Abstract

Blood pressure was predicted from photoplethysmography (PPG). To obtain PPG, backscattered light from a fingertip was measured and its waveform was analyzed. Systolic upstroke time and diastolic time in the pulse waveform were used as parameters to predict blood pressure. The experiment was carried out with five subjects on five different days. The systolic upstroke time had a correlation coefficient of -0.605 with respect to systolic blood pressure and the diastolic time had a correlation coefficients of -0.764 for diastolic pressure. This PPG method does not require an air-cuff installation on the arm and can predict blood pressure continuously. This simple LED/photo detector setup can be a good candidate for nonconstrained monitoring of blood pressure variations.

© 2006 Optical Society of Korea

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  1. K. J. Fleckenstein, "The Mosso plethysmograph in 19th century physiology," Medical Instrumentation, vol. 18, pp. 330-331, 1984
  2. J. Spiguilis, "Optical noninvasive monitoring of skin blood pulsations," Applied Optics, vol. 44, no. 10, pp. 1850-1857, 2005
    [CrossRef]
  3. J.G. Webster ed., Design of Pulse Oximeters (Institute of Physics Publishing, Bristol and Philadelphia, 1997), pp. 13-39
  4. S. Yasuda, S. Itoh, K. Isobe, M. Yonetani, H. Nakamura, M. Nakamura, Y. Yamauchi, and A. Yamanishi, "New transcutaneous jaundice device with two optical paths," J. Perinat. Med., vol. 31, pp. 81-88, 2003
    [CrossRef]
  5. G. Yoon and K-J Jeon, "Noninvasive hematocrit monitoring based on parameter-optimization of a LED finger probe," Journal of the Optical Society of Korea, vol. 9, no. 3., pp. 107-110, 2005
  6. J. Allen and A. Murray, "Age-related changes in peripheral pulse timing characteristics at the ears, fingers and toes," J. Human Hypertension, vol. 16, pp. 711-717, 2002
    [CrossRef]
  7. C. Choi, K-S Soh, S.M. Lee, and G. Yoon, "Propagation of light along an Acupuncture meridian," Journal of the Optical Society of Korea, vol. 7, no. 4, pp. 245-248, 2003
    [CrossRef]
  8. Y. Chen, L. Li, C. Hershler, and R.P. Dill, "Continuous non-invasive blood pressure monitoring method and apparatus," US patent, 6,893,401 B2, 2005
  9. J.G. Webster ed., Medical Instrumentation, 3rd edition (John Wiley & Sons, New York), PP. 324-328, 1998
  10. J. Bai, Y. Zhang, D. Shen, L. Wen C. Ding, Z. Cui, F. Tian, B. Yu, B. Dai, and J. Zhang, "A portable ECG and blood pressure telemonitoring system," IEEE Eng. In Med. Bio., pp. 63-70, July/August, 1999
    [CrossRef]
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  12. X.F. Teng and Y. T. Zhang, "Continuous and noninvasive estimation of arterial blood pressure using a photoplethysmographic approach," Pro. 25 Ann. IEEE EMBS, pp. 3153-3156, 2003
  13. D. Barschdorff and M. Erig, "Continuous blood pressure monitoring during stress ECG," Biomed. Tech. (Berl), vol. 43, pp. 34-39, 1998
    [CrossRef]
  14. J. E. Naschitz, S. Bezobchuk, R. Priselac, S. Sundick, D. Dreyfuss, I. Khorshidi, A. Karidis, H. Manor, M. Nagar, E.R. Peck, S. Peck, S. Storch, I. Rosner, and L. Gaitini, "Pulse transit time by R-wave-gated infrared photoplethysmography: review of the literature and personal experience," J. Clin. Monit. aad Comput., vol. 18, pp. 333-342, 2004
    [CrossRef]
  15. J.D. Curb, D.R. Labarthe, S.P. Cooper, G. R. Cutter, and C.M. Hawkins, "Training and certification of blood pressure observers," Hypertension, vol. 5, pp. 610-614, 1983
  16. H.A. Martens and P. Dardenne, "Validation and verifi-cation of regression in small data sets," Chemometrics intelligent laboratory Sys., vol. 44, pp. 99-122, 1998
    [CrossRef]
  17. M. Stone, "An asymptotic equivalence of choice of model by cross-validation and akaike"s criterion," J. R. Stat. Soc. B, vol. 38, pp. 44-47, 1977

