Abstract

Biomedical image mosaicking is a trending topic. It consists of computing a single large image from multiple observations and becomes a challenging task when said observations barely overlap or are subject to illumination changes, poor resolution, blur, or either highly textured or predominantly homogeneous content. Because such challenges are common in biomedical images, classical keypoint/feature-based methods perform poorly. In this paper, we propose a new framework based on pairwise template matching coupled with a constrained, confidence-driven global optimization strategy to solve the issue of microscopic biomedical image mosaicking. First we provide experimental results that show significant improvement on a subjective level. Then we describe a new validation strategy for objective assessment, which shows improvement as well.

© 2019 Optical Society of America

Full Article  |  PDF Article
More Like This
Radiometric framework for image mosaicking

Anatoly Litvinov and Yoav Y. Schechner
J. Opt. Soc. Am. A 22(5) 839-848 (2005)

Illuminant-invariant stereo matching using cost volume and confidence-based disparity refinement

Nakeun Choi, Jinbuem Jang, and Joonki Paik
J. Opt. Soc. Am. A 36(10) 1768-1776 (2019)

Wide-field and full-focus optical microscopic imaging system

Liguo Zhang, Guisheng Yin, Qilong Han, and Jianguo Sun
J. Opt. Soc. Am. A 36(6) 950-963 (2019)

References

You do not have subscription access to this journal. Citation lists with outbound citation links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Cited By

You do not have subscription access to this journal. Cited by links are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Figures (16)

You do not have subscription access to this journal. Figure files are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Tables (2)

You do not have subscription access to this journal. Article tables are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Equations (33)

You do not have subscription access to this journal. Equations are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription

Metrics

You do not have subscription access to this journal. Article level metrics are available to subscribers only. You may subscribe either as an OSA member, or as an authorized user of your institution.

Contact your librarian or system administrator
or
Login to access OSA Member Subscription