Abstract

We report experimental results of label-free anti-bovine serum albumin (anti-BSA) antibody detection using a SOI planar photonic crystal waveguide previously bio-functionalized with complementary BSA antigen probes. Sharp fringes appearing in the slow-light regime near the edge of the guided band are used to perform the sensing. We have modeled the presence of these band edge fringes and demonstrated the possibility of using them for sensing purposes by performing refractive index variations detection, achieving a sensitivity of 174.8 nm/RIU. Then, label-free anti-BSA biosensing experiments have been carried out, estimating a surface mass density detection limit below 2.1 pg/mm2 and a total mass detection limit below 0.2 fg.

© 2010 OSA

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2010 (3)

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

T. Xu, N. Zhu, M. Y.-C. Xu, L. Wosinski, J. S. Aitchison, and H. E. Ruda, “Pillar-array based optical sensor,” Opt. Express 18(6), 5420–5425 (2010), http://www.opticsinfobase.org/abstract.cfm?URI=oe-18-6-5420 .
[CrossRef] [PubMed]

2009 (5)

L. J. Kauppinen, H. J. W. M. Hoekstra, and R. M. de Ridder, “A compact refractometric sensor based on grated silicon photonic wires,” Sens. Actuators B Chem. 139(1), 194–198 (2009).
[CrossRef]

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

A. Densmore, M. Vachon, D.-X. Xu, S. Janz, R. Ma, Y.-H. Li, G. Lopinski, A. Delâge, J. Lapointe, C. C. Luebbert, Q. Y. Liu, P. Cheben, and J. H. Schmid, “Silicon photonic wire biosensor array for multiplexed real-time and label-free molecular detection,” Opt. Lett. 34(23), 3598–3600 (2009).
[CrossRef] [PubMed]

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

2008 (4)

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

C. A. Barrios, M. J. Bañuls, V. González-Pedro, K. B. Gylfason, B. Sánchez, A. Griol, A. Maquieira, H. Sohlström, M. Holgado, and R. Casquel, “Label-free optical biosensing with slot-waveguides,” Opt. Lett. 33(7), 708–710 (2008).
[CrossRef] [PubMed]

T. F. Krauss, “Why do we need slow light?” Nat. Photonics 2(8), 448–450 (2008).
[CrossRef]

G. Gupta, M. Sugimoto, Y. Matsui, and J. Kondoh, “Use of a low refractive index prism in surface plasmon resonance biosensing,” Sens. Actuators B Chem. 130(2), 689–695 (2008).
[CrossRef]

2007 (3)

2006 (2)

J. García, P. Sanchis, and J. Martí, “Detailed analysis of the influence of structure length on pulse propagation through finite-size photonic crystal waveguides,” Opt. Express 14(15), 6879–6893 (2006), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-14-15-6879 .
[CrossRef] [PubMed]

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

2005 (1)

P. Sanchis, J. Martí, P. Bienstman, and R. Baets, “Semi-analytic approach for analyzing coupling issues in photonic crystal structures,” Appl. Phys. Lett. 87(20), 203107 (2005).
[CrossRef]

1997 (2)

J. Rheims, J. Köser, and T. Wriedt, “Refractive-index measurements in the near-IR using an Abbe refractometer,” Meas. Sci. Technol. 8(6), 601–605 (1997).
[CrossRef]

Th. Schubert, N. Haase, H. Kück, and R. Gottfried-Gottfried, “Refractive-index measurements using an integrated Mach-Zehnder interferometer,” Sens. Actuators A Phys. 60(1-3), 108–112 (1997).
[CrossRef]

1996 (1)

1990 (1)

P. Schiebener, J. Straub, J. M. H. Levelt Sengers, and J. S. Gallagher, “Refractive index of water and steam as function of wavelength, temperature and density,” J. Phys. Chem. Ref. Data 19(3), 677–717 (1990).
[CrossRef]

Abstreiter, G.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Aitchison, J. S.

Baehr-Jones, T.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Baets, R.

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

K. De Vos, I. Bartolozzi, E. Schacht, P. Bienstman, and R. Baets, “Silicon-on-Insulator microring resonator for sensitive and label-free biosensing,” Opt. Express 15(12), 7610–7615 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-12-7610 .
[CrossRef] [PubMed]

P. Sanchis, J. Martí, P. Bienstman, and R. Baets, “Semi-analytic approach for analyzing coupling issues in photonic crystal structures,” Appl. Phys. Lett. 87(20), 203107 (2005).
[CrossRef]

Bailey, R. C.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Bañuls, M. J.

