Abstract

An optical method for measuring the thickness of transparent structures has been developed, and has been used to measure, <i>in vivo</i>, the thickness of the human cornea. The thickness is measured by placing the anterior surface of the cornea at the focus of a beam of coherent laser light and then measuring the spacing between the interference fringes generated by the reflected light. The thickness is then calculated from the fringe spacing. The method has been used to measure corneal thickness in frog and human corneas. These measurements have been correlated with histologic and pachometer measurements of corneal thickness. A significant capability of this technique is to measure the thickness of optically opaque corneas.

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  2. M. Born and E. Wolf, Principles of Optics (Pergamon, New York, 1964).
  3. N. Ehlers, Acta Ophthalmol. Suppl. 81, 11 (1965).
  4. S. Mishima, Arch. Ophthalmol. 73, 233 (1965).
  5. M. S. Norn, Acta Ophthalmol. 44, 212 (1966).
  6. D. M. Maurice, Invest. Ophthalmol. 6, 464 (1967).
  7. H. Von Helmholtz, Handbuch der physiologischen Optik, 3te Aufi. (edited by Gullstrand, von Kries, Nagel, Hamburg, and Leipzig: Leopold Voss–English trans., with additions, edited by Southall, publ. 1924–5 by The Optical Society of America; 3 vols, 1, pp. 326–329). Reprinted by Dover, New York (1964).
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  9. N. Ehlers and F. K. Hansen, Acta Ophthalmol. 49, 65 (1971).
  10. H. Goldmann, Ber. Dtsche. Ophthalmol. Ges. 49, 435 (1932).
  11. D. M. Maurice and A. A. Giardini, Br. J. Ophthalmol. 35, 169 (1951).
  12. D. D. Donaldson, Arch. Ophthalmol. 76, 25 (1966).
  13. R. F. Lowe, Am. J. Ophthalmol. 62, 7 (1966).
  14. S. Mishima and B. O. Hedbys, Arch. Ophthalmol. 80, 710 (1968).
  15. Fizeau, C. R. Acad. Sci. (Paris) 54, 1237 (1862).
  16. Schweitzer, Arch. Ophthalmol. 77, 548 (1967).
  17. H. Goldmann and W. Lotmar, Klin. MbI. Augenheilk 154, 324 (1969).
  18. D. G. Green, Science 168, 1240 (1970).
  19. D. G. Green and M. M. Cohen, Trans. Am. Acad. Ophthalmol. Otolaryngol. 75, 629 (1971).
  20. R. J. Gstalder and D. G. Green, Arch. Ophthalmol. 87, 269 (1972).

von Bahr, G.

G. von Bahr, Acta Ophthalmol. 26, 247 (1948).

Von Helmholtz, H.

H. Von Helmholtz, Handbuch der physiologischen Optik, 3te Aufi. (edited by Gullstrand, von Kries, Nagel, Hamburg, and Leipzig: Leopold Voss–English trans., with additions, edited by Southall, publ. 1924–5 by The Optical Society of America; 3 vols, 1, pp. 326–329). Reprinted by Dover, New York (1964).

Born, M.

M. Born and E. Wolf, Principles of Optics (Pergamon, New York, 1964).

Cohen, M. M.

D. G. Green and M. M. Cohen, Trans. Am. Acad. Ophthalmol. Otolaryngol. 75, 629 (1971).

Donaldson, D. D.

D. D. Donaldson, Arch. Ophthalmol. 76, 25 (1966).

Ehlers, N.

N. Ehlers and F. K. Hansen, Acta Ophthalmol. 49, 65 (1971).

N. Ehlers, Acta Ophthalmol. Suppl. 81, 11 (1965).

Giardini, A. A.

D. M. Maurice and A. A. Giardini, Br. J. Ophthalmol. 35, 169 (1951).

Goldmann, H.

