Abstract

A novel optical scheme for a phase shifting method of Fourier domain optical coherence tomography is presented. With this method we avoid a mechanical scan for phase shifting (mechanical M-scan) by using a reference beam with tilted wavefront. The principle of this system is confirmed with a simple mirror object. This method is applied on a biological sample and used to investigate a porcine anterior eye chamber.

© 2004 Optical Society of America

Full Article  |  PDF Article

References

  • View by:
  • |

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, J. G. Fujimoto, ???Optical coherence tomography,??? Science 254, 1178???1181 (1991).
    [CrossRef] [PubMed]
  2. Häusler G, Lindner MW, "???Coherence rader??? and ???spectral radar??????New tools for dermatological diagnosis,??? J. Biomed. Opt. 3, 21???31 (1998).
    [CrossRef]
  3. Maciej Wojtkowski, Tomasz Bajraszewski, Piotr Targowski, Andrzej Kowalczyk, ???Real-time in vivo imaging by high-speed spectral optical coherence tomography,??? Opt. Lett. 28, 1745???1747 (2003).
    [CrossRef] [PubMed]
  4. R. A. Leitgeb, C. K. Hitzenberger, A. F. Fercher, ???Performance of Fourier domain vs. time domain optical coherence tomography,??? Opt. Express 11, 889???894 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889</a>.
    [CrossRef] [PubMed]
  5. Y. Yasuno, S. Makita, Y. Sutoh, M. Itoh, and T. Yatagai, ???Birefringence imaging of human skin by polarization-sensitive spectral interferometric optical coherence tomography,??? Opt. Lett. 27, 1803???1805 (2002).
    [CrossRef]
  6. Yoshiaki Yasuno, Shuichi Makita, Takashi Endo, Masahide Itoh, Toyohiko Yatagai, Mari Takahashi, Chikatoshi Katada and Manabu Mutoh, ???Polarization-sensitive complex Fourier domain optical coherence tomography for Jones matrix imaging of biological samples,??? Appl. Phys. Lett. 85, 3023-3025 (2004).
    [CrossRef]
  7. Brian R. White, Mark C. Pierce, Nader Nassif, Barry Cense, B. Hyle Park, Guillermo J. Tearney, Brett E. Bouma, Teresa C. Chen, Johannes F de Boer, ???In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical coherence tomography,??? Opt. Express 11, 3490???3497 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-25-3490">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-25-3490</a>.
    [CrossRef] [PubMed]
  8. Rainer A. Leitgeb, Leopold Schmetterer, Christoph K. Hitzenberger, Adolf F. Fercher, Fatma Berisha, Maciej Wojtkowski and Tomasz Bajraszewski, ???Real-time measurement of in vitro flow by Fourier-domain color Doppler optical coherence tomography,??? Opt. Lett. 29, 171-173 (2004).
    [CrossRef] [PubMed]
  9. Y. Yasuno, Y. Sutoh, M. Nakama, S. Makita, M. Itoh, T. Yatagai, and M. Mori, ???Spectral interferometric optical coherence tomography with nonlinear ?-barium borate time gating,??? Opt. Lett. 27, 403???405 (2002).
    [CrossRef]
  10. M. Wojtkowski, A. Kowalczyk, R. Leitgeb and A. F. Fercher, ???Full range complex spectral optical coherence tomography technique in eye imaging,??? Opt. Lett. 27, 1415???1417 (2002).
    [CrossRef]
  11. E.g., J. E. Greivenkamp, J. H. Bruning, Daniel Malacara, et al., ???Optical Shop Testing,??? 2nd ed., A Wiley-Interscience Publication, Chapter 14, (1992).
  12. Joanna Schmit and Katherine Creath, ???Extended averaging technique for derivation of error-compensating algorithms in phase-shifting interferometry,??? Appl. Opt. 34, 3610???3619 (1995).
    [CrossRef] [PubMed]
  13. Andrew M. Rollins, Joseph A. Izatt, ???Optimal interferometerdesigns for optical coherence tomography,??? Opt. Lett. 24, 1484???1486 (1999).
    [CrossRef]

Appl. Opt.

Appl. Phys. Lett.

Yoshiaki Yasuno, Shuichi Makita, Takashi Endo, Masahide Itoh, Toyohiko Yatagai, Mari Takahashi, Chikatoshi Katada and Manabu Mutoh, ???Polarization-sensitive complex Fourier domain optical coherence tomography for Jones matrix imaging of biological samples,??? Appl. Phys. Lett. 85, 3023-3025 (2004).
[CrossRef]

J. Biomed. Opt.

Häusler G, Lindner MW, "???Coherence rader??? and ???spectral radar??????New tools for dermatological diagnosis,??? J. Biomed. Opt. 3, 21???31 (1998).
[CrossRef]

Opt. Express

Opt. Lett.

Science

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, J. G. Fujimoto, ???Optical coherence tomography,??? Science 254, 1178???1181 (1991).
[CrossRef] [PubMed]

Other

E.g., J. E. Greivenkamp, J. H. Bruning, Daniel Malacara, et al., ???Optical Shop Testing,??? 2nd ed., A Wiley-Interscience Publication, Chapter 14, (1992).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.

Alert me when this article is cited.


Figures (5)

Fig. 1.
Fig. 1.

The schematic diagram of the phase shifting Fourier domain OCT system. M; a mirror, BS; a beam splitter, Obj; an objective and CL; a cylindrical lens.

Fig. 2.
Fig. 2.

Schematic figure of phase offset control by the tilt of reference wavefront (i), and one-shot spectral interferogram on CCD camera.

Fig. 3.
Fig. 3.

One dimensional OCT signals measuring a mirror-surface, The signals represent a reconstructed signal without phase shifting (i) and with phase shifting (ii).

Fig. 4.
Fig. 4.

Anterior chamber of on ex-vivo porcine eye. OCT images reconstructed without phase-shifting algorithm (i), and with phase-shifting algorithm (ii).

Fig. 5.
Fig. 5.

An example of a fiber-based reference wavefront tilting FD-OCT system. The interferometer is a conventional fiber-based Mach-Zehnder interferometer, and the reference wavefront tilting is induced by the separation of two fiber tips.

Equations (6)

Equations on this page are rendered with MathJax. Learn more.

I ˜ ( ω ) = p ˜ ( ω ) 2 + r ˜ ( ω ) 2 + 2 p ˜ ( ω ) r ˜ ( ω ) cos ( ω τ d p ˜ ( ω ) + φ )
I ( τ ) = Γ [ p ( τ ) ] + Γ [ r ( τ ) ] + ( Γ [ p ( τ ) , r ( τ ) ] e i φ ) δ ( τ τ d )
+ ( Γ [ r ( τ ) , p ( τ ) ] e φ ) δ ( τ + τ d )
I ˜ ps ( ω ) = p ˜ ( ω ) r ˜ ( ω ) exp i ( ω τ d p ˜ ( ω ) ) .
I ps ( τ ) = Γ [ p ( τ ) , r ( τ ) ] δ ( τ τ d )
φ = 4 π δ L λ

Metrics