Abstract

An experimental standard optical coherence tomography (OCT) setup that can be easily modified for cross-polarization OCT (CP OCT) operation has been developed to perform differential diagnosis of pathological tissues. The complementary use of CP OCT, a technique that provides a map of cross-polarization backscattering properties of an object being studied by means of low-coherence interferometry, and standard OCT imaging improves the specificity of diagnostics of pathological changes occurring in tissues. It is shown that healthy, neoplastic and scar tissues of the esophagus have different cross-polarization backscattering properties. A comparative analysis of CP OCT, OCT and histological images from one and the same tissue area has been made. A close correlation between the location of collagen fibers in biological tissue and signal intensity in CP OCT images is found.

© 2001 Optical Society of America

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2002 (3)

N.M. Shakhova, V.M. Gelikonov, V.A. Kamensky, R.V. Kuranov, and I.V. Turchin, “Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value,” Laser Physics 12, 617–626, (2002).

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

2001 (3)

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

2000 (4)

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

S.L. Jacques, J.R. Roman, and K. Lee, “Imaging superficial tissues with polarized light,” Lasers Sur. Med. 26, 119–129, (2000).
[Crossref]

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

1999 (3)

J.M. Schmitt, “Optical Coherence Tomography (OCT): A Review,” IEEE J. Sel. Top. Quantum Electron. 5, 1205–1215, (1999).
[Crossref]

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

M.E. Brezinski and J.G. Fujimoto, “Optical Coherence Tomography: High-Resolution Imaging in Nontransparent Tissue,” IEEE J. Sel. Top. Quantum Electron. 5, 1185–1192, (1999).
[Crossref]

1998 (4)

1997 (1)

D.J. Maitland and J.T. Walsh, “Quantitative measurements of linear birefringence during heating of native collagen,” Lasers Sur. Med. 20, 310–318, (1997).
[Crossref]

1995 (1)

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

1991 (1)

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

1987 (1)

V.M. Gelikonov, D.D. Gusovskii, V.I. Leonov, and M.A. Novikov, “Birefringence compensation in single-mode optical fibers,” Sov. Tech. Phys. Lett. 13, 322–323, (1987).

Baumgartner, A.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Boppart, S.A.

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

Brezinski, M.E.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

M.E. Brezinski and J.G. Fujimoto, “Optical Coherence Tomography: High-Resolution Imaging in Nontransparent Tissue,” IEEE J. Sel. Top. Quantum Electron. 5, 1185–1192, (1999).
[Crossref]

Chang, W.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Chen, Z.P.

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

J.F. de Boer, S.M. Srinivas, A. Malekafzali, Z.P. Chen, and J.S. Nelson, “Imaging thermally damaged tissue by polarization sensitive optical coherence tomography,” Opt. Express 3, 212–218, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-212.
[Crossref] [PubMed]

Colston, B.W.

Conwell, D.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

DaSilva, L.B.

Davros, B.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

de Boer, J.F.

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

J.F. de Boer, S.M. Srinivas, A. Malekafzali, Z.P. Chen, and J.S. Nelson, “Imaging thermally damaged tissue by polarization sensitive optical coherence tomography,” Opt. Express 3, 212–218, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-212.
[Crossref] [PubMed]

Dichtl, S.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Donchenko, E.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Drexler, W.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

Dumot, J.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Everett, M.J.

Falk, G.W.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Feldchtein, F.I.

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

F.I. Feldchtein, G.V. Gelikonov, V.M. Gelikonov, R.R. Iksanov, R.V. Kuranov, A.M. Sergeev, N.D. Gladkova, M.N. Ourutina, J.A. Warren., and D.H. Reitze, “In vivo imaging of hard and soft tissue of the oral cavity,” Opt. Express 3, 239–250, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-239.
[Crossref] [PubMed]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Fercher, Z.F.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Flotte, T.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Fujimoto, J.G.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

M.E. Brezinski and J.G. Fujimoto, “Optical Coherence Tomography: High-Resolution Imaging in Nontransparent Tissue,” IEEE J. Sel. Top. Quantum Electron. 5, 1185–1192, (1999).
[Crossref]

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Gelikonov, G.V.

