Abstract

We use diffuse optical tomography to quantitatively reconstruct images of complex phantoms with millimeter sized features located centimeters deep within a highly-scattering medium. A non-contact instrument was employed to collect large data sets consisting of greater than 107 source-detector pairs. Images were reconstructed using a fast image reconstruction algorithm based on an analytic solution to the inverse scattering problem for diffuse light.

© 2008 Optical Society of America

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2005

2004

V. A. Markel and J. C. Schotland, "Symmetries, inversion formulas and image reconstruction for optical tomography," Phys. Rev. E 70, 056,616 (2004).

2003

V. A. Markel, V. Mital, and J. C. Schotland, "The inverse problem in optical diffusion tomography. III. Inversion formulas and singular value decomposition," J. Opt. Soc. Am. A 20, 890-902 (2003).
[CrossRef]

G. Q. Yu, T. Durduran, D. Furuya, J. H. Greenberg, and A. G. Yodh, "Frequency-domain multiplexing system for in vivo diffuse light measurements of rapid cerebral hemodynamics," Appl. Opt. 42, 2931-2939 (2003).
[CrossRef]

Y. Xu, X. J. Gu, L. L. Fajardo, and H. B. Jiang, "In vivo breast imaging with diffuse optical tomography based on higher-order diffusion equations," Appl. Opt. 42, 3163-3169 (2003).
[CrossRef]

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, "Tomographic optical breast imaging guided by three-dimensional mammography," Appl. Opt. 42, 5181-5190 (2003).
[CrossRef]

R. Schulz, J. Ripoll, and V. Ntziachristos, "Noncontact optical tomography of turbid media," Opt. Lett. 28, 1701- 1703 (2003).
[CrossRef]

J. P. Culver, A. M. Siegel, J. J. Stott, and D. A. Boas, "Volumetric diffuse optical tomography of brain activity," Opt. Lett. 28, 2061-2063 (2003).
[CrossRef]

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

X. Intes, J. Ripoll, Y. Chen, S. Nioka, A. G. Yodh, and B. Chance, "In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green," Med. Phys. 30, 1039-1047 (2003).
[CrossRef]

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

J. C. Hebden, "Advances in optical imaging of the newborn infant brain," Psychophysiology 40, 501-510 (2003).
[CrossRef]

A. M. Siegel, J. P. Culver, J. B. Mandeville, and D. A. Boas, "Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation," Phys. Med. Biol. 48, 1391-1403 (2003).
[CrossRef]

2002

V. A. Markel and J. C. Schotland, "Effects of sampling and limited data in optical tomography," Appl. Phys. Lett. 81, 1180-1182 (2002).
[CrossRef]

G. Strangman, D. A. Boas, and J. P. Sutton, "Non-invasive neuroimaging using near-infrared light," Biol. Psychiatry 52, 679-693 (2002).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

V. A. Markel and J. C. Schotland, "The inverse problem in optical diffusion tomography. II. Inversion with boundary conditions," J. Opt. Soc. Am. A 19, 558-566 (2002).
[CrossRef]

2001

2000

D. J. Hawrysz and E. M. Sevick-Muraca, "Developments toward diagnostic breast cancer imaging using nearinfrared optical measurements and fluorescent contrast agants," Neoplasia 2, 388-417 (2000).
[CrossRef]

1999

S. R. Arridge, "Optical tomography in medical imaging," Inverse Problems 15, R41-R93 (1999).
[CrossRef]

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

M. C. W. van Rossum and T. M. Nieuwenhuizen, "Multiple scattering of classical waves: microscopy, mesoscopy and diffusion," Rev. Mod. Phys. 71, 313-371 (1999).
[CrossRef]

1997

1996

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

1995

A. Yodh and B. Chance, "Spectroscopy and imaging with diffuse light," Phys. Today 34-40 (1995).
[CrossRef]

R. Aronson, "Boundary conditions for diffuse light," J. Opt. Soc. Am. A 12, 2532-2539 (1995).

1994

D. A. Benaron, J. van Houten, D. C. Ho, S. D. Spilman, and D. K. Stevenson, "Imaging neonatal brain injury using light-based optical tomography," Pediatr. Res. 35, A378-A378 (1994).

