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Parallel Fourier domain optical coherence tomography for in vivo measurement of the human eye

Branislav Grajciar, Michael Pircher, Adolf F. Fercher, and Rainer A. Leitgeb

Open Access Open Access

Abstract

A parallel Frequency Domain Optical Coherence Tomography (FD-OCT) system and - to the best of our knowledge- first in vivo tomograms obtained with such system are presented. A full tomogram of 256(x)×512(z) pixels covering a sample region of 8 mm×3,8 mm is recorded in only 1 ms. Since the transverse as well as the depth information is obtained in parallel, the structure is free of any motion artifacts. In order to study cross talk issues for parallel illumination the transversal resolution for a thermal light source is compared to that with an SLD.

©2005 Optical Society of America

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Figures (6)
Fig. 1.
Fig. 1. (a) The schematic of the Parallel FD OCT system. SLD - light source; L1 – collimator; CL-cylindrical lens, f=100 mm; L1–L5 - achromatic lens f=100 mm; NPBS - non-polarizing beam splitter 50:50; L6, L7 - achromatic lens f=310 mm; DG – diffraction grating; (b) Demonstration of line illumination (millimeter scale)

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Fig. 2.
Fig. 2. (a) Spectrum of the interferometer output after subtraction of the reference arm light: SLD (Red), Halogen Lamp (Blue), (b) Normalized coherence envelope after FFT of (a): SLD (Red), Halogen Lamp (Blue).

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Fig. 3.
Fig. 3. Diagrams of optical paths for two orthogonal planes of the anamorphic optical system. The abbreviations are the same as in Fig. 1.

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Fig. 4.
Fig. 4. (a) OCT tomogram of RTT- Group 1 – with SLD; (b) OCT tomogram of RTT- Group 2 with Halogen Lamp; (c) Cross section along the RTT surface for SLD, and in (d) for the Halogen Lamp.

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Fig. 5.
Fig. 5. Calculation of MPE for the eye

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Fig. 6.
Fig. 6. Human eye in vivo - Anterior chamber angle (a) without and (b) with correction. (c) Cornea and iris at a position close to iris rim; the scale bars correspond to 1mm vertically and 0.5mm horizontally.

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