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

F.I. Feldchtein, G.V. Gelikonov, V.M. Gelikonov, R.R. Iksanov, R.V. Kuranov, A.M. Sergeev, N.D. Gladkova, M.N. Ourutina, J.A. Warren., and D.H. Reitze, “In vivo imaging of hard and soft tissue of the oral cavity,” Opt. Express 3, 239–250, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-239.
[Crossref] [PubMed]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Gelikonov, V.M

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

Gelikonov, V.M.

N.M. Shakhova, V.M. Gelikonov, V.A. Kamensky, R.V. Kuranov, and I.V. Turchin, “Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value,” Laser Physics 12, 617–626, (2002).

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

F.I. Feldchtein, G.V. Gelikonov, V.M. Gelikonov, R.R. Iksanov, R.V. Kuranov, A.M. Sergeev, N.D. Gladkova, M.N. Ourutina, J.A. Warren., and D.H. Reitze, “In vivo imaging of hard and soft tissue of the oral cavity,” Opt. Express 3, 239–250, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-239.
[Crossref] [PubMed]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

V.M. Gelikonov, D.D. Gusovskii, V.I. Leonov, and M.A. Novikov, “Birefringence compensation in single-mode optical fibers,” Sov. Tech. Phys. Lett. 13, 322–323, (1987).

Gladkova, N.D.

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

F.I. Feldchtein, G.V. Gelikonov, V.M. Gelikonov, R.R. Iksanov, R.V. Kuranov, A.M. Sergeev, N.D. Gladkova, M.N. Ourutina, J.A. Warren., and D.H. Reitze, “In vivo imaging of hard and soft tissue of the oral cavity,” Opt. Express 3, 239–250, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-239.
[Crossref] [PubMed]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Goldblum, J.R.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Gregory, K.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Gusovskii, D.D.

V.M. Gelikonov, D.D. Gusovskii, V.I. Leonov, and M.A. Novikov, “Birefringence compensation in single-mode optical fibers,” Sov. Tech. Phys. Lett. 13, 322–323, (1987).

Hee, M.R.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Hitzenberger, C.K.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Huang, D.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Iksanov, R.R.

Jacques, S.L.

S.L. Jacques, J.R. Roman, and K. Lee, “Imaging superficial tissues with polarized light,” Lasers Sur. Med. 26, 119–129, (2000).
[Crossref]

Jesser, C.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

Kamensky, V.A.

N.M. Shakhova, V.M. Gelikonov, V.A. Kamensky, R.V. Kuranov, and I.V. Turchin, “Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value,” Laser Physics 12, 617–626, (2002).

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

Khanin, Ya.I.

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Kuranov, R.V.

N.M. Shakhova, V.M. Gelikonov, V.A. Kamensky, R.V. Kuranov, and I.V. Turchin, “Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value,” Laser Physics 12, 617–626, (2002).

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

F.I. Feldchtein, G.V. Gelikonov, V.M. Gelikonov, R.R. Iksanov, R.V. Kuranov, A.M. Sergeev, N.D. Gladkova, M.N. Ourutina, J.A. Warren., and D.H. Reitze, “In vivo imaging of hard and soft tissue of the oral cavity,” Opt. Express 3, 239–250, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-239.
[Crossref] [PubMed]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Lee, K.

S.L. Jacques, J.R. Roman, and K. Lee, “Imaging superficial tissues with polarized light,” Lasers Sur. Med. 26, 119–129, (2000).
[Crossref]

Leonov, V.I.

V.M. Gelikonov, D.D. Gusovskii, V.I. Leonov, and M.A. Novikov, “Birefringence compensation in single-mode optical fibers,” Sov. Tech. Phys. Lett. 13, 322–323, (1987).