Abdoulaev, G.

Aronson, R.

Arridge, S. R.

A. P. Gibson, J. C. Hebden, and S. R. Arridge, "Recent advances in diffuse optical imaging," Phys. Med. Biol. 50, R1-R43 (2005).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

S. R. Arridge, "Optical tomography in medical imaging," Inverse Problems 15, R41-R93 (1999).
[CrossRef]

Austin, T.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Barbour, R. L.

Benaron, D. A.

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

D. A. Benaron, J. van Houten, D. C. Ho, S. D. Spilman, and D. K. Stevenson, "Imaging neonatal brain injury using light-based optical tomography," Pediatr. Res. 35, A378-A378 (1994).

Bluestone, A. Y.

Boas, D. A.

J. P. Culver, A. M. Siegel, J. J. Stott, and D. A. Boas, "Volumetric diffuse optical tomography of brain activity," Opt. Lett. 28, 2061-2063 (2003).
[CrossRef]

A. Li, E. L. Miller, M. E. Kilmer, T. J. Brukilacchio, T. Chaves, J. Stott, Q. Zhang, T. Wu, M. Chorlton, R. H. Moore, D. B. Kopans, and D. A. Boas, "Tomographic optical breast imaging guided by three-dimensional mammography," Appl. Opt. 42, 5181-5190 (2003).
[CrossRef]

A. M. Siegel, J. P. Culver, J. B. Mandeville, and D. A. Boas, "Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation," Phys. Med. Biol. 48, 1391-1403 (2003).
[CrossRef]

G. Strangman, D. A. Boas, and J. P. Sutton, "Non-invasive neuroimaging using near-infrared light," Biol. Psychiatry 52, 679-693 (2002).
[CrossRef]

Brukilacchio, T. J.

Chance, B.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

X. Intes, J. Ripoll, Y. Chen, S. Nioka, A. G. Yodh, and B. Chance, "In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green," Med. Phys. 30, 1039-1047 (2003).
[CrossRef]

A. Yodh and B. Chance, "Spectroscopy and imaging with diffuse light," Phys. Today 34-40 (1995).
[CrossRef]

Chaves, T.

Chen, N. G.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Chen, Y.

X. Intes, J. Ripoll, Y. Chen, S. Nioka, A. G. Yodh, and B. Chance, "In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green," Med. Phys. 30, 1039-1047 (2003).
[CrossRef]

Cheong, W. F.

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

Choe, R.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

Chorlton, M.

Colak, S. B.

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

Culver, J. P.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

J. P. Culver, A. M. Siegel, J. J. Stott, and D. A. Boas, "Volumetric diffuse optical tomography of brain activity," Opt. Lett. 28, 2061-2063 (2003).
[CrossRef]

A. M. Siegel, J. P. Culver, J. B. Mandeville, and D. A. Boas, "Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation," Phys. Med. Biol. 48, 1391-1403 (2003).
[CrossRef]

Delpy, D. T.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Doyley, M. M.

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

Durduran, T.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

G. Q. Yu, T. Durduran, D. Furuya, J. H. Greenberg, and A. G. Yodh, "Frequency-domain multiplexing system for in vivo diffuse light measurements of rapid cerebral hemodynamics," Appl. Opt. 42, 2931-2939 (2003).
[CrossRef]

Everdell, N.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Fajardo, L. L.

Furuya, D.

Gibson, A.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Gibson, A. P.

A. P. Gibson, J. C. Hebden, and S. R. Arridge, "Recent advances in diffuse optical imaging," Phys. Med. Biol. 50, R1-R43 (2005).
[CrossRef]

Greenberg, J. H.

Gu, X. J.