H. Goldmann and W. Lotmar, Klin. MbI. Augenheilk 154, 324 (1969).

H. Goldmann, Ber. Dtsche. Ophthalmol. Ges. 49, 435 (1932).

Goodman, J. W.

J. W. Goodman, Introduction to Fourier Optics (McGraw-Hill, San Francisco, 1968).

Green, D. G.

D. G. Green and M. M. Cohen, Trans. Am. Acad. Ophthalmol. Otolaryngol. 75, 629 (1971).

R. J. Gstalder and D. G. Green, Arch. Ophthalmol. 87, 269 (1972).

D. G. Green, Science 168, 1240 (1970).

Gstalder, R. J.

R. J. Gstalder and D. G. Green, Arch. Ophthalmol. 87, 269 (1972).

Hansen, F. K.

N. Ehlers and F. K. Hansen, Acta Ophthalmol. 49, 65 (1971).

Hedbys, B. O.

S. Mishima and B. O. Hedbys, Arch. Ophthalmol. 80, 710 (1968).

Lotmar, W.

H. Goldmann and W. Lotmar, Klin. MbI. Augenheilk 154, 324 (1969).

Lowe, R. F.

R. F. Lowe, Am. J. Ophthalmol. 62, 7 (1966).

Maurice, D. M.

D. M. Maurice and A. A. Giardini, Br. J. Ophthalmol. 35, 169 (1951).

D. M. Maurice, Invest. Ophthalmol. 6, 464 (1967).

Mishima, S.

S. Mishima, Arch. Ophthalmol. 73, 233 (1965).

S. Mishima and B. O. Hedbys, Arch. Ophthalmol. 80, 710 (1968).

Norn, M. S.

M. S. Norn, Acta Ophthalmol. 44, 212 (1966).

Wolf, E.

M. Born and E. Wolf, Principles of Optics (Pergamon, New York, 1964).

Other

J. W. Goodman, Introduction to Fourier Optics (McGraw-Hill, San Francisco, 1968).

M. Born and E. Wolf, Principles of Optics (Pergamon, New York, 1964).

N. Ehlers, Acta Ophthalmol. Suppl. 81, 11 (1965).

S. Mishima, Arch. Ophthalmol. 73, 233 (1965).

M. S. Norn, Acta Ophthalmol. 44, 212 (1966).

D. M. Maurice, Invest. Ophthalmol. 6, 464 (1967).

H. Von Helmholtz, Handbuch der physiologischen Optik, 3te Aufi. (edited by Gullstrand, von Kries, Nagel, Hamburg, and Leipzig: Leopold Voss–English trans., with additions, edited by Southall, publ. 1924–5 by The Optical Society of America; 3 vols, 1, pp. 326–329). Reprinted by Dover, New York (1964).

G. von Bahr, Acta Ophthalmol. 26, 247 (1948).

N. Ehlers and F. K. Hansen, Acta Ophthalmol. 49, 65 (1971).

H. Goldmann, Ber. Dtsche. Ophthalmol. Ges. 49, 435 (1932).

D. M. Maurice and A. A. Giardini, Br. J. Ophthalmol. 35, 169 (1951).

D. D. Donaldson, Arch. Ophthalmol. 76, 25 (1966).

R. F. Lowe, Am. J. Ophthalmol. 62, 7 (1966).

S. Mishima and B. O. Hedbys, Arch. Ophthalmol. 80, 710 (1968).

Fizeau, C. R. Acad. Sci. (Paris) 54, 1237 (1862).

Schweitzer, Arch. Ophthalmol. 77, 548 (1967).

H. Goldmann and W. Lotmar, Klin. MbI. Augenheilk 154, 324 (1969).

D. G. Green, Science 168, 1240 (1970).

D. G. Green and M. M. Cohen, Trans. Am. Acad. Ophthalmol. Otolaryngol. 75, 629 (1971).

R. J. Gstalder and D. G. Green, Arch. Ophthalmol. 87, 269 (1972).

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