Abstract

New methods have been developed for noninvasive monitoring of pathological processes in a living organism by means of terahertz spectroscopy and visualization using contrast agents based on magnetic nanoparticles. The nanoparticles must possess good magnetic characteristics, must be nontoxic and stable against aggregation, and must exhibit chemical stability; therefore, they are enclosed in a biologically inert shell. This paper discusses the spectral features of iron oxide nanoparticles in a biologically inert shell consisting of silicon dioxide and nanoparticles of iron oxide and hydroxide in the terahertz frequency range. It is shown that the crystalline phase of iron oxide can be identified for both types of nanoparticles by means of terahertz spectroscopy.

© 2017 Optical Society of America

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