997).
[CrossRef] [PubMed]

1996

1995

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

1992

1991

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Aguirre, A. D.

Anderson, R. R.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

Aretz, H. T.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Arya, A. V.

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

Bisland, S.

Boppart, S. A.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
[CrossRef] [PubMed]

Bouma, B. E.

G. J. Tearney, I. K. Jang, and B. E. Bouma, "Optical coherence tomography for imaging the vulnerable plaque," J. Biomed. Opt. 11,021002 (2006).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
[CrossRef] [PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11,2953-2963 (2003).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography," Gastrointest. Endosc. 51,467-474 (2000).
[CrossRef] [PubMed]

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

B. E. Bouma and G. J. Tearney, "Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography," Opt. Lett. 24,531-533 (1999).
[CrossRef]

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
[CrossRef] [PubMed]

Brand, B.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Brand, S.

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

Brenner, M.

Brezinski, M. E.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
[CrossRef] [PubMed]

Burns, J. A.

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

Cense, B.

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
[CrossRef] [PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
[CrossRef] [PubMed]

M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
[CrossRef] [PubMed]

Chahwan, A.

J. T. W. Yeow, V. X. D. Yang, A. Chahwan, M. L. Gordon, B. Qi, I. A. Vitkin, B. C. Wilson, and A. A. Goldenberg, "Micromachined 2-D scanner for 3-D optical coherence tomography," Sens. Actuators A. 117,331-340 (2005).
[CrossRef]

Chak, A.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Chan, R. C.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

Chang, W.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Chen, T. C.

Chen, Y.

Chen, Z.

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

P. H. Tran, D. S. Mukai, M. Brenner, and Z. Chen, "In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe," Opt. Lett. 29,1236-1238 (2004).
[CrossRef] [PubMed]

Chinn, S. R.

Choma, M. A.

M. A. Choma, K. Hsu, and J. A. Izatt, "Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source," J. Biomed. Opt. 10,044009 (2005).
[CrossRef]

M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11,2183-2189 (2003).
[CrossRef] [PubMed]

Cobb, M. J.

Compton, C. C.

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography," Gastrointest. Endosc. 51,467-474 (2000).
[CrossRef] [PubMed]

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

de Boer, J. F.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
[CrossRef] [PubMed]

M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
[CrossRef] [PubMed]

M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11,2953-2963 (2003).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
[CrossRef] [PubMed]

B. H. Park, C. Saxer, S. M. Srinivas, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography," J. Biomed. Opt. 6,474-479 (2001).
[CrossRef] [PubMed]

Desjardins, A. E.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

Drexler, W.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

Evans, J. A.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

Fan, L.

Fedder, G. K.

A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
[CrossRef]

Y. T. Pan, H. K. Xie, and G. K. Fedder, "Endoscopic optical coherence tomography based on a microelectromechanical mirror," Opt. Lett. 261966-1968 (2001).
[CrossRef]

Feldchtein, F.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Feldchtein, F. I.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. WarrenJr, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3,239-250 (1998).
[CrossRef] [PubMed]

Fercher, A. F.

Flotte, T.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Freund, J.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Fritscher-Ravens, A.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Fujimoto, J. G.

A. D. Aguirre, P. R. Hertz, Y. Chen, J. G. Fujimoto, W. Piyawattanametha, L. Fan, and M. C. Wu, "Two-axis MEMS scanning catheter for ultrahigh resolution three-dimensional and en face Imaging," Opt. Express 15,2445-2453 (2007).
[CrossRef] [PubMed]

R. Huber, M. Wojtkowski, and J. G. Fujimoto, "Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography," Opt. Express 14,3225-3237 (2006).
[CrossRef] [PubMed]

P. R. Herz, Y. Chen, A. D. Aguirre, K. Schneider, P. Hsiung, J. G. Fujimoto, K. Madden, J. Schmitt, J. Goodnow, and C. Peterson, "Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography," Opt. Lett. 29,2261-2263 (2004).
[CrossRef] [PubMed]

J. G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nat. Biotechnol. 21,1361-1367 (2003).
[CrossRef] [PubMed]

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22,340-342 (1997).
[CrossRef] [PubMed]

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
[CrossRef] [PubMed]

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Gardiner, G.

