Abstract

This paper describes a prototype of an acousto-optic video spectrometer module that can be linked with rigid lens-type and flexible optical-fiber medical endoscopes. Examples are given of the resulting spectral images, demonstrating the main quality of the developed layout—minimization of spatiospectral distortions. This allows the device to be used in problems of photoluminescence diagnosis in medical applications to rapidly obtain both spectral images and undistorted complete spectra of any point of an image of an internal organ. The possibilities and prospects of this approach are analyzed.

© 2013 Optical Society of America

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  1. V. V.  Tuchin, Optical Biomedical Diagnostics (Fizmatlit, Moscow, 2007).
  2. K.  Mudry, R.  Plonsey, J.  Bronzino, Biomedical Imaging (CRC Press, New York, 2003).
  3. A.  Goutzulis, D.  Rape, Design and Fabrication of Acousto-optic Devices (Dekker, New York, 1994).
  4. V.  Pustovoit, V.  Pozhar, “Collinear diffraction of light by sound waves in crystals: devices, applications, new ideas,” Photonics Optoelectron. 2, No. 2, 53 (1994).
  5. V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).
  6. N.  Gupta, J.  Ramella-Roman, “Detection of blood oxygen level by noninvasive passive spectral imaging of skin,” Proc. SPIE 6842, 68420C (2008).
    [CrossRef]
  7. I.  Kutuza, V.  Pozhar, V.  Pustovoit, “AOTF-based imaging spectrometers for research of small-size biological objects,” Proc. SPIE 5143, 165 (2003).
    [CrossRef]
  8. M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Fluorescence imaging spectroscopy utilising acousto-optic tuneable filters,” Proc. SPIE 5826, 185 (2005).
    [CrossRef]
  9. M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Use of acousto-optic tunable filter in fluorescence imaging endoscopy,” Proc. SPIE 5143, 305 (2003).
    [CrossRef]
  10. M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
    [CrossRef]
  11. M. M.  Mazur, V. É.  Pozhar, V. I.  Pustovo?t, V. N.  Shorin, “Double acousto-optical monochromators,” Usp. Sovrem. Radioélek. No. 10, 19 (2006).
  12. A. S.  Machikhin, V. É.  Pozhar, “Image distortions accompanying transmission through double acousto-optic monochromators,” Élektromag. Volny Élek. Sistemy 14, No. 11, 63 (2009).
  13. A. S.  Machikhin, V. I.  Batshev, A. V.  Perchik, “Calculating optical systems for matching tunable acousto-optic filters and eyepieces of observational devices,” in Collection of the Papers of the Ninth International Conference on Applied Optics, St. Petersburg, 2012, vol. 1, pp. 132–135.
  14. V.  Pozhar, A.  Machihin, “Image aberrations caused by light diffraction via ultrasonic waves in uniaxial crystals.,” Appl. Opt. 51, 4513 (2012).
    [CrossRef]
  15. V.  Voloshinov, K.  Yushkov, B.  Linde, “Improvement in performance of a TeO2 acousto-optic imaging spectrometer,” J. Opt. A 9, 341 (2007).
    [CrossRef]

2012

2009

A. S.  Machikhin, V. É.  Pozhar, “Image distortions accompanying transmission through double acousto-optic monochromators,” Élektromag. Volny Élek. Sistemy 14, No. 11, 63 (2009).

2008

V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).

N.  Gupta, J.  Ramella-Roman, “Detection of blood oxygen level by noninvasive passive spectral imaging of skin,” Proc. SPIE 6842, 68420C (2008).
[CrossRef]

2007

V.  Voloshinov, K.  Yushkov, B.  Linde, “Improvement in performance of a TeO2 acousto-optic imaging spectrometer,” J. Opt. A 9, 341 (2007).
[CrossRef]

2006

M. M.  Mazur, V. É.  Pozhar, V. I.  Pustovo?t, V. N.  Shorin, “Double acousto-optical monochromators,” Usp. Sovrem. Radioélek. No. 10, 19 (2006).

2005

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Fluorescence imaging spectroscopy utilising acousto-optic tuneable filters,” Proc. SPIE 5826, 185 (2005).
[CrossRef]

2003

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Use of acousto-optic tunable filter in fluorescence imaging endoscopy,” Proc. SPIE 5143, 305 (2003).
[CrossRef]

I.  Kutuza, V.  Pozhar, V.  Pustovoit, “AOTF-based imaging spectrometers for research of small-size biological objects,” Proc. SPIE 5143, 165 (2003).
[CrossRef]

1994

V.  Pustovoit, V.  Pozhar, “Collinear diffraction of light by sound waves in crystals: devices, applications, new ideas,” Photonics Optoelectron. 2, No. 2, 53 (1994).

Aprahamian, M.

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Fluorescence imaging spectroscopy utilising acousto-optic tuneable filters,” Proc. SPIE 5826, 185 (2005).
[CrossRef]

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Use of acousto-optic tunable filter in fluorescence imaging endoscopy,” Proc. SPIE 5143, 305 (2003).
[CrossRef]

Batshev, V. I.

