Abstract

We measure transmitted signals with time, aperture, and angle gating for comparison in micro-sphere suspension, chicken breast and chicken liver tissues. We find that in each sample, the small aperture-gated (angle-gated) signals for imaging are essentially different from those of early time gating. Meanwhile, the signals obtained from aperture and angle gating come from quite different parts of the transmitted photons. For biological tissues of different structures, different gating methods may lead to different levels of imaging quality. Also, the results indicate the generally different scattering characteristics of biological tissues from that of a particle-based phantom. The scattering nature in the biological tissues may imply that random continuum scattering needs to be considered in biological imaging. Between chicken breast and liver tissues, the time-gated data show that the later has stronger scattering and absorption.

© 2004 Optical Society of America

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Appl. Opt. (8)

J. Opt. Soc. Am. A (5)

Opt. Express (2)

Opt. Lett. (9)

Adam Wax, Changhuei Yang, Ramachandra R. Dasari, and Michael S. Feld, �??Measurement of angular distributions by use of low-coherence interferometry for light-scattering spectroscopy,�?? Opt. Lett. 26, 322 (2001).

Chia-Wei Sun, Chih-Yu Wang, C. C. Yang, Yean-Woei Kiang, I-Jen Hsu, and Chii-Wann Lin, �??Polarization gating in ultrafast-optics imaging of skeletal muscle tissues,�?? Opt. Lett. 26, 432 (2001).

Hsiang-Hsu Wang, Chia-Wei Sun, Yih-Ming Wang, Yean-Woei Kiang, and C. C. Yang, �??Determination of the depth of a scattering target in a turbid medium with polarization discrimination of transmitted signals,�?? Opt. Lett. 28, 25 (2003).

K. M. Yoo, B. B. Das, and R. R. Alfano, �??Imaging of a translucent object hidden in a highly scattering medium from the early portion of the diffuse component of a transmitted ultrafast laser pulse,�?? Opt. Lett. 17, 958 (1992).

Vanitha Sankaran, Joseph T. Walsh, Jr., and Duncan J. Maitland, �??Polarized light propagation through tissue phantoms containing densely packed scatterers,�?? Opt. Lett. 25, 239 (2000).

S. G. Demos and R. R. Alfano, �??Temporal gating in highly scattering media by the degree of optical polarization,�?? Opt. Lett. 21, 161 (1996).

L. Wang, X. Liang, P. Galland, P. P. Ho, and R. R. Alfano, �??True scattering coefficients of turbid matter measured by early-time gating,�?? Opt. Lett. 20, 913 (1995).

Hiromichi Horinaka, Koji Hashimoto, Kenji Wada, Yoshio Cho, and Masahiko Osawa, �??Extraction of quasi-straightforward-propagating photons from diffused light transmitting through a scattering medium by polarization modulation,�?? Opt. Lett. 20, 1501 (1995).

Vanitha Sankaran, Matthew J. Everett, Duncan J. Maitland, and Joseph T. Walsh, Jr., �??Comparison of polarized-light propagation in biological tissue and phantoms,�?? Opt. Lett. 24, 1044 (1999).

Opt. Rev. (1)

Koichi Shimizu and Masataka Kitama, �??Fundamental study on near-axis scattered light and its application to optical computed tomography,�?? Opt. Rev. 7, 383 (2000).
[CrossRef]

Science (1)

D. Huang, E. A. Swanson, C. P. Lin. J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, J. G. Fujimoto, �??Optical Coherence Tomography,�?? Science 254, 1178 (1991).
[CrossRef]

Other (1)

Akira Ishimaru, Wave Propagation and Scattering in Random Media, Vols. 1 and 2, Academic Press, Inc., New York (1978).

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