Gelikonov, G.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Gelikonov, G. V.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. WarrenJr, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3,239-250 (1998).
[CrossRef] [PubMed]

Gelikonov, V.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Gelikonov, V. M.

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. WarrenJr, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3,239-250 (1998).
[CrossRef] [PubMed]

Gladkova, N.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Gladkova, N. D.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. WarrenJr, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3,239-250 (1998).
[CrossRef] [PubMed]

Goldenberg, A. A.

J. T. W. Yeow, V. X. D. Yang, A. Chahwan, M. L. Gordon, B. Qi, I. A. Vitkin, B. C. Wilson, and A. A. Goldenberg, "Micromachined 2-D scanner for 3-D optical coherence tomography," Sens. Actuators A. 117,331-340 (2005).
[CrossRef]

Goodnow, J.

Gordon, M. L.

Gregory, K.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Halpern, E. F.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Hee, M. R.

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Heng, X.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
[CrossRef]

Hertz, P. R.

Herz, P. R.

Hitzenberger, C. K.

Houser, S. L.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Hsiung, P.

Hsu, K.

M. A. Choma, K. Hsu, and J. A. Izatt, "Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source," J. Biomed. Opt. 10,044009 (2005).
[CrossRef]

Huang, D.

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Huber, R.

Iftimia, N.

Iksanov, R. R.

Isenberg, G. A.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Izatt, J. A.

M. A. Choma, K. Hsu, and J. A. Izatt, "Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source," J. Biomed. Opt. 10,044009 (2005).
[CrossRef]

M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11,2183-2189 (2003).
[CrossRef] [PubMed]

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Jackle, S.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Jain, A.

A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
[CrossRef]

Jang, I. K.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

G. J. Tearney, I. K. Jang, and B. E. Bouma, "Optical coherence tomography for imaging the vulnerable plaque," J. Biomed. Opt. 11,021002 (2006).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Jung, W.

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

Kamensky, V. A.

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

Kang, D. H.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Kauffman, C. R.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Kimmey, M. B.

Klein, A. M.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

Klein, M.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

Kobayashi, K.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Kobler, J. B.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

Kopa, A.

A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
[CrossRef]

Krinsky, M. L.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

Kuranov, R. V.

Leitgeb, R.

Li, X.

Li, X. D.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

Lin, C. P.

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Liu, X.

Lo, S.

Madden, K.

Marcon, N. E.

Mashimo, H.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

McCormick, D. T.

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

McDowell, E. J.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
[CrossRef]

Meissner, O. A.

O. A. Meissner, J. Rieber, B. G., M. Oswald, S. Reim, U. Siebert, T. Redel, M. Reiser, and U. Mueller-Lisse, "Intravascular optical coherence tomography: comparison with histopathology in atherosclerotic peripheral artery specimens," J. Vasc. Interv. Radiol. 17,343-349 (2006).
[CrossRef] [PubMed]

Mitsui, T.

T. Mitsui, Y. Takahashi, and Y. Watanabe, "A 2-axis optical scanner driven nonresonantly by electromagnetic force for OCT imaging," J. Micromech. Microeng. 16,2482-2487 (2006).
[CrossRef]

Morozov, A. N.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

Mujat, M.

Mukai, D. S.

Mutinga, M.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

Nassif, N.

Nassif, N. A.

Nishioka, N. S.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography," Gastrointest. Endosc. 51,467-474 (2000).
[CrossRef] [PubMed]

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

Oh, W. Y.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

Ourutina, M. N.

Pan, Y. T.

A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
[CrossRef]

Y. T. Pan, H. K. Xie, and G. K. Fedder, "Endoscopic optical coherence tomography based on a microelectromechanical mirror," Opt. Lett. 261966-1968 (2001).
[CrossRef]

Park, B. H.