Bañuls Polo, M. J.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Barrios, C. A.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

C. A. Barrios, M. J. Bañuls, V. González-Pedro, K. B. Gylfason, B. Sánchez, A. Griol, A. Maquieira, H. Sohlström, M. Holgado, and R. Casquel, “Label-free optical biosensing with slot-waveguides,” Opt. Lett. 33(7), 708–710 (2008).
[CrossRef] [PubMed]

Bartolozzi, I.

Bienstman, P.

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

K. De Vos, I. Bartolozzi, E. Schacht, P. Bienstman, and R. Baets, “Silicon-on-Insulator microring resonator for sensitive and label-free biosensing,” Opt. Express 15(12), 7610–7615 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-12-7610 .
[CrossRef] [PubMed]

P. Sanchis, J. Martí, P. Bienstman, and R. Baets, “Semi-analytic approach for analyzing coupling issues in photonic crystal structures,” Appl. Phys. Lett. 87(20), 203107 (2005).
[CrossRef]

Blanco, F. J.

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

Borel, P. I.

Burr, G. W.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Bynum, M. A.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Carlborg, C. F.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Casquel, R.

Cheben, P.

Chen, W.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Chow, E.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Chu, S. T.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Clarke, J.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

de Ridder, R. M.

L. J. Kauppinen, H. J. W. M. Hoekstra, and R. M. de Ridder, “A compact refractometric sensor based on grated silicon photonic wires,” Sens. Actuators B Chem. 139(1), 194–198 (2009).
[CrossRef]

De Vos, K.

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

K. De Vos, I. Bartolozzi, E. Schacht, P. Bienstman, and R. Baets, “Silicon-on-Insulator microring resonator for sensitive and label-free biosensing,” Opt. Express 15(12), 7610–7615 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-12-7610 .
[CrossRef] [PubMed]

Delâge, A.

Densmore, A.

Domínguez, C.

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

Dorfner, D.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Dortu, F.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Esener, S.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Fauchet, P. M.

Finley, J.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Flood, E. M.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Frandsen, L.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Frandsen, L. H.

Gallagher, J. S.

P. Schiebener, J. Straub, J. M. H. Levelt Sengers, and J. S. Gallagher, “Refractive index of water and steam as function of wavelength, temperature and density,” J. Phys. Chem. Ref. Data 19(3), 677–717 (1990).
[CrossRef]

García, J.

Gill, D.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Girones, J.

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

Gleeson, M. A.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Goad, D.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

González-Pedro, V.

Gottfried-Gottfried, R.

Th. Schubert, N. Haase, H. Kück, and R. Gottfried-Gottfried, “Refractive-index measurements using an integrated Mach-Zehnder interferometer,” Sens. Actuators A Phys. 60(1-3), 108–112 (1997).
[CrossRef]

Griol, A.

Grot, A.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Gunn, L. C.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Gunn, W. G.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Gupta, G.

G. Gupta, M. Sugimoto, Y. Matsui, and J. Kondoh, “Use of a low refractive index prism in surface plasmon resonance biosensing,” Sens. Actuators B Chem. 130(2), 689–695 (2008).
[CrossRef]

Gylfason, K. B.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

C. A. Barrios, M. J. Bañuls, V. González-Pedro, K. B. Gylfason, B. Sánchez, A. Griol, A. Maquieira, H. Sohlström, M. Holgado, and R. Casquel, “Label-free optical biosensing with slot-waveguides,” Opt. Lett. 33(7), 708–710 (2008).
[CrossRef] [PubMed]

Haase, N.

Th. Schubert, N. Haase, H. Kück, and R. Gottfried-Gottfried, “Refractive-index measurements using an integrated Mach-Zehnder interferometer,” Sens. Actuators A Phys. 60(1-3), 108–112 (1997).
[CrossRef]

Harris, R. D.

Hauke, N.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Hochberg, M.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Hoekstra, H. J. W. M.

L. J. Kauppinen, H. J. W. M. Hoekstra, and R. M. de Ridder, “A compact refractometric sensor based on grated silicon photonic wires,” Sens. Actuators B Chem. 139(1), 194–198 (2009).
[CrossRef]

Holgado, M.