Hawrysz, D. J.

D. J. Hawrysz and E. M. Sevick-Muraca, "Developments toward diagnostic breast cancer imaging using nearinfrared optical measurements and fluorescent contrast agants," Neoplasia 2, 388-417 (2000).
[CrossRef]

Hebden, J. C.

A. P. Gibson, J. C. Hebden, and S. R. Arridge, "Recent advances in diffuse optical imaging," Phys. Med. Biol. 50, R1-R43 (2005).
[CrossRef]

J. C. Hebden, "Advances in optical imaging of the newborn infant brain," Psychophysiology 40, 501-510 (2003).
[CrossRef]

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Hedge, P.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Hielscher, A. H.

Hillman, E. M. C.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Ho, D. C.

D. A. Benaron, J. van Houten, D. C. Ho, S. D. Spilman, and D. K. Stevenson, "Imaging neonatal brain injury using light-based optical tomography," Pediatr. Res. 35, A378-A378 (1994).

Holboke, M. J.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

Hooft, G. W.

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

Hoogenraad, J. H.

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

Huang, M. M.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Intes, X.

X. Intes, J. Ripoll, Y. Chen, S. Nioka, A. G. Yodh, and B. Chance, "In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green," Med. Phys. 30, 1039-1047 (2003).
[CrossRef]

Jagjivan, B.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Jiang, H. B.

Jiang, S. D.

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

Kane, M.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Kermit, E. L.

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

Kilmer, M. E.

Kopans, D. B.

Kuijpers, F. A.

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

Kurtzman, S. H.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Li, A.

Machold, T. R.

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

Mandeville, J. B.

A. M. Siegel, J. P. Culver, J. B. Mandeville, and D. A. Boas, "Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation," Phys. Med. Biol. 48, 1391-1403 (2003).
[CrossRef]

Markel, V. A.

McBride, T. O.

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

Meek, J. H.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Miller, E. L.

Mital, V.

Moore, R. H.

Nieuwenhuizen, T. M.

M. C. W. van Rossum and T. M. Nieuwenhuizen, "Multiple scattering of classical waves: microscopy, mesoscopy and diffusion," Rev. Mod. Phys. 71, 313-371 (1999).
[CrossRef]

Nioka, S.

X. Intes, J. Ripoll, Y. Chen, S. Nioka, A. G. Yodh, and B. Chance, "In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green," Med. Phys. 30, 1039-1047 (2003).
[CrossRef]

Ntziachristos, V.

G. Turner, G. Zacharakis, A. Soubret, J. Ripoll, and V. Ntziachristos, "Complete-angle projection diffuse optical tomography by use of early photons," Opt. Lett. 30, 409-411 (2005).
[CrossRef]

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

R. Schulz, J. Ripoll, and V. Ntziachristos, "Noncontact optical tomography of turbid media," Opt. Lett. 28, 1701- 1703 (2003).
[CrossRef]

Panasyuk, G. Y.

Paulsen, K. D.

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

Pogue, B. W.

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

Poplack, S. P.

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

Ripoll, J.

Schmitz, C. H.

Schotland, J. C.

Schulz, R.

Sevick-Muraca, E. M.

D. J. Hawrysz and E. M. Sevick-Muraca, "Developments toward diagnostic breast cancer imaging using nearinfrared optical measurements and fluorescent contrast agants," Neoplasia 2, 388-417 (2000).
[CrossRef]

Siegel, A. M.

J. P. Culver, A. M. Siegel, J. J. Stott, and D. A. Boas, "Volumetric diffuse optical tomography of brain activity," Opt. Lett. 28, 2061-2063 (2003).
[CrossRef]

A. M. Siegel, J. P. Culver, J. B. Mandeville, and D. A. Boas, "Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation," Phys. Med. Biol. 48, 1391-1403 (2003).
[CrossRef]

Slemp, A.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

Soubret, A.

Spilman, S. D.

