Abstract
Various methods have been investigated to increase photon density in soft
tissue, an important factor in low-level laser therapy. Previously we developed a
compression-controlled low-level laser probe (CCLLP) utilizing mechanical negative
compression, and experimentally verified its efficacy. In this study, we used Bezier
curves to numerically simulate the skin deformation and photon density variation
generated by the CCLLP. In addition, we numerically modeled changes in optical
coefficients due to skin deformation using a linearization technique with
appropriate parameterization. The simulated results were consistent with both human
in vivo and porcine ex vivo experimental results, confirming the efficacy of the
CCLLP.
© 2011 Optical Society of Korea
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