Hryniewicz, J. V.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Hürlimann, T.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Iqbal, M.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Ja, S. J.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Janz, S.

Kauppinen, L. J.

L. J. Kauppinen, H. J. W. M. Hoekstra, and R. M. de Ridder, “A compact refractometric sensor based on grated silicon photonic wires,” Sens. Actuators B Chem. 139(1), 194–198 (2009).
[CrossRef]

Kazmierczak, A.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

King, O.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Kjems, J.

Knobbe, E.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Kondoh, J.

G. Gupta, M. Sugimoto, Y. Matsui, and J. Kondoh, “Use of a low refractive index prism in surface plasmon resonance biosensing,” Sens. Actuators B Chem. 130(2), 689–695 (2008).
[CrossRef]

Köser, J.

J. Rheims, J. Köser, and T. Wriedt, “Refractive-index measurements in the near-IR using an Abbe refractometer,” Meas. Sci. Technol. 8(6), 601–605 (1997).
[CrossRef]

Krauss, T. F.

T. F. Krauss, “Why do we need slow light?” Nat. Photonics 2(8), 448–450 (2008).
[CrossRef]

Kresbach, G. M.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Kristensen, M.

Kück, H.

Th. Schubert, N. Haase, H. Kück, and R. Gottfried-Gottfried, “Refractive-index measurements using an integrated Mach-Zehnder interferometer,” Sens. Actuators A Phys. 60(1-3), 108–112 (1997).
[CrossRef]

Lapointe, J.

Lechuga, L. M.

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

Lee, M. R.

Levelt Sengers, J. M. H.

P. Schiebener, J. Straub, J. M. H. Levelt Sengers, and J. S. Gallagher, “Refractive index of water and steam as function of wavelength, temperature and density,” J. Phys. Chem. Ref. Data 19(3), 677–717 (1990).
[CrossRef]

Li, Y.-H.

Little, B. E.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Liu, Q. Y.

Lopinski, G.

Luebbert, C. C.

Luff, B. J.

Ma, R.

Maquieira, A.

Maquieira Catala, A.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Martí, J.

Matsui, Y.

G. Gupta, M. Sugimoto, Y. Matsui, and J. Kondoh, “Use of a low refractive index prism in surface plasmon resonance biosensing,” Sens. Actuators B Chem. 130(2), 689–695 (2008).
[CrossRef]

Mayora, K.

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

Mirkarimi, L. W.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Moh, T.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Moreno, M.

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

Popelka, S.

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

Popplewell, J.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Ramachandran, A.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Rant, U.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Rheims, J.

J. Rheims, J. Köser, and T. Wriedt, “Refractive-index measurements in the near-IR using an Abbe refractometer,” Meas. Sci. Technol. 8(6), 601–605 (1997).
[CrossRef]

Río, J. S.

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

Robotti, K. M.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Ronan, G.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Ruda, H. E.

Sánchez, B.

Sanchis, P.

Schacht, E.

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

K. De Vos, I. Bartolozzi, E. Schacht, P. Bienstman, and R. Baets, “Silicon-on-Insulator microring resonator for sensitive and label-free biosensing,” Opt. Express 15(12), 7610–7615 (2007), http://www.opticsinfobase.org/oe/abstract.cfm?URI=oe-15-12-7610 .
[CrossRef] [PubMed]

Schiebener, P.

P. Schiebener, J. Straub, J. M. H. Levelt Sengers, and J. S. Gallagher, “Refractive index of water and steam as function of wavelength, temperature and density,” J. Phys. Chem. Ref. Data 19(3), 677–717 (1990).
[CrossRef]

Schiffrin, D. J.

Schmid, J. H.

Schubert, Th.

Th. Schubert, N. Haase, H. Kück, and R. Gottfried-Gottfried, “Refractive-index measurements using an integrated Mach-Zehnder interferometer,” Sens. Actuators A Phys. 60(1-3), 108–112 (1997).
[CrossRef]

Sepúlveda, B.

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

Sigalas, M. M.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Skivesen, N.