2005 (3)

J. Spiguilis, "Optical noninvasive monitoring of skin blood pulsations," Applied Optics, vol. 44, no. 10, pp. 1850-1857, 2005
[CrossRef]

G. Yoon and K-J Jeon, "Noninvasive hematocrit monitoring based on parameter-optimization of a LED finger probe," Journal of the Optical Society of Korea, vol. 9, no. 3., pp. 107-110, 2005

Y. Chen, L. Li, C. Hershler, and R.P. Dill, "Continuous non-invasive blood pressure monitoring method and apparatus," US patent, 6,893,401 B2, 2005

2004 (1)

J. E. Naschitz, S. Bezobchuk, R. Priselac, S. Sundick, D. Dreyfuss, I. Khorshidi, A. Karidis, H. Manor, M. Nagar, E.R. Peck, S. Peck, S. Storch, I. Rosner, and L. Gaitini, "Pulse transit time by R-wave-gated infrared photoplethysmography: review of the literature and personal experience," J. Clin. Monit. aad Comput., vol. 18, pp. 333-342, 2004
[CrossRef]

2003 (3)

X.F. Teng and Y. T. Zhang, "Continuous and noninvasive estimation of arterial blood pressure using a photoplethysmographic approach," Pro. 25 Ann. IEEE EMBS, pp. 3153-3156, 2003

S. Yasuda, S. Itoh, K. Isobe, M. Yonetani, H. Nakamura, M. Nakamura, Y. Yamauchi, and A. Yamanishi, "New transcutaneous jaundice device with two optical paths," J. Perinat. Med., vol. 31, pp. 81-88, 2003
[CrossRef]

C. Choi, K-S Soh, S.M. Lee, and G. Yoon, "Propagation of light along an Acupuncture meridian," Journal of the Optical Society of Korea, vol. 7, no. 4, pp. 245-248, 2003
[CrossRef]

2002 (1)

J. Allen and A. Murray, "Age-related changes in peripheral pulse timing characteristics at the ears, fingers and toes," J. Human Hypertension, vol. 16, pp. 711-717, 2002
[CrossRef]

1999 (1)

J. Bai, Y. Zhang, D. Shen, L. Wen C. Ding, Z. Cui, F. Tian, B. Yu, B. Dai, and J. Zhang, "A portable ECG and blood pressure telemonitoring system," IEEE Eng. In Med. Bio., pp. 63-70, July/August, 1999
[CrossRef]

1998 (4)

H. Hosaka, H. Sakata, Y. Sugo, T. Sohma, and H. Kasuya, "Pulse-wave propagation time basis blood pressure monitor," US patent, 5,649,543, 1998

D. Barschdorff and M. Erig, "Continuous blood pressure monitoring during stress ECG," Biomed. Tech. (Berl), vol. 43, pp. 34-39, 1998
[CrossRef]

H.A. Martens and P. Dardenne, "Validation and verifi-cation of regression in small data sets," Chemometrics intelligent laboratory Sys., vol. 44, pp. 99-122, 1998
[CrossRef]

J.G. Webster ed., Medical Instrumentation, 3rd edition (John Wiley & Sons, New York), PP. 324-328, 1998

1997 (1)

J.G. Webster ed., Design of Pulse Oximeters (Institute of Physics Publishing, Bristol and Philadelphia, 1997), pp. 13-39

1984 (1)

K. J. Fleckenstein, "The Mosso plethysmograph in 19th century physiology," Medical Instrumentation, vol. 18, pp. 330-331, 1984

1983 (1)

J.D. Curb, D.R. Labarthe, S.P. Cooper, G. R. Cutter, and C.M. Hawkins, "Training and certification of blood pressure observers," Hypertension, vol. 5, pp. 610-614, 1983

1977 (1)

M. Stone, "An asymptotic equivalence of choice of model by cross-validation and akaike"s criterion," J. R. Stat. Soc. B, vol. 38, pp. 44-47, 1977

Applied Optics (1)

J. Spiguilis, "Optical noninvasive monitoring of skin blood pulsations," Applied Optics, vol. 44, no. 10, pp. 1850-1857, 2005
[CrossRef]

Biomedizinische Technik;Biomedical Engineering (1)

D. Barschdorff and M. Erig, "Continuous blood pressure monitoring during stress ECG," Biomed. Tech. (Berl), vol. 43, pp. 34-39, 1998
[CrossRef]

Chemometrics and Intelligent Laboratory Systems (1)

H.A. Martens and P. Dardenne, "Validation and verifi-cation of regression in small data sets," Chemometrics intelligent laboratory Sys., vol. 44, pp. 99-122, 1998
[CrossRef]

Hypertension (1)

J.D. Curb, D.R. Labarthe, S.P. Cooper, G. R. Cutter, and C.M. Hawkins, "Training and certification of blood pressure observers," Hypertension, vol. 5, pp. 610-614, 1983

IEEE Engineering in Medicine and Biology Magazine (1)

J. Bai, Y. Zhang, D. Shen, L. Wen C. Ding, Z. Cui, F. Tian, B. Yu, B. Dai, and J. Zhang, "A portable ECG and blood pressure telemonitoring system," IEEE Eng. In Med. Bio., pp. 63-70, July/August, 1999
[CrossRef]

Journal of Clinical Monitoring and Computing (1)

J. E. Naschitz, S. Bezobchuk, R. Priselac, S. Sundick, D. Dreyfuss, I. Khorshidi, A. Karidis, H. Manor, M. Nagar, E.R. Peck, S. Peck, S. Storch, I. Rosner, and L. Gaitini, "Pulse transit time by R-wave-gated infrared photoplethysmography: review of the literature and personal experience," J. Clin. Monit. aad Comput., vol. 18, pp. 333-342, 2004
[CrossRef]

Journal of Human Hypertension (1)

J. Allen and A. Murray, "Age-related changes in peripheral pulse timing characteristics at the ears, fingers and toes," J. Human Hypertension, vol. 16, pp. 711-717, 2002
[CrossRef]

Journal of Perinatal Medicine (1)

S. Yasuda, S. Itoh, K. Isobe, M. Yonetani, H. Nakamura, M. Nakamura, Y. Yamauchi, and A. Yamanishi, "New transcutaneous jaundice device with two optical paths," J. Perinat. Med., vol. 31, pp. 81-88, 2003
[CrossRef]

Journal of the Optical Society of Korea (2)

G. Yoon and K-J Jeon, "Noninvasive hematocrit monitoring based on parameter-optimization of a LED finger probe," Journal of the Optical Society of Korea, vol. 9, no. 3., pp. 107-110, 2005

C. Choi, K-S Soh, S.M. Lee, and G. Yoon, "Propagation of light along an Acupuncture meridian," Journal of the Optical Society of Korea, vol. 7, no. 4, pp. 245-248, 2003
[CrossRef]

Journal of the Royal Statistical Society. Series B (1)

M. Stone, "An asymptotic equivalence of choice of model by cross-validation and akaike"s criterion," J. R. Stat. Soc. B, vol. 38, pp. 44-47, 1977

Medical Instrumentation (1)

K. J. Fleckenstein, "The Mosso plethysmograph in 19th century physiology," Medical Instrumentation, vol. 18, pp. 330-331, 1984

Pro. 25 Ann. IEEE EMBS (1)

X.F. Teng and Y. T. Zhang, "Continuous and noninvasive estimation of arterial blood pressure using a photoplethysmographic approach," Pro. 25 Ann. IEEE EMBS, pp. 3153-3156, 2003

Other (4)

H. Hosaka, H. Sakata, Y. Sugo, T. Sohma, and H. Kasuya, "Pulse-wave propagation time basis blood pressure monitor," US patent, 5,649,543, 1998

Y. Chen, L. Li, C. Hershler, and R.P. Dill, "Continuous non-invasive blood pressure monitoring method and apparatus," US patent, 6,893,401 B2, 2005

J.G. Webster ed., Medical Instrumentation, 3rd edition (John Wiley & Sons, New York), PP. 324-328, 1998

J.G. Webster ed., Design of Pulse Oximeters (Institute of Physics Publishing, Bristol and Philadelphia, 1997), pp. 13-39

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