D. A. Benaron, J. van Houten, D. C. Ho, S. D. Spilman, and D. K. Stevenson, "Imaging neonatal brain injury using light-based optical tomography," Pediatr. Res. 35, A378-A378 (1994).

Stevenson, D. K.

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

D. A. Benaron, J. van Houten, D. C. Ho, S. D. Spilman, and D. K. Stevenson, "Imaging neonatal brain injury using light-based optical tomography," Pediatr. Res. 35, A378-A378 (1994).

Stott, J.

Stott, J. J.

Strangman, G.

G. Strangman, D. A. Boas, and J. P. Sutton, "Non-invasive neuroimaging using near-infrared light," Biol. Psychiatry 52, 679-693 (2002).
[CrossRef]

Sutton, J. P.

G. Strangman, D. A. Boas, and J. P. Sutton, "Non-invasive neuroimaging using near-infrared light," Biol. Psychiatry 52, 679-693 (2002).
[CrossRef]

Turner, G.

van der Linden, E. S.

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

van der Mark, M. B.

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

van Houten, J.

D. A. Benaron, J. van Houten, D. C. Ho, S. D. Spilman, and D. K. Stevenson, "Imaging neonatal brain injury using light-based optical tomography," Pediatr. Res. 35, A378-A378 (1994).

van Houten, J. P.

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

van Rossum, M. C. W.

M. C. W. van Rossum and T. M. Nieuwenhuizen, "Multiple scattering of classical waves: microscopy, mesoscopy and diffusion," Rev. Mod. Phys. 71, 313-371 (1999).
[CrossRef]

Wang, Z.-M.

Wu, T.

Wyatt, J. S.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Xu, Y.

Yodh, A.

A. Yodh and B. Chance, "Spectroscopy and imaging with diffuse light," Phys. Today 34-40 (1995).
[CrossRef]

Yodh, A. G.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

X. Intes, J. Ripoll, Y. Chen, S. Nioka, A. G. Yodh, and B. Chance, "In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green," Med. Phys. 30, 1039-1047 (2003).
[CrossRef]

G. Q. Yu, T. Durduran, D. Furuya, J. H. Greenberg, and A. G. Yodh, "Frequency-domain multiplexing system for in vivo diffuse light measurements of rapid cerebral hemodynamics," Appl. Opt. 42, 2931-2939 (2003).
[CrossRef]

Yu, G. Q.

Yusof, R. M.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

Zacharakis, G.

Zarfos, K.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Zhang, Q.

Zhu, Q. I.

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

Zubkov, L.

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

Appl. Opt.

Appl. Phys. Lett.

V. A. Markel and J. C. Schotland, "Effects of sampling and limited data in optical tomography," Appl. Phys. Lett. 81, 1180-1182 (2002).
[CrossRef]

Biol. Psychiatry

G. Strangman, D. A. Boas, and J. P. Sutton, "Non-invasive neuroimaging using near-infrared light," Biol. Psychiatry 52, 679-693 (2002).
[CrossRef]

IEEE J. Sel. Top. Quantum Electron.

S. B. Colak, M. B. van der Mark, G. W. Hooft, J. H. Hoogenraad, E. S. van der Linden, and F. A. Kuijpers, "Clinical optical tomography and NIR spectroscopy for breast cancer detection," IEEE J. Sel. Top. Quantum Electron. 5, 1143-1158 (1999).

Inverse Problems

S. R. Arridge, "Optical tomography in medical imaging," Inverse Problems 15, R41-R93 (1999).
[CrossRef]

J. Electron. Imaging

S. D. Jiang, B. W. Pogue, T. O. McBride, M. M. Doyley, S. P. Poplack, and K. D. Paulsen, "Near-infrared breast tomography calibration with optoelastic tissue simulating phantoms," J. Electron. Imaging 12, 613-620 (2003).
[CrossRef]

J. Opt. Soc. Am. A

Med. Phys.