Sohlström, H.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

C. A. Barrios, M. J. Bañuls, V. González-Pedro, K. B. Gylfason, B. Sánchez, A. Griol, A. Maquieira, H. Sohlström, M. Holgado, and R. Casquel, “Label-free optical biosensing with slot-waveguides,” Opt. Lett. 33(7), 708–710 (2008).
[CrossRef] [PubMed]

Spaugh, B.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Stemme, G.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Straub, J.

P. Schiebener, J. Straub, J. M. H. Levelt Sengers, and J. S. Gallagher, “Refractive index of water and steam as function of wavelength, temperature and density,” J. Phys. Chem. Ref. Data 19(3), 677–717 (1990).
[CrossRef]

Sugimoto, M.

G. Gupta, M. Sugimoto, Y. Matsui, and J. Kondoh, “Use of a low refractive index prism in surface plasmon resonance biosensing,” Sens. Actuators B Chem. 130(2), 689–695 (2008).
[CrossRef]

Têtu, A.

Tybor, F.

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

Vachon, M.

van der Wijngaart, W.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Vivien, L.

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Wald, L.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Wang, S.

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

Wilkinson, J. S.

Wilson, R.

Wosinski, L.

Wriedt, T.

J. Rheims, J. Köser, and T. Wriedt, “Refractive-index measurements in the near-IR using an Abbe refractometer,” Meas. Sci. Technol. 8(6), 601–605 (1997).
[CrossRef]

Xu, D.-X.

Xu, M. Y.-C.

Xu, T.

Zabel, T.

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

Zhu, N.

Zlatanovic, S.

S. Zlatanovic, L. W. Mirkarimi, M. M. Sigalas, M. A. Bynum, E. Chow, K. M. Robotti, G. W. Burr, S. Esener, and A. Grot, “Photonic crystal microcavity sensor for ultracompact monitoring of reaction kinetics and protein concentration,” Sens. Actuators B Chem. 141(1), 13–19 (2009).
[CrossRef]

Appl. Phys. Lett. (1)

P. Sanchis, J. Martí, P. Bienstman, and R. Baets, “Semi-analytic approach for analyzing coupling issues in photonic crystal structures,” Appl. Phys. Lett. 87(20), 203107 (2005).
[CrossRef]

Biosens. Bioelectron. (3)

K. De Vos, J. Girones, S. Popelka, E. Schacht, R. Baets, and P. Bienstman, “SOI optical microring resonator with poly(ethylene glycol) polymer brush for label-free biosensor applications,” Biosens. Bioelectron. 24(8), 2528–2533 (2009).
[CrossRef] [PubMed]

A. Ramachandran, S. Wang, J. Clarke, S. J. Ja, D. Goad, L. Wald, E. M. Flood, E. Knobbe, J. V. Hryniewicz, S. T. Chu, D. Gill, W. Chen, O. King, and B. E. Little, “A universal biosensing platform based on optical micro-ring resonators,” Biosens. Bioelectron. 23(7), 939–944 (2008).
[CrossRef]

D. Dorfner, T. Zabel, T. Hürlimann, N. Hauke, L. Frandsen, U. Rant, G. Abstreiter, and J. Finley, “Photonic crystal nanostructures for optical biosensing applications,” Biosens. Bioelectron. 24(12), 3688–3692 (2009).
[CrossRef] [PubMed]

IEEE J. Sel. Top. Quantum Electron. (1)

M. Iqbal, M. A. Gleeson, B. Spaugh, F. Tybor, W. G. Gunn, M. Hochberg, T. Baehr-Jones, R. C. Bailey, and L. C. Gunn, “Label-Free Biosensor Arrays Based on Silicon Ring Resonators and High-Speed Optical Scanning Instrumentation,” IEEE J. Sel. Top. Quantum Electron. 16(3), 654–661 (2010).
[CrossRef]

J. Opt. A, Pure Appl. Opt. (1)

B. Sepúlveda, J. S. Río, M. Moreno, F. J. Blanco, K. Mayora, C. Domínguez, and L. M. Lechuga, “Optical biosensor microsystems based on the integration of highly sensitive Mach–Zehnder interferometer devices,” J. Opt. A, Pure Appl. Opt. 8(7), S561–S566 (2006).
[CrossRef]

J. Phys. Chem. Ref. Data (1)

P. Schiebener, J. Straub, J. M. H. Levelt Sengers, and J. S. Gallagher, “Refractive index of water and steam as function of wavelength, temperature and density,” J. Phys. Chem. Ref. Data 19(3), 677–717 (1990).
[CrossRef]