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
[CrossRef] [PubMed]

M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
[CrossRef] [PubMed]

M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
[CrossRef] [PubMed]

B. H. Park, C. Saxer, S. M. Srinivas, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography," J. Biomed. Opt. 6,474-479 (2001).
[CrossRef] [PubMed]

Patterson, P. E.

J. M. Zara, and P. E. Patterson, "Polyimide amplified piezoelectric scanning mirror for spectral domain optical coherence tomography," Appl. Phys. Lett. 89,263901 (2006).
[CrossRef]

Pedut-Kloizman, T.

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

Pekar, J.

Peterson, C.

Pierce, M. C.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
[CrossRef] [PubMed]

M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
[CrossRef] [PubMed]

Pitris, C.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

Piyawattanametha, W.

Poneros, J. M.

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

Puliafito, C. A.

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Qi, B.

Reitze, D. H.

Rieber, J.

O. A. Meissner, J. Rieber, B. G., M. Oswald, S. Reim, U. Siebert, T. Redel, M. Reiser, and U. Mueller-Lisse, "Intravascular optical coherence tomography: comparison with histopathology in atherosclerotic peripheral artery specimens," J. Vasc. Interv. Radiol. 17,343-349 (2006).
[CrossRef] [PubMed]

Rollins, A. M.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Sarunic, M. V.

Saxer, C.

B. H. Park, C. Saxer, S. M. Srinivas, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography," J. Biomed. Opt. 6,474-479 (2001).
[CrossRef] [PubMed]

Schlendorf, K. H.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Schmitt, J.

Schneider, K.

Schroder, S.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Schuman, J. S.

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Segeev, A.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Seitz, U.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Seng-Yue, E.

Sergeev, A. M.

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. WarrenJr, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3,239-250 (1998).
[CrossRef] [PubMed]

Shakhov, A. V.

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

Sheridan, R. L.

M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
[CrossRef] [PubMed]

Shishkov, M.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Sivak, M. V. J.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Snopova, L. B.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

Soehendra, N.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Southern, J. F.

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
[CrossRef] [PubMed]

Srinivas, S. M.

B. H. Park, C. Saxer, S. M. Srinivas, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography," J. Biomed. Opt. 6,474-479 (2001).
[CrossRef] [PubMed]

Stinson, W. G.

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Strasswimmer, J.

M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
[CrossRef] [PubMed]

Streltsova, O. S.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

Suter, M. J.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

Swanson, E. A.

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22,340-342 (1997).
[CrossRef] [PubMed]

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
[CrossRef] [PubMed]

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

Takahashi, Y.

T. Mitsui, Y. Takahashi, and Y. Watanabe, "A 2-axis optical scanner driven nonresonantly by electromagnetic force for OCT imaging," J. Micromech. Microeng. 16,2482-2487 (2006).
[CrossRef]

Tang, S.-j.

Tearney, G. J.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

G. J. Tearney, I. K. Jang, and B. E. Bouma, "Optical coherence tomography for imaging the vulnerable plaque," J. Biomed. Opt. 11,021002 (2006).
[CrossRef] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11,2953-2963 (2003).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
[CrossRef] [PubMed]

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography," Gastrointest. Endosc. 51,467-474 (2000).
[CrossRef] [PubMed]

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

B. E. Bouma and G. J. Tearney, "Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography," Opt. Lett. 24,531-533 (1999).
[CrossRef]

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
[CrossRef] [PubMed]

Terentieva, A.

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

Terentjeva, A. B.

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

Tien, N. C.

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

Tran, P. H.

Unq-Runyawee, R.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Vakoc, B. J.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

Van Dam, J.

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

Vitkin, I. A.

Wang, L.

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

Warren, J. A.

Watanabe, Y.

T. Mitsui, Y. Takahashi, and Y. Watanabe, "A 2-axis optical scanner driven nonresonantly by electromagnetic force for OCT imaging," J. Micromech. Microeng. 16,2482-2487 (2006).
[CrossRef]

Weissman, N. M.

Wilder-Smith, P.

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

Willis, J.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Wilson, B. C.

Wojtkowski, M.

Wong, B. J.