Li, X.D.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

Lillie, R.D.

R.D. Lillie, Histopathologic technic and practical histochemistry (McGraw-Hill book company, New York-Toronto-Sydney-London, 1965), Chap. 15, or http://www.ebsciences.com/staining/van_gies.htm.

Lin, C.P.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Lodge, M.B.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

Maitland, D.J.

Malekafzali, A.

Martin, S.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

Milner, T.E.

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

Moritz, A.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Morozov, A.N.

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

Nasonova, V.A.

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

Nelson, J.S.

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

J.F. de Boer, S.M. Srinivas, A. Malekafzali, Z.P. Chen, and J.S. Nelson, “Imaging thermally damaged tissue by polarization sensitive optical coherence tomography,” Opt. Express 3, 212–218, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-212.
[Crossref] [PubMed]

Nikulin, N.K.

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Novikov, M.A.

V.M. Gelikonov, D.D. Gusovskii, V.I. Leonov, and M.A. Novikov, “Birefringence compensation in single-mode optical fibers,” Sov. Tech. Phys. Lett. 13, 322–323, (1987).

Ourutina, M.N.

Park, B.H.

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

Petrova, G.A.

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Pham, T.H.

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

Pitris, C.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

Pochinko, V.V.

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Ponsky, J.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Pravdenko, K.I.

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Puliafito, C.A.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Radenska-Lopovok, S.G.

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

Reitze, D.H.

Richter, J.E.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Robl, B.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Roman, J.R.

S.L. Jacques, J.R. Roman, and K. Lee, “Imaging superficial tissues with polarized light,” Lasers Sur. Med. 26, 119–129, (2000).
[Crossref]

Sattmann, H.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Saunders, K.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

Schmitt, J.M.

J.M. Schmitt, “Optical Coherence Tomography (OCT): A Review,” IEEE J. Sel. Top. Quantum Electron. 5, 1205–1215, (1999).
[Crossref]

J.M. Schmitt and S.H. Xiang, “Cross-polarized backscatter in optical coherence tomography of biological tissue,” Opt. Lett. 23, 1060–1062, (1998).
[Crossref]

Schoenenberger, K.

Sergeev, A.M.

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

F.I. Feldchtein, G.V. Gelikonov, V.M. Gelikonov, R.R. Iksanov, R.V. Kuranov, A.M. Sergeev, N.D. Gladkova, M.N. Ourutina, J.A. Warren., and D.H. Reitze, “In vivo imaging of hard and soft tissue of the oral cavity,” Opt. Express 3, 239–250, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-239.
[Crossref] [PubMed]

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Shabanov, D.V.

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Shakhov, A.V.

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

Shakhova, N.M.

N.M. Shakhova, V.M. Gelikonov, V.A. Kamensky, R.V. Kuranov, and I.V. Turchin, “Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value,” Laser Physics 12, 617–626, (2002).

Shuman, J. S.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Snopova, L.B.

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

Sperr, W.

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

Srinivas, S.M.

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

J.F. de Boer, S.M. Srinivas, A. Malekafzali, Z.P. Chen, and J.S. Nelson, “Imaging thermally damaged tissue by polarization sensitive optical coherence tomography,” Opt. Express 3, 212–218, (1998), http://www.opticsexpress.org/abstract.cfm?URI=OPEX-3-6-212.
[Crossref] [PubMed]

Stamper, D.

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

Stemper, D.

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

Stinson, W.G.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Streltsova, O.S.

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

Terentjeva, A.B.

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

Terentyeva, A.B.

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

Turchin, I.V.

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

N.M. Shakhova, V.M. Gelikonov, V.A. Kamensky, R.V. Kuranov, and I.V. Turchin, “Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value,” Laser Physics 12, 617–626, (2002).

Vargo, J.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Walsh, J.T.