Lab Chip (1)

C. F. Carlborg, K. B. Gylfason, A. Kaźmierczak, F. Dortu, M. J. Bañuls Polo, A. Maquieira Catala, G. M. Kresbach, H. Sohlström, T. Moh, L. Vivien, J. Popplewell, G. Ronan, C. A. Barrios, G. Stemme, and W. van der Wijngaart, “A packaged optical slot-waveguide ring resonator sensor array for multiplex label-free assays in labs-on-chips,” Lab Chip 10(3), 281–290 (2010).
[CrossRef] [PubMed]

Meas. Sci. Technol. (1)

J. Rheims, J. Köser, and T. Wriedt, “Refractive-index measurements in the near-IR using an Abbe refractometer,” Meas. Sci. Technol. 8(6), 601–605 (1997).
[CrossRef]

Nat. Photonics (1)

T. F. Krauss, “Why do we need slow light?” Nat. Photonics 2(8), 448–450 (2008).
[CrossRef]

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Sens. Actuators A Phys. (1)

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This software can be encountered at http://camfr.sourceforge.net/

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Figures (8)

Fig. 1
Fig. 1

(Left) SEM image of the fabricated SOI planar photonic crystal waveguide, where a row of holes is removed in the Γ-K direction (W1-type). (Right) Spectrum of the PCW in the region of the band edge when having DIW as upper-cladding. Transmission fringes at the band edge are marked with dashed red line and enlarged in the inset.

Fig. 2
Fig. 2

(a) Schematic picture of the PCW with its access waveguides. The interface with the access waveguides is that of our fabricated PCW. The structural parameters of the PCW (i.e., lattice constant, hole radius and PCW length), and the transmission and reflection coefficients at each interface (t ij, r ij) are depicted. (b) Each signal contribution generated in the PCW because of the reflections in the interfaces with the access waveguides are combined at the output, being responsible of the appearance of FP oscillations in the transmission spectrum. Media 1 and 3 represent the access waveguides and medium 2 represents the PCW.

Fig. 3
Fig. 3

(a) Theoretical transmission (blue dotted line) and reflection coefficients (blue solid line), and propagation constant of the PCW (green solid line) calculated with CAMFR. (b) Transmission response of the 20μm-long PCW when the created FP cavity is considered (blue solid line). The transmission response when no cavity is considered (only the direct contribution propagating into the PCW) is also depicted (red dashed line). The inset shows a detail of the transmission band edge.

Fig. 4
Fig. 4

3D-FDTD simulations of the transmission spectrum of the 20μm-long PCW for two different uppercladdings: n 1 = 1.3173 (red line) and n 2 = 1.3200 (blue line). FP fringes near the band edge have been labelled from 1 to 6. The band edge fringes are slightly smoothed because of the stop time used to make the duration of the simulation reasonable.

Fig. 5
Fig. 5

Temporal evolution of the FP peak for the different ethanol-DIW dilutions flowed.

Fig. 6
Fig. 6

(a) Transmission spectra of the PCW at time positions marked in Fig. 5. (b) Blue circles depict the wavelength shift of the position of the maximum of the peak for the different ethanol-DIW dilutions. The linear fit of the data is depicted with dashed red line.

Fig. 7
Fig. 7

(a) Spectrum of the PCW in the region of the band edge when PBS 0.1x is flowed. (b) More detailed view of the transmission spectrum at the vicinities of the band edge. Transmission peaks in this region are marked with dashed red circles and their approximated wavelength positions are depicted.

Fig. 8
Fig. 8

Wavelength shift vs time for the different solutions flowed in the experiment. Each line (color and style identified in the legend) correspond to the relative shift of each tracked peak respect its initial wavelength position. The time instants when the flowed solution is switched are depicted in the figure.

Tables (2)

Tables Icon

Table 1 Wavelength shift and sensitivity for each FP fringe near the guided band edge for the 3D-FDTD simulations

Tables Icon

Table 2 Parameters characterizing the performance of the FP resonances used for the sensing experiments

Equations (1)

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n d i l u t i o n = 1.024 × ( % / 100 ) × n e t h a n o l + 1 × ( 1 % / 100 ) × n D I W ,

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