B. J. Wong, J. R. P., S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, "In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients," Laryngoscope 115,1904-1911 (2005).
[CrossRef] [PubMed]

Wong, R. C.

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

Wu, J.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
[CrossRef]

Wu, M. C.

Xie, H. K.

A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
[CrossRef]

Y. T. Pan, H. K. Xie, and G. K. Fedder, "Endoscopic optical coherence tomography based on a microelectromechanical mirror," Opt. Lett. 261966-1968 (2001).
[CrossRef]

Yabushita, H.

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Yang, C.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
[CrossRef]

Yang, C. H.

Yang, V. X. D.

Yaqoob, Z.

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
[CrossRef]

Yeow, J. T. W.

J. T. W. Yeow, V. X. D. Yang, A. Chahwan, M. L. Gordon, B. Qi, I. A. Vitkin, B. C. Wilson, and A. A. Goldenberg, "Micromachined 2-D scanner for 3-D optical coherence tomography," Sens. Actuators A. 117,331-340 (2005).
[CrossRef]

Yun, S. H.

Zagaynova, E. V.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

Zara, J. M.

J. M. Zara, and P. E. Patterson, "Polyimide amplified piezoelectric scanning mirror for spectral domain optical coherence tomography," Appl. Phys. Lett. 89,263901 (2006).
[CrossRef]

Zeitels, S. M.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

Zhang, J.

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

Ann. Otol. Rhinol. Laryngol.

A. M. Klein, M. C. Pierce, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. Shishkov, and J. F. de Boer, "Imaging the human vocal folds in vivo with optical coherence tomography: a preliminary experience," Ann. Otol. Rhinol. Laryngol. 115,277-284 (2006).
[PubMed]

J. A. Burns, S. M. Zeitels, R. R. Anderson, J. B. Kobler, M. C. Pierce, and J. F. de Boer, "Imaging the mucosa of the human vocal fold with optical coherence tomography " Ann. Otol. Rhinol. Laryngol. 114,671-66 (2005).
[PubMed]

Appl. Phys. Lett.

J. M. Zara, and P. E. Patterson, "Polyimide amplified piezoelectric scanning mirror for spectral domain optical coherence tomography," Appl. Phys. Lett. 89,263901 (2006).
[CrossRef]

W. Jung, D. T. McCormick, J. Zhang, L. Wang, N. C. Tien, and Z. Chen, "Three-dimensional endoscopic optical coherence tomography by use of a two-axis microelectromechanical scanning mirror," Appl. Phys. Lett. 88,163901 (2006).
[CrossRef]

Burns

M. C. Pierce, R. L. Sheridan, B. H. Park, B. Cense, and J. F. de Boer, "Collagen denaturation can be quantified in burned human skin using polarization-sensitive optical coherence tomography " Burns 30,511-517 (2004).
[CrossRef] [PubMed]

Circulation

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. H. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, and G. J. Tearney, "Characterization of human atherosclerosis by optical coherence tomography," Circulation 106,1640-1645 (2002).
[CrossRef] [PubMed]

Current opinion in Ophthalmology

J. S. Schuman, M. R. Hee, A. V. Arya, T. Pedut-Kloizman, C. A. Puliafito, J. G. Fujimoto, and E. A. Swanson, "Optical coherence tomography: a new tool for glaucoma diagnosis," Current opinion in Ophthalmology 6,89-95 (1995).
[CrossRef] [PubMed]

Endoscopy

S. Brand, J. M. Poneros, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Optical coherence tomography in the gastrointestinal tract," Endoscopy 32,796-803 (2000).
[CrossRef] [PubMed]

S. Jackle, N. Gladkova, F. Feldchtein, A. Terentieva, B. Brand, G. Gelikonov, V. Gelikonov, A. Segeev, A. Fritscher-Ravens, J. Freund, U. Seitz, S. Schroder, and N. Soehendra, "In vivo endoscopic optical coherence tomography of esophagitis, Barrett's esophagus, and adenocarcinoma of the esophagus," Endoscopy 32,750-755 (2000).
[CrossRef] [PubMed]

X. D. Li, S. A. Boppart, J. Van Dam, H. Mashimo, M. Mutinga, W. Drexler, M. Klein, C. Pitris, M. L. Krinsky, M. E. Brezinski, and J. G. Fujimoto, "Optical coherence tomography: advanced technology for the endoscopic imaging of Barrett's esophagus," Endoscopy 32,921-930 (2000).
[CrossRef]

Gastroenterology

J. M. Poneros, S. Brand, B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "Diagnosis of specialized intestinal metaplasia by optical coherence tomography," Gastroenterology 120,7-12 (2001).
[CrossRef] [PubMed]

Gastrointest. Endosc.