A. S.  Machikhin, V. I.  Batshev, A. V.  Perchik, “Calculating optical systems for matching tunable acousto-optic filters and eyepieces of observational devices,” in Collection of the Papers of the Ninth International Conference on Applied Optics, St. Petersburg, 2012, vol. 1, pp. 132–135.

Boritko, S. V.

V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).

Bouhifd, M.

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Fluorescence imaging spectroscopy utilising acousto-optic tuneable filters,” Proc. SPIE 5826, 185 (2005).
[CrossRef]

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Use of acousto-optic tunable filter in fluorescence imaging endoscopy,” Proc. SPIE 5143, 305 (2003).
[CrossRef]

Bronzino, J.

K.  Mudry, R.  Plonsey, J.  Bronzino, Biomedical Imaging (CRC Press, New York, 2003).

DeNovo, R.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Gon Song, S.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Goutzulis, A.

A.  Goutzulis, D.  Rape, Design and Fabrication of Acousto-optic Devices (Dekker, New York, 1994).

Gupta, N.

N.  Gupta, J.  Ramella-Roman, “Detection of blood oxygen level by noninvasive passive spectral imaging of skin,” Proc. SPIE 6842, 68420C (2008).
[CrossRef]

Kutuza, I.

I.  Kutuza, V.  Pozhar, V.  Pustovoit, “AOTF-based imaging spectrometers for research of small-size biological objects,” Proc. SPIE 5143, 165 (2003).
[CrossRef]

Kutuza, I. B.

V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).

Linde, B.

V.  Voloshinov, K.  Yushkov, B.  Linde, “Improvement in performance of a TeO2 acousto-optic imaging spectrometer,” J. Opt. A 9, 341 (2007).
[CrossRef]

Machihin, A.

Machikhin, A. S.

A. S.  Machikhin, V. É.  Pozhar, “Image distortions accompanying transmission through double acousto-optic monochromators,” Élektromag. Volny Élek. Sistemy 14, No. 11, 63 (2009).

A. S.  Machikhin, V. I.  Batshev, A. V.  Perchik, “Calculating optical systems for matching tunable acousto-optic filters and eyepieces of observational devices,” in Collection of the Papers of the Ninth International Conference on Applied Optics, St. Petersburg, 2012, vol. 1, pp. 132–135.

Martin, M.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Mazur, M. M.

M. M.  Mazur, V. É.  Pozhar, V. I.  Pustovo?t, V. N.  Shorin, “Double acousto-optical monochromators,” Usp. Sovrem. Radioélek. No. 10, 19 (2006).

Moyers, T.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Mudry, K.

K.  Mudry, R.  Plonsey, J.  Bronzino, Biomedical Imaging (CRC Press, New York, 2003).

Overholt, B.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Panjehpour, M.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Perchik, A. V.

V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).

A. S.  Machikhin, V. I.  Batshev, A. V.  Perchik, “Calculating optical systems for matching tunable acousto-optic filters and eyepieces of observational devices,” in Collection of the Papers of the Ninth International Conference on Applied Optics, St. Petersburg, 2012, vol. 1, pp. 132–135.

Phan, M.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Plonsey, R.

K.  Mudry, R.  Plonsey, J.  Bronzino, Biomedical Imaging (CRC Press, New York, 2003).

Pozhar, V.

V.  Pozhar, A.  Machihin, “Image aberrations caused by light diffraction via ultrasonic waves in uniaxial crystals.,” Appl. Opt. 51, 4513 (2012).
[CrossRef]

I.  Kutuza, V.  Pozhar, V.  Pustovoit, “AOTF-based imaging spectrometers for research of small-size biological objects,” Proc. SPIE 5143, 165 (2003).
[CrossRef]

V.  Pustovoit, V.  Pozhar, “Collinear diffraction of light by sound waves in crystals: devices, applications, new ideas,” Photonics Optoelectron. 2, No. 2, 53 (1994).

Pozhar, V. É.

A. S.  Machikhin, V. É.  Pozhar, “Image distortions accompanying transmission through double acousto-optic monochromators,” Élektromag. Volny Élek. Sistemy 14, No. 11, 63 (2009).

V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).

M. M.  Mazur, V. É.  Pozhar, V. I.  Pustovo?t, V. N.  Shorin, “Double acousto-optical monochromators,” Usp. Sovrem. Radioélek. No. 10, 19 (2006).

Pustovoit, V.

I.  Kutuza, V.  Pozhar, V.  Pustovoit, “AOTF-based imaging spectrometers for research of small-size biological objects,” Proc. SPIE 5143, 165 (2003).
[CrossRef]

V.  Pustovoit, V.  Pozhar, “Collinear diffraction of light by sound waves in crystals: devices, applications, new ideas,” Photonics Optoelectron. 2, No. 2, 53 (1994).

Pustovoit, V. I.