D.J. Maitland and J.T. Walsh, “Quantitative measurements of linear birefringence during heating of native collagen,” Lasers Sur. Med. 20, 310–318, (1997).
[Crossref]

Wang, J.

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Warren., J.A.

Xiang, S.H.

Zagaynova, E.V.

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Zuccaro, G.

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Am. J. Gastroenter. (1)

G. Zuccaro, N.D. Gladkova, J. Vargo, F.I. Feldchtein, E.V. Zagaynova, D. Conwell, G.W. Falk, J.R. Goldblum, J. Dumot, J. Ponsky, G.V. Gelikonov, B. Davros, E. Donchenko, and J.E. Richter, “Optical coherence tomography of the esophagus and proximal stomach in health and disease,” Am. J. Gastroenter. 96, 2633–2639, (2001).
[Crossref] [PubMed]

Appl. Opt. (1)

Caries Research (1)

A. Baumgartner, S. Dichtl, C.K. Hitzenberger, H. Sattmann, B. Robl, A. Moritz, Z.F. Fercher, and W. Sperr, “Polarization-sensitive optical coherence tomography of dental structures,” Caries Research 34, 59–69, (2000).
[Crossref]

IEEE J. Sel. Top. Quantum Electron. (3)

J.M. Schmitt, “Optical Coherence Tomography (OCT): A Review,” IEEE J. Sel. Top. Quantum Electron. 5, 1205–1215, (1999).
[Crossref]

M.E. Brezinski and J.G. Fujimoto, “Optical Coherence Tomography: High-Resolution Imaging in Nontransparent Tissue,” IEEE J. Sel. Top. Quantum Electron. 5, 1185–1192, (1999).
[Crossref]

J.F. de Boer, S.M. Srinivas, B.H. Park, T.H. Pham, Z.P. Chen, T.E. Milner, and J.S. Nelson, “Polarization effects in optical coherence tomography of various biological tissues,” IEEE J. Sel. Top. Quantum Electron. 5, 1200–1204, (1999).
[Crossref]

J. Gastroenterol. (1)

C. Pitris, C. Jesser, S.A. Boppart, D. Stemper, M.E. Brezinski, and J.G. Fujimoto, “Feasibility of optical coherence tomography for high-resolution imaging of human gastrointestinal tract malignancies,” J. Gastroenterol. 35, 87–92, (2000).
[Crossref] [PubMed]

J. Rheumatol. (1)

W. Drexler, D. Stamper, C. Jesser, X.D. Li, C. Pitris, K. Saunders, S. Martin, M.B. Lodge, J.G. Fujimoto, and M.E. Brezinski, “Correlation of collagen organization with polarization sensitive imaging of in vitro cartilage: Implications for osteoarthritis,” J. Rheumatol. 28, 1311–1318, (2001).
[PubMed]

J. Surg. Oncology (1)

A.V. Shakhov, A.B. Terentjeva, V.A. Kamensky, L.B. Snopova, V.M. Gelikonov, F.I. Feldchtein, and A.M. Sergeev, “Optical Coherence Tomography Monitoring for Laser Surgery of Laryngeal Carcinoma,” J. Surg. Oncology 77, 253–259, (2001).
[Crossref]

J. Urology (1)

E.V. Zagaynova, O.S. Streltsova, N.D. Gladkova, L.B. Snopova, G.V. Gelikonov, F.I. Feldchtein, and A.N. Morozov, “In vivo optical coherence tomography feasibility for bladder disease,” J. Urology 167, 1492–1496, (2002).
[Crossref]

JETP Lett. (1)

V.M. Gelikonov, G.V. Gelikonov, R.V. Kuranov, K.I. Pravdenko, A.M. Sergeev, F.I. Feldchtein, Ya.I. Khanin, D.V. Shabanov, N.D. Gladkova, N.K. Nikulin, G.A. Petrova, and V.V. Pochinko, “Coherent optical tomography of microscopic inhomogeneties in biological tissues,” JETP Lett. 61, 158–162, (1995).