B. E. Bouma, G. J. Tearney, C. C. Compton, and N. S. Nishioka, "High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography," Gastrointest. Endosc. 51,467-474 (2000).
[CrossRef] [PubMed]

M. V. J. Sivak, K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Unq-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, and J. Willis, "High-resolution endoscopic imaging of the GI tract using optical coherence tomography," Gastrointest. Endosc. 51,474-479 (2000).
[CrossRef] [PubMed]

IEEE J. Sel. Top. Quantum Electron.

A. Jain, A. Kopa, Y. T. Pan, G. K. Fedder, and H. K. Xie, "A two-axis electrothermal micromirror for endoscopic optical coherence tomography," IEEE J. Sel. Top. Quantum Electron. 10,636-642 (2004).
[CrossRef]

W. Jung, J. Zhang, L. Wang, P. Wilder-Smith, Z. Chen, D. T. McCormick, and N. C. Tien, "Three-dimensional optical coherence tomography employing a 2-axis microelectromechanical scanning mirror," IEEE J. Sel. Top. Quantum Electron. 11,806-810 (2005).
[CrossRef]

J. Biomed. Opt.

G. J. Tearney, I. K. Jang, and B. E. Bouma, "Optical coherence tomography for imaging the vulnerable plaque," J. Biomed. Opt. 11,021002 (2006).
[CrossRef] [PubMed]

B. H. Park, C. Saxer, S. M. Srinivas, and J. F. de Boer, "In vivo burn depth determination by high-speed fiber-based polarization sensitive optical coherence tomography," J. Biomed. Opt. 6,474-479 (2001).
[CrossRef] [PubMed]

Z. Yaqoob, J. Wu, E. J. McDowell, X. Heng, and C. Yang, "Methods and application areas of endoscopic optical coherence tomography," J. Biomed. Opt. 11,063001 (2006).
[CrossRef]

M. A. Choma, K. Hsu, and J. A. Izatt, "Swept source optical coherence tomography using an all-fiber 1300-nm ring laser source," J. Biomed. Opt. 10,044009 (2005).
[CrossRef]

J. Invest. Dermatol.

M. C. Pierce, J. Strasswimmer, B. H. Park, B. Cense, and J. F. de Boer, "Advances in optical coherence tomography imaging for dermatology " J. Invest. Dermatol. 123,458-463 (2004).
[CrossRef] [PubMed]

J. Micromech. Microeng.

T. Mitsui, Y. Takahashi, and Y. Watanabe, "A 2-axis optical scanner driven nonresonantly by electromagnetic force for OCT imaging," J. Micromech. Microeng. 16,2482-2487 (2006).
[CrossRef]

J. Surg. Oncol.

A. V. Shakhov, A. B. Terentjeva, V. A. Kamensky, L. B. Snopova, V. M. Gelikonov, F. I. Feldchtein, and A. M. Sergeev, "Optical coherence tomography monitoring for laser surgery of laryngeal carcinoma," J. Surg. Oncol. 77,253-258 (2001).
[CrossRef] [PubMed]

J. Urol.

E. V. Zagaynova, O. S. Streltsova, N. D. Gladkova, L. B. Snopova, G. V. Gelikonov, F. I. Feldchtein, and A. N. Morozov, "In vivo optical coherence tomography feasibility for bladder disease," J. Urol. 167,1492-1496 (2002).
[CrossRef] [PubMed]

