Abstract

We describe results of theoretical and experimental investigations of artifacts that can arise in spectral-domain optical coherence tomography (SD-OCT) and optical frequency domain imaging (OFDI) as a result of sample or probe beam motion. While SD-OCT and OFDI are based on similar spectral interferometric principles, the specifics of motion effects are quite different because of distinct signal acquisition methods. These results provide an understanding of motion artifacts such as signal fading, spatial distortion and blurring, and emphasize the need for fast image acquisition in biomedical applications.

© 2004 Optical Society of America

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Am. J. Radiol. (1)

R. J. Alfidi, W. J. MacIntyre, and . R. Haaga, ???The effects of biological motion in CT resolution,??? Am. J. Radiol. 127, 11-15 (1976).

App. Phy. Lett. (1)

W. Eickhoff and R. Ulrich, ???Optical frequency domain reflectometry in single-mode fiber,??? App. Phy. Lett. 39, 693-695 (1981).

Appl. Opt. (1)

Circulation (1)

G. J. Tearney, H. Yabushita, S. L. Houser, H. T. Aretz, I. K. Jang, K. Schlendorf, C. R. Kauffman, M. Shishkov, E. F. Halpern, and B. E. Bouma, ???Quantification of macrophage content in atherosclerotic plaques by optical coherence tomography,??? Circulation 106, 113-119 (2003)

Electron. Lett. (1)

E. Brinkmeyer and R. Ulrich, ???High-resolution OCDR in dispersive waveguide,??? Electron. Lett. 26, 413-414 (1990).
[CrossRef]

Gastrointest. Endosc. (1)

M. V. Sivak Jr., K. Kobayashi, J. A. Izatt, A. M. Rollins, R. Ung-runyawee, A. Chak, R. C. K. Wong, G. A. Isenbert, and J. Willis, ???High-resolution Endoscopic imaging of the GI tract using optical coherence tomography,??? Gastrointest. Endosc. 51, 474-479 (2000).
[CrossRef]

Heart (1)

S.-M. Stengel, Y. Allemann, M. Zimmerli, E. Lipp, N. Kucher, P. Mohacsi, and C. Seiler, ???Doppler tissue imaging for assessing left ventricular diastolic dysfunction in heart transplant rejection,??? Heart 86, 432-437 (2001).
[CrossRef]

J. Biomed. Opt. (2)

J. M. Schmitt, S. H. Xiang, and K. M. Yung, ???Speckle in optical coherence tomography,??? J. Biomed. Opt. 4, 95-105 (1999).
[CrossRef]

G. Hausler and M. W. Lindner, ???Coherence radar and spectral radar - new tools for dermatological diagnosis,??? J. Biomed. Opt. 3, 21-31 (1998).
[CrossRef]

J. Opt. Soc. Am. A (1)

Jap. J. of App. Phys. (1)

T. Mitsui, ???Dynamic range of optical reflectometry with spectral interferometry,??? Jap. J. of App. Phys. 38, 6133-6137 (1999).

Med. Phys. (1)

M. L. Wood and R. M. Henkelman, ???NMR image artifact from periodic motion,??? Med. Phys. 12, 143-151 (1985).
[CrossRef]

Nat. Medicine (1)

J. G. Fujimoto, M. E. Brezinski, G. J. Tearney, S. A. Boppart, B. Bouma, M. R. Hee, J. F. Southern, and E. A. Swanson, ???Optical biopsy and imaging using optical coherence tomography,??? Nat. Medicine 1, 970-972 (1995).

Opt. Comm. (1)

A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. El-Zaiat, ???Measurements of intraocular distances by backscattering spectral interferometry,??? Opt. Comm. 117, 43-48 (1995).

