Abstract

At present, optical coherence tomography systems have a limited imaging depth or axial scan range, making diagnosis of large diameter arterial vessels and hollow organs difficult. Adaptive ranging is a feedback technique where image data is utilized to adjust the coherence gate offset and range. In this paper, we demonstrate an adaptive optical coherence tomography system with a 7.0 mm range. By matching the imaging depth to the approximately 1.5 mm penetration depth in tissue, a 3 dB sensitivity improvement over conventional imaging systems with a 3.0 mm imaging depth was realized.

© 2004 Optical Society of America

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Am. Heart J. (1)

O. R. Guerra, W. R. Janowitz, A. S. Agatston, L. L. Mantelle, M. Viamonte, Jr., �??Coronary artery diameter and coronary risk factors: a study with ultrafast computed tomography,�?? Am. Heart J. 126, 600-606 (1993).
[CrossRef]

Circulation (3)

G. J. Tearney, M. E. Brezinsky, S. A. Bopart, et al., �??Images in cardiovascular medicine: catheter based optical imaging of a human coronary artery,�?? Circulation 94, 3013 (1996).

H. Yabushita, B. E. Bouma, S. L. Houser, H. T. Aretz, I. K. Jang, K. Schlendorf, C. R. Kauffman, M. Shishkov, D. H. Kang, E. F. Halpern, G. J. Tearney, �??Characterization of human atherosclerosis by optical coherence tomography,�?? Circulation 106, 1640-1645 (2002).
[CrossRef]

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, B. E. Bouma, �??Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,�?? Circulation 107, 113-119 (2003).
[CrossRef]

Dermatology (1)

J. M. Schmitt, M. J. Yadlowsky, R. F. Bonner, �??Subsurface imaging of living skin with optical coherence microscopy,�?? Dermatology 191, 93-98 (1995).

Gastrointest. Endosc. (1)

B. E. Bouma, G. J. Tearney, C. C. Compton, N. S. Nishioka, �??High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography,�?? Gastrointest. Endosc. 51, 464-474 (2000).
[CrossRef]

Gastrointestinal Endoscopy (1)

M. V. Sivak, Jr., K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Ung-Runyawee, A. Chak, R. C. Wong, G. A. Isenberg, J. Willis, �??High-resolution endoscopic imaging of the GI tract using optical coherence tomography,�?? Gastrointestinal Endoscopy 51, 474-479 (2000).
[CrossRef]

IEEE J. Sel. Top. Quantum Electron. (1)

J. A. Izatt, M. D. Kulkarni, H. W. Wang, K. Kobayashi, M. V. Sivak, Jr., �??Optical coherence tomography and microscopy in gastrointestinal tissues,�?? IEEE J. of Sel. Top. Quantum Electron. 2, 1017-1028 (1996).

Invest. Ophthalmol. Vis. Sci. (1)

C. Strom, B. Sander, N. Larsen, M. Larsen, H.Lund-Andersen, �??Diabetic macular edema assessed with optical coherence tomography and stereo fundus photography,�?? Invest. Ophthalmol. Vis. Sci. 43, 241-245 (2002).

J. Am. College Cardiology (1)

I. K. Jang, B. E. Bouma, D. H. Kang, S. J. Park, S. W. Park, K. B. Seung, K. B. Choi, M. Shishkov, K. Schlendorf, E. Pomerantsev, S. L. Houser, H. T. Aretz, G. J. Tearney, �??Visualization of coronary atherosclerotic plaques in patients using optical coherence tomography,�?? J. Am. College Cardiology 39, 604-609 (2002).
[CrossRef]

J. Biomed. Opt. (1)

B. Cense, T. C. Chen, B.H. Park, M. C. Pierce, and J. F. de Boer, "In vivo birefringence and thickness measurements of the human retinal nerve fiber layer using polarization-sensitive optical coherence tomography,�?? J. Biomed. Opt. 9, 121-125 (2004).
[CrossRef]

J. Mod. Opt. (1)

F. Lexer, C.K. Hitzenberger, W. Drexler, S. Molebny, H. Sattmann, M. Sticker, A. F. Fercher, �??Dynamic coherent focus OCT with depth-independent transversal resolution," J. Mod. Opt. 46, 541-553(1999).

Obstet. Gynecol. (1)

C. Pitris, A. Goodman, S. A. Bopart, J. J. Libus, J. G. Fujimoto, M. E. Brezinski, �??High-resolution imaging of gynecologic neoplasms using optical coherence tomography,�?? Obstet. Gynecol. 93, 135-139 (1999).
[CrossRef]

Opt. Commun. (2)

J.M. Schmitt, S.L. Lee, K.M. Yung, �??An optical coherence microscope with enhanced power in thick tissue,�?? Opt. Commun. 142, 203-207 (1997).
[CrossRef]

B.Qi, A.P. Himmer, L.M. Gordon, X.D. V. Yang, L.D. Dickensheets, I. A. Vitkin, �??Dynamic focus control in a high-speed optical coherence tomography based on a micromechanical mirror,�?? Opt. Commun. 232, 123-128(2004).
[CrossRef]

Opt. Express (1)

Opt. Lett. (3)

Rep. Progr. Phys. (1)

A. F. Fercher, W. Drexler, C.K. Hitzenberger,and T. Lasser, �??Optical Coherence tomography-principles and applications,�?? Rep. Progr. Phys. 66, 239-303 (2003).

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, �??Optical coherence tomography,�?? Science 254, 1178-1181 (1991).
[CrossRef]

Semin. Ophthalmol. (1)

A.M. Coppe, G. Ripandelli, �??Optical coherence tomography in the evaluation of vitreoretinal disorders of the macula in highly myopic eyes,�?? Semin. Ophthalmol. 2, 85-88(2003).

Other (2)

J. Kauppinen, J. Partanen, Fourier Transforms in Spectroscopy, ed.(Wiley-VCH, March 2001).

J. M. Poneros, G. J. Tearney, B. E. Bouma, G. Y. Lauwers, N. S. Nishioka, �??Diagnosis of dysplasia in Barrett�??s esophagus using optical coherence tomography,�?? In: Digestive Disease Week, San Francisco, CA. American Gastroenterological Association, AB113 (2001).

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