J. Vasc. Interv. Radiol.

O. A. Meissner, J. Rieber, B. G., M. Oswald, S. Reim, U. Siebert, T. Redel, M. Reiser, and U. Mueller-Lisse, "Intravascular optical coherence tomography: comparison with histopathology in atherosclerotic peripheral artery specimens," J. Vasc. Interv. Radiol. 17,343-349 (2006).
[CrossRef] [PubMed]

Laryngoscope

B. J. Wong, J. R. P., S. Guo, J. M. Ridgway, U. Mahmood, J. Su, T. Y. Shibuya, R. L. Crumley, M. Gu, W. B. Armstrong, and Z. Chen, "In vivo optical coherence tomography of the human larynx: normative and benign pathology in 82 patients," Laryngoscope 115,1904-1911 (2005).
[CrossRef] [PubMed]

Nat. Biotechnol.

J. G. Fujimoto, "Optical coherence tomography for ultrahigh resolution in vivo imaging," Nat. Biotechnol. 21,1361-1367 (2003).
[CrossRef] [PubMed]

Nat. Med.

S. H. Yun, G. J. Tearney, B. J. Vakoc, M. Shishkov, W. Y. Oh, A. E. Desjardins, M. J. Suter, R. C. Chan, J. A. Evans, I. K. Jang, N. S. Nishioka, J. F. de Boer, and B. E. Bouma, "Comprehensive volumetric optical microscopy in vivo," Nat. Med. 12,1429-1433 (2006).
[CrossRef] [PubMed]

Opt. Express

A. D. Aguirre, P. R. Hertz, Y. Chen, J. G. Fujimoto, W. Piyawattanametha, L. Fan, and M. C. Wu, "Two-axis MEMS scanning catheter for ultrahigh resolution three-dimensional and en face Imaging," Opt. Express 15,2445-2453 (2007).
[CrossRef] [PubMed]

B. H. Park, M. C. Pierce, B. Cense, S. H. Yun, M. Mujat, G. J. Tearney, B. E. Bouma, and J. F. de Boer, "Real-time fiber-based multi-functional spectral-domain optical coherence tomography at 1.3 um," Opt. Express 13,3931-3944 (2005).
[CrossRef] [PubMed]

F. I. Feldchtein, G. V. Gelikonov, V. M. Gelikonov, R. R. Iksanov, R. V. Kuranov, A. M. Sergeev, N. D. Gladkova, M. N. Ourutina, J. A. WarrenJr, and D. H. Reitze, "In vivo OCT imaging of hard and soft tissue of the oral cavity," Opt. Express 3,239-250 (1998).
[CrossRef] [PubMed]

V. X. D. Yang, M. L. Gordon, S.-j. Tang, N. E. Marcon, G. Gardiner, B. Qi, S. Bisland, E. Seng-Yue, S. Lo, J. Pekar, B. C. Wilson, and I. A. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography (Part III): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts," Opt. Express 11,2416-2424 (2003).
[CrossRef] [PubMed]

R. Huber, M. Wojtkowski, and J. G. Fujimoto, "Fourier Domain Mode Locking (FDML): A new laser operating regime and applications for optical coherence tomography," Opt. Express 14,3225-3237 (2006).
[CrossRef] [PubMed]

N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12,367-376 (2004).
[CrossRef] [PubMed]

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, "High-speed optical frequency-domain imaging," Opt. Express 11,2953-2963 (2003).
[CrossRef] [PubMed]

R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of fourier domain vs. time domain optical coherence tomography," Opt. Express 11,889-894 (2003).
[CrossRef] [PubMed]

M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11,2183-2189 (2003).
[CrossRef] [PubMed]

Opt. Lett.