Laser Physics (1)

N.M. Shakhova, V.M. Gelikonov, V.A. Kamensky, R.V. Kuranov, and I.V. Turchin, “Clinical aspects of the endoscopic optical coherence tomography and the ways for improving its diagnostic value,” Laser Physics 12, 617–626, (2002).

Lasers Sur. Med. (2)

S.L. Jacques, J.R. Roman, and K. Lee, “Imaging superficial tissues with polarized light,” Lasers Sur. Med. 26, 119–129, (2000).
[Crossref]

D.J. Maitland and J.T. Walsh, “Quantitative measurements of linear birefringence during heating of native collagen,” Lasers Sur. Med. 20, 310–318, (1997).
[Crossref]

Opt. Express (2)

Opt. Lett. (1)

OSA Biomed. Top. Meeting, OSA Tech. Digest (1)

R.V. Kuranov, V.M. Gelikonov, A.V. Shakhov, A.B. Terentyeva, I.V. Turchin, and V.A. Kamensky, “Mapping depolarization properties of biotissues for increasing specificity of OCT,” in OSA Biomed. Top. Meeting, OSA Tech. Digest, (Optical Society of America, Washington DC, 2002), pp.275–277.

Science (1)

D. Huang, J. Wang, C.P. Lin, J. S. Shuman, W.G. Stinson, W. Chang, M.R. Hee, T. Flotte, K. Gregory, C.A. Puliafito, and J.G. Fujimoto, “Optical coherence tomography,” Science 254, 1178–1181, (1991).
[Crossref] [PubMed]

Skin Research and Technology (1)

N.D. Gladkova, G.A. Petrova, N.K. Nikulin, S.G. Radenska-Lopovok, L.B. Snopova, V.A. Nasonova, G.V. Gelikonov, V.M Gelikonov, R.V. Kuranov, A.M. Sergeev, and F.I. Feldchtein,“In vivo optical coherence tomography imaging of human skin: norm and pathology,” Skin Research and Technology 6, 6–16, (2000).
[Crossref]

Sov. Tech. Phys. Lett. (1)

V.M. Gelikonov, D.D. Gusovskii, V.I. Leonov, and M.A. Novikov, “Birefringence compensation in single-mode optical fibers,” Sov. Tech. Phys. Lett. 13, 322–323, (1987).

Other (1)

R.D. Lillie, Histopathologic technic and practical histochemistry (McGraw-Hill book company, New York-Toronto-Sydney-London, 1965), Chap. 15, or http://www.ebsciences.com/staining/van_gies.htm.

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Figures (5)

Fig. 1.
Fig. 1.

Standard OCT images printed in logarithmic scale of different diseases a) laryngitis (chronic inflammation of larynx) b) laryngeal cancer c) laryngeal papilloma. White bar corresponds to 1 mm.

Fig.2
Fig.2

The experimental setup for the cross-polarization OCT. CS – crossectional scanner, O – investigated object, PS – longitudinal piezo-scanner, L – lenses, PD – photodiode, SA – selective amplifier, LA – logarithmic amplifier, AD – amplitude detector, ADC – analog to digital converter, PC – personal computer. Bold line corresponds to single-mode fiber, thin line - to polarization maintaining fiber.

Fig. 3.
Fig. 3.

a) Standard OCT image, b) CP OCT image c) H&E histology d), e) Van Gieson histology of healthy esophagus. White bar corresponds to 1 mm.

Fig. 4.
Fig. 4.

a) Standard OCT image, b) CP OCT image c) H&E histology d),e) Van Gieson histology of cancerous esophagus. White bar corresponds to 1 mm where not specially marked.

Fig. 5.
Fig. 5.

a) Standard OCT image, b) CP OCT image c) H&E histology d),e) Van Gieson histology of scar esophagus. White bar corresponds to 1 mm where not specially marked.

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