M. M.  Mazur, V. É.  Pozhar, V. I.  Pustovo?t, V. N.  Shorin, “Double acousto-optical monochromators,” Usp. Sovrem. Radioélek. No. 10, 19 (2006).

Ramella-Roman, J.

N.  Gupta, J.  Ramella-Roman, “Detection of blood oxygen level by noninvasive passive spectral imaging of skin,” Proc. SPIE 6842, 68420C (2008).
[CrossRef]

Rape, D.

A.  Goutzulis, D.  Rape, Design and Fabrication of Acousto-optic Devices (Dekker, New York, 1994).

Shorin, V. N.

V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).

M. M.  Mazur, V. É.  Pozhar, V. I.  Pustovo?t, V. N.  Shorin, “Double acousto-optical monochromators,” Usp. Sovrem. Radioélek. No. 10, 19 (2006).

Tuchin, V. V.

V. V.  Tuchin, Optical Biomedical Diagnostics (Fizmatlit, Moscow, 2007).

Vo-Dohn, T.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Voloshinov, V.

V.  Voloshinov, K.  Yushkov, B.  Linde, “Improvement in performance of a TeO2 acousto-optic imaging spectrometer,” J. Opt. A 9, 341 (2007).
[CrossRef]

Wabuyele, M.

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Whelan, M.

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Fluorescence imaging spectroscopy utilising acousto-optic tuneable filters,” Proc. SPIE 5826, 185 (2005).
[CrossRef]

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Use of acousto-optic tunable filter in fluorescence imaging endoscopy,” Proc. SPIE 5143, 305 (2003).
[CrossRef]

Yushkov, K.

V.  Voloshinov, K.  Yushkov, B.  Linde, “Improvement in performance of a TeO2 acousto-optic imaging spectrometer,” J. Opt. A 9, 341 (2007).
[CrossRef]

Al’manakh Klinich. Med.

V. É.  Pozhar, S. V.  Boritko, I. B.  Kutuza, A. V.  Perchik, V. N.  Shorin, “Stand for developing methods and facilities of fluorescence diagnosis of cancer,” Al’manakh Klinich. Med. 17, 123 (2008).

Appl. Opt.

Élektromag. Volny Élek. Sistemy

A. S.  Machikhin, V. É.  Pozhar, “Image distortions accompanying transmission through double acousto-optic monochromators,” Élektromag. Volny Élek. Sistemy 14, No. 11, 63 (2009).

J. Opt. A

V.  Voloshinov, K.  Yushkov, B.  Linde, “Improvement in performance of a TeO2 acousto-optic imaging spectrometer,” J. Opt. A 9, 341 (2007).
[CrossRef]

Photonics Optoelectron.

V.  Pustovoit, V.  Pozhar, “Collinear diffraction of light by sound waves in crystals: devices, applications, new ideas,” Photonics Optoelectron. 2, No. 2, 53 (1994).

Proc. SPIE

N.  Gupta, J.  Ramella-Roman, “Detection of blood oxygen level by noninvasive passive spectral imaging of skin,” Proc. SPIE 6842, 68420C (2008).
[CrossRef]

I.  Kutuza, V.  Pozhar, V.  Pustovoit, “AOTF-based imaging spectrometers for research of small-size biological objects,” Proc. SPIE 5143, 165 (2003).
[CrossRef]

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Fluorescence imaging spectroscopy utilising acousto-optic tuneable filters,” Proc. SPIE 5826, 185 (2005).
[CrossRef]

M.  Bouhifd, M.  Whelan, M.  Aprahamian, “Use of acousto-optic tunable filter in fluorescence imaging endoscopy,” Proc. SPIE 5143, 305 (2003).
[CrossRef]

M.  Martin, M.  Wabuyele, M.  Panjehpour, M.  Phan, B.  Overholt, R.  DeNovo, T.  Moyers, S.  Gon Song, T.  Vo-Dohn, “Dual modality fluorescence and reflectance hyperspectral imaging: principle and applications,” Proc. SPIE 5692, 133 (2005).
[CrossRef]

Usp. Sovrem. Radioélek.

M. M.  Mazur, V. É.  Pozhar, V. I.  Pustovo?t, V. N.  Shorin, “Double acousto-optical monochromators,” Usp. Sovrem. Radioélek. No. 10, 19 (2006).

Other

A. S.  Machikhin, V. I.  Batshev, A. V.  Perchik, “Calculating optical systems for matching tunable acousto-optic filters and eyepieces of observational devices,” in Collection of the Papers of the Ninth International Conference on Applied Optics, St. Petersburg, 2012, vol. 1, pp. 132–135.

V. V.  Tuchin, Optical Biomedical Diagnostics (Fizmatlit, Moscow, 2007).

K.  Mudry, R.  Plonsey, J.  Bronzino, Biomedical Imaging (CRC Press, New York, 2003).

A.  Goutzulis, D.  Rape, Design and Fabrication of Acousto-optic Devices (Dekker, New York, 1994).

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