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, "In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography," Opt. Lett. 29,480-482 (2004).
[CrossRef] [PubMed]

J. F. de Boer, B. Cense, B. H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, "Improved singla-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography," Opt. Lett. 28,2067-2069 (2003).
[CrossRef] [PubMed]

S. R. Chinn, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography using a frequency-tunable optical source," Opt. Lett. 22,340-342 (1997).
[CrossRef] [PubMed]

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. M. Weissman, J. F. Southern, and J. G. Fujimoto, "Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21,543-545 (1996).
[CrossRef] [PubMed]

B. E. Bouma and G. J. Tearney, "Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography," Opt. Lett. 24,531-533 (1999).
[CrossRef]

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, "High-speed optical coherence domain reflectometry," Opt. Lett. 17,151-153 (1992).
[CrossRef] [PubMed]

P. H. Tran, D. S. Mukai, M. Brenner, and Z. Chen, "In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe," Opt. Lett. 29,1236-1238 (2004).
[CrossRef] [PubMed]

P. R. Herz, Y. Chen, A. D. Aguirre, K. Schneider, P. Hsiung, J. G. Fujimoto, K. Madden, J. Schmitt, J. Goodnow, and C. Peterson, "Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography," Opt. Lett. 29,2261-2263 (2004).
[CrossRef] [PubMed]

X. Liu, M. J. Cobb, Y. Chen, M. B. Kimmey, and X. Li, "Rapid-scanning forward-imaging miniature endoscope for real-time optical coherence tomography," Opt. Lett. 29,1763-1765 (2004).
[CrossRef] [PubMed]

Y. T. Pan, H. K. Xie, and G. K. Fedder, "Endoscopic optical coherence tomography based on a microelectromechanical mirror," Opt. Lett. 261966-1968 (2001).
[CrossRef]

Science

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, "Optical coherence tomography," Science 254,1178-1181 (1991).
[CrossRef] [PubMed]

G. J. Tearney, M. E. Brezinski, B. E. Bouma, S. A. Boppart, C. Pitris, J. F. Southern, and J. G. Fujimoto, "In vivo endoscopic optical biopsy with optical coherence tomography," Science 276,2037-2039 (1997).
[CrossRef] [PubMed]

Sens. Actuators A.

J. T. W. Yeow, V. X. D. Yang, A. Chahwan, M. L. Gordon, B. Qi, I. A. Vitkin, B. C. Wilson, and A. A. Goldenberg, "Micromachined 2-D scanner for 3-D optical coherence tomography," Sens. Actuators A. 117,331-340 (2005).
[CrossRef]

Other

J. Welzel, "Optical coherence tomography in dermatology: a review," Skin Research and Technology 7, 1-9 (2001), <Go to ISI>://000166541600001.
[CrossRef] [PubMed]

T. Mitsui, "Dynamic range of optical reflectometry with spectral interferometry," Japanese Journal of Applied Physics Part 1-Regular Papers Short Notes & Review Papers 38, 6133-6137 (1999), <Go to ISI>://000083622000084.

Supplementary Material (1)

» Media 1: AVI (4889 KB)     

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (6)

Fig. 1.
Fig. 1.

The MEMS mirror scanner (a) and a SEM picture of a supporting folded flexure (b). A micro-mirror is supported by a 2-axis gimbal structure composed of folded flexure hinges and can deflect in two orthogonal axes: inner and outer axis depicted in the picture.

Fig. 2.
Fig. 2.

MEMS scanner fabrication process

Fig. 3.
Fig. 3.

Catheter schematic (a) and photograph (b). Light path is drawn in red in the schematic and light is redirected by the MEMS scanner. The catheter photograph was taken with a ruler underneath with millimeter unit. The optical fiber is glued to the catheter body with UV curing epoxy. The MEMS scanner appears in the photograph refracted by the plano-convex cylindrical window.

Fig. 4.
Fig. 4.

Scanning range of the MEMS scanner. The lines are linear fits of measurement points.

Fig. 5.
Fig. 5.

In vivo finger tip images: cross-sectional images in the inner axis (a) and outer axis (b) respectively, and 3D reconstructed images (c, d) based on the consecutive cross-sectional images in (a) and (b) respectively.

Fig. 6.
Fig. 6.

Movie of cross-sectional images of internal oral cavity in-vivo. Intensity image (a) and polarization sensitive (PS) image (b) are updated with the cross-section advancing in the orthogonal axis. The intensity image shows layered structures of epithelium and glands from superficial to deep, and the PS image shows no birefringence in the epithelium and some birefringence in the glands [Media 1]

Metrics