Abstract

There is a large demand for the development of portable easy-to-use on-chip biosensors capable of single molecule detection. In this paper, we propose a new ultrasensitive label-free optical refractive index sensor consisting of a Fabry–Perot resonator evanescently coupled to a microring resonator. The coupling between the Fabry–Perot standing wave mode and degenerate whispering gallery modes of the microring leads to a splitting of the resonances proportional to the coupling. Choosing the coupling region to be a microfluidic channel through which the analyte solution is pumped leads to a change in the splitting proportional to the index of refraction of the analyte that is immune to common-mode noise sources in the resonators such as thermal noise. The high sensitivity of the coupling to the analyte index combined with the reduced noise leads to significant improvement in the detection limit down to 109  RIU.

© 2017 Optical Society of America

Full Article  |  PDF Article
OSA Recommended Articles
Micro-capillary-based self-referencing surface plasmon resonance biosensor for determination of transferrin

Shimeng Chen, Yun Liu, Zigeng Liu, Shuwen Chu, and Wei Peng
Appl. Opt. 55(30) 8571-8575 (2016)

Fluorescent polymer coated capillaries as optofluidic refractometric sensors

Kristopher J. Rowland, Alexandre François, Peter Hoffmann, and Tanya M. Monro
Opt. Express 21(9) 11492-11505 (2013)

Silicon photonic micro-disk resonators for label-free biosensing

Samantha M. Grist, Shon A. Schmidt, Jonas Flueckiger, Valentina Donzella, Wei Shi, Sahba Talebi Fard, James T. Kirk, Daniel M. Ratner, Karen C. Cheung, and Lukas Chrostowski
Opt. Express 21(7) 7994-8006 (2013)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (6)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (20)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription