Abstract

We report a novel extension of 840 nm wavelength- based spectral domain optical tomography to in vivo/real-time human middle ear diagnosis. The system was designed to access the middle ear region with a specifically dedicated handheld probe. The real-time displaying feature was mandatory for in vivo imaging human subject with the handheld probe, and the system could provide about 20 frames per second for 2048 pixels by 1000 A-scans without using any graphics process units under the Labview platform. The inner ear structure of a healthy male volunteer was imaged with the developed system with the axial and lateral resolutions of 15 µm and 30 µm, respectively. The application of the OCT technology to early diagnose otitis media(OM) is very promising and could be another extensive branch in the OCT field because it provides the depth resolved image including tympanic membrane (TM) and structures below TM whereas the conventional otoscope technique only gives asurface image of the TM.

© 2011 Optical Society of Korea

PDF Article

References

  • View by:
  • |
  • |

  1. D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W.G. Stinson, W. Chang, M. Hee, T. Flotte, K. Gregory, C. A.Puliafito, and J. G. Fujimoto, “Optical coherence tomography,”Science 254, 1178-1181 (1991).
    [CrossRef]
  2. B. E. Bouma and G. J. Tearney, Handbook of Optical CoherenceTomography (Marcel Dekker Inc., New York, USA, 2002).
  3. A. F. Fercher, W. Drexler, C. K. Hitzenberger, and T. Lasser,“Optical coherence tomography-principles and applications,”Rep. Prog. Phys. 66, 239-303 (2003).
    [CrossRef]
  4. J. M. Schmitt, “Optical coherence tomography(OCT): areview,” IEEE J. Select. Topics Quantum Electron. 5, 1205-1215(2007).
  5. J. Kim, B.-S. Sohn, and T. E. Milner, “Real-time retinal imagingwith a parallel optical coherence tomography using a CMOSsmart array detector,” J. Korean Phys. Soc. 51, 1787-1791 (2007).
    [CrossRef]
  6. Y. K. Tao, M. Zhao, and J. A. Izatt, “High-speed complexconjugate resolved retinal spectral domain optical coherencetomography using sinusoidal phase modulation,” Opt. Lett.32, 2918-2920 (2007).
    [CrossRef]
  7. Y. Yasuno, V. D. Madjarova, S. Makita, M. Akiba, A.Morosawa, C. Chong, T. Sakai, K.-P. Chan, M. Itoh, andT. Yatagai, “Three-dimensional and high-speed swept-sourceoptical coherence tomography for in vivo investigation ofhuman anterior eye segments,” Opt. Express 13, 10652-10664(2005).
    [CrossRef]
  8. M. Jeon, U. Jung, J.-W. Song, J. Kim, J. Oh, J. Eom, C.-S. Kim,and Y.-H. Park, “Frequency swept laser at 1300 nm using awavelength scanning filter based on a rotating slit disk,” J.Opt. Soc. Korea 13, 330-334 (2009).
    [CrossRef]
  9. C. T. Nguyen, H. Tu, E. J. Chaney, C. N. Stewart, and S.A. Boppart, “Non-invasive optical interferometry for theassessment of biofilm growth in the middle ear,” BiomedicalOpt. Express 1, 1104-1116 (2010).
    [CrossRef]

2010 (1)

C. T. Nguyen, H. Tu, E. J. Chaney, C. N. Stewart, and S.A. Boppart, “Non-invasive optical interferometry for theassessment of biofilm growth in the middle ear,” BiomedicalOpt. Express 1, 1104-1116 (2010).
[CrossRef]

2009 (1)

M. Jeon, U. Jung, J.-W. Song, J. Kim, J. Oh, J. Eom, C.-S. Kim,and Y.-H. Park, “Frequency swept laser at 1300 nm using awavelength scanning filter based on a rotating slit disk,” J.Opt. Soc. Korea 13, 330-334 (2009).
[CrossRef]

2007 (3)

J. M. Schmitt, “Optical coherence tomography(OCT): areview,” IEEE J. Select. Topics Quantum Electron. 5, 1205-1215(2007).

J. Kim, B.-S. Sohn, and T. E. Milner, “Real-time retinal imagingwith a parallel optical coherence tomography using a CMOSsmart array detector,” J. Korean Phys. Soc. 51, 1787-1791 (2007).
[CrossRef]

Y. K. Tao, M. Zhao, and J. A. Izatt, “High-speed complexconjugate resolved retinal spectral domain optical coherencetomography using sinusoidal phase modulation,” Opt. Lett.32, 2918-2920 (2007).
[CrossRef]

2005 (1)

2003 (1)

A. F. Fercher, W. Drexler, C. K. Hitzenberger, and T. Lasser,“Optical coherence tomography-principles and applications,”Rep. Prog. Phys. 66, 239-303 (2003).
[CrossRef]

2002 (1)

B. E. Bouma and G. J. Tearney, Handbook of Optical CoherenceTomography (Marcel Dekker Inc., New York, USA, 2002).

1991 (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W.G. Stinson, W. Chang, M. Hee, T. Flotte, K. Gregory, C. A.Puliafito, and J. G. Fujimoto, “Optical coherence tomography,”Science 254, 1178-1181 (1991).
[CrossRef]

Biomedical Opt. Express (1)

C. T. Nguyen, H. Tu, E. J. Chaney, C. N. Stewart, and S.A. Boppart, “Non-invasive optical interferometry for theassessment of biofilm growth in the middle ear,” BiomedicalOpt. Express 1, 1104-1116 (2010).
[CrossRef]

IEEE J. Select. Topics Quantum Electron. (1)

J. M. Schmitt, “Optical coherence tomography(OCT): areview,” IEEE J. Select. Topics Quantum Electron. 5, 1205-1215(2007).

Journal of the Korean Physical Society (1)

J. Kim, B.-S. Sohn, and T. E. Milner, “Real-time retinal imagingwith a parallel optical coherence tomography using a CMOSsmart array detector,” J. Korean Phys. Soc. 51, 1787-1791 (2007).
[CrossRef]

Journal of the Optical Society of Korea (1)

M. Jeon, U. Jung, J.-W. Song, J. Kim, J. Oh, J. Eom, C.-S. Kim,and Y.-H. Park, “Frequency swept laser at 1300 nm using awavelength scanning filter based on a rotating slit disk,” J.Opt. Soc. Korea 13, 330-334 (2009).
[CrossRef]

Opt. Express (1)

Opt. Lett. (1)

Rep. Prog. Phys. (1)

A. F. Fercher, W. Drexler, C. K. Hitzenberger, and T. Lasser,“Optical coherence tomography-principles and applications,”Rep. Prog. Phys. 66, 239-303 (2003).
[CrossRef]

Science (1)

D. Huang, E. A. Swanson, C. P. Lin, J. S. Schuman, W.G. Stinson, W. Chang, M. Hee, T. Flotte, K. Gregory, C. A.Puliafito, and J. G. Fujimoto, “Optical coherence tomography,”Science 254, 1178-1181 (1991).
[CrossRef]

Other (1)

B. E. Bouma and G. J. Tearney, Handbook of Optical CoherenceTomography (Marcel Dekker Inc., New York, USA, 2002).

Cited By

OSA participates in CrossRef's Cited-By Linking service. Citing articles from OSA journals and other participating publishers are listed here.