Opt. Express (5)

R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, ???Performance of Fourier domain vs. time domain optical coherence tomography,??? Opt. Express 11, 889-894 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-8-889</a>

S. H. Yun, G. J. Tearney, J. F. de Boer, N. Iftimia, and B. E. Bouma, ???High-speed optical frequency-domain imaging,??? Opt. Express 11, 2953-2963 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-22-2953">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-22-2953</a>

S. H. Yun, G. J. Tearney, B. E. Bouma, B. H. Park, and J. F. de Boer, ???High-speed spectral domain optical coherence tomography at 1.3 µm wavelength,??? Opt. Express 11, 3598-3604 (2003), <a href=" http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-26-3598">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-26-3598</a>

N. Nassif, B Cense, B. H. Park, S. H. Yun, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. de Boer, ???In vivo high-resolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve,??? Opt. Express 12, 367-376 (2004), <a href=" http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-3-367">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-12-3-367</a>
[CrossRef]

M. A. Choma, M. V. Sarunic, C. Uang, and J. A. Izatt, ???Sensitivity advantage of swept source and Fourier domain optical coherence tomography,??? Opt. Express 11, 2183-2189 (2003), <a href="http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-18-2183">http://www.opticsexpress.org/abstract.cfm?URI=OPEX-11-18-2183</a>

Opt. Lett. (9)

N. Nassif, B. Cense, B. H. Park, S. H. Yun, T. C. Chen, B. E. Bouma, G. J. Tearney, and J. F. de Boer, ???In vivo human retinal imaging by ultrahigh-speed spectral domain optical coherence tomography,??? Opt. Lett. 29, 480-482 (2004).
[CrossRef]

M. Wojtkowski, T. Bajraszewski, P. Targowski, and A. Kowalczyk, ???Real time in vivo imaging by high-speed spectral optical coherence tomography,??? Opt. Lett. 28, 1745-1747 (2003).

S. H. Yun, C. Boudoux, G. J. Tearney, and B. E. Bouma, ???High-speed wavelength-swept semiconductor laser with a polygon-scanner-based wavelength filter,??? Opt. Lett. 28, 1981-1983 (2003).

J. F. de Boer, B. Cense, B.H. Park, M. C. Pierce, G. J. Tearney, and B. E. Bouma, ???Improved signal-to-noise ratio in spectral-domain compared with time-domain optical coherence tomography,??? Opt. Lett. 28, 2067-2069 (2003).

G. J. Tearney, S. A. Boppart, B. E. Bouma, M. E. Brezinski, N. J. Weissman, J. F. Southern, and J. G. Fujimoto, ???Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography," Opt. Lett. 21, 1-3 (1996).

R. C. Youngquist, S. Carr, and D. E. N. Davies, ???Optical coherence-domain reflectometry: A new optical evaluation technique,??? Opt. Lett., 12, 158-160 (1987).

E. A. Swanson, D. Huang, M. R. Hee, J. G. Fujimoto, C. P. Lin, and C. A. Puliafito, ???High-speed optical coherence domain reflectometry,??? Opt. Lett. 17, 151-153 (1992).

S. R. Chinn, E. Swanson, and J. G. Fujimoto, ???Optical coherence tomography using a frequency-tunable optical source,??? Opt. Lett. 22, 340-342 (1997).

B. Golubovic, B. E. Bouma, G. J. Tearney, and J. G. Fujimoto, ???Optical frequency-domain reflectometry using rapid wavelength tuning of a Cr4+:forsterite laser,??? Opt. Lett. 22, 1704-1706 (1997).

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W. G. Stinson, W. Chang, M. R. Hee, T. Flotte, K. Gregory, C. A. Puliafito, and J. G. Fujimoto, ???Optical coherence tomography,??? Science 254, 1178-1181 (1991).
[CrossRef]

Ultrasound in Med. & Biol. (1)

S. K. Nadkarni, D. R. Boughner, M. Drangova, and A. Fenster, ???In vitro simulation and quantification of temporal jitter artifacts in ECG-gated dynamic three-dimensional echocardiography,??? Ultrasound in Med. & Biol. 27, 211-222 (2001).
[CrossRef]

Other (2)

N. Bankman, Handbook of medical imaging (Academic Press, San Diego, 2000).

A. E. Siegman, Lasers (University Science Books, Mill Valley, 1986), Chap. 9.

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