X. Intes, J. Ripoll, Y. Chen, S. Nioka, A. G. Yodh, and B. Chance, "In vivo continuous-wave optical breast imaging enhanced with Indocyanine Green," Med. Phys. 30, 1039-1047 (2003).
[CrossRef]

J. P. Culver, R. Choe, M. J. Holboke, L. Zubkov, T. Durduran, A. Slemp, V. Ntziachristos, B. Chance, and A. G. Yodh, "Three-dimensional diffuse optical tomography in the parallel plane transmission geometry: Evaluation of a hybrid frequency domain/continuous wave clinical system for breast imaging," Med. Phys. 30, 235-247 (2003).
[CrossRef]

Neoplasia

Q. I. Zhu, M. M. Huang, N. G. Chen, K. Zarfos, B. Jagjivan, M. Kane, P. Hedge, and S. H. Kurtzman, "Ultrasound-guided optical tomographic imaging of malignant and benign breast lesions: Initial clinical results of 19 cases," Neoplasia 5, 379-388 (2003).

D. J. Hawrysz and E. M. Sevick-Muraca, "Developments toward diagnostic breast cancer imaging using nearinfrared optical measurements and fluorescent contrast agants," Neoplasia 2, 388-417 (2000).
[CrossRef]

Opt. Express

Opt. Lett.

Pediatr. Res.

D. A. Benaron, J. van Houten, D. C. Ho, S. D. Spilman, and D. K. Stevenson, "Imaging neonatal brain injury using light-based optical tomography," Pediatr. Res. 35, A378-A378 (1994).

J. P. van Houten, W. F. Cheong, E. L. Kermit, T. R. Machold, D. K. Stevenson, and D. A. Benaron, "Clinical measurement of brain oxygenation and function using light-based optical tomography," Pediatr. Res. 39, 2273- 2273 (1996).

Phys. Med. Biol.

J. C. Hebden, A. Gibson, R. M. Yusof, N. Everdell, E. M. C. Hillman, D. T. Delpy, S. R. Arridge, T. Austin, J. H. Meek, and J. S. Wyatt, "Three-dimensional optical tomography of the premature infant brain," Phys. Med. Biol. 47, 4155-4166 (2002).
[CrossRef]

A. P. Gibson, J. C. Hebden, and S. R. Arridge, "Recent advances in diffuse optical imaging," Phys. Med. Biol. 50, R1-R43 (2005).
[CrossRef]

A. M. Siegel, J. P. Culver, J. B. Mandeville, and D. A. Boas, "Temporal comparison of functional brain imaging with diffuse optical tomography and fMRI during rat forepaw stimulation," Phys. Med. Biol. 48, 1391-1403 (2003).
[CrossRef]

Phys. Rev. E

V. A. Markel and J. C. Schotland, "Inverse scattering for the diffusion equation with general boundary conditions," Phys. Rev. E 64, R035,601 (2001).

V. A. Markel and J. C. Schotland, "Symmetries, inversion formulas and image reconstruction for optical tomography," Phys. Rev. E 70, 056,616 (2004).

Phys. Today

A. Yodh and B. Chance, "Spectroscopy and imaging with diffuse light," Phys. Today 34-40 (1995).
[CrossRef]

Psychophysiology

J. C. Hebden, "Advances in optical imaging of the newborn infant brain," Psychophysiology 40, 501-510 (2003).
[CrossRef]

Rev. Mod. Phys.

M. C. W. van Rossum and T. M. Nieuwenhuizen, "Multiple scattering of classical waves: microscopy, mesoscopy and diffusion," Rev. Mod. Phys. 71, 313-371 (1999).
[CrossRef]

Other

R. Choe, "Diffuse Optical Tomography and Spectroscopy of Breast Cancer and Fetal Brain," Ph.D. thesis, University of Pennsylvania (2005).

A. Ishimaru, Wave Propagation and Scattering in Random Media (IEEE Press, Piscataway, NJ, 1997).

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